Details of the Drug Inactive Ingredient (DIG)
Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG | ||||||
---|---|---|---|---|---|---|
ICD Disease Classification 01 | Infectious/parasitic disease | Click to Show/Hide | ||||
Fluconazole
|
API Info |
Candidiasis [ICD-11: 1F23]
|
[1] | |||
Azithromycin
|
API Info |
Congenital syphilis [ICD-11: 1A60]
|
[2] | |||
Minocycline
|
API Info |
Streptococcus bacterial infection [ICD-11: 1C41]
|
[3] | |||
Metronidazole
|
API Info |
Amebiasis [ICD-11: 1A36]
|
[4] | |||
Acyclovir
|
API Info |
Herpes zoster [ICD-11: 1E91]
|
[5] | |||
Amantadine
|
API Info |
Influenza virus infection [ICD-11: 1E30]
|
[6] | |||
Didanosine
|
API Info |
Human immunodeficiency virus infection [ICD-11: 1C60]
|
[7] | |||
Oseltamivir
|
API Info |
Influenza virus infection [ICD-11: 1E30]
|
[8] | |||
Stavudine
|
API Info |
Human immunodeficiency virus infection [ICD-11: 1C60]
|
[9] | |||
Tetracycline
|
API Info |
Spotted fever [ICD-11: 1C31]
|
[10] | |||
Dicloxacillin
|
API Info |
Streptococcus bacterial infection [ICD-11: 1C41]
|
[11] | |||
Vancomycin
|
API Info |
Methicillin-resistant staphylococcus infection [ICD-11: 1D01]
|
[12] | |||
Cefaclor
|
API Info |
Clostridium difficile infection [ICD-11: 1A04]
|
[13] | |||
Flucytosine
|
API Info |
Cryptococcosis [ICD-11: 1F27]
|
[14] | |||
Itraconazole
|
API Info |
Blastomycosis [ICD-11: 1F22]
|
[15] | |||
Tinidazole
|
API Info |
Amebiasis [ICD-11: 1A36]
|
[16] | |||
Cefprozil
|
API Info |
Streptococcus bacterial infection [ICD-11: 1C41]
|
[17] | |||
Cefixime
|
API Info |
Streptococcus bacterial infection [ICD-11: 1C41]
|
[18] | |||
Entecavir
|
API Info |
Viral hepatitis [ICD-11: 1E51]
|
[19] | |||
Primaquine
|
API Info |
Malaria [ICD-11: 1F40]
|
[20] | |||
Paromomycin
|
API Info |
Amebiasis [ICD-11: 1A36]
|
[21] | |||
Tenofovir disoproxil
|
API Info |
Human immunodeficiency virus infection [ICD-11: 1C60]
|
[22] | |||
Boceprevir
|
API Info |
Viral hepatitis [ICD-11: 1E51]
|
[23] | |||
Telaprevir
|
API Info |
Viral hepatitis [ICD-11: 1E51]
|
[24] | |||
ICD Disease Classification 02 | Benign/in-situ/malignant neoplasm | Click to Show/Hide | ||||
Temozolomide
|
API Info |
Brain cancer [ICD-11: 2A00]
|
[25] | |||
Hydroxyurea
|
API Info |
Chronic myelogenous leukaemia [ICD-11: 2A20]
|
[26] | |||
Letrozole
|
API Info |
Breast cancer [ICD-11: 2C60]
|
[27] | |||
Flutamide
|
API Info |
Prostate cancer [ICD-11: 2C82]
|
[28] | |||
Methotrexate
|
API Info |
Breast cancer [ICD-11: 2C60]
|
[29] | |||
Cyclophosphamide
|
API Info |
Multiple myeloma [ICD-11: 2A83]
|
[30] | |||
Nystatin
|
API Info |
Acute lymphoblastic leukemia [ICD-11: 2B33]
|
[31] | |||
Methyltestosterone
|
API Info |
Breast cancer [ICD-11: 2C60]
|
[32] | |||
Capecitabine
|
API Info |
Colon cancer [ICD-11: 2B90]
|
[33] | |||
Etoposide
|
API Info |
Testicular carcinoma [ICD-11: 2C80]
|
[34] | |||
ICD Disease Classification 03 | Blood/blood-forming organ disease | Click to Show/Hide | ||||
Anagrelide
|
API Info |
Thrombocytosis [ICD-11: 3B63]
|
[35] | |||
ICD Disease Classification 04 | Immune system disease | Click to Show/Hide | ||||
Cetirizine
|
API Info |
Allergy [ICD-11: 4A80]
|
[36] | |||
Cevimeline
|
API Info |
Sjogren syndrome [ICD-11: 4A43]
|
[37] | |||
ICD Disease Classification 05 | Endocrine/nutritional/metabolic disease | Click to Show/Hide | ||||
Levothroid
|
API Info |
Hypothyroidism [ICD-11: 5A00]
|
[38] | |||
Fenofibrate
|
API Info |
Hypertriglyceridaemia [ICD-11: 5C80]
|
[39] | |||
Simvastatin
|
API Info |
Dyslipidaemia [ICD-11: 5C81]
|
[40] | |||
Phentermine
|
API Info |
Obesity [ICD-11: 5B81]
|
[41] | |||
Potassium chloride
|
API Info |
Hypokalemia [ICD-11: 5C77]
|
[42] | |||
Glipizide
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[43] | |||
Glyburide
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[44] | |||
Rosuvastatin
|
API Info |
Hypertriglyceridaemia [ICD-11: 5C80]
|
[45] | |||
Phendimetrazine
|
API Info |
Obesity [ICD-11: 5B81]
|
[46] | |||
Calcium acetate
|
API Info |
Hyperphosphatemia [ICD-11: 5C64]
|
[47] | |||
Fenofibric acid
|
API Info |
Dyslipidaemia [ICD-11: 5C81]
|
[48] | |||
Benzphetamine
|
API Info |
Obesity [ICD-11: 5B81]
|
[49] | |||
Bromocriptine
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[50] | |||
Nateglinide
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[51] | |||
Doxercalciferol
|
API Info |
Hyperparathyroidism [ICD-11: 5A51]
|
[52] | |||
Zinc acetate
|
API Info |
Hyperphosphatemia [ICD-11: 5C64]
|
[53] | |||
ICD Disease Classification 06 | Mental/behavioural/neurodevelopmental disorder | Click to Show/Hide | ||||
Risperidone
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[54] | |||
Bupropion
|
API Info |
Nicotine dependence [ICD-11: 6C4A]
|
[55] | |||
Alprazolam
|
API Info |
Anxiety disorder [ICD-11: 6B00]
|
[56] | |||
Lamotrigine
|
API Info |
Bipolar disorder [ICD-11: 6A60]
|
[57] | |||
Fluoxetine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[58] | |||
Duloxetine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[59] | |||
Venlafaxine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[60] | |||
Sertraline
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[61] | |||
Amitriptyline
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[62] | |||
Aripiprazole
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[63] | |||
Hydroxyzine
|
API Info |
Anxiety disorder [ICD-11: 6B00]
|
[64] | |||
Methylphenidate
|
API Info |
Attention deficit hyperactivity disorder [ICD-11: 6A05]
|
[65] | |||
Dexmethylphenidate
|
API Info |
Attention deficit hyperactivity disorder [ICD-11: 6A05]
|
[66] | |||
Ziprasidone
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[67] | |||
Paroxetine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[68] | |||
Atomoxetine
|
API Info |
Attention deficit hyperactivity disorder [ICD-11: 6A05]
|
[69] | |||
Quetiapine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[70] | |||
Guanfacine
|
API Info |
Attention deficit hyperactivity disorder [ICD-11: 6A05]
|
[71] | |||
Lithium carbonate
|
API Info |
Bipolar disorder [ICD-11: 6A60]
|
[72] | |||
Cyclobenzaprine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[73] | |||
Nortriptyline
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[74] | |||
Imipramine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[75] | |||
Prochlorperazine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[76] | |||
Sinequan
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[77] | |||
Desipramine
|
API Info |
Attention deficit hyperactivity disorder [ICD-11: 6A05]
|
[78] | |||
Fluvoxamine
|
API Info |
Obsessive-compulsive disorder [ICD-11: 6B20]
|
[79] | |||
Loxapine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[80] | |||
Fluphenazine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[81] | |||
Clozapine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[82] | |||
Chlordiazepoxide
|
API Info |
Anxiety disorder [ICD-11: 6B00]
|
[83] | |||
Lisdexamfetamine
|
API Info |
Attention deficit hyperactivity disorder [ICD-11: 6A05]
|
[84] | |||
Paliperidone
|
API Info |
Bipolar disorder [ICD-11: 6A60]
|
[85] | |||
Citalopram
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[86] | |||
Clomipramine
|
API Info |
Obsessive-compulsive disorder [ICD-11: 6B20]
|
[87] | |||
Dronabinol
|
API Info |
Anorexia nervosa [ICD-11: 6B80]
|
[88] | |||
Tiotixene
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[89] | |||
Trimipramine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[90] | |||
Oxazepam
|
API Info |
Anxiety disorder [ICD-11: 6B00]
|
[91] | |||
Tranylcypromine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[92] | |||
Milnacipran
|
API Info |
Asperger syndrome [ICD-11: 6A02]
|
[93] | |||
Protriptyline
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[94] | |||
Vilazodone
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[95] | |||
Cariprazine
|
API Info |
Bipolar disorder [ICD-11: 6A60]
|
[96] | |||
Molindone
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[97] | |||
Naltrexone
|
API Info |
Alcohol dependence [ICD-11: 6C40]
|
[98] | |||
ICD Disease Classification 07 | Sleep-wake disorder | Click to Show/Hide | ||||
Dextroamphetamine
|
API Info |
Narcolepsy [ICD-11: 7A20]
|
[99] | |||
Temazepam
|
API Info |
Insomnia [ICD-11: 7A00]
|
[100] | |||
Zolpidem
|
API Info |
Insomnia [ICD-11: 7A00]
|
[101] | |||
Eszopiclone
|
API Info |
Insomnia [ICD-11: 7A00]
|
[102] | |||
Zaleplon
|
API Info |
Insomnia [ICD-11: 7A00]
|
[103] | |||
Flurazepam
|
API Info |
Insomnia [ICD-11: 7A00]
|
[104] | |||
Estazolam
|
API Info |
Insomnia [ICD-11: 7A00]
|
[105] | |||
ICD Disease Classification 08 | Nervous system disease | Click to Show/Hide | ||||
Acetaminophen
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[106] | |||
Morphine
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[107] | |||
Gabapentin
|
API Info |
Focal seizure [ICD-11: 8A68]
|
[108] | |||
Oxycodone
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[109] | |||
Valproic acid
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[110] | |||
Propranolol
|
API Info |
Migraine [ICD-11: 8A80]
|
[111] | |||
Ropinirole
|
API Info |
Parkinsonism [ICD-11: 8A00]
|
[112] | |||
Levetiracetam
|
API Info |
Focal seizure [ICD-11: 8A68]
|
[113] | |||
Carbamazepine
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[114] | |||
Tizanidine
|
API Info |
Tic disorder [ICD-11: 8A05]
|
[115] | |||
Topiramate
|
API Info |
Focal seizure [ICD-11: 8A68]
|
[116] | |||
Oxymorphone
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[117] | |||
Phenytoin
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[118] | |||
Galantamine
|
API Info |
Alzheimer disease [ICD-11: 8A20]
|
[119] | |||
Hydromorphone
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[120] | |||
Zonisamide
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[121] | |||
Hydrocodone
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[122] | |||
Rivastigmine
|
API Info |
Alzheimer disease [ICD-11: 8A20]
|
[123] | |||
Ketoprofen
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[124] | |||
Dantrolene
|
API Info |
Hyperthermia [ICD-11: 8C78]
|
[125] | |||
Carbidopa
|
API Info |
Parkinsonism [ICD-11: 8A00]
|
[126] | |||
Naratriptan
|
API Info |
Migraine [ICD-11: 8A80]
|
[127] | |||
Felbamate
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[128] | |||
Ethosuximide
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[129] | |||
Deutetrabenazine
|
API Info |
Huntington disease [ICD-11: 8A01]
|
[130] | |||
Droxidopa
|
API Info |
Neurogenic orthostatic hypotension [ICD-11: 8D87]
|
[131] | |||
Pentosan polysulfate
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[132] | |||
Valbenazine
|
API Info |
Dyskinesia [ICD-11: 8A02]
|
[133] | |||
ICD Disease Classification 09 | Visual system disease | Click to Show/Hide | ||||
Dextromethorphan
|
API Info |
Allergic conjunctivitis [ICD-11: 9A60]
|
[134] | |||
Acetazolamide
|
API Info |
Glaucoma [ICD-11: 9C61]
|
[135] | |||
ICD Disease Classification 10 | Ear/mastoid process disease | Click to Show/Hide | ||||
Diphenhydramine
|
API Info |
Meniere disease [ICD-11: AB31]
|
[136] | |||
Amoxicillin
|
API Info |
Acute otitis media [ICD-11: AB00]
|
[137] | |||
Cephalexin
|
API Info |
Acute otitis media [ICD-11: AB00]
|
[138] | |||
ICD Disease Classification 11 | Circulatory system disease | Click to Show/Hide | ||||
Diltiazem
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[139] | |||
Aspirin
|
API Info |
Myocardial infarction [ICD-11: BA41]
|
[140] | |||
Metoprolol
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[141] | |||
Warfarin
|
API Info |
Atrial fibrillation [ICD-11: BC81]
|
[142] | |||
Ramipril
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[143] | |||
Verapamil
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[144] | |||
Hydralazine
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[145] | |||
Clonidine
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[146] | |||
Doxazosin
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[147] | |||
Enalapril
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[148] | |||
Caffeine
|
API Info |
Orthostatic hypotension [ICD-11: BA21]
|
[149] | |||
Felodipine
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[150] | |||
Nifedipine
|
API Info |
Angina pectoris [ICD-11: BA40]
|
[151] | |||
Valsartan
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[152] | |||
Propafenone
|
API Info |
Ventricular tachyarrhythmia [ICD-11: BC71]
|
[153] | |||
Benazepril
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[154] | |||
Carvedilol
|
API Info |
Congestive heart failure [ICD-11: BD10]
|
[155] | |||
Trandolapril
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[156] | |||
Amiodarone
|
API Info |
Ventricular tachyarrhythmia [ICD-11: BC71]
|
[157] | |||
Midodrine
|
API Info |
Orthostatic hypotension [ICD-11: BA21]
|
[158] | |||
Isosorbide dinitrate
|
API Info |
Angina pectoris [ICD-11: BA40]
|
[159] | |||
Isosorbide mononitrate
|
API Info |
Angina pectoris [ICD-11: BA40]
|
[160] | |||
Nitroglycerin
|
API Info |
Acute coronary syndrome [ICD-11: BA4Z]
|
[161] | |||
Dipyridamole
|
API Info |
Atherosclerosis [ICD-11: BA80]
|
[162] | |||
Acebutolol
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[163] | |||
Disopyramide
|
API Info |
Ventricular tachyarrhythmia [ICD-11: BC71]
|
[164] | |||
Bumetanide
|
API Info |
Congestive heart failure [ICD-11: BD10]
|
[165] | |||
Nicardipine
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[166] | |||
Bisoprolol
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[167] | |||
Nimodipine
|
API Info |
Cerebral vasospasm [ICD-11: BA85]
|
[168] | |||
Isradipine
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[169] | |||
Mexiletine
|
API Info |
Ventricular tachyarrhythmia [ICD-11: BC71]
|
[170] | |||
Phenoxybenzamine
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[171] | |||
Ambrisentan
|
API Info |
Pulmonary hypertension [ICD-11: BB01]
|
[172] | |||
Quinapril
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[173] | |||
ICD Disease Classification 12 | Respiratory system disease | Click to Show/Hide | ||||
Montelukast
|
API Info |
Asthma [ICD-11: CA23]
|
[174] | |||
Guaifenesin
|
API Info |
Asthma [ICD-11: CA23]
|
[175] | |||
Clarithromycin
|
API Info |
Pneumocystis pneumonia [ICD-11: CA40]
|
[176] | |||
Benzonatate
|
API Info |
Asthma [ICD-11: CA23]
|
[177] | |||
Chlorpheniramine
|
API Info |
Allergic rhinitis [ICD-11: CA08]
|
[178] | |||
Fexofenadine
|
API Info |
Allergic rhinitis [ICD-11: CA08]
|
[179] | |||
Promethazine
|
API Info |
Allergic rhinitis [ICD-11: CA08]
|
[180] | |||
Cefdinir
|
API Info |
Pneumocystis pneumonia [ICD-11: CA40]
|
[181] | |||
Desloratadine
|
API Info |
Allergic rhinitis [ICD-11: CA08]
|
[182] | |||
Cefadroxil
|
API Info |
Acute tonsillitis [ICD-11: CA03]
|
[183] | |||
Budesonide
|
API Info |
Allergic rhinitis [ICD-11: CA08]
|
[184] | |||
Cefpodoxime
|
API Info |
Bronchitis [ICD-11: CA20]
|
[185] | |||
Sirolimus
|
API Info |
Lymphangioleiomyomatosis [ICD-11: CB07]
|
[186] | |||
Theophylline
|
API Info |
Chronic obstructive pulmonary disease [ICD-11: CA22]
|
[187] | |||
ICD Disease Classification 13 | Digestive system disease | Click to Show/Hide | ||||
Doxycycline
|
API Info |
Periodontal disease [ICD-11: DA0C]
|
[188] | |||
Omeprazole
|
API Info |
Gastro-oesophageal reflux disease [ICD-11: DA22]
|
[189] | |||
Bisacodyl
|
API Info |
Irritable bowel syndrome [ICD-11: DD91]
|
[190] | |||
Meclizine
|
API Info |
Functional nausea/vomiting [ICD-11: DD90]
|
[191] | |||
Lansoprazole
|
API Info |
Duodenal ulcer [ICD-11: DA63]
|
[192] | |||
Simethicone
|
API Info |
Irritable bowel syndrome [ICD-11: DD91]
|
[193] | |||
Ranitidine
|
API Info |
Gastric ulcer [ICD-11: DA60]
|
[194] | |||
Esomeprazole
|
API Info |
Duodenal ulcer [ICD-11: DA63]
|
[195] | |||
Loperamide
|
API Info |
Irritable bowel syndrome [ICD-11: DD91]
|
[196] | |||
Bismuth subsalicylate
|
API Info |
Irritable bowel syndrome [ICD-11: DD91]
|
[197] | |||
Dicyclomine
|
API Info |
Irritable bowel syndrome [ICD-11: DD91]
|
[198] | |||
Mycophenolate mofetil
|
API Info |
Crohn disease [ICD-11: DD70]
|
[199] | |||
Tacrolimus
|
API Info |
Ulcerative colitis [ICD-11: DD71]
|
[200] | |||
Ursodeoxycholic acid
|
API Info |
Hepatic fibrosis/cirrhosis [ICD-11: DB93]
|
[201] | |||
Nizatidine
|
API Info |
Peptic ulcer [ICD-11: DA61]
|
[202] | |||
Mycophenolic acid
|
API Info |
Crohn disease [ICD-11: DD70]
|
[203] | |||
Famotidine
|
API Info |
Peptic ulcer [ICD-11: DA61]
|
[204] | |||
Trimethobenzamide
|
API Info |
Functional nausea/vomiting [ICD-11: DD90]
|
[205] | |||
Balsalazide
|
API Info |
Ulcerative colitis [ICD-11: DD71]
|
[206] | |||
Lubiprostone
|
API Info |
Irritable bowel syndrome [ICD-11: DD91]
|
[207] | |||
ICD Disease Classification 14 | Skin disease | Click to Show/Hide | ||||
Hydrochlorothiazide
|
API Info |
Luid retention [ICD-11: EF02]
|
[208] | |||
Clindamycin
|
API Info |
Acne vulgaris [ICD-11: ED80]
|
[209] | |||
Pseudoephedrine
|
API Info |
Erythema multiforme [ICD-11: EB12]
|
[210] | |||
Isotretinoin
|
API Info |
Acne vulgaris [ICD-11: ED80]
|
[211] | |||
Demeclocycline
|
API Info |
Acne vulgaris [ICD-11: ED80]
|
[212] | |||
Acitretin
|
API Info |
Psoriasis vulgaris [ICD-11: EA90]
|
[213] | |||
Tretinoin
|
API Info |
Acne vulgaris [ICD-11: ED80]
|
[214] | |||
ICD Disease Classification 15 | Musculoskeletal/connective-tissue disease | Click to Show/Hide | ||||
Naproxen
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[215] | |||
Indomethacin
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[216] | |||
Celecoxib
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[217] | |||
Diclofenac
|
API Info |
Knee osteoarthritis [ICD-11: FA01]
|
[218] | |||
Etodolac
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[219] | |||
Phenylephrine
|
API Info |
Juvenile rheumatoid arthritis [ICD-11: FA24]
|
[220] | |||
Meloxicam
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[221] | |||
Piroxicam
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[222] | |||
Cyclosporin A
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[223] | |||
Rifampicin
|
API Info |
Osteoporosis [ICD-11: FB83]
|
[224] | |||
Conjugated estrogen
|
API Info |
Osteoporosis [ICD-11: FB83]
|
[225] | |||
Dexamethasone
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[226] | |||
Metaxalone
|
API Info |
Myalgia [ICD-11: FB56]
|
[227] | |||
Fenoprofen
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[228] | |||
Colchicine
|
API Info |
Uncontrolled gout [ICD-11: FA25]
|
[229] | |||
Tolmetin
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[230] | |||
Ketorolac
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[231] | |||
Auranofin
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[232] | |||
ICD Disease Classification 16 | Genitourinary system disease | Click to Show/Hide | ||||
Ibuprofen
|
API Info |
Dysmenorrhea [ICD-11: GA34]
|
[233] | |||
Terazosin
|
API Info |
Prostatic hyperplasia [ICD-11: GA90]
|
[234] | |||
Finasteride
|
API Info |
Prostatic hyperplasia [ICD-11: GA90]
|
[235] | |||
Oxybutynin
|
API Info |
Overactive bladder [ICD-11: GC50]
|
[236] | |||
Erythromycin
|
API Info |
Pelvic inflammatory disease [ICD-11: GA05]
|
[237] | |||
Tamsulosin
|
API Info |
Prostatic hyperplasia [ICD-11: GA90]
|
[238] | |||
Nitrofurantoin
|
API Info |
Infectious cystitis [ICD-11: GC00]
|
[239] | |||
Bethanechol
|
API Info |
Urinary retention [ICD-11: GC01]
|
[240] | |||
Dutasteride
|
API Info |
Prostatic hyperplasia [ICD-11: GA90]
|
[241] | |||
Prazosin
|
API Info |
Prostatic hyperplasia [ICD-11: GA90]
|
[242] | |||
Progesterone
|
API Info |
Endometrial hyperplasia [ICD-11: GA16]
|
[243] | |||
Danazol
|
API Info |
Endometriosis [ICD-11: GA10]
|
[244] | |||
Methenamine
|
API Info |
Urinary tract infection [ICD-11: GC08]
|
[245] | |||
Phenazopyridine
|
API Info |
Infectious cystitis [ICD-11: GC00]
|
[246] | |||
Trospium
|
API Info |
Overactive bladder [ICD-11: GC50]
|
[247] | |||
Tiopronin
|
API Info |
Urinary calculus [ICD-11: GB70]
|
[248] | |||
ICD Disease Classification 18 | Pregnancy/childbirth/puerperium condition | Click to Show/Hide | ||||
Doxylamine
|
API Info |
Morning sickness [ICD-11: JA60]
|
[249] | |||
ICD Disease Classification 20 | Developmental anomaly | Click to Show/Hide | ||||
Estradiol
|
API Info |
Turner syndrome [ICD-11: LD50]
|
[250] | |||
Calcitriol
|
API Info |
Congenital alopecia [ICD-11: LC30]
|
[251] | |||
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG | ||||||
---|---|---|---|---|---|---|
G-protein coupled receptor (GPCR) | ||||||
DBT Name: Serotonin receptor 1A (5HT1A) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 19 uM (tested by experiment) | [252] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | 5HT1A_HUMAN | |||||
DBT Name: Dopamine D1 receptor (DRD1) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 29 uM (tested by experiment) | [252] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | DRD1_HUMAN | |||||
Oxidoreductase (ORase) | ||||||
DBT Name: Prostaglandin G/H synthase 2 (COX-2) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 26 uM (tested by experiment) | [252] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | PGH2_HUMAN | |||||
Hydrolase (HDase) | ||||||
DBT Name: Acetylcholinesterase (ACHE) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 > 10 uM (tested by experiment) | [252] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | ACES_HUMAN | |||||
DBT Name: Protein-tyrosine phosphatase 1B (PTPN1) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment (1) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 33000 nM (tested by experiment) | [253] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | PTN1_HUMAN | |||||
Experiment (2) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 410000 nM (tested by experiment) | [253] | ||||
Tested Species | Saccharomyces cerevisiae (Yeast) | |||||
UniProt ID | PTP1_YEAST | |||||
DBT Name: Phosphodiesterase 3A (PDE3A) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 17 uM (tested by experiment) | [252] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | PDE3A_HUMAN | |||||
Potential-driven transporter (PDT) | ||||||
DBT Name: Solute carrier SLCO2B1 (OATPB) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment (1) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | Inhibition ratio = 96.52 % (tested by experiment) | [254] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | SO2B1_HUMAN | |||||
Experiment (2) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | Ki = 2.59 uM (tested by experiment) | [254] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | SO2B1_HUMAN | |||||
Experiment (3) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | Ki = 4.7 uM (tested by experiment) | [252] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | SO2B1_HUMAN | |||||
Transmembrane channel/porin (TC/P) | ||||||
DBT Name: GABA(A) receptor alpha-1 (GABRA1) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 22 uM (tested by experiment) | [252] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | GBRA1_HUMAN | |||||
Nuclear receptor (NR) | ||||||
DBT Name: Androgen receptor (AR) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 28 uM (tested by experiment) | [252] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | ANDR_HUMAN | |||||
DBT Name: Estrogen receptor alpha (ESR1) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 15 uM (tested by experiment) | [252] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | ESR1_HUMAN | |||||
DBT Name: Progesterone receptor (PGR) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 30 uM (tested by experiment) | [252] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | PRGR_HUMAN | |||||
Other protein families (OPF) | ||||||
DBT Name: Thrombopoietin receptor (MPL) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | EC50 = 300 nM (estimated based on the structural similarity with CHEMBL123373 ) | [255] | ||||
Structural Similarity | Tanimoto coefficient = 0.925714286 | |||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | TPOR_HUMAN | |||||
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