Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00242) | |||||
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| Name |
Escitalopram
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| Synonyms |
Click to Show/Hide the Synonyms of This API
Escitalopram; 128196-01-0; (S)-Citalopram; S(+)-Citalopram; (+)-Citalopram; Seroplex; S-(+)-Citalopram; Cipralex; (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; UNII-4O4S742ANY; Esertia; CHEMBL1508; (s)-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile; 4O4S742ANY; R-Citalopram; CHEBI:36791; 5-Isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-, (1S)-; 5-Isobenzofurancarbonitrile, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-, (1S)-; Esertia (TN); Escitalopram (INN); Escitalopram [INN:BAN]; escitalopramum; 1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile; Spectrum_001401; Tocris-1427; Spectrum2_000551; Spectrum3_001062; Spectrum4_001212; Spectrum5_001693; Lopac-C-7861; (+)-(S)-1-(3-(Dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile; BIDD:PXR0135; SCHEMBL34948; BSPBio_002644; KBioGR_001644; KBioSS_001881; SPBio_000621; GTPL7177; DTXSID8048440; HSDB 8410; KBio2_001881; KBio2_004449; KBio2_007017; KBio3_001864; HMS2089O08; (S)-Citalopram;S-(+)-Citalopram; BCP12154; EBD32686; ZINC3800706; BDBM50302225; AKOS017343470; 2-METHOXYETHYLP-TOLUENESULFONATE; AC-1594; AC-4508; CS-2053; DB01175; SB17453; (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-isobenzofuran-5-carbonitrile; MRF-0000226; NCGC00015267-01; NCGC00015267-02; NCGC00015267-03; NCGC00015267-06; NCGC00025160-01; NCGC00178555-01; NCGC00178555-07; HY-14258; LU-26-054; D07913; AB00698374-07; AB00698374-09; AB00698374_10; 118335-EP2275420A1; 118335-EP2298764A1; 118335-EP2298765A1; Q423757; J-005570; BRD-K70301876-034-02-0; UNII-0DHU5B8D6V component WSEQXVZVJXJVFP-FQEVSTJZSA-N; (s)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5 carbonitrile; (S)-(+)-1-[3-(dimethylamino) propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile; (S)-(+)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile
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| Clinical Status |
Approved
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| Disease Indication | Major depressive disorder | ICD-11: 6A70 | [1] | ||
| PubChem CID | |||||
| Formula |
C20H21FN2O
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| Canonical SMILES |
CN(C)CCC[C@@]1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
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| InChI |
1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3/t20-/m0/s1
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| InChIKey |
WSEQXVZVJXJVFP-FQEVSTJZSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=146570"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 324.4 | Topological Polar Surface Area | 36.3 | |
| XlogP | 3.2 | Complexity | 466 | ||
| Heavy Atom Count | 24 | Rotatable Bond Count | 5 | ||
| Hydrogen Bond Donor Count | 0 | Hydrogen Bond Acceptor Count | 4 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
|---|---|---|---|---|---|---|
| Escitalopram 10 mg tablet | Click to Show/Hide the Full List of Formulation(s): 37 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; Isopropyl alcohol; Magnesium stearate; Propyl gallate; Talc; Titanium dioxide; Carboxymethylcellulose sodium; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Macleods Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propyl gallate | DIG Info | Arachidonate 5-lipoxygenase (Ki = 0.43 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [3] | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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Butylated hydroxytoluene; Magnesium stearate; Butylated hydroxyanisole; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Hypromellose 2910 (5 mpa.s); Microcrystalline cellulose
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging; Cardinal Health; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [7] | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 3 |
DFM Info
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Butylated hydroxytoluene; Magnesium stearate; Butylated hydroxyanisole; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; Citron Pharma; PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [7] | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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Magnesium stearate; Mannitol; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 6000; Cellulose, microcrystalline; Hypromellose 2910 (15 mpa.s); Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Avera McKennan Hospital; Contract Pharmacal; NCS HealthCare of KY, Inc dba Vangard Labs; PD-Rx Pharmaceuticals; Proficient Rx; Raritan Pharmaceuticals; RemedyRepack; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 5 |
DFM Info
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Magnesium stearate; Mannitol; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 6000; Hypromellose 2910 (15 mpa.s); Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Preferred Pharamaceuticals; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 6 |
DFM Info
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Magnesium stearate; Mannitol; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 6000; Cellulose, microcrystalline; Hypromellose 2910 (15 mpa.s); Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | International Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Magnesium stearate; Mannitol; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 8 |
DFM Info
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Magnesium stearate; Mannitol; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 9 |
DFM Info
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 10 |
DFM Info
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Povidone k12
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 11 |
DFM Info
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Legacy Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 12 |
DFM Info
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Povidone; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | DirectRX; Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Povidones
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Blenheim Phamacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 14 |
DFM Info
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; Camber Pharmaceuticals; Legacy Pharmaceutical; TYA Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 15 |
DFM Info
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Exelan Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 16 |
DFM Info
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 300; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (100 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Dispensing Solution; Hikma Pharmaceutical; PD-Rx Pharmaceuticals; West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 300 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 54 %) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 17 |
DFM Info
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Cipla | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 18 |
DFM Info
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Povidone k12
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 19 |
DFM Info
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Povidone, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 20 |
DFM Info
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Magnesium stearate; Butylated hydroxyanisole; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Amneal Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 21 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 22 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Butylated hydroxyanisole; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 23 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Butylated hydroxyanisole; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 24 |
DFM Info
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 25 |
DFM Info
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 26 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Butylated hydroxyanisole; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type m); Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 27 |
DFM Info
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Lupin Pharmaceuticals; NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Drug Formulation 28 |
DFM Info
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; Allergan; Blenheim Phamacal; Cardinal Health; PD-Rx Pharmaceuticals; Physicians Total Care; RemedyRepack; Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 29 |
DFM Info
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Cardinal Health; Mylan Pharamceuticals; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 30 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Butylated hydroxyanisole; Titanium dioxide; Croscarmellose sodium; Hydroxypropyl cellulose (700000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 31 |
DFM Info
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Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Hypromellose 2910 (15000 mpa.s); Microcrystalline cellulose
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| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 32 |
DFM Info
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Magnesium stearate; Talc; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (15000 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Accord Healthcare; Bryant Ranch Prepack; Lake Eire Medical & Surgical Supply DBA Quality Care Products; RedPharm; RemedyRepack; St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Magnesium stearate; Talc; Croscarmellose sodium; Silicon dioxide
|
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 35 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | STI Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 36 |
DFM Info
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Magnesium stearate; Titanium dioxide; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Mannitol hexanitrate; Polyethylene glycols; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Escitalopram 20 mg tablet | Click to Show/Hide the Full List of Formulation(s): 37 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; Isopropyl alcohol; Magnesium stearate; Propyl gallate; Talc; Titanium dioxide; Carboxymethylcellulose sodium; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Macleods Pharmaceuticals; NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propyl gallate | DIG Info | Arachidonate 5-lipoxygenase (Ki = 0.43 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [3] | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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Butylated hydroxytoluene; Magnesium stearate; Butylated hydroxyanisole; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Hypromellose 2910 (5 mpa.s); Microcrystalline cellulose
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [7] | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Butylated hydroxytoluene; Magnesium stearate; Butylated hydroxyanisole; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; Citron Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [7] | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 6000; Cellulose, microcrystalline; Hypromellose 2910 (15 mpa.s); Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | International Laboratories; Lake Eire Medical & Surgical Supply DBA Quality Care Products; McKesson; NCS HealthCare of KY, Inc dba Vangard Labs; PD-Rx Pharmaceuticals; Proficient Rx; RedPharm; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 6000; Hypromellose 2910 (15 mpa.s); Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Rebel Distributors; Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Starch, pregelatinized corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal; NuCare Pharmaceuticals; RemedyRepack; St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Povidone k12
|
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Legacy Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Povidone; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromellose 2910 (6 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | DirectRX; Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Aidarex Pharmaceuticals; Blenheim Phamacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Polyethylene glycols
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Camber Pharmaceuticals; Legacy Pharmaceutical; TYA Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Cipla; Exelan Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 300; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (100 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Hikma Pharmaceutical; PD-Rx Pharmaceuticals; West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 300 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 54 %) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Polyethylene glycols
|
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Magnesium stearate; Butylated hydroxyanisole; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Amneal Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Butylated hydroxyanisole; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Butylated hydroxyanisole; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Butylated hydroxyanisole; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type m); Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lupin Pharmaceuticals; NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; Allergan; Blenheim Phamacal; Cardinal Health; PD-Rx Pharmaceuticals; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Cardinal Health; Contract Pharmacal; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Butylated hydroxyanisole; Titanium dioxide; Croscarmellose sodium; Hydroxypropyl cellulose (700000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
|
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| Dosage Form | Oral Tablet | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Hypromellose 2910 (15000 mpa.s); Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Magnesium stearate; Talc; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (15000 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Accord Healthcare; Bryant Ranch Prepack; DirectRX; Lake Eire Medical & Surgical Supply DBA Quality Care Products; NuCare Pharmaceuticals; RemedyRepack; St Marys Medical Park Pharmacy; TYA Pharmaceuticals; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Magnesium stearate; Talc; Croscarmellose sodium; Silicon dioxide
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (15000 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 35 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | STI Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 36 |
DFM Info
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|||||
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Magnesium stearate; Titanium dioxide; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Mannitol hexanitrate; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Escitalopram 5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 21 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; Isopropyl alcohol; Magnesium stearate; Propyl gallate; Talc; Titanium dioxide; Carboxymethylcellulose sodium; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Hypromellose 2910 (6 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Macleods Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propyl gallate | DIG Info | Arachidonate 5-lipoxygenase (Ki = 0.43 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [3] | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Butylated hydroxytoluene; Magnesium stearate; Butylated hydroxyanisole; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; Citron Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [7] | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 6000; Cellulose, microcrystalline; Hypromellose 2910 (15 mpa.s); Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Avera McKennan Hospital; NCS HealthCare of KY, Inc dba Vangard Labs; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 6000; Hypromellose 2910 (15 mpa.s); Microcrystalline cellulose; Starch, corn
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|
|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 6 |
DFM Info
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|
|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 7 |
DFM Info
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|
|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Povidone; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|
|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Povidones
|
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| Dosage Form | Oral Tablet | |||||
| Company | Blenheim Phamacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 9 |
DFM Info
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|
|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Camber Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 10 |
DFM Info
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|
|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Polyethylene glycols
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cipla; Exelan Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 11 |
DFM Info
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|
|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 300; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (100 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Hikma Pharmaceutical; West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 300 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 54 %) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 12 |
DFM Info
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|
|||||
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Magnesium stearate; Butylated hydroxyanisole; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Amneal Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Butylated hydroxyanisole; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type m); Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylhydroxyanisole | DIG Info | Prostaglandin G/H synthase 2 (IC50 = 2.6 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Lupin Pharmaceuticals; NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Allergan; Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Avera McKennan Hospital; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (15000 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Accord Healthcare; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Magnesium stearate; Talc; Croscarmellose sodium; Silicon dioxide
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | STI Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
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