Details of the Drug Formulation (DFM)
General Information of DFM (ID: F00481) | |||||
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Name |
Acetylcysteine 500 mg tablet
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Company |
Arbor Pharmaceuticals
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Active Pharmaceutical Ingredient (API) | Acetylcysteine | API Info click to show the detail info of this API | |||
Pterygium | ICD-11: 9A61 | Approved | |||
Drug Inactive Ingredient (DIGs) | |||||
DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
E0NN4I | DIG Info | Dextrin | Binding agent ... | ||
E0FY2S | DIG Info | Edetate disodium | Complexing agent | ||
E0G1YW | DIG Info | Sodium bicarbonate | Alkalizing agent ... | ||
E04KTP | DIG Info | Sucralose | Flavoring agent | ||
Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
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Lyase/isomerase/ligase (L/I/G) | ||||||
DBT Name: Carbonic anhydrase II (CA2) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Interacting DIG | Sucralose | |||||
Biological Activity | Ki = 300 nM (tested by experiment) | [1] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | CAH2_HUMAN | |||||
DBT Name: Carbonic anhydrase IX (CA9) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Interacting DIG | Sucralose | |||||
Biological Activity | Ki = 2200 nM (tested by experiment) | [1] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | CAH9_HUMAN | |||||
Cell line (CELL) | ||||||
DBT Name: Colon cancer Caco-2 cells (Caco-2) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Interacting DIG | Dextrin | |||||
Biological Activity | Inhibition ratio > 55 % (tested by experiment) | [2] | ||||
Tested Species | Homo sapiens (Human) | |||||
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