Details of the Drug Inactive Ingredient (DIG)

General Information of DIG (ID: E0G1YW)
DIG Name	Sodium bicarbonate
Synonyms	Click to Show/Hide the Synonyms of This DIG SODIUM BICARBONATE; 144-55-8; Sodium hydrogen carbonate; Sodium hydrogencarbonate; Baking soda; Carbonic acid monosodium salt; Sodium acid carbonate; Bicarbonate of soda; Sodium hydrocarbonate; Meylon; Acidosan; Neut; Natriumhydrogenkarbonat; NaHCO3; Monosodium carbonate; Jusonin; Soludal; Soda Mint; Soda (van); Carbonic acid sodium salt (1:1); Sodium bicarbonate (1:1); Monosodium hydrogen carbonate; MFCD00003528; Carbonic acid, monosodium salt; UNII-8MDF5V39QO; sodium hydrogencarbonat; 8MDF5V39QO; E500; CHEBI:32139; Natron; Col-evac; Sel De vichy; Natrium bicarbonicum; Soda Ash; Natrii hydrogencarbonas; E 500; E-500; Natrium hydrogencarbonicum; sodium hydrogen-carbonate; Caswell No. 747; Sodium carbonate (Na(HCO3)); Sodium bicarbonate, 99+%, for HPLC; Sodium bicarbonate, 99+%, extra pure; Sodium bicarbonate, 99.5%, for analysis; Sodium bicarbonate in plastic container; Meylon (TN); Sodium bicarbonate, 99.7+%, ACS reagent; CCRIS 3064; HSDB 697; Sodium bicarbonate, 99.5%, for biochemistry; Neut (TN); NSC-134031; EINECS 205-633-8; Sodium bicarbonate solution; EPA Pesticide Chemical Code 073505; NSC 134031; Sodium bicarbonate [USP:JAN]; sodium bicabonate; sodium bicarbonat; bicarbonate sodium; sodiumbi-carbonate; sodium bi-carbonate; sodium bicarbonate-; Sodium bi carbonate; natriumhydrogencarbonat; CHNaO3; sodium hydrogencabonate; sodiumhydrogen carbonate; PubChem23592; sodium hydrogen cabonate; ACMC-20ajp0; hydrogen carbonate sodium; Sodium bicarbonate, USP; sodium hyd-rogencarbonate; sodium-hydrogen-carbonate; SODIUM BICARBONIATE; EC 205-633-8; CHEMBL1353; INS NO.500(II); DTXSID9021269; INS-500(II); Sodium bicarbonate (JP17/USP); sodium hydrogen carbonate solution; AMY40219; E-500(II); Sodium bicarbonate -40-+140 mesh; Sodium bicarbonate, Biochemical Grade; AKOS015836321; AKOS015951222; Sodium hydrogen carbonate, Puratronic?; DB01390; Sodium bicarbonate A.C.S. reagent grade; S304; Bicarbonate, 1M buffer solution, pH 8.0; Bicarbonate, 1M buffer solution, pH 8.5; B7292; FT-0645108; S0561; C12603; D01203; 3-Phenyl-2-thioxotetrahydropyrimidin-4(1H)-one; Sodium bicarbonate, 1M buffer solution, pH 8.0; Sodium bicarbonate, 1M buffer solution, pH 9.0; Q179731; Sodium bicarbonate, 1M buffer solution, pH 10.0; Sodium bicarbonate, HPLC, Meets ACS Specifications; Sodium bicarbonate 5% w/v solution in water (+/- 0.3%); Saturated aqueous Sodium bicarbonate solution (~9.6% wt/wt/)
DIG Function	Alkalizing agent; Diluent
PubChem CID	516892
Formula	CHNaO3
Canonical SMILES	C(=O)(O)[O-].[Na+]
InChI	1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1
InChIKey	UIIMBOGNXHQVGW-UHFFFAOYSA-M
	Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure	<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=516892"></iframe>
Structure	3D MOL is not available		2D MOL
Physicochemical Properties	Molecular Weight	84.007	Topological Polar Surface Area	60.4
	XlogP	N.A.	Complexity	33.9
	Heavy Atom Count	5	Rotatable Bond Count	0
	Hydrogen Bond Donor Count	1	Hydrogen Bond Acceptor Count	3

Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG
ICD Disease Classification 01		Infectious/parasitic disease	Click to Show/Hide
Hydroxychloroquine	API Info	Malaria [ICD-11: 1F40]		[1]
Delafloxacin	API Info	Methicillin-resistant staphylococcus infection [ICD-11: 1D01]		[2]
ICD Disease Classification 02		Benign/in-situ/malignant neoplasm	Click to Show/Hide
Prednisolone	API Info	Multiple myeloma [ICD-11: 2A83]		[3]
Exemestane	API Info	Breast cancer [ICD-11: 2C60]		[4]
ICD Disease Classification 04		Immune system disease	Click to Show/Hide
Cetirizine	API Info	Allergy [ICD-11: 4A80]		[5]
ICD Disease Classification 05		Endocrine/nutritional/metabolic disease	Click to Show/Hide
Levothroid	API Info	Hypothyroidism [ICD-11: 5A00]		[6]
Atorvastatin	API Info	Hyperlipidaemia [ICD-11: 5C8Z]		[7]
Pravastatin	API Info	Dyslipidaemia [ICD-11: 5C81]		[8]
Rosuvastatin	API Info	Hypertriglyceridaemia [ICD-11: 5C80]		[9]
Fluvastatin	API Info	Hypertriglyceridaemia [ICD-11: 5C80]		[10]
ICD Disease Classification 06		Mental/behavioural/neurodevelopmental disorder	Click to Show/Hide
Bupropion	API Info	Nicotine dependence [ICD-11: 6C4A]		[11]
Venlafaxine	API Info	Major depressive disorder [ICD-11: 6A70]		[12]
Mirtazapine	API Info	Major depressive disorder [ICD-11: 6A70]		[13]
Clozapine	API Info	Schizophrenia [ICD-11: 6A20]		[14]
Acamprosate	API Info	Alcohol dependence [ICD-11: 6C40]		[15]
Iloperidone	API Info	Schizophrenia [ICD-11: 6A20]		[16]
ICD Disease Classification 07		Sleep-wake disorder	Click to Show/Hide
Zolpidem	API Info	Insomnia [ICD-11: 7A00]		[17]
ICD Disease Classification 08		Nervous system disease	Click to Show/Hide
Acetaminophen	API Info	Anaesthesia [ICD-11: 8E22]		[18]
Valproic acid	API Info	Epilepsy [ICD-11: 8A60]		[19]
Zolmitriptan	API Info	Migraine [ICD-11: 8A80]		[20]
Fentanyl	API Info	Anaesthesia [ICD-11: 8E22]		[21]
Sumatriptan	API Info	Migraine [ICD-11: 8A80]		[22]
Benzocaine	API Info	Anaesthesia [ICD-11: 8E22]		[23]
ICD Disease Classification 09		Visual system disease	Click to Show/Hide
Acetylcysteine	API Info	Pterygium [ICD-11: 9A61]		[24]
ICD Disease Classification 11		Circulatory system disease	Click to Show/Hide
Aspirin	API Info	Myocardial infarction [ICD-11: BA41]		[25]
Enalapril	API Info	Essential hypertension [ICD-11: BA00]		[26]
Moexipril	API Info	Essential hypertension [ICD-11: BA00]		[27]
ICD Disease Classification 12		Respiratory system disease	Click to Show/Hide
Fexofenadine	API Info	Allergic rhinitis [ICD-11: CA08]		[28]
Loratadine	API Info	Allergic rhinitis [ICD-11: CA08]		[29]
ICD Disease Classification 13		Digestive system disease	Click to Show/Hide
Bisacodyl	API Info	Irritable bowel syndrome [ICD-11: DD91]		[30]
Lansoprazole	API Info	Duodenal ulcer [ICD-11: DA63]		[31]
Ranitidine	API Info	Gastric ulcer [ICD-11: DA60]		[32]
Mycophenolic acid	API Info	Crohn disease [ICD-11: DD70]		[33]
ICD Disease Classification 15		Musculoskeletal/connective-tissue disease	Click to Show/Hide
Diclofenac	API Info	Knee osteoarthritis [ICD-11: FA01]		[34]
Meloxicam	API Info	Rheumatoid arthritis [ICD-11: FA20]		[35]
Alendronic acid	API Info	Osteoporosis [ICD-11: FB83]		[36]
ICD Disease Classification 16		Genitourinary system disease	Click to Show/Hide
Oxybutynin	API Info	Overactive bladder [ICD-11: GC50]		[37]
ICD Disease Classification 20		Developmental anomaly	Click to Show/Hide
Estradiol	API Info	Turner syndrome [ICD-11: LD50]		[38]

References
1	FDA label for approved hydroxychloroquine from the official website of the U.S. Food and Drug Administration.
2	FDA label for approved delafloxacin from the official website of the U.S. Food and Drug Administration.
3	FDA label for approved prednisolone from the official website of the U.S. Food and Drug Administration.
4	FDA label for approved exemestane from the official website of the U.S. Food and Drug Administration.
5	FDA label for approved cetirizine from the official website of the U.S. Food and Drug Administration.
6	FDA label for approved levothroid from the official website of the U.S. Food and Drug Administration.
7	FDA label for approved atorvastatin from the official website of the U.S. Food and Drug Administration.
8	FDA label for approved pravastatin from the official website of the U.S. Food and Drug Administration.
9	FDA label for approved rosuvastatin from the official website of the U.S. Food and Drug Administration.
10	FDA label for approved fluvastatin from the official website of the U.S. Food and Drug Administration.
11	FDA label for approved bupropion from the official website of the U.S. Food and Drug Administration.
12	FDA label for approved venlafaxine from the official website of the U.S. Food and Drug Administration.
13	FDA label for approved mirtazapine from the official website of the U.S. Food and Drug Administration.
14	FDA label for approved clozapine from the official website of the U.S. Food and Drug Administration.
15	FDA label for approved acamprosate from the official website of the U.S. Food and Drug Administration.
16	FDA label for approved iloperidone from the official website of the U.S. Food and Drug Administration.
17	FDA label for approved zolpidem from the official website of the U.S. Food and Drug Administration.
18	FDA label for approved acetaminophen from the official website of the U.S. Food and Drug Administration.
19	FDA label for approved valproic acid from the official website of the U.S. Food and Drug Administration.
20	FDA label for approved zolmitriptan from the official website of the U.S. Food and Drug Administration.
21	FDA label for approved fentanyl from the official website of the U.S. Food and Drug Administration.
22	FDA label for approved sumatriptan from the official website of the U.S. Food and Drug Administration.
23	Benzocaine.
24	FDA label for approved acetylcysteine from the official website of the U.S. Food and Drug Administration.
25	FDA label for approved aspirin from the official website of the U.S. Food and Drug Administration.
26	FDA label for approved enalapril from the official website of the U.S. Food and Drug Administration.
27	FDA label for approved moexipril from the official website of the U.S. Food and Drug Administration.
28	FDA label for approved fexofenadine from the official website of the U.S. Food and Drug Administration.
29	FDA label for approved loratadine from the official website of the U.S. Food and Drug Administration.
30	FDA label for approved bisacodyl from the official website of the U.S. Food and Drug Administration.
31	FDA label for approved lansoprazole from the official website of the U.S. Food and Drug Administration.
32	FDA label for approved ranitidine from the official website of the U.S. Food and Drug Administration.
33	FDA label for approved mycophenolic acid from the official website of the U.S. Food and Drug Administration.
34	FDA label for approved diclofenac from the official website of the U.S. Food and Drug Administration.
35	FDA label for approved meloxicam from the official website of the U.S. Food and Drug Administration.
36	FDA label for approved alendronic acid from the official website of the U.S. Food and Drug Administration.
37	FDA label for approved oxybutynin from the official website of the U.S. Food and Drug Administration.
38	FDA label for approved estradiol from the official website of the U.S. Food and Drug Administration.

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