Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00508) | |||||
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| Name |
Pantoprazole
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| Synonyms |
Click to Show/Hide the Synonyms of This API
pantoprazole; 102625-70-7; Protonix; Pantozol; Pantoprazol; Pantoprazolum; BY-1023; Pantoloc; SK&F-96022; BY 1023; SK&F 96022; Protonix I.V.; Pantozol Control; SK-96022; CHEMBL1502; CHEBI:7915; Pantoprazole sodium hydrate; NCGC00095188-01; Pantoprazol [INN-Spanish]; Pantoprazolum [INN-Latin]; DSSTox_CID_3416; Controloc Control; DSSTox_RID_77019; DSSTox_GSID_23416; (R)-Pantoprazole; Panyocid; C16H15F2N3O4S; apo-Pantoprazole; Somac Control; Pantecta Control; Pantoloc Control; PANTOPRAZOLE SODIUM SALT; SKF-96022; CAS-102625-70-7; HSDB 7292; Pantoprazole (USAN/INN); Pantoprazole [USAN:INN:BAN]; 5-(Difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridyl)methyl)sulfinyl)benzimidazole; Pantoprazole (Protonix); Pantoprazole-d6 (Rac); EC 600-331-6; SCHEMBL29465; BSPBio_002320; MLS003882559; BIDD:GT0003; SPECTRUM1505818; GTPL7260; DTXSID4023416; HMS1922H20; HMS2090H03; HMS2093F14; Pharmakon1600-01505818; BCP20279; BCP21400; Tox21_111477; AC-679; BDBM50241342; MFCD00870182; NSC759257; STL451032; AKOS015894910; AKOS034831879; Tox21_111477_1; CCG-213558; CCG-268437; CS-3161; DB00213; MCULE-8988409059; NSC-759257; SB17368; 6-(difluoromethoxy)-2-[(3,4-dimethoxy-2-pyridyl)methylsulfinyl]-1H-benzimidazole; NCGC00095188-02; NCGC00095188-03; NCGC00095188-04; NCGC00095188-05; NCGC00389443-01; BS-14224; HY-17507; SMR002533625; SBI-0206873.P001; AB0012612; FT-0602547; C11806; D05353; W-1227; AB01275513-01; AB01275513_02; 625P707; A800593; Q286846; SR-01000763715; J-000744; SR-01000763715-3; 5-(difluoromethoxy)-2-((3,4-dimethoxypyridin-2-yl); BRD-A22380646-001-01-5; BRD-A22380646-001-02-3; (R)-(+)-Pantoprazole;(+)-(R)-Pantoprazole;Pantoprazole Isomer(R) Impurity; 2-(((3,4-Dimethoxy-2-pyridinyl)methyl)-sulfinyl)-5-methyl-1H-1,3-benzimidazole; 5-(difluoromethoxy)-2-[(3,4-dimethoxy-2-pyridyl)methylsulfinyl]-1H-benzimidazole; 5-Difluoromethoxy-2-[(3,4-dimethoxy-2-pyridyl)methylsulfinyl]-1H-benzimidazole
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| Clinical Status |
Approved
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| Disease Indication | Gastro-oesophageal reflux disease | ICD-11: DA22 | [1] | ||
| PubChem CID | |||||
| Formula |
C16H15F2N3O4S
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| Canonical SMILES |
COC1=C(C(=NC=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC(F)F)OC
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| InChI |
1S/C16H15F2N3O4S/c1-23-13-5-6-19-12(14(13)24-2)8-26(22)16-20-10-4-3-9(25-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21)
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| InChIKey |
IQPSEEYGBUAQFF-UHFFFAOYSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 383.4 | Topological Polar Surface Area | 106 | |
| XlogP | 2.4 | Complexity | 490 | ||
| Heavy Atom Count | 26 | Rotatable Bond Count | 7 | ||
| Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 9 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
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| Pantoprazole 20 mg tablet | Click to Show/Hide the Full List of Formulation(s): 38 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Calcium stearate; Fd&c blue no. 2; Mannitol; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Sodium hydroxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Polyethylene glycol 4000; Polyethylene glycol 6000; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals; RemedyRepack; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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Calcium stearate; Fd&c blue no. 2; Mannitol; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Sodium hydroxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Polyethylene glycol 4000; Polyethylene glycol 6000; Colloidal silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; St Marys Medical Park Pharmacy; Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Drug Formulation 3 |
DFM Info
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Stearic acid; Lactose monohydrate; Calcium carbonate; D&c yellow no. 10; Calcium stearate; Fd&c yellow no. 6; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 4000; Aluminum oxide; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | AvKARE; Medsource Pharmaceuticals; NCS HealthCare of KY, Inc dba Vangard Labs; NuCare Pharmaceuticals; Physicians Total Care; Proficient Rx; RxChange | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [6] | |||
| Calcium carbonate | DIG Info | Carbonic anhydrase IX (Ki = 8600 nM) | [8] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
| Drug Formulation 4 |
DFM Info
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Stearic acid; Lactose monohydrate; Calcium carbonate; D&c yellow no. 10; Calcium stearate; Fd&c yellow no. 6; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 4000; Aluminum oxide; Hypromellose 2910 (15 mpa.s); Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [6] | |||
| Calcium carbonate | DIG Info | Carbonic anhydrase IX (Ki = 8600 nM) | [8] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
| Drug Formulation 5 |
DFM Info
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Stearic acid; Lactose monohydrate; Calcium carbonate; D&c yellow no. 10; Calcium stearate; Fd&c yellow no. 6; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 4000; Hypromellose 2910 (15 mpa.s); Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | A-S Medication Solutions; RemedyRepack; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [6] | |||
| Calcium carbonate | DIG Info | Carbonic anhydrase IX (Ki = 8600 nM) | [8] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
| Drug Formulation 6 |
DFM Info
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Stearic acid; Lactose monohydrate; Calcium carbonate; D&c yellow no. 10; Calcium stearate; Fd&c yellow no. 6; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 4000; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [6] | |||
| Calcium carbonate | DIG Info | Carbonic anhydrase IX (Ki = 8600 nM) | [8] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
| Drug Formulation 7 |
DFM Info
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Sodium lauryl sulfate; Calcium stearate; Mannitol; Ferric oxide yellow; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone; Hypromellose; Polysorbate 80; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone k25; Povidone k90
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 8 |
DFM Info
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Anhydrous lactose; Butyl alcohol; Calcium stearate; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Povidone; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 9 |
DFM Info
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Butyl alcohol; Calcium stearate; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Polyethylene glycol 400; Alcohol; Hydroxypropyl cellulose (type h); Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Zein
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 10 |
DFM Info
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Calcium stearate; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Isobutyl alcohol; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Polyethylene glycol 6000; Hydroxypropyl cellulose (type e); Hypromellose 2910 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | OrchidPharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Drug Formulation 11 |
DFM Info
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Butyl alcohol; Calcium stearate; Isopropyl alcohol; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone; Povidone; Alcohol; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Macleods Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 12 |
DFM Info
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Sodium lauryl sulfate; Calcium stearate; Mannitol; Ferric oxide yellow; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone; Polysorbate 80; Hypromellose 2208 (100 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone k25; Povidone k90
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 13 |
DFM Info
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Sodium lauryl sulfate; Calcium stearate; Mannitol; Ferric oxide yellow; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone; Polysorbate 80; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone k25; Povidone k90
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Physicians Total Care; Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 14 |
DFM Info
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Sodium stearyl fumarate; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Sodium hydroxide; Talc; Titanium dioxide; Triethyl citrate; Povidone; Crospovidone (12 mpa.s at 5%); Hydroxypropyl cellulose, low substituted; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Polyvinyl alcohol, unspecified; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Amneal Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [10] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Drug Formulation 15 |
DFM Info
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Sodium lauryl sulfate; Calcium stearate; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Hypromelloses; Methacrylic acid; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Actavis Inc.; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 16 |
DFM Info
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Butyl alcohol; Calcium stearate; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Triethyl citrate; Crospovidone; Hydroxypropyl cellulose; Hypromellose 2910 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 17 |
DFM Info
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Butyl alcohol; Calcium stearate; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Triethyl citrate; Crospovidone; Hydroxypropyl cellulose (type l); Hypromellose 2910 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Aurobindo Pharma; Avera McKennan Hospital; Prasco | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 18 |
DFM Info
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Sodium lauryl sulfate; Calcium stearate; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 19 |
DFM Info
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Sodium lauryl sulfate; Calcium stearate; Mannitol; Ferric oxide yellow; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Polysorbate 80; Crospovidone (15 mpa.s at 5%); Hypromellose 2208 (100 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone k25; Povidone k90
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Pfizer | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 20 |
DFM Info
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Sodium lauryl sulfate; Calcium stearate; Mannitol; Ferric oxide yellow; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Polysorbate 80; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone k25; Povidone k90
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health; Pfizer | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 21 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Calcium stearate; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Polysorbate 80; Hydroxypropyl cellulose (type h); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Camber Pharmaceuticals; NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 22 |
DFM Info
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Sodium stearyl fumarate; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Sodium hydroxide; Talc; Titanium dioxide; Triethyl citrate; Crospovidone (12 mpa.s at 5%); Crospovidone, unspecified; Hypromellose, unspecified; Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [10] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Drug Formulation 23 |
DFM Info
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Butyl alcohol; Calcium stearate; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Triethyl citrate; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (type h); Hypromellose 2910 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Drug Formulation 24 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Calcium stearate; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Polysorbate 80; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Proficient Rx; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 25 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Calcium stearate; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Polysorbate 80; Hydroxypropyl cellulose (type h); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 26 |
DFM Info
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Calcium stearate; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health; Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 27 |
DFM Info
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Calcium stearate; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 28 |
DFM Info
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Calcium stearate; Mannitol; Ferric oxide red; Propylene glycol; Sodium carbonate; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 29 |
DFM Info
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Calcium stearate; Mannitol; Ferric oxide red; Propylene glycol; Sodium carbonate; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Shellac
|
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Calcium stearate; Mannitol; Ferric oxide red; Propylene glycol; Sodium carbonate; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac
|
|||||
| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | DirectRX; Jubilant Cadista Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 31 |
DFM Info
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Lactose monohydrate; Glyceryl dibehenate; Isopropyl alcohol; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1)
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Aphena Pharma Solutions-Tennessee; AvPAK; Lannett Company; NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 32 |
DFM Info
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Calcium stearate; Mannitol; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Hydroxypropyl cellulose (type h); Hypromellose 2910 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | NuCare Pharmaceuticals; RemedyRepack; St Marys Medical Park Pharmacy; State of Florida DOH Central Pharmacy; Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 33 |
DFM Info
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Calcium stearate; Mannitol; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Hydroxypropyl cellulose; Hypromellose 2910 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 34 |
DFM Info
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Lactose monohydrate; Glyceryl dibehenate; Isopropyl alcohol; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1)
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Drug Formulation 35 |
DFM Info
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Calcium stearate; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Drug Formulation 36 |
DFM Info
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|||||
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Lactose monohydrate; Glyceryl dibehenate; Isopropyl alcohol; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Crospovidone (15 mpa.s at 5%); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1)
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Mannitol; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (type h); Hypromellose 2910 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Drug Formulation 38 |
DFM Info
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Calcium stearate; Fd&c blue no. 2; Propylene glycol 1,2-distearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Sodium hydroxide; Talc; Titanium dioxide; Triethyl citrate; Colloidal silicon dioxide; Hypromelloses; Mannitol hexanitrate; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol 4000000; Polyethylene glycol 600000; Shellac; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Pantoprazole 40 mg tablet | Click to Show/Hide the Full List of Formulation(s): 56 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Calcium stearate; Fd&c blue no. 2; Mannitol; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Sodium hydroxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Polyethylene glycol 4000; Polyethylene glycol 6000; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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Calcium stearate; Fd&c blue no. 2; Mannitol; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Sodium hydroxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Polyethylene glycol 4000; Polyethylene glycol 6000; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Sodium starch glycolate type a potato; Starch, corn
|
|||||
| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 3 |
DFM Info
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Sodium lauryl sulfate; Calcium stearate; Mannitol; Ferric oxide yellow; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone; Hypromellose; Polysorbate 80; Povidone; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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Calcium stearate; Fd&c blue no. 2; Mannitol; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Sodium hydroxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Polyethylene glycol 4000; Polyethylene glycol 6000; Colloidal silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Drug Formulation 5 |
DFM Info
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Calcium stearate; Fd&c blue no. 2; Mannitol; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Sodium hydroxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Polyethylene glycol 4000; Polyethylene glycol 6000; Colloidal silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Drug Formulation 6 |
DFM Info
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Stearic acid; Lactose monohydrate; Calcium carbonate; D&c yellow no. 10; Calcium stearate; Fd&c yellow no. 6; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 4000; Aluminum oxide; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; AvKARE; Bryant Ranch Prepack; Clinical Solutions Wholesale; DirectRX; Lake Eire Medical & Surgical Supply DBA Quality Care Products; NCS HealthCare of KY, Inc dba Vangard Labs; Physicians Total Care; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [6] | |||
| Calcium carbonate | DIG Info | Carbonic anhydrase IX (Ki = 8600 nM) | [8] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
| Drug Formulation 7 |
DFM Info
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Stearic acid; Lactose monohydrate; Calcium carbonate; D&c yellow no. 10; Calcium stearate; Fd&c yellow no. 6; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 4000; Aluminum oxide; Hypromellose 2910 (15 mpa.s); Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [6] | |||
| Calcium carbonate | DIG Info | Carbonic anhydrase IX (Ki = 8600 nM) | [8] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
| Drug Formulation 8 |
DFM Info
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Stearic acid; Lactose monohydrate; Calcium carbonate; D&c yellow no. 10; Calcium stearate; Fd&c yellow no. 6; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Lecithin, soybean; Aluminum oxide; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [6] | |||
| Calcium carbonate | DIG Info | Carbonic anhydrase IX (Ki = 8600 nM) | [8] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [4] | |||
| Drug Formulation 9 |
DFM Info
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Stearic acid; Lactose monohydrate; Calcium carbonate; D&c yellow no. 10; Calcium stearate; Fd&c yellow no. 6; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 4000; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [6] | |||
| Calcium carbonate | DIG Info | Carbonic anhydrase IX (Ki = 8600 nM) | [8] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
| Drug Formulation 10 |
DFM Info
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Stearic acid; Lactose monohydrate; Calcium carbonate; D&c yellow no. 10; Calcium stearate; Fd&c yellow no. 6; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 4000; Hypromellose 2910 (15 mpa.s); Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Contract Pharmacal; RemedyRepack; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [6] | |||
| Calcium carbonate | DIG Info | Carbonic anhydrase IX (Ki = 8600 nM) | [8] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
| Drug Formulation 11 |
DFM Info
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Stearic acid; Lactose monohydrate; Calcium carbonate; D&c yellow no. 10; Calcium stearate; Fd&c yellow no. 6; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 4000; Aluminum oxide; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [6] | |||
| Calcium carbonate | DIG Info | Carbonic anhydrase IX (Ki = 8600 nM) | [8] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
| Drug Formulation 12 |
DFM Info
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Anhydrous lactose; Butyl alcohol; Calcium stearate; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Povidone; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 13 |
DFM Info
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Anhydrous lactose; Butyl alcohol; Calcium stearate; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Povidone; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | DirectRX; Lake Eire Medical & Surgical Supply DBA Quality Care Products; New Horizon Rx Group; Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 14 |
DFM Info
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Butyl alcohol; Calcium stearate; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Polyethylene glycol 400; Alcohol; Hydroxypropyl cellulose (type h); Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Zein
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 15 |
DFM Info
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Butyl alcohol; Calcium stearate; Isopropyl alcohol; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Polyethylene glycol 400; Alcohol; Hydroxypropyl cellulose (type h); Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Zein
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health; Legacy Pharmaceutical; Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 16 |
DFM Info
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Calcium stearate; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Isobutyl alcohol; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone; Polyethylene glycol 6000; Hydroxypropyl cellulose (type e); Hypromellose 2910 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | OrchidPharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Drug Formulation 17 |
DFM Info
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Butyl alcohol; Calcium stearate; Isopropyl alcohol; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone; Povidone; Alcohol; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Macleods Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 18 |
DFM Info
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Sodium lauryl sulfate; Calcium stearate; Mannitol; Ferric oxide yellow; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone; Polysorbate 80; Hypromellose 2208 (100 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone k25; Povidone k90
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Cardinal Health; St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 19 |
DFM Info
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Sodium lauryl sulfate; Calcium stearate; Mannitol; Ferric oxide yellow; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone; Polysorbate 80; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone k25; Povidone k90
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 20 |
DFM Info
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Sodium lauryl sulfate; Calcium stearate; Mannitol; Ferric oxide yellow; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone; Polysorbate 80; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone k25; Povidone k90
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Avera McKennan Hospital; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 21 |
DFM Info
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Sodium lauryl sulfate; Calcium stearate; Mannitol; Ferric oxide yellow; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone; Polysorbate 80; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone k25; Povidone k90
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 22 |
DFM Info
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Anhydrous lactose; Butyl alcohol; Calcium stearate; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones; Shellac
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|||||
| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 23 |
DFM Info
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Sodium stearyl fumarate; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Sodium hydroxide; Talc; Titanium dioxide; Triethyl citrate; Povidone; Crospovidone (12 mpa.s at 5%); Hydroxypropyl cellulose, low substituted; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Polyvinyl alcohol, unspecified; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Amneal Pharmaceuticals; Aphena Pharma Solutions-Tennessee; California Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [10] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Drug Formulation 24 |
DFM Info
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Sodium lauryl sulfate; Calcium stearate; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Hypromelloses; Methacrylic acid; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Actavis Inc.; Clinical Solutions Wholesale; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 25 |
DFM Info
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Sodium lauryl sulfate; Calcium stearate; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Hypromelloses; Methacrylic acid; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 26 |
DFM Info
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Butyl alcohol; Calcium stearate; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Triethyl citrate; Crospovidone; Hydroxypropyl cellulose (type l); Hypromellose 2910 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Aurobindo Pharma; Contract Pharmacal; PD-Rx Pharmaceuticals; Prasco; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 27 |
DFM Info
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Butyl alcohol; Calcium stearate; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Triethyl citrate; Crospovidone; Hydroxypropyl cellulose (type h); Hypromellose 2910 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Safecor Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 28 |
DFM Info
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Sodium lauryl sulfate; Calcium stearate; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 29 |
DFM Info
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Sodium lauryl sulfate; Calcium stearate; Mannitol; Ferric oxide yellow; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Polysorbate 80; Crospovidone (15 mpa.s at 5%); Hypromellose 2208 (100 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone k25; Povidone k90
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals; Pfizer | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 30 |
DFM Info
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Sodium lauryl sulfate; Calcium stearate; Mannitol; Ferric oxide yellow; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Polysorbate 80; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone k25; Povidone k90
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health; Pfizer | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 31 |
DFM Info
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Anhydrous lactose; Butyl alcohol; Calcium stearate; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Povidone, unspecified; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Drug Formulation 32 |
DFM Info
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Butyl alcohol; Calcium stearate; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Triethyl citrate; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (type l); Hypromellose 2910 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Drug Formulation 33 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Calcium stearate; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Polysorbate 80; Hydroxypropyl cellulose (type h); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Camber Pharmaceuticals; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 34 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Calcium stearate; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Polysorbate 80; Hydroxypropyl cellulose (type h); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [6] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 35 |
DFM Info
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Calcium stearate; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 36 |
DFM Info
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Calcium stearate; Mannitol; Ferric oxide red; Propylene glycol; Sodium carbonate; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Jubilant Cadista Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 37 |
DFM Info
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Calcium stearate; Mannitol; Ferric oxide red; Propylene glycol; Sodium carbonate; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 38 |
DFM Info
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Anhydrous lactose; Calcium stearate; Mannitol; Ferric oxide yellow; Sodium carbonate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Povidone; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health; Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 39 |
DFM Info
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Lactose monohydrate; Glyceryl dibehenate; Isopropyl alcohol; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1)
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | American Health Packaging; Aphena Pharma Solutions-Tennessee; AvPAK; Kremers Urban Pharmaceuticals Inc.; Legacy Pharmaceutical; McKesson; Raritan Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 40 |
DFM Info
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|||||
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Calcium stearate; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 41 |
DFM Info
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Lactose monohydrate; Glyceryl behenate; Isopropyl alcohol; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1)
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 42 |
DFM Info
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|||||
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Lactose monohydrate; Glyceryl dibehenate; Isopropyl alcohol; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1)
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 43 |
DFM Info
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|||||
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Calcium stearate; Mannitol; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Sodium carbonate decahydrate; Hydroxypropyl cellulose (80000 mw); Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Hydroxypropyl cellulose | DIG Info | Mephenytoin 4-hydroxylase (EC50 = 89.5 uM) | [7] | |||
| Drug Formulation 44 |
DFM Info
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|||||
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Calcium stearate; Mannitol; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Sodium carbonate decahydrate; Crospovidone; Hydroxypropyl cellulose (type e); Hypromellose 2910 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 45 |
DFM Info
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|||||
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Calcium stearate; Mannitol; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Sodium carbonate decahydrate; Crospovidone; Hydroxypropyl cellulose (type h); Hypromellose 2910 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | NuCare Pharmaceuticals; RemedyRepack; State of Florida DOH Central Pharmacy; Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 46 |
DFM Info
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Calcium stearate; Mannitol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Drug Formulation 47 |
DFM Info
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Calcium stearate; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Drug Formulation 48 |
DFM Info
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Calcium stearate; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium carbonate; Titanium dioxide; Triethyl citrate; Crospovidone, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Drug Formulation 49 |
DFM Info
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Lactose monohydrate; Glyceryl dibehenate; Isopropyl alcohol; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Crospovidone (15 mpa.s at 5%); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1)
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Legacy Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Drug Formulation 50 |
DFM Info
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Calcium stearate; Mannitol; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Sodium carbonate decahydrate; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (1200000 mw); Hypromellose 2910 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Drug Formulation 51 |
DFM Info
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|||||
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Lactose monohydrate; Glyceryl dibehenate; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1)
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 52 |
DFM Info
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|||||
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Lactose monohydrate; Glyceryl dibehenate; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1)
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 53 |
DFM Info
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|
|||||
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Lactose monohydrate; Glyceryl dibehenate; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1)
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Aphena Pharma Solutions-Tennessee; Lannett Company; Legacy Pharmaceutical; NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 54 |
DFM Info
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|||||
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Lactose monohydrate; Glyceryl dibehenate; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Crospovidone (19 mpa.s at 5%); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1)
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Legacy Pharmaceutical | |||||
| Drug Formulation 55 |
DFM Info
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|
|||||
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Lactose monohydrate; Glyceryl dibehenate; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Crospovidone, unspecified; Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1)
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Proficient Rx | |||||
| Drug Formulation 56 |
DFM Info
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|
|||||
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Lactose monohydrate; Glyceryl dibehenate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1)
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
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