Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00083) | |||||
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| Name |
Bupropion
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| Synonyms |
Click to Show/Hide the Synonyms of This API
Amfebutamone; 34911-55-2; 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one; Amfebutamon; Wellbutrin; amfebutamonum; Amfebutamona; (+-)-Bupropion; 34841-39-9; Elontril; Wellbatrin; AMFEBUTAMONE HCl; Bupropion SR; Bupropion hydrocloride; CHEMBL894; alpha-(tert-butylamino)-m-chloropropiophenone; CHEBI:3219; (+-)-1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone; Bupropion [INN:BAN]; Amfebutamonum [INN-Latin]; Amfebutamona [INN-Spanish]; 1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]propan-1-one; UNII-01ZG3TPX31; Bupropion (INN); Bupropion (USAN); BW-323; NSC315851; bupropion (amfebutamone); BRN 2101062; 01ZG3TPX31; Zyban (Salt/Mix); Budeprion (Salt/Mix); Spectrum_001663; Wellbutrin (Salt/Mix); SpecPlus_000954; (.+/-.)-Bupropion; 2-(Tert-Butylamino)-3'-chloropropiophenone; Prestwick0_000249; Prestwick1_000249; Prestwick2_000249; Prestwick3_000249; Spectrum2_001659; Spectrum3_000644; Spectrum4_000614; Spectrum5_001406; (+-)-2-(tert-Butylamino)-3'-chlorpropiophenon; Lopac0_000166; SCHEMBL38777; BSPBio_000038; BSPBio_002247; KBioGR_001168; KBioSS_002143; (+-)-2-(tert-Butylamino)-3'-chloropropiophenone; MLS001424015; DivK1c_007050; SPBio_001817; SPBio_002257; BPBio1_000042; GTPL7135; DTXSID7022706; HSDB 6988; KBio1_001994; KBio2_002143; KBio2_004711; KBio2_007279; KBio3_001467; HMS2051G10; HMS2089G14; HMS2232P04; HMS3369P11; HMS3393G10; 1-Propanone, 1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-; BCP24193; 8068AH; AC-197; BBL029065; BDBM50048392; STL373006; 1-Propanone, 1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-, (+-)-; AKOS015961770; CCG-100858; CCG-204261; DB01156; NC00108; SDCCGSBI-0050154.P004; MRF-0000143; NCGC00015122-03; NCGC00015122-04; NCGC00015122-06; NCGC00015122-07; NCGC00015122-09; NCGC00015122-14; NCGC00015122-20; NCGC00089751-02; AM807634; NCI60_002714; SMR000472526; SBI-0050154.P003; DB-048697; AB00053756; .alpha.-(tert-Butylamino)-m-chloropropiophenone; 3'-Chloro-alpha-(tert-butylamino)propiophenone; C-6222; C06860; D07591; Propiophenone, 2-(tert-butylamino)-3'-chloro-; AB00053756-16; AB00053756-18; AB00053756-19; AB00053756_20; AB00053756_21; 2-tert-Butylamino-1-(3-chlorophenyl)propan-1-one; L000725; Q834280; (.+/-.)-2-(tert-Butylamino)-3'-chloropropiophenone; BRD-A05186015-003-05-7; BRD-A05186015-003-09-9; 2-(tert-Butylamino)-1-(3-chlorophenyl)-1-propanone #; 1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone; 1-Propanone, 1-(3-chlorophenyl)-2-[(1, 1-dimethylethyl)amino]-; 1-Propanone, 1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-, (.+/-.)-
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| Clinical Status |
Approved
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| Disease Indication | Nicotine dependence | ICD-11: 6C4A | [1] | ||
| PubChem CID | |||||
| Formula |
C13H18ClNO
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| Canonical SMILES |
CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C
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| InChI |
1S/C13H18ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3
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| InChIKey |
SNPPWIUOZRMYNY-UHFFFAOYSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=444"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 239.74 | Topological Polar Surface Area | 29.1 | |
| XlogP | 3.2 | Complexity | 247 | ||
| Heavy Atom Count | 16 | Rotatable Bond Count | 4 | ||
| Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 2 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
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| Bupropion 150 mg tablet | Click to Show/Hide the Full List of Formulation(s): 92 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Saccharin; Stearic acid; Lactose monohydrate; Sodium lauryl sulfate; Butyl alcohol; Dibutyl sebacate; Fd&c yellow no. 6; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Propylene glycol; Sodium bicarbonate; Talc; Triethyl citrate; Crospovidone; Polysorbate 80; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hydroxypropyl cellulose (type h); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac
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| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Benzosulfimide | DIG Info | Carbonic anhydrase VII (Ki = 10 nM) | [2] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Mannitol; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Polyethylene glycol 3350; Polyethylene glycol 400; Polyvinyl alcohol; Hydrogenated castor oil; Hypromelloses; Povidones
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| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Jubilant Cadista Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Drug Formulation 3 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Hydrochloric acid; Magnesium stearate; Mannitol; Ferrosoferric oxide; Propylene glycol; Talc; Triethyl citrate; Polysorbate 80; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
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Hydrochloric acid; D&c red no. 27; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Povidone; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Hydrogenated cottonseed oil; Hydroxypropyl cellulose
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| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 5 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Hydrochloric acid; D&c red no. 27; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Povidone; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Hydrogenated cottonseed oil; Hydroxypropyl cellulose
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| Dosage Form | 12 HR Extended Release Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 6 |
DFM Info
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Hydrochloric acid; D&c red no. 27; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Povidone; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Hydrogenated cottonseed oil; Hydroxypropyl cellulose
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| Dosage Form | Smoking Cessation 12 HR Extended Release Oral Tablet | |||||
| Company | Anchen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 7 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Mannitol; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Polyethylene glycol 3350; Polyvinyl alcohol; Hydrogenated castor oil; Hypromelloses; Povidones
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| Dosage Form | Smoking Cessation 12 HR Extended Release Oral Tablet | |||||
| Company | Jubilant Cadista Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Drug Formulation 8 |
DFM Info
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Sodium lauryl sulfate; Hydrochloric acid; Magnesium stearate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Water; Polyvinyl alcohol; Povidone; Silicon dioxide; Silicon dioxide; Copovidone; Hydroxypropyl cellulose; Methacrylic acid; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 9 |
DFM Info
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Stearic acid; Hydrochloric acid; Magnesium stearate; Mannitol; Ferrosoferric oxide; Propylene glycol; Talc; Triethyl citrate; Polysorbate 80; Silicon dioxide; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Povidone, unspecified
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 10 |
DFM Info
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Stearic acid; D&c yellow no. 10; Fd&c red no. 40; Hydrochloric acid; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
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| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Cardinal Health; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 11 |
DFM Info
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Stearic acid; D&c yellow no. 10; Fd&c red no. 40; Hydrochloric acid; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
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| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 12 |
DFM Info
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Stearic acid; D&c yellow no. 10; Fd&c red no. 40; Hydrochloric acid; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
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| Dosage Form | Smoking Cessation 12 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 13 |
DFM Info
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Sodium lauryl sulfate; Hydrochloric acid; Magnesium stearate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Water; Polyvinyl alcohol; Povidone; Silicon dioxide; Copovidone; Hydroxypropyl cellulose; Methacrylic acid; Polyethylene glycol
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| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 14 |
DFM Info
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Sodium lauryl sulfate; Hydrochloric acid; Magnesium stearate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Water; Polyvinyl alcohol; Povidone; Silicon dioxide; Copovidone; Hydroxypropyl cellulose; Methacrylic acid; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 15 |
DFM Info
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Stearic acid; Fd&c red no. 40; Fd&c blue no. 2; Glyceryl dibehenate; Magnesium stearate; Mannitol; Ammonium chloride; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h)
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 16 |
DFM Info
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Stearic acid; Fd&c red no. 40; Fd&c blue no. 2; Glyceryl dibehenate; Magnesium stearate; Mannitol; Ammonium chloride; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Stearic acid; Fd&c red no. 40; Fd&c blue no. 2; Glyceryl dibehenate; Magnesium stearate; Mannitol; Ammonium chloride; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Fd&c red no. 40; Hydrochloric acid; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Cipla; Lake Eire Medical & Surgical Supply DBA Quality Care Products; PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 19 |
DFM Info
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Sodium lauryl sulfate; Hydrochloric acid; Magnesium stearate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Water; Polyvinyl alcohol; Silicon dioxide; Copovidone k25-31; Hydroxypropyl cellulose (type h); Methacrylic acid; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 20 |
DFM Info
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Sodium lauryl sulfate; Hydrochloric acid; Magnesium stearate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Water; Polyvinyl alcohol; Silicon dioxide; Hydroxypropyl cellulose (type h); Methacrylic acid; Polyethylene glycols; Povidones; Pvp/va copolymer
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 21 |
DFM Info
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Sodium lauryl sulfate; Hydrochloric acid; Magnesium stearate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Water; Polyvinyl alcohol; Silicon dioxide; Copovidone k25-31; Hydroxypropyl cellulose (type h); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones
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|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 22 |
DFM Info
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Sodium lauryl sulfate; Hydrochloric acid; Magnesium stearate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Water; Polyvinyl alcohol; Silicon dioxide; Copovidone k25-31; Hydroxypropyl cellulose (type h); Methacrylic acid; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis South Atlantic; McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 23 |
DFM Info
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Sodium lauryl sulfate; Hydrochloric acid; Magnesium stearate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Water; Polyvinyl alcohol; Silicon dioxide; Copovidone k25-31; Hydroxypropyl cellulose (type h); Methacrylic acid; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | BluePoint Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 24 |
DFM Info
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Sodium lauryl sulfate; Hydrochloric acid; Magnesium stearate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Povidone; Silicon dioxide; Copovidone; Hydroxypropyl cellulose (type h); Methacrylic acid; Polyethylene glycols; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 25 |
DFM Info
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Sodium lauryl sulfate; Hydrochloric acid; Magnesium stearate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Polyvinyl alcohol; Silicon dioxide; Copovidone k25-31; Hydroxypropyl cellulose (type h); Methacrylic acid; Polyethylene glycols; Povidones
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 26 |
DFM Info
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Saccharin; Stearic acid; Anhydrous lactose; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Silicon dioxide; Hydroxypropyl cellulose (type h)
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Preferred Pharamaceuticals; Proficient Rx; RemedyRepack; Sun Pharmaceutical Industries; TYA Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Benzosulfimide | DIG Info | Carbonic anhydrase VII (Ki = 10 nM) | [2] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Saccharin; Stearic acid; Anhydrous lactose; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Silicon dioxide; Hydroxypropyl cellulose
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | DirectRX; Medsource Pharmaceuticals; PD-Rx Pharmaceuticals; RxChange; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Benzosulfimide | DIG Info | Carbonic anhydrase VII (Ki = 10 nM) | [2] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Saccharin; Stearic acid; Anhydrous lactose; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Silicon dioxide; Hydroxypropyl cellulose
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Benzosulfimide | DIG Info | Carbonic anhydrase VII (Ki = 10 nM) | [2] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 29 |
DFM Info
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Stearic acid; Lactose monohydrate; Hydrochloric acid; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Microcrystalline cellulose
|
|||||
| Dosage Form | Smoking Cessation 12 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Fd&c red no. 40; Cysteine hydrochloride; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 6000; Cellulose, microcrystalline; Hypromellose 2910 (4000 mpa.s); Hypromellose 2910 (6 mpa.s)
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|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Cysteine hydrochloride | DIG Info | ABHD5-Perilipin complex (IC50 = 7335 nM) | [14] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Fd&c red no. 40; Cysteine hydrochloride; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Cysteine hydrochloride | DIG Info | ABHD5-Perilipin complex (IC50 = 7335 nM) | [14] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Fd&c red no. 40; Cysteine hydrochloride; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Polysorbate 80; Cellulose, microcrystalline; Copovidone; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; ScieGen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Cysteine hydrochloride | DIG Info | ABHD5-Perilipin complex (IC50 = 7335 nM) | [14] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Fd&c red no. 40; Cysteine hydrochloride; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Smoking Cessation 12 HR Extended Release Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Cysteine hydrochloride | DIG Info | ABHD5-Perilipin complex (IC50 = 7335 nM) | [14] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Sodium stearyl fumarate; Cysteine hydrochloride; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Butyl acrylate/c16-c20 alkyl methacrylate/methacrylic acid/methyl methacrylate copolymer; Ethylcelluloses; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Povidones; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Jubilant Cadista Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Cysteine hydrochloride | DIG Info | ABHD5-Perilipin complex (IC50 = 7335 nM) | [14] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [16] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 35 |
DFM Info
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Sodium lauryl sulfate; Hydrochloric acid; Magnesium stearate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Copovidone; Hydroxypropyl cellulose (1200000 mw); Methacrylic acid; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 36 |
DFM Info
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|||||
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Sodium lauryl sulfate; Hydrochloric acid; Magnesium stearate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Copovidone k25-31; Hydroxypropyl cellulose (1200000 mw); Methacrylic acid; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Stearic acid; Hydrochloric acid; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Ethylcellulose (45 mpa.s); Hydroxypropyl cellulose (120000 mw); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 38 |
DFM Info
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|||||
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Cysteine hydrochloride; Dibutyl sebacate; Ammonia; Ferrosoferric oxide; Propylene glycol; Triethyl citrate; Povidone; Silicon dioxide; Ethylcelluloses; Glyceryl behenate/eicosadioate; Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyvinyl alcohol, unspecified; Shellac; Silica dimethyl silylate
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Lupin Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Cysteine hydrochloride | DIG Info | ABHD5-Perilipin complex (IC50 = 7335 nM) | [14] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 39 |
DFM Info
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|||||
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Saccharin; Stearic acid; Anhydrous lactose; Talc; Titanium dioxide; Polyethylene glycol 3350; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Benzosulfimide | DIG Info | Carbonic anhydrase VII (Ki = 10 nM) | [2] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 40 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c red no. 40; Fd&c yellow no. 5; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 41 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c red no. 40; Fd&c yellow no. 5; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Medsource Pharmaceuticals; Proficient Rx; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 42 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Fd&c yellow no. 5; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 43 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c red no. 40; Fd&c yellow no. 5; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polydextrose; Polyethylene glycols
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|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Impax Generics; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 44 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c red no. 40; Fd&c yellow no. 5; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 45 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Hydrochloric acid; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polyethylene glycol
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack; Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 46 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Hydrochloric acid; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging; Aphena Pharma Solutions-Tennessee; Golden State Medical Supply; Lake Eire Medical & Surgical Supply DBA Quality Care Products; NCS HealthCare of KY, Inc dba Vangard Labs; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; Preferred Pharamaceuticals; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 47 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Hydrochloric acid; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydroxypropyl cellulose; Hydroxypropyl cellulose
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Drug Formulation 48 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Hydrochloric acid; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polyethylene glycol
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 49 |
DFM Info
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Hydrochloric acid; Magnesium stearate; Talc; Triethyl citrate; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Copovidone; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; ScieGen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 50 |
DFM Info
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Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Eon Labs; Major Pharmaceuticals; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 51 |
DFM Info
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|||||
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Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Contract Pharmacal; McKesson; NCS HealthCare of KY, Inc dba Vangard Labs; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 52 |
DFM Info
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|||||
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Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 53 |
DFM Info
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|||||
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Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 54 |
DFM Info
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|||||
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Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 55 |
DFM Info
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|||||
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Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 56 |
DFM Info
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|||||
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Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 57 |
DFM Info
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|||||
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Hydrochloric acid; Isopropyl alcohol; Povidone; Silicon dioxide; Alcohol; Ethylcelluloses; Hydrogenated cottonseed oil; Hydroxypropyl cellulose (type h); Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | DirectRX; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 58 |
DFM Info
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|||||
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Hydrochloric acid; Isopropyl alcohol; Povidone; Silicon dioxide; Alcohol; Ethylcelluloses; Hydrogenated cottonseed oil; Hydroxypropyl cellulose (type h); Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Contract Pharmacal; PD-Rx Pharmaceuticals; Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 59 |
DFM Info
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|||||
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Hydrochloric acid; Isopropyl alcohol; Povidone; Silicon dioxide; Alcohol; Ethylcelluloses; Hydrogenated cottonseed oil; Hydroxypropyl cellulose; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 60 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Citric acid monohydrate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | BluePoint Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 61 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Citric acid monohydrate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Cipla; Contract Pharmacal; Preferred Pharamaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 62 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Citric acid monohydrate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 63 |
DFM Info
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|||||
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Stearic acid; Hydrochloric acid; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hydroxypropyl cellulose (type h); Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma; Aidarex Pharmaceuticals; BluePoint Laboratories; Proficient Rx; St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 64 |
DFM Info
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|||||
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Fd&c red no. 40; Fd&c blue no. 2; Glyceryl dibehenate; Magnesium stearate; Talc; Titanium dioxide; Copovidone k25-31; Hydroxypropyl cellulose (1200000 mw); Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 65 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Hydrochloric acid; Magnesium stearate; Titanium dioxide; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydroxypropyl cellulose; Polyethylene glycol
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | H. J. Harkins Company; Kaiser Foundation Hospitals; Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 66 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Hydrochloric acid; Magnesium stearate; Titanium dioxide; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydroxypropyl cellulose; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 67 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (200000 mw); Hydroxypropyl cellulose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 68 |
DFM Info
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|||||
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Hydrochloric acid; Isopropyl alcohol; Silicon dioxide; Alcohol; Ethylcelluloses; Hydrogenated cottonseed oil; Hydroxypropyl cellulose (type h); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 69 |
DFM Info
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|||||
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Hydrochloric acid; Isopropyl alcohol; Silicon dioxide; Alcohol; Ethylcellulose, unspecified; Hydrogenated cottonseed oil; Hydroxypropyl cellulose (1200000 mw); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 70 |
DFM Info
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|||||
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Hydrochloric acid; Isopropyl alcohol; Silicon dioxide; Alcohol; Ethylcellulose, unspecified; Hydrogenated cottonseed oil; Hydroxypropyl cellulose (1200000 mw); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 71 |
DFM Info
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|||||
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Hydrochloric acid; Isopropyl alcohol; Silicon dioxide; Alcohol; Ethylcelluloses; Hydrogenated cottonseed oil; Hydroxypropyl cellulose (type h); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; AvKARE; BluePoint Laboratories; NCS HealthCare of KY, Inc dba Vangard Labs; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 72 |
DFM Info
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|||||
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Hydrochloric acid; Povidone; Silicon dioxide; Alcohol; Ethylcellulose; Hydroxypropyl cellulose
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs; Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 73 |
DFM Info
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|||||
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Stearic acid; Hydrochloric acid; Talc; Titanium dioxide; Triethyl citrate; Cellulose, microcrystalline; Colloidal silicon dioxide; Ethylcellulose; Hydroxypropyl cellulose; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Drug Formulation 74 |
DFM Info
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|||||
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Stearic acid; Hydrochloric acid; Talc; Titanium dioxide; Triethyl citrate; Cellulose, microcrystalline; Colloidal silicon dioxide; Ethylcelluloses; Hydroxypropyl cellulose; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dispensing Solution; Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Drug Formulation 75 |
DFM Info
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|||||
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Glyceryl dibehenate; Magnesium stearate; Ammonium chloride; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Polyvinyl alcohol; Povidone; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 76 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Polyethylene glycol 1000; Silicon dioxide; Cellulose, microcrystalline; Copovidone; Hydroxypropyl cellulose (120000 mw); Hypromelloses; Polydextrose
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Liberty Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyethylene glycol 1000 | DIG Info | Cytochrome P450 2E1 (IC50 = 75.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 77 |
DFM Info
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|||||
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Glyceryl behenate; Triethyl citrate; Polyvinyl alcohol; Povidone; Silicon dioxide; Ethylcelluloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 78 |
DFM Info
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|||||
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Glyceryl dibehenate; Triethyl citrate; Polyvinyl alcohol; Povidone; Silicon dioxide; Ethylcelluloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 79 |
DFM Info
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|||||
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Glyceryl behenate; Triethyl citrate; Polyvinyl alcohol; Povidone; Silicon dioxide; Ethylcelluloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Tablet | |||||
| Company | BTA Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 80 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Copovidone; Hydroxypropyl cellulose; Hypromelloses; Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Actavis South Atlantic; Dispensing Solution | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 81 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Copovidone; Hydroxypropyl cellulose; Hypromelloses; Polydextrose
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 82 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Copovidone k25-31; Hydroxypropyl cellulose (type h); Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 83 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Copovidone k25-31; Hydroxypropyl cellulose; Hypromelloses; Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 84 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Copovidone k25-31; Hydroxypropyl cellulose; Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging; NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 85 |
DFM Info
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Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type e); Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 86 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 87 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 88 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Copovidone k25-31; Hydroxypropyl cellulose (type h); Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | Smoking Cessation 12 HR Extended Release Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 89 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | Smoking Cessation 12 HR Extended Release Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 90 |
DFM Info
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|||||
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Glyceryl dibehenate; Triethyl citrate; Silicon dioxide; Ethylcellulose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 91 |
DFM Info
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|||||
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Glyceryl dibehenate; Triethyl citrate; Silicon dioxide; Ethylcellulose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Valeant Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 92 |
DFM Info
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|||||
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Glyceryl dibehenate; Silicon dioxide; Copovidone; Ethylcelluloses; Hydroxypropyl cellulose (type h); Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Epic Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Bupropion 100 mg tablet | Click to Show/Hide the Full List of Formulation(s): 54 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Mannitol; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Polyethylene glycol 3350; Polyethylene glycol 400; Polyvinyl alcohol; Hydrogenated castor oil; Hypromelloses; Povidones
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Jubilant Cadista Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Glutamic acid hydrochloride; Fd&c red no. 40; Maleic acid; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Glutamic acid hydrochloride | DIG Info | Glutamate receptor mGLU8 (IC50 = 5.7 nM) | [10] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Maleic acid | DIG Info | D-amino acid oxidase (IC50 = 357000 nM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Hydrochloric acid; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Povidone; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Hydrogenated cottonseed oil; Hydroxypropyl cellulose
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Hydrochloric acid; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Povidone; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Hydrogenated cottonseed oil; Hydroxypropyl cellulose
|
|||||
| Dosage Form | 12 HR Extended Release Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Hydrochloric acid; Fd&c blue no. 2; Fd&c yellow no. 6; Titanium dioxide; Triacetin; Crospovidone; Hypromellose; Silicon dioxide; Cellulose, microcrystalline; Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Stearic acid; D&c yellow no. 10; Fd&c red no. 40; Hydrochloric acid; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Stearic acid; D&c yellow no. 10; Fd&c red no. 40; Hydrochloric acid; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Hydrochloric acid; Fd&c blue no. 2; Fd&c yellow no. 6; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (100 mpa.s); Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Hydrochloric acid; Fd&c blue no. 2; Fd&c yellow no. 6; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Golden State Medical Supply; H. J. Harkins Company; Physicians Total Care; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Hydrochloric acid; Fd&c blue no. 2; Fd&c yellow no. 6; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Stearic acid; Fd&c blue no. 1; Glyceryl dibehenate; Magnesium stearate; Mannitol; Ammonium chloride; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Stearic acid; Fd&c blue no. 1; Glyceryl dibehenate; Magnesium stearate; Mannitol; Ammonium chloride; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Hydrochloric acid; Fd&c blue no. 2; Fd&c yellow no. 6; Titanium dioxide; Triacetin; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; Mylan Pharamceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Hydrochloric acid; Fd&c blue no. 2; Fd&c yellow no. 6; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 15 |
DFM Info
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Saccharin; Stearic acid; Anhydrous lactose; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Silicon dioxide; Hydroxypropyl cellulose (type h)
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Aidarex Pharmaceuticals; Proficient Rx; RemedyRepack; Sun Pharmaceutical Industries; TYA Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Benzosulfimide | DIG Info | Carbonic anhydrase VII (Ki = 10 nM) | [2] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 16 |
DFM Info
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Saccharin; Stearic acid; Anhydrous lactose; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Silicon dioxide; Hydroxypropyl cellulose
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Dispensing Solution | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Benzosulfimide | DIG Info | Carbonic anhydrase VII (Ki = 10 nM) | [2] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 17 |
DFM Info
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Hydrochloric acid; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol, unspecified
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|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; Cipla | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 18 |
DFM Info
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Saccharin; Stearic acid; Anhydrous lactose; Talc; Titanium dioxide; Polyethylene glycol 3350; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Benzosulfimide | DIG Info | Carbonic anhydrase VII (Ki = 10 nM) | [2] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 19 |
DFM Info
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Fd&c red no. 40; Fd&c yellow no. 6; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polydextrose; Polyethylene glycols
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|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 20 |
DFM Info
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Fd&c red no. 40; Fd&c yellow no. 6; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polydextrose; Polyethylene glycol
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| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Hydrochloric acid; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polyethylene glycol
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|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack; Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 22 |
DFM Info
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Stearic acid; Lactose monohydrate; Hydrochloric acid; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Polyethylene glycols
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|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging; Aphena Pharma Solutions-Tennessee; Bryant Ranch Prepack; Golden State Medical Supply; NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 23 |
DFM Info
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Stearic acid; Lactose monohydrate; Hydrochloric acid; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polyethylene glycols
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|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 24 |
DFM Info
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Stearic acid; Fd&c red no. 40; Fd&c blue no. 2; Potassium chloride; Titanium dioxide; Triethyl citrate; Hypromellose 2910 (15 mpa.s); Microcrystalline cellulose; Starch, corn
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| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [13] | |||
| Drug Formulation 25 |
DFM Info
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Stearic acid; Fd&c red no. 40; Fd&c blue no. 2; Potassium chloride; Titanium dioxide; Triethyl citrate; Cellulose, microcrystalline; Hypromellose 2910 (15 cps); Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [13] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Stearic acid; Fd&c red no. 40; Fd&c blue no. 2; Potassium chloride; Titanium dioxide; Triethyl citrate; Cellulose, microcrystalline; Hypromellose 2910 (15 mpa.s); Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; American Health Packaging; Aphena Pharma Solutions-Tennessee; BluePoint Laboratories; Bryant Ranch Prepack; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Major Pharmaceuticals; NuCare Pharmaceuticals; Rebel Distributors; RemedyRepack; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [13] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Stearic acid; Fd&c red no. 40; Fd&c blue no. 2; Potassium chloride; Titanium dioxide; Triethyl citrate; Cellulose, microcrystalline; Hypromellose 2910 (15 cps); Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [13] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Stearic acid; Fd&c red no. 40; Potassium chloride; Titanium dioxide; Triacetin; Polysorbate 80; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Heritage Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [13] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Stearic acid; Fd&c red no. 40; Fd&c blue no. 2; Potassium chloride; Titanium dioxide; Triethyl citrate; Hypromellose 2910 (15 mpa.s); Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Bryant Ranch Prepack; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [13] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Cysteine hydrochloride; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 6000; Cellulose, microcrystalline; Hypromellose 2910 (4000 mpa.s); Hypromellose 2910 (6 mpa.s)
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| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Cysteine hydrochloride | DIG Info | ABHD5-Perilipin complex (IC50 = 7335 nM) | [14] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Copovidone; Hydroxypropyl cellulose; Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Copovidone; Hydroxypropyl cellulose; Hypromelloses; Polydextrose; Polyethylene glycol
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| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Actavis South Atlantic | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Copovidone; Hydroxypropyl cellulose; Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Copovidone k25-31; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 35 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Copovidone k25-31; Hydroxypropyl cellulose; Hypromelloses; Polydextrose; Polyethylene glycol
|
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| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 36 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Copovidone k25-31; Hydroxypropyl cellulose; Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging; NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Fumaric acid; D&c red no. 7; Magnesium stearate; Titanium dioxide; Crospovidone; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Methylcellulose (100 mpa.s); Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [15] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 38 |
DFM Info
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|||||
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Fumaric acid; D&c red no. 7; Magnesium stearate; Titanium dioxide; Crospovidone; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Methylcellulose (100 cps); Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex; Contract Pharmacal; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [15] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 39 |
DFM Info
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|||||
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Fumaric acid; D&c red no. 7; Magnesium stearate; Titanium dioxide; Crospovidone; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Methylcellulose (100 mpa.s); Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [15] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 40 |
DFM Info
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|||||
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Cysteine hydrochloride; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | GlaxoSmithKline; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Cysteine hydrochloride | DIG Info | ABHD5-Perilipin complex (IC50 = 7335 nM) | [14] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 41 |
DFM Info
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|||||
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Cysteine hydrochloride; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Polysorbate 80; Cellulose, microcrystalline; Copovidone; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; ScieGen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Cysteine hydrochloride | DIG Info | ABHD5-Perilipin complex (IC50 = 7335 nM) | [14] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 42 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Hydrochloric acid; Magnesium stearate; Titanium dioxide; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydroxypropyl cellulose (type h); Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 43 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Hydrochloric acid; Magnesium stearate; Titanium dioxide; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydroxypropyl cellulose; Polyethylene glycol
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Kaiser Foundation Hospitals; Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 44 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (200000 mw); Hydroxypropyl cellulose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 45 |
DFM Info
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|||||
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Fumaric acid; D&c red no. 7; Magnesium stearate; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (type h); Hypromelloses; Methylcellulose (100 mpa.s); Polyethylene glycols
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | BluePoint Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [15] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 46 |
DFM Info
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|||||
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Fumaric acid; D&c red no. 7; Magnesium stearate; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (type h); Hypromelloses; Methylcellulose (100 cps); Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | AvPAK | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [15] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 47 |
DFM Info
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|||||
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Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Eon Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 48 |
DFM Info
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|||||
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Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Aphena Pharma Solutions-Tennessee; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 49 |
DFM Info
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|||||
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Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 50 |
DFM Info
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|||||
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Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 51 |
DFM Info
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|||||
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Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 52 |
DFM Info
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|||||
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Fd&c blue no. 2; Glyceryl dibehenate; Magnesium stearate; Talc; Titanium dioxide; Copovidone k25-31; Hydroxypropyl cellulose (1200000 mw); Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 53 |
DFM Info
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|||||
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Fd&c red no. 40; Fd&c yellow no. 6; Talc; Titanium dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Drug Formulation 54 |
DFM Info
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|||||
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Fd&c red no. 40; Fd&c yellow no. 6; Talc; Titanium dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Bupropion 200 mg tablet | Click to Show/Hide the Full List of Formulation(s): 22 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Mannitol; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Polyethylene glycol 3350; Polyethylene glycol 400; Polyvinyl alcohol; Hydrogenated castor oil; Hypromelloses; Povidones
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Jubilant Cadista Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Fd&c red no. 40; Hydrochloric acid; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Povidone; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Hydrogenated cottonseed oil; Hydroxypropyl cellulose
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Fd&c red no. 40; Hydrochloric acid; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Povidone; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Hydrogenated cottonseed oil; Hydroxypropyl cellulose
|
|||||
| Dosage Form | 12 HR Extended Release Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Stearic acid; Fd&c red no. 40; Glyceryl dibehenate; Magnesium stearate; Mannitol; Ammonium chloride; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Stearic acid; Fd&c red no. 40; Glyceryl dibehenate; Magnesium stearate; Mannitol; Ammonium chloride; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Saccharin; Stearic acid; Anhydrous lactose; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Silicon dioxide; Hydroxypropyl cellulose (type h)
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Proficient Rx; Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Benzosulfimide | DIG Info | Carbonic anhydrase VII (Ki = 10 nM) | [2] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Saccharin; Stearic acid; Anhydrous lactose; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Silicon dioxide; Hydroxypropyl cellulose
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Benzosulfimide | DIG Info | Carbonic anhydrase VII (Ki = 10 nM) | [2] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 8 |
DFM Info
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Fd&c red no. 40; Hydrochloric acid; Magnesium stearate; Titanium dioxide; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Cipla | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Hydrochloric acid; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Golden State Medical Supply; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Fd&c red no. 40; Cysteine hydrochloride; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 6000; Cellulose, microcrystalline; Hypromellose 2910 (4000 mpa.s); Hypromellose 2910 (6 mpa.s)
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Cysteine hydrochloride | DIG Info | ABHD5-Perilipin complex (IC50 = 7335 nM) | [14] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Fd&c red no. 40; Cysteine hydrochloride; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Cysteine hydrochloride | DIG Info | ABHD5-Perilipin complex (IC50 = 7335 nM) | [14] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Fd&c red no. 40; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Hydroxypropyl cellulose (120000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
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|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Eon Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Fd&c red no. 40; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Fd&c red no. 40; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polysorbate 80; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycol
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|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Fd&c red no. 40; Cysteine hydrochloride; Magnesium stearate; Titanium dioxide; Polysorbate 80; Cellulose, microcrystalline; Copovidone; Hypromelloses; Polyethylene glycols
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|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; ScieGen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Cysteine hydrochloride | DIG Info | ABHD5-Perilipin complex (IC50 = 7335 nM) | [14] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 16 |
DFM Info
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Stearic acid; Lactose monohydrate; Hydrochloric acid; Magnesium stearate; Titanium dioxide; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydroxypropyl cellulose; Polyethylene glycol
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|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (200000 mw); Hydroxypropyl cellulose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (50 mpa.s); Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (50 mpa.s); Hypromellose 2910 (6 mpa.s); Polydextrose; Polyethylene glycols
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|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Impax Generics; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Copovidone; Hydroxypropyl cellulose; Hypromelloses; Polydextrose; Polyethylene glycol
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|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Actavis South Atlantic | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Copovidone k25-31; Hydroxypropyl cellulose; Hypromelloses; Polydextrose; Polyethylene glycol
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|||||
| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Copovidone k25-31; Hydroxypropyl cellulose (1200000 mw); Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
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| Dosage Form | 12 HR Extended Release Oral Tablet | |||||
| Company | Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Bupropion 75 mg tablet | Click to Show/Hide the Full List of Formulation(s): 18 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Glutamic acid hydrochloride; D&c yellow no. 10; Maleic acid; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Hypromellose; Polyethylene glycol 400; Polyethylene glycol 6000; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydroxypropyl cellulose
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| Dosage Form | Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Glutamic acid hydrochloride | DIG Info | Glutamate receptor mGLU8 (IC50 = 5.7 nM) | [10] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Maleic acid | DIG Info | D-amino acid oxidase (IC50 = 357000 nM) | [11] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Glutamic acid hydrochloride; D&c yellow no. 10; Maleic acid; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Glutamic acid hydrochloride | DIG Info | Glutamate receptor mGLU8 (IC50 = 5.7 nM) | [10] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Maleic acid | DIG Info | D-amino acid oxidase (IC50 = 357000 nM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Hydrochloric acid; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Triacetin; Crospovidone; Hypromellose; Silicon dioxide; Cellulose, microcrystalline; Polydextrose; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Stearic acid; D&c yellow no. 10; Fd&c yellow no. 6; Potassium chloride; Titanium dioxide; Triacetin; Polysorbate 80; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Heritage Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [13] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Fumaric acid; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Crospovidone; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Methylcellulose (100 cps); Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex; Contract Pharmacal; NuCare Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [15] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Fumaric acid; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Crospovidone; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Methylcellulose (100 mpa.s); Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [15] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Hydrochloric acid; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (100 mpa.s); Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Hydrochloric acid; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Golden State Medical Supply; Physicians Total Care; RemedyRepack; Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 9 |
DFM Info
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Stearic acid; Fd&c red no. 40; Fd&c blue no. 2; Potassium chloride; Titanium dioxide; Triethyl citrate; Cellulose, microcrystalline; Hypromellose 2910 (15 cps); Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [13] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Stearic acid; Fd&c red no. 40; Fd&c blue no. 2; Potassium chloride; Titanium dioxide; Triethyl citrate; Cellulose, microcrystalline; Hypromellose 2910 (15 mpa.s); Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; American Health Packaging; Aphena Pharma Solutions-Tennessee; BluePoint Laboratories; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Major Pharmaceuticals; McKesson; Proficient Rx; Rebel Distributors; RemedyRepack; Sandoz; TYA Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [13] | |||
| Drug Formulation 11 |
DFM Info
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Stearic acid; Fd&c red no. 40; Fd&c blue no. 2; Potassium chloride; Titanium dioxide; Triethyl citrate; Cellulose, microcrystalline; Hypromellose 2910 (15 cps); Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal; Kaiser Foundation Hospitals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [13] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Stearic acid; Fd&c red no. 40; Fd&c blue no. 2; Potassium chloride; Titanium dioxide; Triethyl citrate; Cellulose, microcrystalline; Hypromellose 2910 (15 mpa.s); Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [13] | |||
| Drug Formulation 13 |
DFM Info
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Fumaric acid; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Methylcellulose (100 mpa.s); Polyethylene glycol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [15] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Fumaric acid; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (type h); Hypromelloses; Methylcellulose (100 mpa.s); Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | BluePoint Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [15] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 15 |
DFM Info
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Fumaric acid; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (type h); Hypromelloses; Methylcellulose (100 cps); Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | AvPAK | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [15] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 16 |
DFM Info
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Stearic acid; Anhydrous lactose; Hydrochloric acid; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Cardinal Health; Mylan Pharamceuticals; PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 17 |
DFM Info
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D&c yellow no. 10; Fd&c yellow no. 6; Talc; Titanium dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Drug Formulation 18 |
DFM Info
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D&c yellow no. 10; Fd&c yellow no. 6; Talc; Titanium dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Bupropion 300 mg tablet | Click to Show/Hide the Full List of Formulation(s): 33 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Stearic acid; Hydrochloric acid; Magnesium stearate; Mannitol; Ferrosoferric oxide; Propylene glycol; Talc; Triethyl citrate; Polysorbate 80; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Stearic acid; Hydrochloric acid; Magnesium stearate; Mannitol; Ferrosoferric oxide; Propylene glycol; Talc; Triethyl citrate; Polysorbate 80; Silicon dioxide; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Povidone, unspecified
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
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Sodium lauryl sulfate; Hydrochloric acid; Magnesium stearate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Water; Polyvinyl alcohol; Silicon dioxide; Copovidone k25-31; Hydroxypropyl cellulose (type h); Methacrylic acid; Polyethylene glycols; Povidones
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis South Atlantic; McKesson; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Sodium lauryl sulfate; Hydrochloric acid; Magnesium stearate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Povidone; Silicon dioxide; Copovidone; Hydroxypropyl cellulose (type h); Methacrylic acid; Polyethylene glycols; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 5 |
DFM Info
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Sodium lauryl sulfate; Hydrochloric acid; Magnesium stearate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Polyvinyl alcohol; Silicon dioxide; Copovidone k25-31; Hydroxypropyl cellulose (type h); Methacrylic acid; Polyethylene glycols; Povidones
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Triethyl citrate; Water; Povidone; Silicon dioxide; Ethylcelluloses; Hypromelloses; Methacrylic acid; Methyl alcohol; Polyethylene glycols; Shellac
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Triethyl citrate; Povidone; Silicon dioxide; Ethylcelluloses; Hypromelloses; Methacrylic acid; Polyethylene glycols; Shellac
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 8 |
DFM Info
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Sodium stearyl fumarate; Cysteine hydrochloride; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Butyl acrylate/c16-c20 alkyl methacrylate/methacrylic acid/methyl methacrylate copolymer; Ethylcelluloses; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Povidones; Shellac
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Jubilant Cadista Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Cysteine hydrochloride | DIG Info | ABHD5-Perilipin complex (IC50 = 7335 nM) | [14] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [16] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Sodium lauryl sulfate; Hydrochloric acid; Magnesium stearate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Copovidone; Hydroxypropyl cellulose (1200000 mw); Methacrylic acid; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Povidone, unspecified
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Sodium lauryl sulfate; Hydrochloric acid; Magnesium stearate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Copovidone k25-31; Hydroxypropyl cellulose (1200000 mw); Methacrylic acid; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Povidone, unspecified
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Cysteine hydrochloride; Dibutyl sebacate; Ammonia; Ferrosoferric oxide; Propylene glycol; Triethyl citrate; Povidone; Silicon dioxide; Ethylcelluloses; Glyceryl behenate/eicosadioate; Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyvinyl alcohol, unspecified; Shellac; Silica dimethyl silylate
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Lupin Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Cysteine hydrochloride | DIG Info | ABHD5-Perilipin complex (IC50 = 7335 nM) | [14] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Triethyl citrate; Silicon dioxide; Ethylcellulose, unspecified; Hypromellose, unspecified; Methacrylic acid; Polyethylene glycol, unspecified; Povidone, unspecified; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Triethyl citrate; Silicon dioxide; Ethylcelluloses; Hypromelloses; Methacrylic acid; Polyethylene glycols; Povidones; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | BluePoint Laboratories; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c red no. 40; Fd&c yellow no. 5; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Hydrochloric acid; Magnesium stearate; Talc; Triethyl citrate; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Copovidone; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; ScieGen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Hydrochloric acid; Isopropyl alcohol; Povidone; Silicon dioxide; Alcohol; Ethylcelluloses; Hydrogenated cottonseed oil; Hydroxypropyl cellulose (type h); Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals; Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Hydrochloric acid; Isopropyl alcohol; Povidone; Silicon dioxide; Alcohol; Ethylcelluloses; Hydrogenated cottonseed oil; Hydroxypropyl cellulose; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Citric acid monohydrate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | BluePoint Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Citric acid monohydrate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Cipla; Exelan Pharmaceuticals; Preferred Pharamaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Stearic acid; Hydrochloric acid; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Ethylcellulose; Hydroxypropyl cellulose; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Stearic acid; Hydrochloric acid; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hydroxypropyl cellulose (type h); Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Stearic acid; Hydrochloric acid; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hydroxypropyl cellulose; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Hydrochloric acid; Isopropyl alcohol; Silicon dioxide; Alcohol; Ethylcellulose, unspecified; Hydrogenated cottonseed oil; Hydroxypropyl cellulose (1200000 mw); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Hydrochloric acid; Isopropyl alcohol; Silicon dioxide; Alcohol; Ethylcellulose, unspecified; Hydrogenated cottonseed oil; Hydroxypropyl cellulose (1200000 mw); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Hydrochloric acid; Isopropyl alcohol; Silicon dioxide; Alcohol; Ethylcelluloses; Hydrogenated cottonseed oil; Hydroxypropyl cellulose (type h); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Aidarex Pharmaceuticals; AvKARE; AvPAK; Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Stearic acid; Hydrochloric acid; Talc; Titanium dioxide; Triethyl citrate; Cellulose, microcrystalline; Colloidal silicon dioxide; Ethylcelluloses; Hydroxypropyl cellulose; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Stearic acid; Hydrochloric acid; Talc; Titanium dioxide; Triethyl citrate; Cellulose, microcrystalline; Colloidal silicon dioxide; Ethylcellulose; Hydroxypropyl cellulose; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Stearic acid; Hydrochloric acid; Talc; Titanium dioxide; Triethyl citrate; Cellulose, microcrystalline; Colloidal silicon dioxide; Ethylcelluloses; Hydroxypropyl cellulose; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dispensing Solution | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Glyceryl behenate; Triethyl citrate; Polyvinyl alcohol; Povidone; Silicon dioxide; Ethylcelluloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Glyceryl behenate; Triethyl citrate; Polyvinyl alcohol; Povidone; Silicon dioxide; Ethylcelluloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Glyceryl behenate; Triethyl citrate; Polyvinyl alcohol; Povidone; Silicon dioxide; Ethylcelluloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Tablet | |||||
| Company | BTA Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Glyceryl dibehenate; Triethyl citrate; Silicon dioxide; Ethylcellulose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack; Valeant Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Glyceryl dibehenate; Silicon dioxide; Copovidone; Ethylcelluloses; Hydroxypropyl cellulose (type h); Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Epic Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Bupropion 450 mg tablet | Click to Show/Hide the Full List of Formulation(s): 2 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Stearic acid; Hydrochloric acid; Magnesium stearate; Talc; Titanium dioxide; Triacetin; Silicon dioxide; Carboxymethylcellulose sodium, unspecified form; Copovidone k25-31; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol 8000; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Edgemont Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Stearic acid; Hydrochloric acid; Magnesium stearate; Talc; Titanium dioxide; Triacetin; Silicon dioxide; Carboxymethylcellulose sodium, unspecified form; Copovidone k25-31; Hydroxypropyl cellulose (type h); Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol 8000; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Almatica Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [12] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Bupropion Hydrochloride 100mg extended release tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Carnauba Wax; Cysteine Hydrochloride; Hypromellose; Magnesium Stearate; Microcrystalline Cellulose; Polyethylene Glycol; Polysorbate 80; Titanium Dioxide Edible Black Ink; Fd&C Blue No 2 Lake; Fd&C Red No 40 Lake
|
|||||
| Dosage Form | Extended Release Tablet | |||||
| Company | Glaxosmithkline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Cysteine hydrochloride | DIG Info | ABHD5-Perilipin complex (IC50 = 7335 nM) | [14] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Bupropion Hydrochloride 50mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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D&C Yellow No 10 Lake; Fd&C Yellow No 6 Lake; Hydroxypropyl Cellulose; Hypromellose; Microcrystalline Cellulose; Polyethylene Glycol; Talc; Titanium Dioxide; Fd&C Red No 40 Lake
|
|||||
| Dosage Form | Tablet | |||||
| Company | Glaxosmithkline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Hydroxypropyl cellulose | DIG Info | Mephenytoin 4-hydroxylase (EC50 = 89.5 uM) | [7] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Bupropion 348 mg tablet | Click to Show/Hide the Full List of Formulation(s): 2 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|
|||||
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Dibutyl sebacate; Glyceryl behenate; Polyvinyl alcohol; Povidone; Carnauba wax; Ethylcellulose (100 mpa.s); Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Dibutyl sebacate; Glyceryl dibehenate; Carnauba wax; Crospovidone, unspecified; Ethylcellulose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Valeant Pharmaceuticals | |||||
| Bupropion 522 mg tablet | Click to Show/Hide the Full List of Formulation(s): 2 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Dibutyl sebacate; Glyceryl dibehenate; Polyvinyl alcohol; Ethylcellulose (100 mpa.s); Polyethylene glycols; Povidones
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Sanofi-Aventis | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Drug Formulation 2 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Dibutyl sebacate; Glyceryl dibehenate; Crospovidone, unspecified; Ethylcellulose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Valeant Pharmaceuticals | |||||
| Bupropion 174 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
click to show the detail info of this DFM
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Dibutyl sebacate; Glyceryl dibehenate; Carnauba wax; Ethylcellulose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Povidone, unspecified
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Valeant Pharmaceuticals | |||||
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