Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00548) | |||||
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| Name |
Pravastatin
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| Synonyms |
Click to Show/Hide the Synonyms of This API
pravastatin; 81093-37-0; Pravastatina; Pravastatine; Pravastatinum; Pravachol; Pravastatin acid; PRAVASTATIN SODIUM; UNII-KXO2KT9N0G; (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid; KXO2KT9N0G; CHEMBL1144; (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid; Eptastatin; CHEBI:63618; Pravastatine [French]; Pravastatinum [Latin]; Pravastatina [Spanish]; Pravastatin [INN:BAN]; (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid; Mevalothin; Pravator (TN); (+)-(3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(S)-2-methylbutyryl]oxy}-1,2,6,7,8,8a-hexahydro-1-naphthyl]heptanoic acid; Pravastatin (INN); CCRIS 7557; C10AA03; 3beta-Hydroxycompactin; KS-5015; SCHEMBL1117; BIDD:GT0773; GTPL2953; DTXSID6023498; BDBM20688; HSDB 8368; HMS3715P11; ACT02637; HY-B0165; ZINC3798763; 1,4-Butanedisulfonicaciddisodiumsalt; LMFA05000695; AKOS015895229; CCG-221195; DB00175; NCGC00188962-01; NCGC00188962-02; 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, (1S-(1alpha(betaS*,deltaS*),2alpha,6alpha,8beta(R*),8aalpha))-1-Naphthaleneheptanoic acid; 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-((2S)-2-methyl-1-oxobutoxy)-, (betaR,deltaR,1S,2S,6S,8S,8aR)-; 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, (1S-(1alpha(betas*,deltas*),2alpha,6alpha,8beta(R*),8aalpha))-; C01844; D08410; 093P370; SR-01000781259; Q1240093; SR-01000781259-2; BRD-K60511616-236-01-4; BRD-K60511616-236-02-2; BRD-K60511616-236-08-9; (3R,5R)-3,5-dihydroxy-7-((1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-((S)-2-methylbutanoyloxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)heptanoic acid
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| Clinical Status |
Approved
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| Disease Indication | Dyslipidaemia | ICD-11: 5C81 | [1] | ||
| PubChem CID | |||||
| Formula |
C23H36O7
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| Canonical SMILES |
CC[C@H](C)C(=O)O[C@H]1C[C@@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)O)O)O)O
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| InChI |
1S/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/t13-,14-,16+,17+,18+,19-,20-,22-/m0/s1
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| InChIKey |
TUZYXOIXSAXUGO-PZAWKZKUSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=54687"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 424.5 | Topological Polar Surface Area | 124 | |
| XlogP | 1.6 | Complexity | 656 | ||
| Heavy Atom Count | 30 | Rotatable Bond Count | 11 | ||
| Hydrogen Bond Donor Count | 4 | Hydrogen Bond Acceptor Count | 7 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
|---|---|---|---|---|---|---|
| Pravastatin 40 mg tablet | Click to Show/Hide the Full List of Formulation(s): 32 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Mannitol; Meglumine; Crospovidone; Hypromellose; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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Lactose; D&c yellow no. 10; Sodium stearyl fumarate; Fd&c blue no. 1; Anhydrous dibasic calcium phosphate; Croscarmellose sodium; Crospovidone; Povidone; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Mannitol; Meglumine; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Mannitol; Meglumine; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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|
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D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Mannitol; Meglumine; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Blenheim Phamacal; Cardinal Health; NCS HealthCare of KY, Inc dba Vangard Labs; Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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|
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Anhydrous lactose; D&c yellow no. 10; Sodium stearyl fumarate; Fd&c blue no. 1; Croscarmellose sodium; Crospovidone; Povidone; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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|
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D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Mannitol; Meglumine; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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|
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Mannitol; Meglumine; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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|
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Magnesium oxide; Croscarmellose sodium; Povidone; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Accord Healthcare; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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|
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Anhydrous lactose; D&c yellow no. 10; Sodium stearyl fumarate; Fd&c blue no. 1; Anhydrous dibasic calcium phosphate; Croscarmellose sodium; Povidone k30; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%)
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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|
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Anhydrous lactose; D&c yellow no. 10; Sodium stearyl fumarate; Fd&c blue no. 1; Anhydrous dibasic calcium phosphate; Croscarmellose sodium; Povidone k30; Crospovidone (15 mpa.s at 5%); Microcrystalline cellulose
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 12 |
DFM Info
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|
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Anhydrous lactose; D&c yellow no. 10; Sodium stearyl fumarate; Fd&c blue no. 1; Croscarmellose sodium; Crospovidone; Povidone k30; Aluminum oxide; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; AvKARE; McKesson; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 13 |
DFM Info
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Lactose, unspecified form; D&c yellow no. 10; Sodium stearyl fumarate; Fd&c blue no. 1; Anhydrous dibasic calcium phosphate; Croscarmellose sodium; Crospovidone (15 mpa.s at 5%); Microcrystalline cellulose; Povidone, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 14 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Meglumine; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol 8000
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| Dosage Form | Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 15 |
DFM Info
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Lactose, unspecified form; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Aluminum hydroxide; Magnesium oxide; Croscarmellose sodium; Cellulose, microcrystalline; Povidones
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| Dosage Form | Oral Tablet | |||||
| Company | E.R. Squibb & Sons | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 16 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Croscarmellose sodium; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Povidones; Sodium phosphate, dibasic
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| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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Anhydrous lactose; D&c yellow no. 10; Sodium stearyl fumarate; Fd&c blue no. 1; Croscarmellose sodium; Povidone k30; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%)
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| Dosage Form | Oral Tablet | |||||
| Company | International Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 18 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Ferric oxide yellow; Croscarmellose sodium; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Ferric oxide yellow; Croscarmellose sodium; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Ferric oxide yellow; Croscarmellose sodium; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Aphena Pharma Solutions-Tennessee; Apotex; Clinical Solutions Wholesale; NuCare Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Calcium stearate; Mannitol; Ferric oxide yellow; Crospovidone; Hydroxypropyl cellulose, low substituted
|
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| Dosage Form | Oral Tablet | |||||
| Company | Cipla | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Sodium stearyl fumarate; Fd&c blue no. 1; Dihydroxyaluminum sodium carbonate
|
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Sodium bicarbonate; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Hypromellose 2910 (6 mpa.s); Polyethylene glycol 8000
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 24 |
DFM Info
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Anhydrous lactose; Magnesium stearate; Sodium carbonate; Croscarmellose sodium; Polyoxyl 35 castor oil; Cellulose, microcrystalline
|
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| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; American Health Packaging; Cadila Healthcare; Cardinal Health; PD-Rx Pharmaceuticals; Proficient Rx; St Marys Medical Park Pharmacy; State of Florida DOH Central Pharmacy; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyoxyl 35 castor oil | DIG Info | Cholesterol 25-hydroxylase (EC50 = 1.1 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 25 |
DFM Info
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Anhydrous lactose; Magnesium stearate; Sodium carbonate; Croscarmellose sodium; Polyoxyl 35 castor oil; Cellulose, microcrystalline
|
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyoxyl 35 castor oil | DIG Info | Cholesterol 25-hydroxylase (EC50 = 1.1 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Magnesium oxide; Croscarmellose sodium; Povidone k30; Microcrystalline cellulose
|
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| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; Citron Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Magnesium aluminum silicate; Talc; Croscarmellose sodium; Povidone k30; Microcrystalline cellulose
|
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| Dosage Form | Oral Tablet | |||||
| Company | St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Magnesium aluminum silicate; Talc; Croscarmellose sodium; Cellulose, microcrystalline; Povidone k29/32
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Magnesium aluminum silicate; Talc; Croscarmellose sodium; Microcrystalline cellulose; Povidone, unspecified
|
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| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Magnesium aluminum silicate; Talc; Croscarmellose sodium; Cellulose, microcrystalline; Povidones
|
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| Dosage Form | Oral Tablet | |||||
| Company | Actavis Pharma; NuCare Pharmaceuticals; Proficient Rx; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Magnesium aluminum silicate; Talc; Croscarmellose sodium; Cellulose, microcrystalline; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Magnesium aluminum silicate; Talc; Croscarmellose sodium; Cellulose, microcrystalline; Povidones
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| Dosage Form | Oral Tablet | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Pravastatin 10 mg tablet | Click to Show/Hide the Full List of Formulation(s): 20 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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D&c yellow no. 10; Magnesium stearate; Mannitol; Meglumine; Crospovidone; Hypromellose; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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D&c yellow no. 10; Magnesium stearate; Mannitol; Meglumine; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Blenheim Phamacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose; Sodium stearyl fumarate; Anhydrous dibasic calcium phosphate; Ferric oxide red; Croscarmellose sodium; Crospovidone; Povidone; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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D&c yellow no. 10; Magnesium stearate; Mannitol; Meglumine; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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D&c yellow no. 10; Magnesium stearate; Mannitol; Meglumine; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Glenmark Pharmaceutials; NuCare Pharmaceuticals; Preferred Pharamaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Meglumine; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol 8000
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Croscarmellose sodium; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Povidones; Sodium phosphate, dibasic
|
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| Dosage Form | Oral Tablet | |||||
| Company | AvPAK; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Anhydrous lactose; Sodium stearyl fumarate; Anhydrous dibasic calcium phosphate; Ferric oxide red; Croscarmellose sodium; Povidone k30; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | International Laboratories; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Anhydrous lactose; Sodium stearyl fumarate; Anhydrous dibasic calcium phosphate; Ferric oxide red; Croscarmellose sodium; Povidone k30; Crospovidone (15 mpa.s at 5%); Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Anhydrous lactose; Sodium stearyl fumarate; Ferric oxide red; Croscarmellose sodium; Crospovidone; Povidone k30; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Calcium stearate; Mannitol; Ferric oxide yellow; Crospovidone; Hydroxypropyl cellulose, low substituted
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cipla | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose monohydrate; Sodium stearyl fumarate; Ferric oxide red; Dihydroxyaluminum sodium carbonate
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Sodium bicarbonate; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Hypromellose 2910 (6 mpa.s); Polyethylene glycol 8000
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Magnesium oxide; Croscarmellose sodium; Povidone; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Accord Healthcare; NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Sodium carbonate; Croscarmellose sodium; Polyoxyl 35 castor oil; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; American Health Packaging; Bryant Ranch Prepack; Cadila Healthcare; Cardinal Health; NuCare Pharmaceuticals; State of Florida DOH Central Pharmacy; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyoxyl 35 castor oil | DIG Info | Cholesterol 25-hydroxylase (EC50 = 1.1 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Sodium carbonate; Croscarmellose sodium; Polyoxyl 35 castor oil; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyoxyl 35 castor oil | DIG Info | Cholesterol 25-hydroxylase (EC50 = 1.1 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Magnesium oxide; Croscarmellose sodium; Povidone k30; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; Citron Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Croscarmellose sodium; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Croscarmellose sodium; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Croscarmellose sodium; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex; Cardinal Health; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Pravastatin 20 mg tablet | Click to Show/Hide the Full List of Formulation(s): 34 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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D&c yellow no. 10; Magnesium stearate; Mannitol; Meglumine; Crospovidone; Hypromellose; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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D&c yellow no. 10; Magnesium stearate; Mannitol; Meglumine; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Blenheim Phamacal; Cardinal Health; NCS HealthCare of KY, Inc dba Vangard Labs; Rebel Distributors; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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D&c yellow no. 10; Magnesium stearate; Mannitol; Meglumine; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose; Sodium stearyl fumarate; Anhydrous dibasic calcium phosphate; Ferric oxide yellow; Croscarmellose sodium; Crospovidone; Povidone; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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D&c yellow no. 10; Magnesium stearate; Mannitol; Meglumine; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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D&c yellow no. 10; Magnesium stearate; Mannitol; Meglumine; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Clinical Solutions Wholesale; Glenmark Pharmaceutials; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Meglumine; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol 8000
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Croscarmellose sodium; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Povidones; Sodium phosphate, dibasic
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | AvPAK; NCS HealthCare of KY, Inc dba Vangard Labs; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose; Sodium stearyl fumarate; Ferric oxide yellow; Croscarmellose sodium; Crospovidone; Povidone; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Legacy Pharmaceutical; NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Anhydrous lactose; Sodium stearyl fumarate; Anhydrous dibasic calcium phosphate; Ferric oxide yellow; Croscarmellose sodium; Povidone k30; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%)
|
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Anhydrous lactose; Sodium stearyl fumarate; Anhydrous dibasic calcium phosphate; Ferric oxide yellow; Croscarmellose sodium; Povidone k30; Crospovidone (15 mpa.s at 5%); Microcrystalline cellulose
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Anhydrous lactose; Sodium stearyl fumarate; Ferric oxide yellow; Croscarmellose sodium; Crospovidone; Povidone k30; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline
|
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| Dosage Form | Oral Tablet | |||||
| Company | AvKARE; MedVantx; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose, unspecified form; Sodium stearyl fumarate; Anhydrous dibasic calcium phosphate; Ferric oxide yellow; Croscarmellose sodium; Crospovidone (15 mpa.s at 5%); Microcrystalline cellulose; Povidone, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose; Sodium stearyl fumarate; Ferric oxide red; Croscarmellose sodium; Crospovidone; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | International Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Anhydrous lactose; Sodium stearyl fumarate; Ferric oxide yellow; Croscarmellose sodium; Povidone k30; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%)
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | International Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Calcium stearate; Mannitol; Ferric oxide yellow; Crospovidone; Hydroxypropyl cellulose, low substituted
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cipla | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Sodium stearyl fumarate; Ferric oxide yellow; Dihydroxyaluminum sodium carbonate
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Sodium bicarbonate; Talc; Titanium dioxide; Crospovidone; Polyethylene glycol 6000; Silicon dioxide; Hypromellose 2910 (6 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Sodium bicarbonate; Talc; Titanium dioxide; Polyethylene glycol 6000; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (6 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Clinical Solutions Wholesale; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Magnesium oxide; Croscarmellose sodium; Povidone; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Accord Healthcare; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Sodium carbonate; Croscarmellose sodium; Polyoxyl 35 castor oil; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Aidarex Pharmaceuticals; American Health Packaging; Cadila Healthcare; Cardinal Health; PD-Rx Pharmaceuticals; Preferred Pharamaceuticals; Proficient Rx; St Marys Medical Park Pharmacy; State of Florida DOH Central Pharmacy; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyoxyl 35 castor oil | DIG Info | Cholesterol 25-hydroxylase (EC50 = 1.1 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 22 |
DFM Info
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Anhydrous lactose; Magnesium stearate; Sodium carbonate; Croscarmellose sodium; Polyoxyl 35 castor oil; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyoxyl 35 castor oil | DIG Info | Cholesterol 25-hydroxylase (EC50 = 1.1 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Sodium carbonate; Croscarmellose sodium; Polyoxyl 35 castor oil; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyoxyl 35 castor oil | DIG Info | Cholesterol 25-hydroxylase (EC50 = 1.1 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Magnesium aluminum silicate; Talc; Croscarmellose sodium; Povidone k30; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Magnesium aluminum silicate; Talc; Croscarmellose sodium; Cellulose, microcrystalline; Povidone k29/32
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Magnesium aluminum silicate; Talc; Croscarmellose sodium; Microcrystalline cellulose; Povidone, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Magnesium aluminum silicate; Talc; Croscarmellose sodium; Cellulose, microcrystalline; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Actavis Pharma; NuCare Pharmaceuticals; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Ferric oxide yellow; Magnesium oxide; Croscarmellose sodium; Cellulose, microcrystalline; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | E.R. Squibb & Sons | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Magnesium oxide; Croscarmellose sodium; Microcrystalline cellulose; Povidone, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Magnesium oxide; Croscarmellose sodium; Povidone k30; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; Citron Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Magnesium aluminum silicate; Talc; Croscarmellose sodium; Cellulose, microcrystalline; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Magnesium aluminum silicate; Talc; Croscarmellose sodium; Cellulose, microcrystalline; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Croscarmellose sodium; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Apotex; Clinical Solutions Wholesale; NuCare Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Croscarmellose sodium; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Pravastatin 80 mg tablet | Click to Show/Hide the Full List of Formulation(s): 21 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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D&c yellow no. 10; Magnesium stearate; Mannitol; Meglumine; Crospovidone; Hypromellose; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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D&c yellow no. 10; Magnesium stearate; Mannitol; Meglumine; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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D&c yellow no. 10; Magnesium stearate; Mannitol; Meglumine; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Glenmark Pharmaceutials; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Meglumine; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol 8000
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Meglumine; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Cellulose, microcrystalline; Hypromellose 2910 (15 mpa.s); Polyethylene glycol 8000
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Sodium phosphate, dibasic, unspecified form; Croscarmellose sodium; Silicon dioxide; Alcohol; Microcrystalline cellulose; Povidone, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Croscarmellose sodium; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Povidones; Sodium phosphate, dibasic
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Calcium stearate; Mannitol; Ferric oxide yellow; Crospovidone; Hydroxypropyl cellulose, low substituted
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cipla | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Sodium stearyl fumarate; Ferric oxide red; Ferric oxide yellow; Dihydroxyaluminum sodium carbonate
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Crospovidone; Povidone; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Sodium bicarbonate; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Hypromellose 2910 (6 mpa.s); Polyethylene glycol 8000
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Magnesium oxide; Croscarmellose sodium; Povidone; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Accord Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Sodium carbonate; Croscarmellose sodium; Polyoxyl 35 castor oil; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; Cadila Healthcare; RemedyRepack; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyoxyl 35 castor oil | DIG Info | Cholesterol 25-hydroxylase (EC50 = 1.1 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Sodium carbonate; Croscarmellose sodium; Polyoxyl 35 castor oil; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyoxyl 35 castor oil | DIG Info | Cholesterol 25-hydroxylase (EC50 = 1.1 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Sodium carbonate; Croscarmellose sodium; Polyoxyl 35 castor oil; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyoxyl 35 castor oil | DIG Info | Cholesterol 25-hydroxylase (EC50 = 1.1 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Magnesium oxide; Croscarmellose sodium; Povidone k30; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; Citron Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Magnesium aluminum silicate; Talc; Croscarmellose sodium; Cellulose, microcrystalline; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Actavis Pharma; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 18 |
DFM Info
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Lactose, unspecified form; Magnesium stearate; Ferric oxide yellow; Magnesium oxide; Croscarmellose sodium; Cellulose, microcrystalline; Povidones
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| Dosage Form | Oral Tablet | |||||
| Company | E.R. Squibb & Sons | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 19 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Croscarmellose sodium; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Drug Formulation 20 |
DFM Info
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Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Povidone k30; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%)
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 21 |
DFM Info
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Anhydrous lactose; Magnesium stearate; Crospovidone; Povidone k30; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Pravastatin Sodium 40mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Colloidal Silicon Dioxide; Crospovidone; Hydroxypropyl Methylcellulose; Magnesium Stearate; Mannitol; Meglumine; Microcrystalline Cellulose; Starch
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| Dosage Form | Tablet | |||||
| Company | Glenmark Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Pregelatinized starch | DIG Info | Multidrug resistance protein 1 (Protein expression downregulation) | [7] | |||
| Pravastatin Sodium 10mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Calcium Phosphate Dibasic Anhydrous; Croscarmellose Sodium; Crospovidone; Lactose Anhydrous; Microcrystalline Cellulose; Povidone; Sodium Stearyl Fumarate
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| Dosage Form | Tablet | |||||
| Company | Teva Pharmaceuticals Usa | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
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