Details of the Active Pharmaceutical Ingredient (API)

General Information of API (ID: D00303)
Name
Glipizide
Synonyms    Click to Show/Hide the Synonyms of This API
glipizide; 29094-61-9; Glucotrol; Glydiazinamide; Melizide; Glibenese; Glucozide; Glupizide; Sucrazide; Dipazide; Glupitel; Mindiab; Minidiab; Minodiab; Napizide; Ozidia; Glucotrol XL; Glibetin; Glucolip; Aldiab; Digrin; Glican; Glidiab; Glipid; Minidab; Gluco-Rite; Glipizida; Glipizidum; Glipizidum [INN-Latin]; Glipizida [INN-Spanish]; Metaglip; K 4024; CP 28720; K-4024; CP-28720; TK 1320; CP 28,720; UNII-X7WDT95N5C; N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-5-methylpyrazine-2-carboxamide; Glipizide (Glucotrol); MFCD00072159; CHEMBL1073; X7WDT95N5C; 1-Cyclohexyl-3-((p-(2-(5-methylpyrazinecarboxamido)ethyl)phenyl)sulfonyl)urea; CP-28,720; MLS000069386; CHEBI:5384; CP 28720;K 4024; NCGC00015462-07; SMR000058455; CAS-29094-61-9; 1-cyclohexyl-3-[[p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl]sulfonyl]urea; DSSTox_CID_20676; DSSTox_RID_79535; Urea, 1-cyclohexyl-3-((p-(2-(5-methylpyrazinecarboxamido)ethyl)phenyl)sulfonyl)-; DSSTox_GSID_40676; 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea; Glucotrol (TN); Glipizide (USP/INN); SR-01000000010; EINECS 249-427-6; BRN 0903495; Glipizide, solid; N-(4-[N-(cyclohexylcarbamoyl)sulfamoyl]phenethyl)-5-methylpyrazine-2-carboxamide; Glipizide [USAN:USP:INN:BAN]; glipizide/glucotrol; Glipizide,(S); Prestwick_242; Glipizide, 98+%; KS-1068; Metaglip (Salt/Mix); Lopac-G-117; Opera_ID_1908; Prestwick0_000131; Prestwick1_000131; Prestwick2_000131; Prestwick3_000131; CBiol_001788; Lopac0_000621; SCHEMBL17094; BSPBio_000202; BSPBio_001349; KBioGR_000069; KBioSS_000069; MLS001148176; BIDD:GT0476; SPBio_002141; BPBio1_000224; GTPL6821; DTXSID0040676; KBio2_000069; KBio2_002637; KBio2_005205; KBio3_000137; KBio3_000138; Bio1_000074; Bio1_000563; Bio1_001052; Bio2_000069; Bio2_000549; HMS1361D11; HMS1568K04; HMS1791D11; HMS1989D11; HMS2089C21; HMS2093J09; HMS2095K04; HMS2233N11; HMS3259K12; HMS3261N04; HMS3369L12; HMS3402D11; HMS3655G04; HMS3712K04; Pharmakon1600-01505433; ZINC537795; BCP09195; HY-B0254; Tox21_110156; Tox21_301834; Tox21_500621; ANW-41980; BBL028143; BDBM50012956; NSC759120; STK631952; AKOS005564405; N-[4-(3-Cyclohexylureidosulfonyl)phenethyl]-5-methyl-2-pyrazinecarboxamide; Tox21_110156_1; CCG-204710; DB01067; LP00621; MCULE-5142805548; NC00564; NSC-759120; SDCCGSBI-0050603.P003; 1-Cyclohexyl-3-{4-[2-(5-methylpyrazine-2-carboxamido)ethyl]phenylsulfonyl}urea; IDI1_033819; NCGC00015462-01; NCGC00015462-02; NCGC00015462-03; NCGC00015462-04; NCGC00015462-05; NCGC00015462-06; NCGC00015462-08; NCGC00015462-09; NCGC00015462-10; NCGC00015462-11; NCGC00015462-12; NCGC00015462-14; NCGC00015462-23; NCGC00016802-01; NCGC00023748-03; NCGC00023748-04; NCGC00023748-05; NCGC00023748-06; NCGC00023748-07; NCGC00255522-01; NCGC00261306-01; AC-15789; SBI-0050603.P002; AB0012143; EU-0100621; FT-0626714; FT-0659737; ST50826363; SW196549-3; D00335; 094G619; Q3108899; SR-01000000010-2; SR-01000000010-5; W-107005; BRD-K12219985-001-04-8; BRD-K12219985-001-15-4; Z1880962274; Glipizide, European Pharmacopoeia (EP) Reference Standard; Glipizide, United States Pharmacopeia (USP) Reference Standard; Glipizide, Pharmaceutical Secondary Standard; Certified Reference Material; 1-cyclohexyl-3-(4-(2-(2-methylpyrazine-5-carboxamido)ethyl)phenylsulfonyl)urea; 1-Cyclohexyl-3-{{p=[2-[5-methylpyrazine-carboxamido)-ethyl]phenyl}sulphonyl}urea; 1-Cyclohexyl-3-4-[2-(5-methylpyrazine-2-carboxamido)ethyl]phenylsulfonylurea; 172964-66-8
Clinical Status
Approved
Disease Indication Diabetes mellitus ICD-11: 5A10 [1]
PubChem CID
3478
Formula
C21H27N5O4S
Canonical SMILES
CC1=CN=C(C=N1)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
InChI
1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28)
InChIKey
ZJJXGWJIGJFDTL-UHFFFAOYSA-N
   Click to Show/Hide the Molecular Data (Structure/Property) of This API
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=3478"></iframe>
3D MOL 2D MOL
Physicochemical Properties Molecular Weight 445.5 Topological Polar Surface Area 139
XlogP 1.9 Complexity 697
Heavy Atom Count 31 Rotatable Bond Count 7
Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 6
Full List of Drug Formulations (DFMs) Containing This API
          Glipizide 5 mg tablet Click to Show/Hide the Full List of Formulation(s):        36 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Butylated hydroxytoluene; Fd&c red no. 40; Fd&c yellow no. 6; Glyceryl monostearate; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polysorbate 80; Silicon dioxide; Cellulose acetate; Ceteareth-8; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:2); Polyethylene glycols; Sodium starch glycolate type a corn
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company NuCare Pharmaceuticals; Par Pharmaceutical
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Allura red AC dye DIG Info Solute carrier SLCO2B1 (Ki = 4.7 uM) [2]
Butylated hydroxytoluene DIG Info Carbonic anhydrase II (Ki = 630 nM) [3]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Allura red AC dye DIG Info Solute carrier SLCO2B1 (Ki = 2.59 uM) [4]
Glyceryl monostearate DIG Info Prostate cancer LNCaP cells (IC50 > 100000 nM) [5]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Butyl alcohol; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Acetyltributyl citrate; Ammonia; Ferrosoferric oxide; Propylene glycol; Polyethylene glycol 400; Hydroxyethyl cellulose (2000 cps at 1%); Hydroxypropyl cellulose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Actavis Pharma; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Isopropyl alcohol DIG Info Lymphoma P388/ADR cells (IC50 = 0.22 uM) [8]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [6]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Butyl alcohol; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Acetyltributyl citrate; Ammonia; Ferrosoferric oxide; Propylene glycol; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hydroxypropyl cellulose (1200000 mw); Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycol, unspecified; Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Bryant Ranch Prepack; Unit Dose Services
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Isopropyl alcohol DIG Info Lymphoma P388/ADR cells (IC50 = 0.22 uM) [8]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 4 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Butyl alcohol; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Acetyltributyl citrate; Ammonia; Ferrosoferric oxide; Propylene glycol; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hydroxypropyl cellulose (type h); Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company A-S Medication Solutions; Aidarex Pharmaceuticals; Lake Eire Medical & Surgical Supply DBA Quality Care Products; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; Par Pharmaceutical; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Isopropyl alcohol DIG Info Lymphoma P388/ADR cells (IC50 = 0.22 uM) [8]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 5 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Butyl alcohol; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Acetyltributyl citrate; Ammonia; Ferrosoferric oxide; Propylene glycol; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hydroxypropyl cellulose; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Bryant Ranch Prepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Isopropyl alcohol DIG Info Lymphoma P388/ADR cells (IC50 = 0.22 uM) [8]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 6 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Butyl alcohol; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Acetyltributyl citrate; Ammonia; Ferrosoferric oxide; Propylene glycol; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hydroxypropyl cellulose (type h); Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Isopropyl alcohol DIG Info Lymphoma P388/ADR cells (IC50 = 0.22 uM) [8]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 7 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Acetyltributyl citrate; Ammonia; Ferrosoferric oxide; Propylene glycol; Polyethylene glycol 400; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hydroxypropyl cellulose (120000 mw); Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Aurobindo Pharma
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [6]
             Drug Formulation 8 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Silicon dioxide; Cellulose acetate; Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Mylan Pharamceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium stearyl fumarate DIG Info Leukemia K562 cells (IC50 = 20.2 ug.mL-1) [9]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 9 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company Actavis Pharma; Aphena Pharma Solutions-Tennessee; Bryant Ranch Prepack; Contract Pharmacal; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; RemedyRepack; State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 10 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Unit Dose Services
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 11 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Acetyltributyl citrate; Ferrosoferric oxide; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hydroxypropyl cellulose (type h); Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company American Health Packaging
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 12 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Acetyltributyl citrate; Hydroxyethyl cellulose (140 cps at 5%); Hydroxypropyl cellulose; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Actavis Elizabeth; Physicians Total Care
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 13 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Acetyltributyl citrate; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hydroxypropyl cellulose (type h); Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company NCS HealthCare of KY, Inc dba Vangard Labs
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 14 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company A-S Medication Solutions; Accord Healthcare; Aidarex Pharmaceuticals; Apotheca; NuCare Pharmaceuticals; RemedyRepack; State of Florida DOH Central Pharmacy; TYA Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 15 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Silicon dioxide; Microcrystalline cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Preferred Pharamaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 16 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 17 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn; Starch, potato
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 18 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Croscarmellose sodium; Cellulose, microcrystalline; Colloidal silicon dioxide; Starch, corn
                   Dosage Form Oral Tablet
                   Company Physicians Total Care; Rebel Distributors; RemedyRepack; Stat Rx USA
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
             Drug Formulation 19 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company IVAX Pharmaceuticals; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 20 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn; Starch, potato
                   Dosage Form Oral Tablet
                   Company DirectRX; Sun Pharmaceutical Industries
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 21 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company Aphena Pharma Solutions-Tennessee; Cardinal Health; McKesson; Mylan Pharamceuticals; NCS HealthCare of KY, Inc dba Vangard Labs
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 22 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Silicon dioxide; Microcrystalline cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Cardinal Health; Mylan Pharamceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 23 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 24 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose, unspecified form; Silicon dioxide; Microcrystalline cellulose
                   Dosage Form Oral Tablet
                   Company Roerig
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 25 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Croscarmellose sodium; Cellulose, microcrystalline; Colloidal silicon dioxide; Starch, corn
                   Dosage Form Oral Tablet
                   Company Blenheim Phamacal
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
             Drug Formulation 26 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company DirectRX
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 27 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Polyethylene glycol 3350; Cellulose acetate; Hypromellose 2910 (15 mpa.s); Hypromellose 2910 (5 mpa.s); Polyethylene oxide 200000; Polyethylene oxide 7000000; Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Rising Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Polyethylene glycol 3350 DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
             Drug Formulation 28 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company Aphena Pharma Solutions-Tennessee; Avera McKennan Hospital; Clinical Solutions Wholesale; Contract Pharmacal; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Legacy Pharmaceutical; Preferred Pharamaceuticals; Proficient Rx; RemedyRepack; Sandoz; Upsher-Smith Laboratories
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 29 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company Major Pharmaceuticals; State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 30 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 31 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company RedPharm
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 32 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Sodium chloride; Hypromellose; Cellulose acetate; Polyethylene glycol
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Hypromellose DIG Info Cytochrome P450 3A5 (IC50 = 19.4 uM) [10]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 33 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Silicon dioxide; Sodium starch glycolate type a potato
                   Dosage Form Oral Tablet
                   Company A-S Medication Solutions; Aidarex Pharmaceuticals; Apotex; Blenheim Phamacal; Contract Pharmacal; Golden State Medical Supply; Major Pharmaceuticals; NCS HealthCare of KY, Inc dba Vangard Labs; Preferred Pharamaceuticals; RemedyRepack; St Marys Medical Park Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 34 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Sodium chloride; Cellulose acetate; Hypromelloses; Polyethylene glycol
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Physicians Total Care
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 35 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Sodium chloride; Cellulose acetate; Hypromellose, unspecified; Polyethylene glycol, unspecified
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Greenstone; Roerig
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 36 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Sodium chloride; Cellulose acetate; Hypromelloses; Polyethylene glycols
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company St Marys Medical Park Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
          Glipizide 10 mg tablet Click to Show/Hide the Full List of Formulation(s):        35 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Butylated hydroxytoluene; Glyceryl monostearate; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polysorbate 80; Silicon dioxide; Cellulose acetate; Ceteareth-8; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:2); Polyethylene glycols; Sodium starch glycolate type a corn
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company NuCare Pharmaceuticals; Par Pharmaceutical; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Butylated hydroxytoluene DIG Info Carbonic anhydrase II (Ki = 630 nM) [3]
Glyceryl monostearate DIG Info Prostate cancer LNCaP cells (IC50 > 100000 nM) [5]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Acetyltributyl citrate; Ammonia; Ferrosoferric oxide; Propylene glycol; Polyethylene glycol 400; Hydroxyethyl cellulose (2000 cps at 1%); Hydroxypropyl cellulose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Actavis Pharma; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Isopropyl alcohol DIG Info Lymphoma P388/ADR cells (IC50 = 0.22 uM) [8]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [6]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Silicon dioxide; Cellulose acetate; Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Mylan Pharamceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium stearyl fumarate DIG Info Leukemia K562 cells (IC50 = 20.2 ug.mL-1) [9]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 4 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Acetyltributyl citrate; Ammonia; Ferrosoferric oxide; Propylene glycol; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hydroxypropyl cellulose (type h); Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Isopropyl alcohol DIG Info Lymphoma P388/ADR cells (IC50 = 0.22 uM) [8]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 5 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Acetyltributyl citrate; Ammonia; Ferrosoferric oxide; Propylene glycol; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hydroxypropyl cellulose (1200000 mw); Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycol, unspecified; Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Bryant Ranch Prepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Isopropyl alcohol DIG Info Lymphoma P388/ADR cells (IC50 = 0.22 uM) [8]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 6 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Acetyltributyl citrate; Ammonia; Ferrosoferric oxide; Propylene glycol; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hydroxypropyl cellulose (type h); Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company A-S Medication Solutions; Aidarex Pharmaceuticals; Avera McKennan Hospital; Carilion Materials Management; DirectRX; Lake Eire Medical & Surgical Supply DBA Quality Care Products; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; Par Pharmaceutical
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Isopropyl alcohol DIG Info Lymphoma P388/ADR cells (IC50 = 0.22 uM) [8]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 7 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company Actavis Pharma; Bryant Ranch Prepack; Clinical Solutions Wholesale; Northwind Pharmaceuticals; NuCare Pharmaceuticals; Proficient Rx; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 8 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company A-S Medication Solutions; Unit Dose Services
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 9 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company A-S Medication Solutions; Accord Healthcare; Aidarex Pharmaceuticals; Apotheca; NuCare Pharmaceuticals; RemedyRepack; State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 10 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Silicon dioxide; Microcrystalline cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Preferred Pharamaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 11 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 12 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn; Starch, potato
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 13 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Croscarmellose sodium; Cellulose, microcrystalline; Colloidal silicon dioxide; Starch, corn
                   Dosage Form Oral Tablet
                   Company Blenheim Phamacal; H. J. Harkins Company; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Physicians Total Care; Rebel Distributors; Stat Rx USA
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
             Drug Formulation 14 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company MedVantx
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 15 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn; Starch, potato
                   Dosage Form Oral Tablet
                   Company Sun Pharmaceutical Industries
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 16 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company Cardinal Health; McKesson; Mylan Pharamceuticals; NCS HealthCare of KY, Inc dba Vangard Labs
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 17 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Silicon dioxide; Microcrystalline cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Cardinal Health; Mylan Pharamceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 18 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 19 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose, unspecified form; Silicon dioxide; Microcrystalline cellulose
                   Dosage Form Oral Tablet
                   Company PD-Rx Pharmaceuticals; Roerig
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 20 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Anhydrous lactose; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company RedPharm
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 21 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Acetyltributyl citrate; Ammonia; Ferrosoferric oxide; Propylene glycol; Polyethylene glycol 400; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hydroxypropyl cellulose (120000 mw); Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Aurobindo Pharma
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [6]
             Drug Formulation 22 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Polyethylene glycol 3350; Cellulose acetate; Hypromellose 2910 (15 mpa.s); Hypromellose 2910 (5 mpa.s); Polyethylene oxide 200000; Polyethylene oxide 7000000; Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Rising Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Polyethylene glycol 3350 DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
             Drug Formulation 23 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company Aphena Pharma Solutions-Tennessee; Clinical Solutions Wholesale; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Legacy Pharmaceutical; PD-Rx Pharmaceuticals; Preferred Pharamaceuticals; RemedyRepack; Sandoz; Upsher-Smith Laboratories
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 24 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company Major Pharmaceuticals; RemedyRepack; State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 25 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 26 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Bryant Ranch Prepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 27 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Sodium chloride; Hypromellose; Cellulose acetate; Polyethylene glycol
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Hypromellose DIG Info Cytochrome P450 3A5 (IC50 = 19.4 uM) [10]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 28 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Silicon dioxide; Sodium starch glycolate type a potato
                   Dosage Form Oral Tablet
                   Company A-S Medication Solutions; Aidarex Pharmaceuticals; Apotex; Blenheim Phamacal; DirectRX; Golden State Medical Supply; NCS HealthCare of KY, Inc dba Vangard Labs; NuCare Pharmaceuticals; Preferred Pharamaceuticals; RemedyRepack; St Marys Medical Park Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 29 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Silicon dioxide; Sodium starch glycolate type a potato
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 30 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Acetyltributyl citrate; Ferrosoferric oxide; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hydroxypropyl cellulose (type h); Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company American Health Packaging
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 31 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Sodium chloride; Cellulose acetate; Hypromelloses; Polyethylene glycol
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Physicians Total Care
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 32 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Sodium chloride; Cellulose acetate; Hypromellose, unspecified; Polyethylene glycol, unspecified
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Greenstone; Roerig
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 33 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Sodium chloride; Cellulose acetate; Hypromelloses; Polyethylene glycols
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 34 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Acetyltributyl citrate; Hydroxyethyl cellulose (140 cps at 5%); Hydroxypropyl cellulose; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Actavis Elizabeth; Physicians Total Care; State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 35 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Acetyltributyl citrate; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hydroxypropyl cellulose (type h); Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company NCS HealthCare of KY, Inc dba Vangard Labs
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
          Glipizide 2.5 mg tablet Click to Show/Hide the Full List of Formulation(s):        12 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Butyl alcohol; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Acetyltributyl citrate; Ammonia; Ferrosoferric oxide; Propylene glycol; Polyethylene glycol 400; Hydroxyethyl cellulose (2000 cps at 1%); Hydroxypropyl cellulose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Actavis Pharma
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Isopropyl alcohol DIG Info Lymphoma P388/ADR cells (IC50 = 0.22 uM) [8]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [6]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 3350; Cellulose acetate; Hypromellose 2910 (15 mpa.s); Hypromellose 2910 (5 mpa.s); Polyethylene oxide 200000; Polyethylene oxide 7000000; Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Rising Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Polyethylene glycol 3350 DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Butyl alcohol; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Acetyltributyl citrate; Ammonia; Ferrosoferric oxide; Propylene glycol; Hydroxyethyl cellulose (2000 cps at 1%); Hydroxypropyl cellulose; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycol; Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Rebel Distributors
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Isopropyl alcohol DIG Info Lymphoma P388/ADR cells (IC50 = 0.22 uM) [8]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 4 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Butyl alcohol; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Acetyltributyl citrate; Ammonia; Ferrosoferric oxide; Propylene glycol; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hydroxypropyl cellulose (1200000 mw); Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycol, unspecified; Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Bryant Ranch Prepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Isopropyl alcohol DIG Info Lymphoma P388/ADR cells (IC50 = 0.22 uM) [8]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 5 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Butyl alcohol; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Acetyltributyl citrate; Ammonia; Ferrosoferric oxide; Propylene glycol; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hydroxypropyl cellulose (type h); Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Avera McKennan Hospital; NuCare Pharmaceuticals; Unit Dose Services
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Isopropyl alcohol DIG Info Lymphoma P388/ADR cells (IC50 = 0.22 uM) [8]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 6 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Butyl alcohol; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Acetyltributyl citrate; Ammonia; Ferrosoferric oxide; Propylene glycol; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hydroxypropyl cellulose (type h); Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Isopropyl alcohol DIG Info Lymphoma P388/ADR cells (IC50 = 0.22 uM) [8]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 7 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Fd&c blue no. 2; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Silicon dioxide; Cellulose acetate; Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Mylan Pharamceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [2]
Sodium stearyl fumarate DIG Info Leukemia K562 cells (IC50 = 20.2 ug.mL-1) [9]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 8 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Acetyltributyl citrate; Ammonia; Ferrosoferric oxide; Propylene glycol; Polyethylene glycol 400; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hydroxypropyl cellulose (120000 mw); Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Aurobindo Pharma
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [6]
             Drug Formulation 9 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Acetyltributyl citrate; Ferrosoferric oxide; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hydroxypropyl cellulose (type h); Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company American Health Packaging
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 10 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Acetyltributyl citrate; Hydroxyethyl cellulose (140 cps at 5%); Hydroxypropyl cellulose; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Actavis Elizabeth; Physicians Total Care
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 11 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Sodium chloride; Cellulose acetate; Hypromelloses; Polyethylene glycol
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Physicians Total Care
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 12 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Sodium chloride; Cellulose acetate; Hypromellose, unspecified; Polyethylene glycol, unspecified
                   Dosage Form 24 HR Extended Release Oral Tablet
                   Company Greenstone; Roerig
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
References
1 FDA label for approved glipizide from the official website of the U.S. Food and Drug Administration.
2 The activities of drug inactive ingredients on biological targets. Science. 2020 Jul 24;369(6502):403-413.
3 Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols. Bioorg Med Chem. 2009 Apr 15; 17(8):3207-11.
4 Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16009-16018.
5 Lignanamides and nonalkaloidal components of Hyoscyamus niger seeds. J Nat Prod. 2002 Feb; 65(2):206-9.
6 Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration. Eur J Pharm Biopharm. 2008 Sep;70(1):279-88.
7 Effects of commonly used excipients on the expression of CYP3A4 in colon and liver cells. Pharm Res. 2010 Aug;27(8):1703-12.
8 Synthesis and evaluation of dihydropyrroloquinolines that selectively antagonize P-glycoprotein. J Med Chem. 2004 Mar 11; 47(6):1413-22.
9 Synthesis and evaluation of (-)-Massoialactone and analogues as potential anticancer and anti-inflammatory agents. Eur J Med Chem. 2014 Apr 9; 76:291-300.
10 Mediation of in vitro cytochrome p450 activity by common pharmaceutical excipients. Mol Pharm. 2013 Jul 1;10(7):2739-48.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.