Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00447) | |||||
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| Name |
Morphine
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| Synonyms |
Click to Show/Hide the Synonyms of This API
morphine; Morphia; Morphinum; Morphium; Morphin; (-)-Morphine; Morphina; DepoDur; Duromorph; Meconium; Morphinism; Moscontin; Ospalivina; 57-27-2; MS Contin; l-Morphine; Dulcontin; Morfina; Roxanol; MORPHINE SULFATE; Infumorph; Dreamer; Morpho; Avinza; Kadian; Cube juice; Hard stuff; Statex SR; Ms Emma; Morphin [German]; Morfina [Italian]; Duramorph; Morphina [Italian]; M-Eslon; Morphine [BAN]; Nepenthe; CCRIS 5762; HSDB 2134; (5R,6S,9R,13S,14R)-4,5-Epoxy-N-methyl-7-morphinen-3,6-diol; UNII-76I7G6D29C; CHEBI:17303; CHEMBL70; (5alpha,6alpha)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol; 4,5alpha-Epoxy-17-methyl-7-morphinen-3,6alpha-diol; 7,8-Didehydro-4,5-epoxy-17-methyl-morphinan-3,6-diol; Morphine Anhydrate; 76I7G6D29C; Morphine (BAN); (5alpha,6alpha)-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol; Morphinan-3,6-alpha-diol, 7,8-didehydro-4,5-alpha-epoxy-17-methyl-; Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-, (5alpha,6alpha)-; methyl[?]diol; Aguettant; Dinamorf; Sevredol; Dimorf; (5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol; D-(-)-Morphine; EINECS 200-320-2; Dolcontin; Oramorph; DEA No. 9300; (Morphine); Anhydrous morphine; N02AA01; Substitol (TN); (-)-(etorphine); (-)Morphine sulfate; Morfina Dosa (TN); NSC11441; Epitope ID:116646; SCHEMBL2997; BIDD:GT0147; GTPL1627; IDS-NM-009; DTXSID9023336; Morphine 0.1 mg/ml in Methanol; Morphine 1.0 mg/ml in Methanol; ZINC3812983; BDBM50000092; AKOS015966554; DB00295; C01516; D08233; Hydromorphone hydrochloride impurity, morphine-; Q81225; 7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol; UNII-1M5VY6ITRT component BQJCRHHNABKAKU-KBQPJGBKSA-N; 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol; 7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine); (5alpha,6beta)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol; 3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester; 6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine; (-)(5.alpha.,6.alpha.)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol; Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5..alpha.,6.alpha.)-
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| Clinical Status |
Approved
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| Disease Indication | Anaesthesia | ICD-11: 8E22 | [1] | ||
| PubChem CID | |||||
| Formula |
C17H19NO3
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| Canonical SMILES |
CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3[C@H](C=C4)O
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| InChI |
1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1
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| InChIKey |
BQJCRHHNABKAKU-KBQPJGBKSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=5288826"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 285.34 | Topological Polar Surface Area | 52.9 | |
| XlogP | 0.8 | Complexity | 494 | ||
| Heavy Atom Count | 21 | Rotatable Bond Count | 0 | ||
| Hydrogen Bond Donor Count | 2 | Hydrogen Bond Acceptor Count | 4 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
|---|---|---|---|---|---|---|
| Morphine 15 mg tablet | Click to Show/Hide the Full List of Formulation(s): 34 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Mannitol; Ammonia; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Polysorbate 80; Silicon dioxide; Sodium alginate; Alginic acid; Cellulose, microcrystalline; Ethyl acrylate and methyl methacrylate copolymer (2:1 600000 mw); Ethyl acrylate and methyl methacrylate copolymer (2:1 750000 mw); Hypromelloses; Polyethylene glycols; Shellac; Xanthan gum
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| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Inspirion Delivery Sciences | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Stearic acid; Lactose monohydrate; Butylated hydroxytoluene; Fd&c blue no. 2; Magnesium stearate; Butylated hydroxyanisole; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hypromelloses
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| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [8] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Drug Formulation 3 |
DFM Info
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Stearic acid; Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 4000; Silicon dioxide; Hypromelloses; Povidones
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Silicon dioxide; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hydroxypropyl cellulose, low substituted; Hypromellose 2208 (100 mpa.s)
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Novel Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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Stearic acid; Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Hypromellose; Polysorbate 80; Aluminum oxide; Carnauba wax; Polyethylene glycol
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Ethex Corporation | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 3350; Silicon dioxide; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hydroxypropyl cellulose, low substituted; Hypromellose 2208 (100 mpa.s); Polyvinyl alcohol, unspecified
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Hypromelloses; Polyethylene glycols
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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|
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Stearic acid; Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Hypromellose, unspecified; Polyethylene glycol, unspecified
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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Stearic acid; Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Hypromelloses; Polyethylene glycols
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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|
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Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Hypromellose; Silicon dioxide
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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Lactose; Cetostearyl alcohol; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Hypromellose; Polysorbate 80; Polyethylene glycol; Powdered cellulose
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 12 |
DFM Info
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Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Silicon dioxide; Hypromellose 2208 (15000 mpa.s)
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | American Health Packaging; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 13 |
DFM Info
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Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Silicon dioxide; Hypromellose 2910 (15 mpa.s)
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Qualitest Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 14 |
DFM Info
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Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Silicon dioxide; Hypromelloses
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 15 |
DFM Info
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Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Silicon dioxide; Hypromelloses
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 16 |
DFM Info
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Lactose; Cetostearyl alcohol; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hydroxyethyl cellulose (140 cps at 5%); Hypromelloses; Polyethylene glycol
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | H. J. Harkins Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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Lactose; Cetostearyl alcohol; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hydroxyethyl cellulose (140 cps at 5%); Hypromelloses; Polyethylene glycols
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | DirectRX; Lake Eire Medical & Surgical Supply DBA Quality Care Products; PD-Rx Pharmaceuticals; Rhodes Pharmaceuticals; Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 18 |
DFM Info
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Lactose, unspecified form; Cetostearyl alcohol; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hydroxyethyl cellulose (140 mpa.s at 5%); Hypromellose, unspecified; Polyethylene glycol, unspecified
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 19 |
DFM Info
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Lactose; Cetostearyl alcohol; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hydroxyethyl cellulose (140 mpa.s at 5%); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose, unspecified form; Cetostearyl alcohol; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hydroxyethyl cellulose (140 mpa.s at 5%); Hypromelloses; Polyethylene glycols
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose, unspecified form; Cetostearyl alcohol; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hypromellose, unspecified; Polyethylene glycol, unspecified; Powdered cellulose
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 22 |
DFM Info
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Lactose; Cetostearyl alcohol; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hypromelloses; Polyethylene glycol; Powdered cellulose
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 23 |
DFM Info
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Lactose; Cetostearyl alcohol; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hydroxyethyl cellulose (140 cps at 5%); Hypromelloses; Polyethylene glycols
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose; Cetostearyl alcohol; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hydroxyethyl cellulose (140 cps at 5%); Hypromelloses; Polyethylene glycol
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|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 25 |
DFM Info
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Lactose, unspecified form; Cetostearyl alcohol; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hydroxyethyl cellulose (140 mpa.s at 5%); Hypromellose, unspecified; Polyethylene glycol, unspecified
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Rhodes Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Lactose; Cetostearyl alcohol; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hydroxyethyl cellulose (140 mpa.s at 5%); Hypromelloses; Polyethylene glycols
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Purdue Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 27 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose 2208 (15000 mpa.s); Polydextrose; Polyethylene glycol
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|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose 2208 (15000 mpa.s); Polydextrose; Polyethylene glycol, unspecified
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Mallinckrodt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose, unspecified; Polydextrose; Polyethylene glycol, unspecified
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Mayne Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 30 |
DFM Info
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Stearic acid; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Avera McKennan Hospital; H. J. Harkins Company; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Physicians Total Care; RedPharm; Stat Rx USA; West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Stearic acid; Silicon dioxide; Microcrystalline cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 32 |
DFM Info
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Anhydrous lactose; Cetostearyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Hydroxyethyl cellulose (280 mpa.s at 2%); Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Anhydrous lactose; Cetostearyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Hydroxyethyl cellulose (280 mpa.s at 2%); Polyethylene glycols; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 34 |
DFM Info
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Anhydrous lactose; Cetostearyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Hydroxyethyl cellulose (280 mpa.s at 2%); Polyethylene glycols; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Morphine 80 mg capsule | Click to Show/Hide the Full List of Formulation(s): 8 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone k30; Ethylcelluloses; Gelatin; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone k30; Ethylcelluloses; Ferric oxide black; Gelatin; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
|
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Sodium lauryl sulfate; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Fd&c yellow no. 6; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Starch, corn
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|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Sodium lauryl sulfate; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Fd&c yellow no. 6; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Kadian; Actavis Pharma; Allergan | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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D&c red no. 28; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Diethyl phthalate; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Alcohol; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Impax Generics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Sodium lauryl sulfate; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Fd&c yellow no. 6; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycol; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Sodium lauryl sulfate; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Fd&c yellow no. 6; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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Fd&c red no. 40; Diethyl phthalate; Fd&c yellow no. 6; Talc; Titanium dioxide; Polyethylene glycol 4000; Ethylcellulose, unspecified; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Upsher-Smith Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Morphine 200 mg tablet | Click to Show/Hide the Full List of Formulation(s): 17 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Butylated hydroxytoluene; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Butylated hydroxyanisole; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Aluminum oxide; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hypromelloses
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [8] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Stearic acid; Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 4000; Silicon dioxide; Hypromelloses; Povidones
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Silicon dioxide; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hydroxypropyl cellulose, low substituted; Hypromellose 2208 (100 mpa.s)
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Novel Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 3350; Silicon dioxide; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hydroxypropyl cellulose, low substituted; Hypromellose 2208 (100 mpa.s); Polyvinyl alcohol, unspecified
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 1; Fd&c yellow no. 5; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Hypromellose 2910 (15 mpa.s)
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Qualitest Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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D&c yellow no. 10; Cetostearyl alcohol; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Hypromellose; Hydroxypropyl cellulose; Polyethylene glycol; Powdered cellulose
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Aluminum oxide; Hypromellose 2208 (15000 mpa.s); Polyethylene glycol
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Aluminum oxide; Hypromellose 2208 (15000 mpa.s); Polyethylene glycol, unspecified
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Mallinckrodt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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Stearic acid; Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Hypromellose; Carnauba wax; Polyethylene glycol
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Ethex Corporation | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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D&c yellow no. 10; Cetostearyl alcohol; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 cps at 5%); Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Rhodes Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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D&c yellow no. 10; Cetostearyl alcohol; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 cps at 5%); Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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D&c yellow no. 10; Cetostearyl alcohol; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 mpa.s at 5%); Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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D&c yellow no. 10; Cetostearyl alcohol; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 mpa.s at 5%); Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Polyethylene glycol, unspecified
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Rhodes Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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D&c yellow no. 10; Cetostearyl alcohol; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 mpa.s at 5%); Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Purdue Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Anhydrous lactose; Cetostearyl alcohol; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Hydroxyethyl cellulose (280 mpa.s at 2%); Polyethylene glycols; Polyvinyl alcohol, unspecified
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Morphine 60 mg tablet | Click to Show/Hide the Full List of Formulation(s): 27 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Butylated hydroxytoluene; D&c red no. 30; D&c yellow no. 10; Magnesium stearate; Butylated hydroxyanisole; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Aluminum oxide; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hypromelloses
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [8] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [9] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Silicon dioxide; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hydroxypropyl cellulose, low substituted; Hypromellose 2208 (100 mpa.s)
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Novel Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose; D&c red no. 30; D&c yellow no. 10; Cetostearyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Hypromellose; Polysorbate 80; Polyethylene glycol; Powdered cellulose
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [9] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 3350; Silicon dioxide; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hydroxypropyl cellulose, low substituted; Hypromellose 2208 (100 mpa.s); Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose; D&c red no. 30; D&c yellow no. 10; Cetostearyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Polyethylene glycol; Powdered cellulose
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [9] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Ferric oxide red; Titanium dioxide; Triacetin; Hypromellose; Silicon dioxide; Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Magnesium stearate; Titanium dioxide; Hypromellose; Polysorbate 80; Carnauba wax; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Ethex Corporation | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Hypromellose 2208 (15000 mpa.s)
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | American Health Packaging; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Hypromellose 2910 (15 mpa.s)
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Qualitest Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Hypromelloses
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose; D&c red no. 30; D&c yellow no. 10; Cetostearyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 cps at 5%); Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals; Rhodes Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [9] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose; D&c red no. 30; D&c yellow no. 10; Cetostearyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 cps at 5%); Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols
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|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [9] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose; D&c red no. 30; D&c yellow no. 10; Cetostearyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 cps at 5%); Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycol
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [9] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose; D&c red no. 30; D&c yellow no. 10; Cetostearyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 cps at 5%); Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycol
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [9] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose; D&c red no. 30; D&c yellow no. 10; Cetostearyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 mpa.s at 5%); Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [9] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose, unspecified form; D&c red no. 30; D&c yellow no. 10; Cetostearyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 mpa.s at 5%); Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [9] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose; D&c red no. 30; D&c yellow no. 10; Cetostearyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 mpa.s at 5%); Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [9] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Ferric oxide red; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose 2208 (15000 mpa.s); Polydextrose; Polyethylene glycol, unspecified
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Mallinckrodt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Ferric oxide red; Titanium dioxide; Triacetin; Silicon dioxide; Hypromelloses; Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Ferric oxide red; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose, unspecified; Polydextrose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Mayne Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Lactose, unspecified form; D&c red no. 30; D&c yellow no. 10; Cetostearyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 mpa.s at 5%); Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Rhodes Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [9] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose; D&c red no. 30; D&c yellow no. 10; Cetostearyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 mpa.s at 5%); Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Purdue Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [9] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Anhydrous lactose; Cetostearyl alcohol; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Polyvinyl alcohol; Hydroxyethyl cellulose (280 mpa.s at 2%); Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Anhydrous lactose; Cetostearyl alcohol; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Hydroxyethyl cellulose (280 mpa.s at 2%); Polyethylene glycols; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Morphine 130 mg capsule | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sodium lauryl sulfate; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Fd&c yellow no. 6; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Kadian | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Morphine 100 mg capsule | Click to Show/Hide the Full List of Formulation(s): 9 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Fd&c blue no. 2; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone k30; Ethylcelluloses; Fd&c green no. 3; Gelatin; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Fd&c blue no. 2; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone k30; Ethylcelluloses; Fd&c green no. 3; Ferric oxide black; Gelatin; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 3 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Diethyl phthalate; Fd&c blue no. 1; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Diethyl phthalate; Fd&c blue no. 1; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Kadian; Actavis Pharma; Allergan | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Diethyl phthalate; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Hypromellose; Silicon dioxide; Ethylcellulose; Gelatin; Polyethylene glycol; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Diethyl phthalate; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycol; Starch, corn
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|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Diethyl phthalate; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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D&c yellow no. 10; Butyl alcohol; Diethyl phthalate; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Alcohol; Ethylcelluloses; Fd&c green no. 3; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Impax Generics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 9 |
DFM Info
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D&c yellow no. 10; Diethyl phthalate; Fd&c blue no. 1; Talc; Titanium dioxide; Polyethylene glycol 4000; Ethylcellulose, unspecified; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Upsher-Smith Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Morphine 40 mg capsule | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Diethyl phthalate; Fd&c blue no. 1; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Kadian; Actavis Pharma; Allergan | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Morphine 50 mg capsule | Click to Show/Hide the Full List of Formulation(s): 11 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac; Starch, corn
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|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Kadian; Actavis Pharma; Allergan | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Hypromellose; Silicon dioxide; Ethylcellulose; Gelatin; Polyethylene glycol; Starch, corn
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|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycol; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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Butyl alcohol; Diethyl phthalate; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Alcohol; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Impax Generics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Diethyl phthalate; Fd&c blue no. 1; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone k30; Ethylcelluloses; Gelatin; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Diethyl phthalate; Fd&c blue no. 1; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone k30; Ethylcelluloses; Ferric oxide black; Gelatin; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Diethyl phthalate; Fd&c blue no. 1; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone k30; Ethylcelluloses; Gelatin; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Talc; Titanium dioxide; Polyethylene glycol 4000; Ethylcellulose, unspecified; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Upsher-Smith Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Talc; Titanium dioxide; Polyethylene glycol 4000; Cellulose, microcrystalline; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Morphine 60 mg capsule | Click to Show/Hide the Full List of Formulation(s): 14 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Kadian; Actavis Pharma; Allergan; Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Hypromellose; Silicon dioxide; Ethylcellulose; Gelatin; Polyethylene glycol; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone k30; Ethylcelluloses; Gelatin; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 5 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone k30; Ethylcelluloses; Ferric oxide black; Gelatin; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 6 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycol; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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D&c yellow no. 10; Butyl alcohol; Diethyl phthalate; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Alcohol; Ethylcelluloses; Fd&c green no. 3; Gelatin; Hydroxypropyl cellulose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 9 |
DFM Info
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Fd&c red no. 40; Butyl alcohol; Diethyl phthalate; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Alcohol; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Impax Generics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Talc; Titanium dioxide; Polyethylene glycol 4000; Ethylcellulose, unspecified; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Upsher-Smith Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Drug Formulation 11 |
DFM Info
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Sodium lauryl sulfate; Fumaric acid; Talc; Titanium dioxide; Povidone; Fd&c green no. 3; Gelatin
|
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [10] | |||
| Drug Formulation 12 |
DFM Info
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Sodium lauryl sulfate; Fumaric acid; Talc; Povidone
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [10] | |||
| Drug Formulation 13 |
DFM Info
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Sodium lauryl sulfate; Fumaric acid; Talc; Titanium dioxide; Ammonio methacrylate copolymer type a; Fd&c green no. 3; Gelatin; Povidones
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Pfizer Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Drug Formulation 14 |
DFM Info
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Sodium lauryl sulfate; Fumaric acid; Talc; Titanium dioxide; Fd&c green no. 3; Gelatin; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Morphine 70 mg capsule | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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D&c red no. 28; Sodium lauryl sulfate; Diethyl phthalate; Fd&c blue no. 1; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Kadian | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Morphine 30 mg tablet | Click to Show/Hide the Full List of Formulation(s): 29 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Butylated hydroxytoluene; D&c red no. 7; Fd&c blue no. 1; Magnesium stearate; Butylated hydroxyanisole; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hypromelloses
|
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| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [8] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; D&c red no. 27; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 4000; Silicon dioxide; Hypromelloses; Povidones
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; D&c red no. 27; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Silicon dioxide; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hydroxypropyl cellulose, low substituted; Hypromellose 2208 (100 mpa.s)
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|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Novel Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Stearic acid; D&c red no. 27; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Hypromellose; Polysorbate 80; Carnauba wax; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Ethex Corporation | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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Lactose monohydrate; D&c red no. 27; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 3350; Silicon dioxide; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hydroxypropyl cellulose, low substituted; Hypromellose 2208 (100 mpa.s); Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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Stearic acid; Anhydrous lactose; D&c red no. 27; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Hypromellose, unspecified; Polyethylene glycol, unspecified
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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Stearic acid; Anhydrous lactose; D&c red no. 27; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Hypromellose 2910 (15 mpa.s)
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Qualitest Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Hypromellose 2208 (15000 mpa.s)
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | American Health Packaging; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Hypromelloses
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose; Cetostearyl alcohol; D&c red no. 7; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Hypromellose; Polysorbate 80; Polyethylene glycol; Powdered cellulose
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 13 |
DFM Info
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Lactose; Cetostearyl alcohol; D&c red no. 7; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hydroxyethyl cellulose (140 cps at 5%); Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | H. J. Harkins Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose; Cetostearyl alcohol; D&c red no. 7; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hydroxyethyl cellulose (140 cps at 5%); Hypromelloses; Polyethylene glycols
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|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 15 |
DFM Info
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Lactose; Cetostearyl alcohol; D&c red no. 7; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hydroxyethyl cellulose (140 cps at 5%); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; PD-Rx Pharmaceuticals; Rhodes Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose; Cetostearyl alcohol; D&c red no. 7; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hydroxyethyl cellulose (140 cps at 5%); Hypromelloses; Polyethylene glycol
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose; Cetostearyl alcohol; D&c red no. 7; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hydroxyethyl cellulose (140 mpa.s at 5%); Hypromelloses; Polyethylene glycols
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|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | American Health Packaging; Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose, unspecified form; Cetostearyl alcohol; D&c red no. 7; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hydroxyethyl cellulose (140 mpa.s at 5%); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose; Cetostearyl alcohol; D&c red no. 7; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Polyethylene glycols; Powdered cellulose
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose, unspecified form; Cetostearyl alcohol; D&c red no. 7; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hydroxyethyl cellulose (140 mpa.s at 5%); Hypromellose, unspecified; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Rhodes Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose; Cetostearyl alcohol; D&c red no. 7; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polysorbate 80; Hydroxyethyl cellulose (140 mpa.s at 5%); Hypromelloses; Polyethylene glycols
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Purdue Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 22 |
DFM Info
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Lactose monohydrate; D&c red no. 7; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose 2208 (15000 mpa.s); Polydextrose; Polyethylene glycol
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 23 |
DFM Info
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Lactose monohydrate; D&c red no. 7; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose 2208 (15000 mpa.s); Polydextrose; Polyethylene glycol, unspecified
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Mallinckrodt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose monohydrate; D&c red no. 7; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose, unspecified; Polydextrose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Mayne Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Lactose monohydrate; D&c red no. 7; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Stearic acid; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Dispensing Solution; H. J. Harkins Company; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Physicians Total Care; Stat Rx USA; West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Anhydrous lactose; Cetostearyl alcohol; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Polyvinyl alcohol; Hydroxyethyl cellulose (280 mpa.s at 2%); Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Anhydrous lactose; Cetostearyl alcohol; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Hydroxyethyl cellulose (280 mpa.s at 2%); Polyethylene glycols; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Morphine 100 mg tablet | Click to Show/Hide the Full List of Formulation(s): 19 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Silicon dioxide; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hydroxypropyl cellulose, low substituted; Hypromellose 2208 (100 mpa.s)
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Novel Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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Stearic acid; Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 4000; Silicon dioxide; Hypromelloses; Povidones
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Butylated hydroxytoluene; Magnesium stearate; Butylated hydroxyanisole; Ferrosoferric oxide; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hypromelloses
|
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| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [8] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 3350; Silicon dioxide; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hydroxypropyl cellulose, low substituted; Hypromellose 2208 (100 mpa.s); Polyvinyl alcohol, unspecified
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Hypromellose; Polysorbate 80; Carnauba wax; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Ethex Corporation | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Silicon dioxide; Hypromellose 2208 (15000 mpa.s)
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | American Health Packaging; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Silicon dioxide; Hypromellose 2910 (15 mpa.s)
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Qualitest Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Silicon dioxide; Hypromelloses
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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Stearic acid; Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Polysorbate 80; Carnauba wax; Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Cetostearyl alcohol; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Hypromellose; Polyethylene glycol; Powdered cellulose
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose 2208 (15000 mpa.s)
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Mallinckrodt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose, unspecified; Polydextrose; Polyethylene glycol, unspecified
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Mayne Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Anhydrous lactose; Cetostearyl alcohol; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Hydroxyethyl cellulose (280 mpa.s at 2%); Polyethylene glycols; Polyvinyl alcohol, unspecified
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Cetostearyl alcohol; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 cps at 5%); Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Avera McKennan Hospital; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Rhodes Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Cetostearyl alcohol; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 cps at 5%); Hypromelloses; Polyethylene glycol
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Cetostearyl alcohol; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Hypromelloses; Polyethylene glycol; Powdered cellulose
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Cetostearyl alcohol; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 mpa.s at 5%); Hypromellose, unspecified; Polyethylene glycol, unspecified
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Rhodes Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Cetostearyl alcohol; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Hydroxyethyl cellulose (140 mpa.s at 5%); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | American Health Packaging; Bryant Ranch Prepack; Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Morphine 150 mg capsule | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sodium lauryl sulfate; D&c yellow no. 10; Diethyl phthalate; Fd&c blue no. 1; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Kadian | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Morphine 10 mg capsule | Click to Show/Hide the Full List of Formulation(s): 5 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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D&c red no. 28; Sodium lauryl sulfate; Diethyl phthalate; Fd&c blue no. 1; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Starch, corn
|
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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D&c red no. 28; Sodium lauryl sulfate; Diethyl phthalate; Fd&c blue no. 1; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Kadian; Actavis Pharma; Allergan | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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D&c red no. 28; Sodium lauryl sulfate; Diethyl phthalate; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Hypromellose; Silicon dioxide; Ethylcellulose; Gelatin; Polyethylene glycol; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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D&c red no. 28; Sodium lauryl sulfate; Diethyl phthalate; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Talc; Titanium dioxide; Polyethylene glycol 4000; Ethylcellulose, unspecified; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Upsher-Smith Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Morphine 30 mg capsule | Click to Show/Hide the Full List of Formulation(s): 14 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Sodium lauryl sulfate; Diethyl phthalate; Fd&c blue no. 1; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Sodium lauryl sulfate; Diethyl phthalate; Fd&c blue no. 1; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Kadian; Actavis Pharma; Allergan; Bryant Ranch Prepack; Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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Sodium lauryl sulfate; Diethyl phthalate; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Hypromellose; Silicon dioxide; Ethylcellulose; Gelatin; Polyethylene glycol; Starch, corn
|
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Butyl alcohol; Diethyl phthalate; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Fd&c red no. 3; Alcohol; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Starch, corn
|
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Impax Generics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Diethyl phthalate; Fd&c blue no. 1; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Polyethylene glycol 6000; Povidone k30; Ethylcelluloses; Gelatin; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Diethyl phthalate; Fd&c blue no. 1; Propylene glycol; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Polyethylene glycol 6000; Povidone k30; Ethylcelluloses; Ferric oxide black; Gelatin; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Sodium lauryl sulfate; Diethyl phthalate; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycol; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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Sodium lauryl sulfate; Diethyl phthalate; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Starch, corn
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|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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Butyl alcohol; Diethyl phthalate; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Alcohol; Ethylcelluloses; Gelatin; Hydroxypropyl cellulose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Talc; Titanium dioxide; Polyethylene glycol 4000; Ethylcellulose, unspecified; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose
|
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Upsher-Smith Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Fd&c red no. 40; Diethyl phthalate; Fd&c blue no. 1; Talc; Titanium dioxide; Polyethylene glycol 4000; Cellulose, microcrystalline; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Fumaric acid; Talc; Titanium dioxide; Povidone; Gelatin
|
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [10] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Sodium lauryl sulfate; D&c yellow no. 10; Fumaric acid; Talc; Titanium dioxide; Ammonio methacrylate copolymer type a; Gelatin; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Pfizer Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Sodium lauryl sulfate; D&c yellow no. 10; Fumaric acid; Talc; Titanium dioxide; Gelatin; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Morphine 45 mg capsule | Click to Show/Hide the Full List of Formulation(s): 2 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Butyl alcohol; Diethyl phthalate; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Fd&c red no. 3; Alcohol; Ethylcelluloses; Gelatin; Hydroxypropyl cellulose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Sodium lauryl sulfate; Fumaric acid; Fd&c blue no. 2; Talc; Titanium dioxide; Ammonio methacrylate copolymer type a; Gelatin; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Pfizer Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Morphine 20 mg capsule | Click to Show/Hide the Full List of Formulation(s): 13 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sodium lauryl sulfate; D&c yellow no. 10; Diethyl phthalate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcellulose, unspecified; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycol, unspecified; Shellac; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Sodium lauryl sulfate; D&c yellow no. 10; Diethyl phthalate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Sodium lauryl sulfate; D&c yellow no. 10; Diethyl phthalate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Kadian; Actavis Pharma; Allergan; Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Sodium lauryl sulfate; D&c yellow no. 10; Diethyl phthalate; Sucrose; Talc; Titanium dioxide; Hypromellose; Silicon dioxide; Ethylcellulose; Gelatin; Polyethylene glycol; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [10] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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D&c yellow no. 10; Diethyl phthalate; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone k30; Ethylcelluloses; Gelatin; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 6 |
DFM Info
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D&c yellow no. 10; Diethyl phthalate; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone k30; Ethylcelluloses; Gelatin; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
|
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 7 |
DFM Info
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D&c yellow no. 10; Diethyl phthalate; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone k30; Ethylcelluloses; Ferric oxide black; Gelatin; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
|
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 8 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Diethyl phthalate; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycol; Starch, corn
|
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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|
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Sodium lauryl sulfate; D&c yellow no. 10; Diethyl phthalate; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Diethyl phthalate; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Starch, corn
|
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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Butyl alcohol; Diethyl phthalate; Isopropyl alcohol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Alcohol; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Impax Generics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 12 |
DFM Info
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D&c yellow no. 10; Diethyl phthalate; Talc; Titanium dioxide; Polyethylene glycol 4000; Ethylcellulose, unspecified; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Upsher-Smith Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|
|||||
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D&c yellow no. 10; Diethyl phthalate; Talc; Titanium dioxide; Polyethylene glycol 4000; Cellulose, microcrystalline; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Morphine 90 mg capsule | Click to Show/Hide the Full List of Formulation(s): 5 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|
|||||
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Butyl alcohol; Diethyl phthalate; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Alcohol; Ethylcelluloses; Gelatin; Hydroxypropyl cellulose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Talc; Titanium dioxide; Povidone; Gelatin
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [10] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Talc; Titanium dioxide; Ammonio methacrylate copolymer type a; Gelatin; Povidones
|
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Pfizer Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Talc; Titanium dioxide; Gelatin; Povidones
|
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Sodium lauryl sulfate; Fumaric acid; Talc; Povidone
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [10] | |||
| Morphine 120 mg capsule | Click to Show/Hide the Full List of Formulation(s): 3 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Butyl alcohol; Diethyl phthalate; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Alcohol; Ethylcelluloses; Gelatin; Hydroxypropyl cellulose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Sodium lauryl sulfate; Fumaric acid; Fd&c blue no. 1; Talc; Titanium dioxide; Fd&c red no. 3; Ammonio methacrylate copolymer type a; Gelatin; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Pfizer Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Sodium lauryl sulfate; Fumaric acid; Talc; Povidone
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [10] | |||
| Morphine 200 mg capsule | Click to Show/Hide the Full List of Formulation(s): 3 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sodium lauryl sulfate; Diethyl phthalate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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|
|||||
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Sodium lauryl sulfate; Diethyl phthalate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Actavis Kadian; Actavis Pharma; Allergan | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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|
|||||
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Sodium lauryl sulfate; Diethyl phthalate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycol; Starch, corn
|
|||||
| Dosage Form | Extended Release Oral Capsule | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Morphine 75 mg capsule | Click to Show/Hide the Full List of Formulation(s): 2 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|
|||||
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Butyl alcohol; Diethyl phthalate; Isopropyl alcohol; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Alcohol; Ethylcelluloses; Gelatin; Hydroxypropyl cellulose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|
|||||
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Sodium lauryl sulfate; Fumaric acid; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Ammonio methacrylate copolymer type a; Gelatin; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Pfizer Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
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