General Information of DIG (ID: E0PC2L)
DIG Name
Polyethylene glycol 400
DIG Function
Coating agent; Diluent; Ointment base; Plasticizing agent; Solvent; Suppository base; lubricant
Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG
       ICD Disease Classification 01 Infectious/parasitic disease Click to Show/Hide
Minocycline
API Info
Streptococcus bacterial infection [ICD-11: 1C41]
[1]
Valacyclovir
API Info
Herpes zoster [ICD-11: 1E91]
[2]
Metronidazole
API Info
Amebiasis [ICD-11: 1A36]
[3]
Famciclovir
API Info
Genital herpes [ICD-11: 1A94]
[4]
Penicillin V
API Info
Pulmonary tuberculosis [ICD-11: 1B10]
[5]
Cefaclor
API Info
Clostridium difficile infection [ICD-11: 1A04]
[6]
Ciprofloxacin
API Info
Endocarditis [ICD-11: 1B12]
[7]
Griseofulvin
API Info
Dermatophytosis [ICD-11: 1F28]
[8]
Cefprozil
API Info
Streptococcus bacterial infection [ICD-11: 1C41]
[9]
Linezolid
API Info
Streptococcus bacterial infection [ICD-11: 1C41]
[10]
Raltegravir
API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
[11]
Chloroquine
API Info
Malaria [ICD-11: 1F40]
[12]
Entecavir
API Info
Viral hepatitis [ICD-11: 1E51]
[13]
Ritonavir
API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
[14]
Lamivudine
API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
[15]
Primaquine
API Info
Malaria [ICD-11: 1F40]
[16]
Valganciclovir
API Info
Cytomegalovirus infection [ICD-11: 1D82]
[17]
Zidovudine
API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
[18]
Daclatasvir
API Info
Viral hepatitis [ICD-11: 1E51]
[19]
Hydroxychloroquine
API Info
Malaria [ICD-11: 1F40]
[20]
Moxifloxacin
API Info
Streptococcus bacterial infection [ICD-11: 1C41]
[21]
Abacavir
API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
[22]
       ICD Disease Classification 02 Benign/in-situ/malignant neoplasm Click to Show/Hide
Nicotinic acid
API Info
Lung cancer [ICD-11: 2C25]
[23]
Bicalutamide
API Info
Prostate cancer [ICD-11: 2C82]
[24]
Letrozole
API Info
Breast cancer [ICD-11: 2C60]
[25]
Methotrexate
API Info
Breast cancer [ICD-11: 2C60]
[26]
Nystatin
API Info
Acute lymphoblastic leukemia [ICD-11: 2B33]
[27]
Olaparib
API Info
Ovarian cancer [ICD-11: 2C73]
[28]
Bexarotene
API Info
Anaplastic large cell lymphoma [ICD-11: 2A90]
[29]
Tamoxifen
API Info
Breast cancer [ICD-11: 2C60]
[30]
Lapatinib
API Info
Breast cancer [ICD-11: 2C60]
[31]
Midostaurin
API Info
Mastocytosis [ICD-11: 2A21]
[32]
Anastrozole
API Info
Breast cancer [ICD-11: 2C60]
[33]
Melphalan
API Info
Multiple myeloma [ICD-11: 2A83]
[34]
Pazopanib
API Info
Renal cell carcinoma [ICD-11: 2C90]
[35]
       ICD Disease Classification 03 Blood/blood-forming organ disease Click to Show/Hide
Eltrombopag
API Info
Thrombocytopenia [ICD-11: 3B64]
[36]
       ICD Disease Classification 04 Immune system disease Click to Show/Hide
Cetirizine
API Info
Allergy [ICD-11: 4A80]
[37]
       ICD Disease Classification 05 Endocrine/nutritional/metabolic disease Click to Show/Hide
Fenofibrate
API Info
Hypertriglyceridaemia [ICD-11: 5C80]
[38]
Glipizide
API Info
Diabetes mellitus [ICD-11: 5A10]
[39]
Lovastatin
API Info
Hypertriglyceridaemia [ICD-11: 5C80]
[40]
Metformin
API Info
Diabetes mellitus [ICD-11: 5A10]
[41]
Gemfibrozil
API Info
Hypertriglyceridaemia [ICD-11: 5C80]
[42]
Miglitol
API Info
Diabetic complication [ICD-11: 5A2Y]
[43]
       ICD Disease Classification 06 Mental/behavioural/neurodevelopmental disorder Click to Show/Hide
Risperidone
API Info
Schizophrenia [ICD-11: 6A20]
[44]
Bupropion
API Info
Nicotine dependence [ICD-11: 6C4A]
[45]
Lamotrigine
API Info
Bipolar disorder [ICD-11: 6A60]
[46]
Fluoxetine
API Info
Major depressive disorder [ICD-11: 6A70]
[47]
Duloxetine
API Info
Major depressive disorder [ICD-11: 6A70]
[48]
Venlafaxine
API Info
Major depressive disorder [ICD-11: 6A70]
[49]
Sertraline
API Info
Major depressive disorder [ICD-11: 6A70]
[50]
Amitriptyline
API Info
Major depressive disorder [ICD-11: 6A70]
[51]
Olanzapine
API Info
Schizophrenia [ICD-11: 6A20]
[52]
Hydroxyzine
API Info
Anxiety disorder [ICD-11: 6B00]
[53]
Dexmethylphenidate
API Info
Attention deficit hyperactivity disorder [ICD-11: 6A05]
[54]
Paroxetine
API Info
Major depressive disorder [ICD-11: 6A70]
[55]
Quetiapine
API Info
Schizophrenia [ICD-11: 6A20]
[56]
Lithium carbonate
API Info
Bipolar disorder [ICD-11: 6A60]
[57]
Cyclobenzaprine
API Info
Major depressive disorder [ICD-11: 6A70]
[58]
Mirtazapine
API Info
Major depressive disorder [ICD-11: 6A70]
[59]
Fluvoxamine
API Info
Obsessive-compulsive disorder [ICD-11: 6B20]
[60]
Escitalopram
API Info
Major depressive disorder [ICD-11: 6A70]
[61]
Citalopram
API Info
Major depressive disorder [ICD-11: 6A70]
[62]
Tranylcypromine
API Info
Major depressive disorder [ICD-11: 6A70]
[63]
Milnacipran
API Info
Asperger syndrome [ICD-11: 6A02]
[64]
Vortioxetine
API Info
Major depressive disorder [ICD-11: 6A70]
[65]
Protriptyline
API Info
Major depressive disorder [ICD-11: 6A70]
[66]
Acamprosate
API Info
Alcohol dependence [ICD-11: 6C40]
[67]
Naltrexone
API Info
Alcohol dependence [ICD-11: 6C40]
[68]
       ICD Disease Classification 07 Sleep-wake disorder Click to Show/Hide
Dextroamphetamine
API Info
Narcolepsy [ICD-11: 7A20]
[69]
Zolpidem
API Info
Insomnia [ICD-11: 7A00]
[70]
Eszopiclone
API Info
Insomnia [ICD-11: 7A00]
[71]
       ICD Disease Classification 08 Nervous system disease Click to Show/Hide
Acetaminophen
API Info
Anaesthesia [ICD-11: 8E22]
[72]
Morphine
API Info
Anaesthesia [ICD-11: 8E22]
[73]
Gabapentin
API Info
Focal seizure [ICD-11: 8A68]
[74]
Oxycodone
API Info
Anaesthesia [ICD-11: 8E22]
[75]
Valproic acid
API Info
Epilepsy [ICD-11: 8A60]
[76]
Propranolol
API Info
Migraine [ICD-11: 8A80]
[77]
Ropinirole
API Info
Parkinsonism [ICD-11: 8A00]
[78]
Levetiracetam
API Info
Focal seizure [ICD-11: 8A68]
[79]
Tramadol
API Info
Anaesthesia [ICD-11: 8E22]
[80]
Topiramate
API Info
Focal seizure [ICD-11: 8A68]
[81]
Galantamine
API Info
Alzheimer disease [ICD-11: 8A20]
[82]
Hydromorphone
API Info
Anaesthesia [ICD-11: 8E22]
[83]
Memantine
API Info
Alzheimer disease [ICD-11: 8A20]
[84]
Donepezil
API Info
Alzheimer disease [ICD-11: 8A20]
[85]
Zolmitriptan
API Info
Migraine [ICD-11: 8A80]
[86]
Sumatriptan
API Info
Migraine [ICD-11: 8A80]
[87]
Naratriptan
API Info
Migraine [ICD-11: 8A80]
[88]
Ethosuximide
API Info
Epilepsy [ICD-11: 8A60]
[89]
Ticagrelor
API Info
Cerebral stroke [ICD-11: 8B11]
[90]
Ticlopidine
API Info
Cerebral stroke [ICD-11: 8B11]
[91]
Riluzole
API Info
Amyotrophic lateral sclerosis [ICD-11: 8B60]
[92]
       ICD Disease Classification 09 Visual system disease Click to Show/Hide
Dextromethorphan
API Info
Allergic conjunctivitis [ICD-11: 9A60]
[93]
       ICD Disease Classification 10 Ear/mastoid process disease Click to Show/Hide
Diphenhydramine
API Info
Meniere disease [ICD-11: AB31]
[94]
Amoxicillin
API Info
Acute otitis media [ICD-11: AB00]
[95]
Cephalexin
API Info
Acute otitis media [ICD-11: AB00]
[96]
       ICD Disease Classification 11 Circulatory system disease Click to Show/Hide
Aspirin
API Info
Myocardial infarction [ICD-11: BA41]
[97]
Metoprolol
API Info
Essential hypertension [ICD-11: BA00]
[98]
Verapamil
API Info
Essential hypertension [ICD-11: BA00]
[99]
Losartan
API Info
Essential hypertension [ICD-11: BA00]
[100]
Caffeine
API Info
Orthostatic hypotension [ICD-11: BA21]
[101]
Felodipine
API Info
Essential hypertension [ICD-11: BA00]
[102]
Nifedipine
API Info
Angina pectoris [ICD-11: BA40]
[103]
Clopidogrel
API Info
Deep vein thrombosis [ICD-11: BD71]
[104]
Valsartan
API Info
Essential hypertension [ICD-11: BA00]
[105]
Benazepril
API Info
Essential hypertension [ICD-11: BA00]
[106]
Carvedilol
API Info
Congestive heart failure [ICD-11: BD10]
[107]
Spironolactone
API Info
Congestive heart failure [ICD-11: BD10]
[108]
Labetalol
API Info
Essential hypertension [ICD-11: BA00]
[109]
Betaxolol
API Info
Essential hypertension [ICD-11: BA00]
[110]
Bisoprolol
API Info
Essential hypertension [ICD-11: BA00]
[111]
Nimodipine
API Info
Cerebral vasospasm [ICD-11: BA85]
[112]
Quinapril
API Info
Essential hypertension [ICD-11: BA00]
[113]
Ranolazine
API Info
Angina pectoris [ICD-11: BA40]
[114]
       ICD Disease Classification 12 Respiratory system disease Click to Show/Hide
Montelukast
API Info
Asthma [ICD-11: CA23]
[115]
Clarithromycin
API Info
Pneumocystis pneumonia [ICD-11: CA40]
[116]
Fexofenadine
API Info
Allergic rhinitis [ICD-11: CA08]
[117]
Levofloxacin
API Info
Bronchitis [ICD-11: CA20]
[118]
Zileuton
API Info
Asthma [ICD-11: CA23]
[119]
Levocetirizine
API Info
Allergic rhinitis [ICD-11: CA08]
[120]
Ofloxacin
API Info
Pneumocystis pneumonia [ICD-11: CA40]
[121]
Zafirlukast
API Info
Asthma [ICD-11: CA23]
[122]
       ICD Disease Classification 13 Digestive system disease Click to Show/Hide
Doxycycline
API Info
Periodontal disease [ICD-11: DA0C]
[123]
Bisacodyl
API Info
Irritable bowel syndrome [ICD-11: DD91]
[124]
Pantoprazole
API Info
Gastro-oesophageal reflux disease [ICD-11: DA22]
[125]
Lansoprazole
API Info
Duodenal ulcer [ICD-11: DA63]
[126]
Ranitidine
API Info
Gastric ulcer [ICD-11: DA60]
[127]
Ondansetron
API Info
Gastritis [ICD-11: DA42]
[128]
Mycophenolate mofetil
API Info
Crohn disease [ICD-11: DD70]
[129]
Ursodeoxycholic acid
API Info
Hepatic fibrosis/cirrhosis [ICD-11: DB93]
[130]
Famotidine
API Info
Peptic ulcer [ICD-11: DA61]
[131]
Naloxegol
API Info
Irritable bowel syndrome [ICD-11: DD91]
[132]
Granisetron
API Info
Functional nausea/vomiting [ICD-11: DD90]
[133]
       ICD Disease Classification 14 Skin disease Click to Show/Hide
Pseudoephedrine
API Info
Erythema multiforme [ICD-11: EB12]
[134]
Demeclocycline
API Info
Acne vulgaris [ICD-11: ED80]
[135]
       ICD Disease Classification 15 Musculoskeletal/connective-tissue disease Click to Show/Hide
Naproxen
API Info
Rheumatoid arthritis [ICD-11: FA20]
[136]
Diclofenac
API Info
Knee osteoarthritis [ICD-11: FA01]
[137]
Etodolac
API Info
Rheumatoid arthritis [ICD-11: FA20]
[138]
Nabumetone
API Info
Rheumatoid arthritis [ICD-11: FA20]
[139]
Phenylephrine
API Info
Juvenile rheumatoid arthritis [ICD-11: FA24]
[140]
Cyclosporin A
API Info
Rheumatoid arthritis [ICD-11: FA20]
[141]
Conjugated estrogen
API Info
Osteoporosis [ICD-11: FB83]
[142]
Risedronic acid
API Info
Paget's disease [ICD-11: FB85]
[143]
Diflunisal
API Info
Osteoporosis [ICD-11: FB83]
[144]
Ibandronic acid
API Info
Osteoporosis [ICD-11: FB83]
[145]
Flurbiprofen
API Info
Rheumatoid arthritis [ICD-11: FA20]
[146]
Oxaprozin
API Info
Rheumatoid arthritis [ICD-11: FA20]
[147]
Raloxifene
API Info
Osteoporosis [ICD-11: FB83]
[148]
Ketorolac
API Info
Rheumatoid arthritis [ICD-11: FA20]
[149]
Flavoxate
API Info
Knee osteoarthritis [ICD-11: FA01]
[150]
       ICD Disease Classification 16 Genitourinary system disease Click to Show/Hide
Ibuprofen
API Info
Dysmenorrhea [ICD-11: GA34]
[151]
Finasteride
API Info
Prostatic hyperplasia [ICD-11: GA90]
[152]
Oxybutynin
API Info
Overactive bladder [ICD-11: GC50]
[153]
Progesterone
API Info
Endometrial hyperplasia [ICD-11: GA16]
[154]
Phenazopyridine
API Info
Infectious cystitis [ICD-11: GC00]
[155]
Trospium
API Info
Overactive bladder [ICD-11: GC50]
[156]
Darifenacin
API Info
Overactive bladder [ICD-11: GC50]
[157]
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG
      Oxidoreductase (ORase)
            DBT Name: Albendazole monooxygenase (CYP3A4) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 = 10.77 mg.mL-1 (tested by experiment) [158]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CP3A4_HUMAN
      Primary active transporter (PAT)
            DBT Name: Multidrug resistance protein 2 (ABCC2) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment (1) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Inhibition ratio = 67 % (tested by experiment) [159]
                    Tested Species Homo sapiens (Human)
                    UniProt ID MRP2_HUMAN
               Experiment (2) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Inhibition ratio > 73 % (tested by experiment) [160]
                    Tested Species Homo sapiens (Human)
                    UniProt ID MRP2_HUMAN
            DBT Name: Multidrug resistance protein 1 (ABCB1) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment (1) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Inhibition ratio = 28 % (tested by experiment) [161]
                    Tested Species Homo sapiens (Human)
                    UniProt ID MDR1_HUMAN ; MDR3_HUMAN ; ABCB5_HUMAN
               Experiment (2) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Inhibition ratio = 64 % (tested by experiment) [162]
                    Tested Species Homo sapiens (Human)
                    UniProt ID MDR1_HUMAN ; MDR3_HUMAN ; ABCB5_HUMAN
      Potential-driven transporter (PDT)
            DBT Name: Solute carrier SLCO1A2 (OATP-A) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment (1) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 = 0.14 %(w/v) (tested by experiment) [163]
                    Tested Species Homo sapiens (Human)
                    UniProt ID SO1A2_HUMAN
               Experiment (2) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 = 0.05 %(w/v) (tested by experiment) [163]
                    Tested Species Homo sapiens (Human)
                    UniProt ID SO1A2_HUMAN
References
1 FDA label for approved minocycline from the official website of the U.S. Food and Drug Administration.
2 FDA label for approved valacyclovir from the official website of the U.S. Food and Drug Administration.
3 FDA label for approved metronidazole from the official website of the U.S. Food and Drug Administration.
4 FDA label for approved famciclovir from the official website of the U.S. Food and Drug Administration.
5 FDA label for approved penicillin V from the official website of the U.S. Food and Drug Administration.
6 FDA label for approved cefaclor from the official website of the U.S. Food and Drug Administration.
7 FDA label for approved ciprofloxacin from the official website of the U.S. Food and Drug Administration.
8 FDA label for approved griseofulvin from the official website of the U.S. Food and Drug Administration.
9 FDA label for approved cefprozil from the official website of the U.S. Food and Drug Administration.
10 FDA label for approved linezolid from the official website of the U.S. Food and Drug Administration.
11 2007 FDA drug approvals: a year of flux. Nat Rev Drug Discov. 2008 Feb;7(2):107-9.
12 FDA label for approved chloroquine from the official website of the U.S. Food and Drug Administration.
13 FDA label for approved entecavir from the official website of the U.S. Food and Drug Administration.
14 FDA label for approved ritonavir from the official website of the U.S. Food and Drug Administration.
15 FDA label for approved lamivudine from the official website of the U.S. Food and Drug Administration.
16 FDA label for approved primaquine from the official website of the U.S. Food and Drug Administration.
17 FDA label for approved valganciclovir from the official website of the U.S. Food and Drug Administration.
18 FDA label for approved zidovudine from the official website of the U.S. Food and Drug Administration.
19 FDA label for approved daclatasvir from the official website of the U.S. Food and Drug Administration.
20 FDA label for approved hydroxychloroquine from the official website of the U.S. Food and Drug Administration.
21 FDA label for approved moxifloxacin from the official website of the U.S. Food and Drug Administration.
22 FDA label for approved abacavir from the official website of the U.S. Food and Drug Administration.
23 FDA label for approved nicotinic acid from the official website of the U.S. Food and Drug Administration.
24 FDA label for approved bicalutamide from the official website of the U.S. Food and Drug Administration.
25 FDA label for approved letrozole from the official website of the U.S. Food and Drug Administration.
26 FDA label for approved methotrexate from the official website of the U.S. Food and Drug Administration.
27 FDA label for approved nystatin from the official website of the U.S. Food and Drug Administration.
28 FDA label for approved olaparib from the official website of the U.S. Food and Drug Administration.
29 FDA label for approved bexarotene from the official website of the U.S. Food and Drug Administration.
30 FDA label for approved tamoxifen from the official website of the U.S. Food and Drug Administration.
31 FDA label for approved lapatinib from the official website of the U.S. Food and Drug Administration.
32 FDA label for approved midostaurin from the official website of the U.S. Food and Drug Administration.
33 FDA label for approved anastrozole from the official website of the U.S. Food and Drug Administration.
34 FDA label for approved melphalan from the official website of the U.S. Food and Drug Administration.
35 FDA label for approved pazopanib from the official website of the U.S. Food and Drug Administration.
36 FDA label for approved eltrombopag from the official website of the U.S. Food and Drug Administration.
37 FDA label for approved cetirizine from the official website of the U.S. Food and Drug Administration.
38 FDA label for approved fenofibrate from the official website of the U.S. Food and Drug Administration.
39 FDA label for approved glipizide from the official website of the U.S. Food and Drug Administration.
40 FDA label for approved lovastatin from the official website of the U.S. Food and Drug Administration.
41 FDA label for approved metformin from the official website of the U.S. Food and Drug Administration.
42 FDA label for approved gemfibrozil from the official website of the U.S. Food and Drug Administration.
43 FDA label for approved miglitol from the official website of the U.S. Food and Drug Administration.
44 FDA label for approved risperidone from the official website of the U.S. Food and Drug Administration.
45 FDA label for approved bupropion from the official website of the U.S. Food and Drug Administration.
46 FDA label for approved lamotrigine from the official website of the U.S. Food and Drug Administration.
47 FDA label for approved fluoxetine from the official website of the U.S. Food and Drug Administration.
48 FDA label for approved duloxetine from the official website of the U.S. Food and Drug Administration.
49 FDA label for approved venlafaxine from the official website of the U.S. Food and Drug Administration.
50 FDA label for approved sertraline from the official website of the U.S. Food and Drug Administration.
51 FDA label for approved amitriptyline from the official website of the U.S. Food and Drug Administration.
52 FDA label for approved olanzapine from the official website of the U.S. Food and Drug Administration.
53 FDA label for approved hydroxyzine from the official website of the U.S. Food and Drug Administration.
54 FDA label for approved dexmethylphenidate from the official website of the U.S. Food and Drug Administration.
55 FDA label for approved paroxetine from the official website of the U.S. Food and Drug Administration.
56 FDA label for approved quetiapine from the official website of the U.S. Food and Drug Administration.
57 FDA label for approved lithium carbonate from the official website of the U.S. Food and Drug Administration.
58 FDA label for approved cyclobenzaprine from the official website of the U.S. Food and Drug Administration.
59 FDA label for approved mirtazapine from the official website of the U.S. Food and Drug Administration.
60 FDA label for approved fluvoxamine from the official website of the U.S. Food and Drug Administration.
61 FDA label for approved escitalopram from the official website of the U.S. Food and Drug Administration.
62 FDA label for approved citalopram from the official website of the U.S. Food and Drug Administration.
63 FDA label for approved tranylcypromine from the official website of the U.S. Food and Drug Administration.
64 FDA label for approved milnacipran from the official website of the U.S. Food and Drug Administration.
65 FDA label for approved vortioxetine from the official website of the U.S. Food and Drug Administration.
66 FDA label for approved protriptyline from the official website of the U.S. Food and Drug Administration.
67 FDA label for approved acamprosate from the official website of the U.S. Food and Drug Administration.
68 FDA label for approved naltrexone from the official website of the U.S. Food and Drug Administration.
69 FDA label for approved dextroamphetamine from the official website of the U.S. Food and Drug Administration.
70 FDA label for approved zolpidem from the official website of the U.S. Food and Drug Administration.
71 FDA label for approved eszopiclone from the official website of the U.S. Food and Drug Administration.
72 FDA label for approved acetaminophen from the official website of the U.S. Food and Drug Administration.
73 FDA label for approved morphine from the official website of the U.S. Food and Drug Administration.
74 FDA label for approved gabapentin from the official website of the U.S. Food and Drug Administration.
75 Efficacy of oxycodone in neuropathic pain: a randomized trial in postherpetic neuralgia. Neurology. 1998 Jun;50(6):1837-41.
76 FDA label for approved valproic acid from the official website of the U.S. Food and Drug Administration.
77 FDA label for approved propranolol from the official website of the U.S. Food and Drug Administration.
78 FDA label for approved ropinirole from the official website of the U.S. Food and Drug Administration.
79 FDA label for approved levetiracetam from the official website of the U.S. Food and Drug Administration.
80 FDA label for approved tramadol from the official website of the U.S. Food and Drug Administration.
81 FDA label for approved topiramate from the official website of the U.S. Food and Drug Administration.
82 FDA label for approved galantamine from the official website of the U.S. Food and Drug Administration.
83 FDA label for approved hydromorphone from the official website of the U.S. Food and Drug Administration.
84 FDA label for approved memantine from the official website of the U.S. Food and Drug Administration.
85 FDA label for approved donepezil from the official website of the U.S. Food and Drug Administration.
86 FDA label for approved zolmitriptan from the official website of the U.S. Food and Drug Administration.
87 FDA label for approved sumatriptan from the official website of the U.S. Food and Drug Administration.
88 FDA label for approved naratriptan from the official website of the U.S. Food and Drug Administration.
89 FDA label for approved ethosuximide from the official website of the U.S. Food and Drug Administration.
90 FDA label for approved ticagrelor from the official website of the U.S. Food and Drug Administration.
91 FDA label for approved ticlopidine from the official website of the U.S. Food and Drug Administration.
92 FDA label for approved riluzole from the official website of the U.S. Food and Drug Administration.
93 FDA label for approved dextromethorphan from the official website of the U.S. Food and Drug Administration.
94 FDA label for approved diphenhydramine from the official website of the U.S. Food and Drug Administration.
95 FDA label for approved amoxicillin from the official website of the U.S. Food and Drug Administration.
96 FDA label for approved cephalexin from the official website of the U.S. Food and Drug Administration.
97 FDA label for approved aspirin from the official website of the U.S. Food and Drug Administration.
98 FDA label for approved metoprolol from the official website of the U.S. Food and Drug Administration.
99 FDA label for approved verapamil from the official website of the U.S. Food and Drug Administration.
100 FDA label for approved losartan from the official website of the U.S. Food and Drug Administration.
101 FDA label for approved caffeine from the official website of the U.S. Food and Drug Administration.
102 FDA label for approved felodipine from the official website of the U.S. Food and Drug Administration.
103 FDA label for approved nifedipine from the official website of the U.S. Food and Drug Administration.
104 FDA label for approved clopidogrel from the official website of the U.S. Food and Drug Administration.
105 FDA label for approved valsartan from the official website of the U.S. Food and Drug Administration.
106 FDA label for approved benazepril from the official website of the U.S. Food and Drug Administration.
107 FDA label for approved carvedilol from the official website of the U.S. Food and Drug Administration.
108 FDA label for approved spironolactone from the official website of the U.S. Food and Drug Administration.
109 FDA label for approved labetalol from the official website of the U.S. Food and Drug Administration.
110 FDA label for approved betaxolol from the official website of the U.S. Food and Drug Administration.
111 FDA label for approved bisoprolol from the official website of the U.S. Food and Drug Administration.
112 FDA label for approved nimodipine from the official website of the U.S. Food and Drug Administration.
113 FDA label for approved quinapril from the official website of the U.S. Food and Drug Administration.
114 FDA label for approved ranolazine from the official website of the U.S. Food and Drug Administration.
115 FDA label for approved montelukast from the official website of the U.S. Food and Drug Administration.
116 FDA label for approved clarithromycin from the official website of the U.S. Food and Drug Administration.
117 FDA label for approved fexofenadine from the official website of the U.S. Food and Drug Administration.
118 FDA label for approved levofloxacin from the official website of the U.S. Food and Drug Administration.
119 FDA label for approved zileuton from the official website of the U.S. Food and Drug Administration.
120 FDA label for approved levocetirizine from the official website of the U.S. Food and Drug Administration.
121 FDA label for approved ofloxacin from the official website of the U.S. Food and Drug Administration.
122 FDA label for approved zafirlukast from the official website of the U.S. Food and Drug Administration.
123 FDA label for approved doxycycline from the official website of the U.S. Food and Drug Administration.
124 FDA label for approved bisacodyl from the official website of the U.S. Food and Drug Administration.
125 FDA label for approved pantoprazole from the official website of the U.S. Food and Drug Administration.
126 FDA label for approved lansoprazole from the official website of the U.S. Food and Drug Administration.
127 FDA label for approved ranitidine from the official website of the U.S. Food and Drug Administration.
128 FDA label for approved ondansetron from the official website of the U.S. Food and Drug Administration.
129 FDA label for approved mycophenolate mofetil from the official website of the U.S. Food and Drug Administration.
130 FDA label for approved ursodeoxycholic acid from the official website of the U.S. Food and Drug Administration.
131 FDA label for approved famotidine from the official website of the U.S. Food and Drug Administration.
132 FDA label for approved naldemedine from the official website of the U.S. Food and Drug Administration.
133 FDA label for approved granisetron from the official website of the U.S. Food and Drug Administration.
134 A study of sustained action pseudoephedrine in allergic rhinitis. Ann Allergy. 1982 Feb;48(2):87-92.
135 FDA label for approved demeclocycline from the official website of the U.S. Food and Drug Administration.
136 FDA label for approved naproxen from the official website of the U.S. Food and Drug Administration.
137 FDA label for approved diclofenac from the official website of the U.S. Food and Drug Administration.
138 FDA label for approved etodolac from the official website of the U.S. Food and Drug Administration.
139 FDA label for approved nabumetone from the official website of the U.S. Food and Drug Administration.
140 FDA label for approved phenylephrine from the official website of the U.S. Food and Drug Administration.
141 FDA label for approved cyclosporin A from the official website of the U.S. Food and Drug Administration.
142 FDA label for approved conjugated estrogen from the official website of the U.S. Food and Drug Administration.
143 FDA label for approved risedronic acid from the official website of the U.S. Food and Drug Administration.
144 FDA label for approved diflunisal from the official website of the U.S. Food and Drug Administration.
145 FDA label for approved ibandronic acid from the official website of the U.S. Food and Drug Administration.
146 FDA label for approved flurbiprofen from the official website of the U.S. Food and Drug Administration.
147 FDA label for approved oxaprozin from the official website of the U.S. Food and Drug Administration.
148 FDA label for approved raloxifene from the official website of the U.S. Food and Drug Administration.
149 FDA label for approved ketorolac from the official website of the U.S. Food and Drug Administration.
150 Agents for treatment of overactive bladder: a therapeutic class review. Proc (Bayl Univ Med Cent). 2007 Jul;20(3):307-14.
151 FDA label for approved ibuprofen from the official website of the U.S. Food and Drug Administration.
152 FDA label for approved finasteride from the official website of the U.S. Food and Drug Administration.
153 FDA label for approved oxybutynin from the official website of the U.S. Food and Drug Administration.
154 FDA label for approved progesterone from the official website of the U.S. Food and Drug Administration.
155 FDA label for approved phenazopyridine from the official website of the U.S. Food and Drug Administration.
156 FDA label for approved trospium from the official website of the U.S. Food and Drug Administration.
157 FDA label for approved darifenacin from the official website of the U.S. Food and Drug Administration.
158 Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration. Eur J Pharm Biopharm. 2008 Sep;70(1):279-88.
159 Inhibition of human efflux transporter ABCC2 (MRP2) by self-emulsifying drug delivery system: influences of concentration and combination of excipients. J Pharm Pharm Sci. 2014;17(4):447-60.
160 Interactions between human multidrug resistance related protein (MRP2; ABCC2) and excipients commonly used in self-emulsifying drug delivery systems (SEDDS). Int J Pharm. 2013 Apr 15;447(1-2):192-8.
161 The effect of polyoxyethylene polymers on the transport of ranitidine in Caco-2 cell monolayers. Int J Pharm. 2011 May 16;409(1-2):164-8.
162 Modulation of intestinal P-glycoprotein function by polyethylene glycols and their derivatives by in vitro transport and in situ absorption studies. Int J Pharm. 2006 Apr 26;313(1-2):49-56.
163 Pharmaceutical excipients influence the function of human uptake transporting proteins. Mol Pharm. 2012 Sep 4;9(9):2577-81.

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