Details of the Active Pharmaceutical Ingredient (API)

General Information of API (ID: D00742)
Name	Ziprasidone
Synonyms	Click to Show/Hide the Synonyms of This API Ziprasidone; 146939-27-7; Geodon; Zeldox; UNII-6UKA5VEJ6X; Ziprasidone free base; 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one; 6UKA5VEJ6X; CHEMBL708; CP-88059; CHEBI:10119; 146939-27-7 (free base); 5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one; 2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-; DSSTox_CID_3753; Ziprasidone [INN:BAN]; DSSTox_RID_77186; DSSTox_GSID_23753; ziprasidona; ziprasidonum; 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-2h-indol-2-one; 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one; Zipradon (TN); 2H-Indol-2-one, 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-; Ziprasidone (INN); CAS-146939-27-7; CP-88059-27; NCGC00186050-01; CP-880591; CP-8805927; HSDB 7745; GTPL59; C07568; 5-{2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one; SCHEMBL28028; MLS000759435; BIDD:GT0042; DTXSID4023753; HMS3742M19; ZINC538550; Tox21_112194; Tox21_113525; 4169AH; BDBM50048803; CZ0013; AKOS015900383; Tox21_112194_1; AM90310; CS-1071; DB00246; SDCCGSBI-0633778.P001; 5-{2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one; NCGC00263539-01; NCGC00263539-03; NCGC00263539-05; NCGC00263539-13; AC-23360; HY-14542; SMR000466328; FT-0654208; FT-0655916; VU0286234-2; 4770-EP2272537A2; 4770-EP2272841A1; 4770-EP2275420A1; 4770-EP2280010A2; 4770-EP2298731A1; 4770-EP2298776A1; 4770-EP2301936A1; 4770-EP2308875A1; 4770-EP2316836A1; D08687; W-5149; AB00639925-02; AB00639925-04; AB00639925_05; AB00639925_06; 883Z936; A808568; L000659; Q205517; CP 88059;CP-88059;CP88059; 5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one; 5-[2-[4-(1,2-benzothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydroindol-2-one; 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloranyl-1,3-dihydroindol-2-one; 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one; 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-2H-indole-2-one; 5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone); 5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole); 5-{2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-2,3-dihydro-1H-indol-2-one; Ziprasidone solution, 1.0 mg/mL in 1,2-dimethoxyethane, ampule of 1 mL, certified reference material
Clinical Status	Approved
Disease Indication	Schizophrenia		ICD-11: 6A20	[1]
PubChem CID	60854
Formula	C21H21ClN4OS
Canonical SMILES	C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54
InChI	1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)
InChIKey	MVWVFYHBGMAFLY-UHFFFAOYSA-N
	Click to Show/Hide the Molecular Data (Structure/Property) of This API
Structure	<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=60854"></iframe>
Structure	3D MOL		2D MOL
Physicochemical Properties	Molecular Weight	412.9	Topological Polar Surface Area	76.7
	XlogP	4	Complexity	573
	Heavy Atom Count	28	Rotatable Bond Count	4
	Hydrogen Bond Donor Count	1	Hydrogen Bond Acceptor Count	5

Full List of Drug Formulations (DFMs) Containing This API
Ziprasidone 40 mg capsule			Click to Show/Hide the Full List of Formulation(s): 19 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Phenoxyisopropanol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Povidone; Silicon dioxide; Alcohol; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Major Pharmaceuticals; RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Phenoxyisopropanol	DIG Info	Sodium channel alpha Nav1.4 (EC50 = 234422.88 nM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[6]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Crospovidone; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	Apotex; Proficient Rx; RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[5]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Crospovidone	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Propylene glycol 1,2-distearate; Ammonia n-13; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Fd&c red no. 3; Gelatin hydrolysate (porcine skin, mw 3000); Polysorbate 80; Povidone k30; Silicon dioxide; Alcohol, x-ray exposed (1000 rad); Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Gelatin	DIG Info	Mephenytoin 4-hydroxylase (EC50 = 20.5 uM)	[6]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Povidone k30; Silicon dioxide; Alcohol; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Dr Reddy's Laboratories; McKesson; RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Povidone k30; Silicon dioxide; Alcohol; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Phenoxyisopropanol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Silicon dioxide; Alcohol; Gelatin; Povidones; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Cardinal Health
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Phenoxyisopropanol	DIG Info	Sodium channel alpha Nav1.4 (EC50 = 234422.88 nM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 7	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Crospovidone (15 mpa.s at 5%); Gelatin; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	Clinical Solutions Wholesale
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[5]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 8	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Crospovidone (15 mpa.s at 5%); Gelatin, unspecified; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	American Health Packaging
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[5]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 9	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Crospovidone (15 mpa.s at 5%); Gelatin, unspecified; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	Golden State Medical Supply
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[5]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 10	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Magnesium stearate; Calcium silicate; Citric acid monohydrate; Propylene glycol; Sodium hydroxide; Titanium dioxide; Gelatin; Povidones; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	RemedyRepack; Sandoz
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[2]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[5]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 11	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	American Health Packaging; BluePoint Laboratories; Rebel Distributors
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[5]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 12	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, pregelatinized corn
Dosage Form	Oral Capsule
Company	Lupin Pharmaceuticals; RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[5]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 13	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 2; Ammonium chloride; Ferrosoferric oxide; Propylene glycol; Sucrose; Titanium dioxide; Gelatin; Polyethylene glycols; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	Macleods Pharmaceuticals; RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[2]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[5]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
Drug Formulation 14	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 2; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Ethylcellulose (10 mpa.s); Gelatin, unspecified; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Aurobindo Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[2]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 15	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin, unspecified; Polacrilin potassium; Povidone, unspecified; Shellac
Dosage Form	Oral Capsule
Company	Mylan Pharamceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 16	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Fd&c red no. 3; Cellulose, microcrystalline; Gelatin; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	Wockhardt
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 17	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate
Dosage Form	Oral Capsule
Company	RemedyRepack; State of Florida DOH Central Pharmacy
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 18	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose, unspecified form; Magnesium stearate
Dosage Form	Oral Capsule
Company	Avera McKennan Hospital; Greenstone
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 19	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose, unspecified form; Magnesium stearate; Starch, corn
Dosage Form	Oral Capsule
Company	Roerig
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Ziprasidone 60 mg capsule			Click to Show/Hide the Full List of Formulation(s): 20 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Phenoxyisopropanol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Povidone; Silicon dioxide; Alcohol; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Major Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Phenoxyisopropanol	DIG Info	Sodium channel alpha Nav1.4 (EC50 = 234422.88 nM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[6]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Propylene glycol 1,2-distearate; Ammonia n-13; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Fd&c red no. 3; Gelatin hydrolysate (porcine skin, mw 3000); Polysorbate 80; Povidone k30; Silicon dioxide; Alcohol, x-ray exposed (1000 rad); Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Gelatin	DIG Info	Mephenytoin 4-hydroxylase (EC50 = 20.5 uM)	[6]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Povidone k30; Silicon dioxide; Alcohol; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Dr Reddy's Laboratories; McKesson
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Phenoxyisopropanol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Silicon dioxide; Alcohol; Povidones; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Cardinal Health
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Phenoxyisopropanol	DIG Info	Sodium channel alpha Nav1.4 (EC50 = 234422.88 nM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Crospovidone; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	Apotex; Proficient Rx; RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Crospovidone	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Crospovidone (15 mpa.s at 5%); Gelatin; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	Clinical Solutions Wholesale
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 7	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Crospovidone (15 mpa.s at 5%); Gelatin, unspecified; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	American Health Packaging
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 8	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Crospovidone (15 mpa.s at 5%); Gelatin, unspecified; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	Bryant Ranch Prepack; Golden State Medical Supply
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 9	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Lactose monohydrate; Fd&c red no. 40; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Cellulose, microcrystalline; Gelatin; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	TYA Pharmaceuticals; Wockhardt
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[5]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[5]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 10	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Ammonia; Calcium silicate; Citric acid monohydrate; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Carboxymethylcellulose; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Sandoz
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 11	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Sodium lauryl sulfate; Ammonium chloride; Ferrosoferric oxide; Propylene glycol; Sucrose; Titanium dioxide; Gelatin; Polyethylene glycols; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	Macleods Pharmaceuticals; RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
Drug Formulation 12	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Ethylcellulose (10 mpa.s); Gelatin, unspecified; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Aurobindo Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 13	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Polacrilin potassium; Povidones; Shellac
Dosage Form	Oral Capsule
Company	Avera McKennan Hospital
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 14	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin, unspecified; Polacrilin potassium; Povidone, unspecified; Shellac
Dosage Form	Oral Capsule
Company	Mylan Pharamceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 15	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, pregelatinized corn
Dosage Form	Oral Capsule
Company	RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 16	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	American Health Packaging; BluePoint Laboratories; Cardinal Health; Rebel Distributors
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 17	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, pregelatinized corn
Dosage Form	Oral Capsule
Company	Lupin Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 18	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate
Dosage Form	Oral Capsule
Company	RemedyRepack; State of Florida DOH Central Pharmacy
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 19	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose, unspecified form; Magnesium stearate
Dosage Form	Oral Capsule
Company	Greenstone
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 20	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose, unspecified form; Magnesium stearate; Starch, corn
Dosage Form	Oral Capsule
Company	Roerig
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Ziprasidone 20 mg capsule			Click to Show/Hide the Full List of Formulation(s): 24 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Crospovidone; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	Apotex; Proficient Rx; RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[5]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Crospovidone	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Propylene glycol 1,2-distearate; Ammonia n-13; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Fd&c red no. 3; Gelatin hydrolysate (porcine skin, mw 3000); Polysorbate 80; Povidone k30; Silicon dioxide; Alcohol, x-ray exposed (1000 rad); Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Gelatin	DIG Info	Mephenytoin 4-hydroxylase (EC50 = 20.5 uM)	[6]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Povidone k30; Silicon dioxide; Alcohol; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Povidone k30; Silicon dioxide; Alcohol; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Dr Reddy's Laboratories; McKesson
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Crospovidone (15 mpa.s at 5%); Gelatin; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	Clinical Solutions Wholesale
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[5]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Crospovidone (15 mpa.s at 5%); Gelatin, unspecified; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	American Health Packaging
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[5]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 7	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Crospovidone (15 mpa.s at 5%); Gelatin, unspecified; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	A-S Medication Solutions; Golden State Medical Supply
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[5]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 8	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide red; Potassium hydroxide; Fd&c red no. 3; Polysorbate 80; Povidone; Silicon dioxide; 1-propoxy-2-propanol; Alcohol; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Major Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[6]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 9	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Povidone k30; Alcohol; Colloidal silicon dioxide; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 10	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide red; Potassium hydroxide; Fd&c red no. 3; Polysorbate 80; Silicon dioxide; 1-propoxy-2-propanol; Alcohol; Gelatin; Povidones; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Cardinal Health
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 11	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Magnesium stearate; Ammonia; Calcium silicate; Citric acid monohydrate; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Carboxymethylcellulose; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Proficient Rx; RemedyRepack; Sandoz; TYA Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[2]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[5]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 12	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	BluePoint Laboratories
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[5]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 13	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	American Health Packaging; Rebel Distributors
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[5]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 14	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, pregelatinized corn
Dosage Form	Oral Capsule
Company	Lupin Pharmaceuticals; RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[5]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 15	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin, unspecified; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Unit Dose Services
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[5]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 16	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 2; Ammonium chloride; Ferrosoferric oxide; Propylene glycol; Sucrose; Titanium dioxide; Gelatin; Polyethylene glycols; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	Macleods Pharmaceuticals; RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[2]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[5]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
Drug Formulation 17	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 2; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Ethylcellulose (10 mpa.s); Gelatin, unspecified; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Aurobindo Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[2]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 18	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin, unspecified; Polacrilin potassium; Povidone, unspecified; Shellac
Dosage Form	Oral Capsule
Company	Mylan Pharamceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 19	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Cellulose, microcrystalline; Gelatin; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	Wockhardt
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 20	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate
Dosage Form	Oral Capsule
Company	RemedyRepack; Stat Rx USA; State of Florida DOH Central Pharmacy
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 21	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose, unspecified form; Magnesium stearate
Dosage Form	Oral Capsule
Company	Greenstone
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 22	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose, unspecified form; Magnesium stearate; Starch, corn
Dosage Form	Oral Capsule
Company	Roerig; Unit Dose Services
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 23	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Starch, corn
Dosage Form	Oral Capsule
Company	RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 24	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Starch, corn
Dosage Form	Oral Capsule
Company	Lake Eire Medical & Surgical Supply DBA Quality Care Products
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Ziprasidone 80 mg capsule			Click to Show/Hide the Full List of Formulation(s): 21 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Crospovidone; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	Apotex; RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[5]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Crospovidone	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Propylene glycol 1,2-distearate; Ammonia n-13; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Fd&c red no. 3; Gelatin hydrolysate (porcine skin, mw 3000); Polysorbate 80; Povidone k30; Silicon dioxide; Alcohol, x-ray exposed (1000 rad); Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Gelatin	DIG Info	Mephenytoin 4-hydroxylase (EC50 = 20.5 uM)	[6]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Povidone k30; Silicon dioxide; Alcohol; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Dr Reddy's Laboratories; McKesson; NCS HealthCare of KY, Inc dba Vangard Labs; RemedyRepack; TYA Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Povidone k30; Silicon dioxide; Alcohol; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Phenoxyisopropanol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Povidone; Alcohol; Gelatin; Hydrated silica; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Major Pharmaceuticals; RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Phenoxyisopropanol	DIG Info	Sodium channel alpha Nav1.4 (EC50 = 234422.88 nM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[6]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Crospovidone (15 mpa.s at 5%); Gelatin; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	Clinical Solutions Wholesale
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[5]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 7	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Crospovidone (15 mpa.s at 5%); Gelatin, unspecified; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	American Health Packaging
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[5]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 8	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Crospovidone (15 mpa.s at 5%); Gelatin, unspecified; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	A-S Medication Solutions; Bryant Ranch Prepack; Golden State Medical Supply
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[5]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 9	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Phenoxyisopropanol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Alcohol; Gelatin; Hydrated silica; Povidones; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Cardinal Health
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Phenoxyisopropanol	DIG Info	Sodium channel alpha Nav1.4 (EC50 = 234422.88 nM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 10	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Magnesium stearate; Ammonia; Calcium silicate; Citric acid monohydrate; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Carboxymethylcellulose; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Sandoz; TYA Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[2]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[5]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 11	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Magnesium stearate; Ammonia; Calcium silicate; Citric acid monohydrate; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Carboxymethylcellulose; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[2]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[5]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 12	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	American Health Packaging; BluePoint Laboratories; Rebel Distributors
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[5]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 13	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, pregelatinized corn
Dosage Form	Oral Capsule
Company	Lupin Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[5]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 14	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 2; Ammonium chloride; Ferrosoferric oxide; Propylene glycol; Sucrose; Titanium dioxide; Gelatin; Polyethylene glycols; Shellac; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	Macleods Pharmaceuticals; RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[2]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[5]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
Drug Formulation 15	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 2; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Ethylcellulose (10 mpa.s); Gelatin, unspecified; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Aurobindo Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[2]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 16	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin, unspecified; Polacrilin potassium; Povidone, unspecified; Shellac
Dosage Form	Oral Capsule
Company	Mylan Pharamceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 17	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Polacrilin potassium; Povidones; Shellac
Dosage Form	Oral Capsule
Company	Avera McKennan Hospital
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 18	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Fd&c red no. 3; Cellulose, microcrystalline; Gelatin; Sodium starch glycolate type a potato
Dosage Form	Oral Capsule
Company	TYA Pharmaceuticals; Wockhardt
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[2]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 19	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate
Dosage Form	Oral Capsule
Company	RemedyRepack; State of Florida DOH Central Pharmacy
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 20	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose, unspecified form; Magnesium stearate
Dosage Form	Oral Capsule
Company	Greenstone
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]
Drug Formulation 21	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose, unspecified form; Magnesium stearate; Starch, corn
Dosage Form	Oral Capsule
Company	Roerig
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[7]

References
1	FDA label for approved ziprasidone from the official website of the U.S. Food and Drug Administration.
2	Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16009-16018.
3	2D- and 3D-QSAR of tocainide and mexiletine analogues acting as Na(v)1.4 channel blockers. Eur J Med Chem. 2009 Apr; 44(4):1477-85.
4	Synthesis and evaluation of dihydropyrroloquinolines that selectively antagonize P-glycoprotein. J Med Chem. 2004 Mar 11; 47(6):1413-22.
5	The activities of drug inactive ingredients on biological targets. Science. 2020 Jul 24;369(6502):403-413.
6	Mediation of in vitro cytochrome p450 activity by common pharmaceutical excipients. Mol Pharm. 2013 Jul 1;10(7):2739-48.
7	Effects of commonly used excipients on the expression of CYP3A4 in colon and liver cells. Pharm Res. 2010 Aug;27(8):1703-12.
8	Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration. Eur J Pharm Biopharm. 2008 Sep;70(1):279-88.

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