General Information of API (ID: D00439)
Name
Mirtazapine
Synonyms    Click to Show/Hide the Synonyms of This API
mirtazapine; 85650-52-8; Remeron; 61337-67-5; Mepirzepine; Remergil; Zispin; Remergon; Mirtazepine; 6-Azamianserin; Remeron SolTab; Mepirzapin; Mirtazipine; Promyrtil; Norset; ORG 3770; Mirtazapina; Avanza; Mirtazapinum; Mirtazapinum [INN-Latin]; Mirtazapina [INN-Spanish]; 2-Methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine; Org-3770; 2-methyl-1,2,3,4,10,14b-hexahydrobenzo[c]pyrazino[1,2-a]pyrido[3,2-f]azepine; 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine; CHEMBL654; 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine; Mirtazapine (Remeron, Avanza); CHEBI:6950; Mirtazapine, 98%; MFCD00865427; (R)-Org3770;(R)-6-Azamianserin; (S)-Org3770;(S)-6-Azamianserin; NCGC00025346-02; Pyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl-; Pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl-; Azamianserin; Mirtazapine [USAN:BAN:INN]; Smilon; 2-methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene; Org3770; SMR000466347; Remeron (TN); SR-01000597530; EINECS 288-060-6; Mepirzapine; 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c](2)benzazepine; Mirtazapine [USAN:USP:INN:BAN]; Mirtazapine solution; Reflex (TN); (1)-1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine; Mianserin, 6-Aza-; ME-2040; PubChem22104; 207516-99-2; DSSTox_CID_3325; DSSTox_RID_76979; DSSTox_GSID_23325; SCHEMBL35408; MLS000759460; MLS001076676; MLS001424294; MLS006011449; Mirtazapine (JAN/USP/INN); GTPL7241; PYR432; DTXSID0023325; Mirtazapine, >=98% (HPLC); HMS2052H03; HMS2233K03; HMS3268F21; HMS3370B05; HMS3374J01; HMS3394H03; HMS3413C11; HMS3657M13; HMS3677C11; HMS3713P13; HMS3884O18; BCP14560; BCP22244; HY-B0352; Mirtazapine 1.0 mg/ml in Methanol; Tox21_110965; ANW-42478; BBL009962; BDBM50115644; CM0152; PDSP1_001529; PDSP2_001513; STK711107; AKOS005530681; BCP9000930; CCG-101154; CCG-220556; DB00370; KS-1086; MCULE-1174883554; NC00404; NE42580; VA11306; NCGC00025346-01; NCGC00025346-08; AC-15480; AB0014270; CAS-61337-67-5; FT-0601544; FT-0628951; FT-0672414; SW197784-4; EN300-49851; C07570; D00563; J10458; AB00698265_08; 337M675; L001294; Q421930; SR-01000597530-1; SR-01000597530-4; BRD-A64977602-001-01-9; BRD-A64977602-001-04-3; Z2327131613; Mirtazapine, European Pharmacopoeia (EP) Reference Standard; Mirtazapine, United States Pharmacopeia (USP) Reference Standard; 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine.; 2-Methyl-1,2,3,4,10,14b-hexahydrobenzo-[c]pyrazino[1,2-a]pyrido[3,2-f]azepine
Clinical Status
Approved
Disease Indication Major depressive disorder ICD-11: 6A70 [1]
PubChem CID
4205
Formula
C17H19N3
Canonical SMILES
CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
InChI
1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3
InChIKey
RONZAEMNMFQXRA-UHFFFAOYSA-N
   Click to Show/Hide the Molecular Data (Structure/Property) of This API
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=4205"></iframe>
3D MOL 2D MOL
Physicochemical Properties Molecular Weight 265.35 Topological Polar Surface Area 19.4
XlogP 3.3 Complexity 345
Heavy Atom Count 20 Rotatable Bond Count 0
Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 3
Full List of Drug Formulations (DFMs) Containing This API
          Mirtazapine 15 mg tablet Click to Show/Hide the Full List of Formulation(s):        46 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Dimethyl benzyl carbinyl acetate; Ethyl butyrate; Maltodextrin; Sodium stearyl fumarate; Alpha.-tocopherol; Aspartame; Magnesium stearate; Mannitol; Caryophyllene; Xylitol; Acetaldehyde; Crospovidone; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Citrus sinensis fruit oil; Grapefruit oil; Orange oil
                   Dosage Form Disintegrating Oral Tablet
                   Company Watson Laboratories
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Caryophyllene DIG Info Cannabinoid CB2 receptor (Ki = 150 nM) [2]
Alpha-tocopherol DIG Info Glutathione S-transferase P (IC50 = 500 nM) [3]
Ethyl butyrate DIG Info Free fatty acid receptor 3 (EC50 = 10100 nM) [4]
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Dimethyl benzyl carbinyl acetate DIG Info PPAR-alpha (EC50 = 13000 nM) [6]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Sodium stearyl fumarate DIG Info Leukemia K562 cells (IC50 = 20.2 ug.mL-1) [8]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Dextrin DIG Info Colon cancer Caco-2 cells (Inhibition ratio > 55 %) [10]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous citric acid; Maltodextrin; Sodium stearyl fumarate; Alpha-tocopherol; Aspartame; Magnesium stearate; Mannitol; Crospovidone; Povidone k30; Silicon dioxide; Cellulose, microcrystalline
                   Dosage Form Disintegrating Oral Tablet
                   Company Cadila Healthcare; Zydus Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Alpha-tocopherol DIG Info Glutathione S-transferase P (IC50 = 500 nM) [3]
Kyselina citronova DIG Info Perilipin-1 (IC50 = 3708 nM) [11]
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Sodium stearyl fumarate DIG Info Leukemia K562 cells (IC50 = 20.2 ug.mL-1) [8]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Dextrin DIG Info Colon cancer Caco-2 cells (Inhibition ratio > 55 %) [10]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Hypromellose; Silicon dioxide; Cellulose, microcrystalline; Polydextrose; Polyethylene glycol; Starch, corn
                   Dosage Form Oral Tablet
                   Company Contract Pharmacal; State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [7]
Hypromellose DIG Info Cytochrome P450 3A5 (IC50 = 19.4 uM) [13]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 4 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
                   Dosage Form Oral Tablet
                   Company Mylan Pharamceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 5 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Ammonium laureth-5 sulfate; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Cardinal Health
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 6 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol; Starch, corn
                   Dosage Form Oral Tablet
                   Company Physicians Total Care
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 7 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
                   Dosage Form Oral Tablet
                   Company Aphena Pharma Solutions-Tennessee; Mylan Pharamceuticals; NCS HealthCare of KY, Inc dba Vangard Labs; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 8 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Starch, corn
                   Dosage Form Oral Tablet
                   Company McKesson
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 9 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Aspartame; Magnesium stearate; Mannitol; Xylitol; Crospovidone; Silicon dioxide; Cellulose, microcrystalline
                   Dosage Form Disintegrating Oral Tablet
                   Company Impax Generics
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Sodium stearyl fumarate DIG Info Leukemia K562 cells (IC50 = 20.2 ug.mL-1) [8]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 10 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Hypromellose 2910 (6 cps); Polydextrose; Polyethylene glycol; Starch, corn
                   Dosage Form Oral Tablet
                   Company State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 11 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Aspartame; Magnesium stearate; Mannitol; Xylitol; Silicon dioxide; Crospovidone, unspecified; Microcrystalline cellulose
                   Dosage Form Disintegrating Oral Tablet
                   Company Actavis Pharma
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Sodium stearyl fumarate DIG Info Leukemia K562 cells (IC50 = 20.2 ug.mL-1) [8]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 12 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Aspartame; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Xylitol; Silicon dioxide; Cassava; Crospovidone, unspecified; Dextrin palmitate (corn 20000 mw); Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Orange juice; Orange oil; Starch, corn
                   Dosage Form Disintegrating Oral Tablet
                   Company Teva Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 13 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Aspartame; Magnesium stearate; Mannitol; Crospovidone; Silicon dioxide; Cellulose, microcrystalline
                   Dosage Form Disintegrating Oral Tablet
                   Company Aurobindo Pharma; Citron Pharma; Greenstone
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 14 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Aspartame; Magnesium stearate; Mannitol; Citric acid monohydrate; Sodium bicarbonate; Sucrose; Crospovidone; Cellulose, microcrystalline; Hypromelloses; Povidones
                   Dosage Form Disintegrating Oral Tablet
                   Company Prasco
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 15 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Aspartame; Magnesium stearate; Mannitol; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Microcrystalline cellulose
                   Dosage Form Disintegrating Oral Tablet
                   Company Bryant Ranch Prepack; Cardinal Health
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 16 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Aspartame; Magnesium stearate; Mannitol; Citric acid monohydrate; Sodium bicarbonate; Sucrose; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Povidones
                   Dosage Form Disintegrating Oral Tablet
                   Company Organon Pharmaceuticals USA
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 17 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Hypromellose; Polyethylene glycol 400; Polyethylene glycol 6000; Povidone; Silicon dioxide; Starch, corn
                   Dosage Form Oral Tablet
                   Company McKesson
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Hypromellose DIG Info Cytochrome P450 3A5 (IC50 = 19.4 uM) [13]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [13]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
Polyethylene glycol 6000 DIG Info Albendazole monooxygenase (Inhibition ratio < 70 %) [14]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 18 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Povidone; Silicon dioxide; Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [13]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
Polyethylene glycol 6000 DIG Info Albendazole monooxygenase (Inhibition ratio < 70 %) [14]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 19 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Povidone k30; Silicon dioxide; Hypromellose 2910 (5 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
Polyethylene glycol 6000 DIG Info Albendazole monooxygenase (Inhibition ratio < 70 %) [14]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 20 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Povidone k30; Silicon dioxide; Hypromellose 2910 (5 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company PD-Rx Pharmaceuticals; RemedyRepack; Teva Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
Polyethylene glycol 6000 DIG Info Albendazole monooxygenase (Inhibition ratio < 70 %) [14]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 21 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Povidone k30; Silicon dioxide; Hypromellose 2910 (5 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Cardinal Health
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
Polyethylene glycol 6000 DIG Info Albendazole monooxygenase (Inhibition ratio < 70 %) [14]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 22 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Povidone; Colloidal silicon dioxide; Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company Kaiser Foundation Hospitals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [13]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
Polyethylene glycol 6000 DIG Info Albendazole monooxygenase (Inhibition ratio < 70 %) [14]
             Drug Formulation 23 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s)
                   Dosage Form Oral Tablet
                   Company Actavis Pharma; Clinical Solutions Wholesale; RemedyRepack; TYA Pharmaceuticals; Unit Dose Services
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 24 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose
                   Dosage Form Oral Tablet
                   Company Bryant Ranch Prepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 25 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Hypromellose; Silicon dioxide; Hydroxypropyl cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Hypromellose DIG Info Cytochrome P450 3A5 (IC50 = 19.4 uM) [13]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 26 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Polysorbate 80; Silicon dioxide; Hypromelloses; Polyethylene glycols; Starch, corn
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 27 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Polysorbate 80; Silicon dioxide; Hypromelloses; Polyethylene glycols; Starch, corn
                   Dosage Form Oral Tablet
                   Company Contract Pharmacal; Eon Labs
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 28 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Polyethylene glycol
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 29 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Polyethylene glycols
                   Dosage Form Oral Tablet
                   Company Rebel Distributors
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 30 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycol 8000
                   Dosage Form Oral Tablet
                   Company Clinical Solutions Wholesale; NuCare Pharmaceuticals; Preferred Pharamaceuticals; RemedyRepack; TYA Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
             Drug Formulation 31 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol 8000
                   Dosage Form Oral Tablet
                   Company Major Pharmaceuticals; Proficient Rx
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
             Drug Formulation 32 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company NorthStar Rx
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 33 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 34 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company NuCare Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 35 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Starch, corn
                   Dosage Form Oral Tablet
                   Company American Health Packaging
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 36 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose 2910 (6 mpa.s); Low-substituted hydroxypropyl cellulose, unspecified; Starch, corn
                   Dosage Form Oral Tablet
                   Company A-S Medication Solutions
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 37 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company A-S Medication Solutions; Aidarex Pharmaceuticals; Cardinal Health
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 38 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 39 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Aphena Pharma Solutions-Tennessee; Aurolife Pharma; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Medsource Pharmaceuticals; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 40 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Aurobindo Pharma
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 41 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Citron Pharma; Greenstone; Rebel Distributors; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 42 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polysorbate 80; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Polyethylene glycols
                   Dosage Form Oral Tablet
                   Company Stat Rx USA
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 43 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose, unspecified form; Magnesium stearate; Silicon dioxide; Hydroxypropyl cellulose (type h); Starch, corn
                   Dosage Form Oral Tablet
                   Company Organon Pharmaceuticals USA; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 44 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Magnesium stearate; Silicon dioxide; Hydroxypropyl cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Physicians Total Care
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 45 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company Sun Pharmaceutical Industries
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 46 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Colloidal silicon dioxide; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
          Mirtazapine 30 mg tablet Click to Show/Hide the Full List of Formulation(s):        42 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Dimethyl benzyl carbinyl acetate; Ethyl butyrate; Maltodextrin; Sodium stearyl fumarate; Alpha.-tocopherol; Aspartame; Magnesium stearate; Mannitol; Caryophyllene; Xylitol; Acetaldehyde; Crospovidone; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Citrus sinensis fruit oil; Grapefruit oil; Orange oil
                   Dosage Form Disintegrating Oral Tablet
                   Company Watson Laboratories
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Caryophyllene DIG Info Cannabinoid CB2 receptor (Ki = 150 nM) [2]
Alpha-tocopherol DIG Info Glutathione S-transferase P (IC50 = 500 nM) [3]
Ethyl butyrate DIG Info Free fatty acid receptor 3 (EC50 = 10100 nM) [4]
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Dimethyl benzyl carbinyl acetate DIG Info PPAR-alpha (EC50 = 13000 nM) [6]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Sodium stearyl fumarate DIG Info Leukemia K562 cells (IC50 = 20.2 ug.mL-1) [8]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Dextrin DIG Info Colon cancer Caco-2 cells (Inhibition ratio > 55 %) [10]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous citric acid; Maltodextrin; Sodium stearyl fumarate; Alpha-tocopherol; Aspartame; Magnesium stearate; Mannitol; Crospovidone; Povidone k30; Silicon dioxide; Cellulose, microcrystalline
                   Dosage Form Disintegrating Oral Tablet
                   Company Cadila Healthcare; Zydus Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Alpha-tocopherol DIG Info Glutathione S-transferase P (IC50 = 500 nM) [3]
Kyselina citronova DIG Info Perilipin-1 (IC50 = 3708 nM) [11]
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Sodium stearyl fumarate DIG Info Leukemia K562 cells (IC50 = 20.2 ug.mL-1) [8]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Dextrin DIG Info Colon cancer Caco-2 cells (Inhibition ratio > 55 %) [10]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Hypromellose; Silicon dioxide; Cellulose, microcrystalline; Polydextrose; Polyethylene glycol; Starch, corn
                   Dosage Form Oral Tablet
                   Company Contract Pharmacal
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [7]
Hypromellose DIG Info Cytochrome P450 3A5 (IC50 = 19.4 uM) [13]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 4 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
                   Dosage Form Oral Tablet
                   Company Mylan Pharamceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 5 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Ammonium laureth-5 sulfate; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Cardinal Health
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 6 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol; Starch, corn
                   Dosage Form Oral Tablet
                   Company Physicians Total Care; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 7 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
                   Dosage Form Oral Tablet
                   Company Aphena Pharma Solutions-Tennessee; Mylan Pharamceuticals; NCS HealthCare of KY, Inc dba Vangard Labs; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 8 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Starch, corn
                   Dosage Form Oral Tablet
                   Company McKesson
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 9 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Aspartame; Magnesium stearate; Mannitol; Xylitol; Crospovidone; Silicon dioxide; Cellulose, microcrystalline
                   Dosage Form Disintegrating Oral Tablet
                   Company Impax Generics
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Sodium stearyl fumarate DIG Info Leukemia K562 cells (IC50 = 20.2 ug.mL-1) [8]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 10 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Hydrated silica; Hypromellose 2208 (100 mpa.s); Polydextrose; Polyethylene glycol; Starch, corn
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
             Drug Formulation 11 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Aspartame; Magnesium stearate; Mannitol; Xylitol; Silicon dioxide; Crospovidone, unspecified; Microcrystalline cellulose
                   Dosage Form Disintegrating Oral Tablet
                   Company Actavis Pharma
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Sodium stearyl fumarate DIG Info Leukemia K562 cells (IC50 = 20.2 ug.mL-1) [8]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 12 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Aspartame; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Xylitol; Silicon dioxide; 20000 mw); Cassava; Crospovidone, unspecified; Dextrin palmitate (corn; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Orange juice; Orange oil; Starch, corn
                   Dosage Form Disintegrating Oral Tablet
                   Company Teva Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 13 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Aspartame; Magnesium stearate; Mannitol; Crospovidone; Silicon dioxide; Cellulose, microcrystalline
                   Dosage Form Disintegrating Oral Tablet
                   Company Aurobindo Pharma; Citron Pharma; Greenstone
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 14 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Aspartame; Magnesium stearate; Mannitol; Citric acid monohydrate; Sodium bicarbonate; Sucrose; Crospovidone; Cellulose, microcrystalline; Hypromelloses; Povidones
                   Dosage Form Disintegrating Oral Tablet
                   Company Prasco
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 15 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Ferric oxide red; Titanium dioxide; Polysorbate 80; Silicon dioxide; Hypromelloses; Polyethylene glycol
                   Dosage Form Oral Tablet
                   Company PD-Rx Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 16 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Ferric oxide red; Titanium dioxide; Polysorbate 80; Silicon dioxide; Hypromelloses; Polyethylene glycols; Starch, corn
                   Dosage Form Oral Tablet
                   Company Eon Labs
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 17 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Hypromellose 2910 (6 cps); Polydextrose; Polyethylene glycol; Starch, corn
                   Dosage Form Oral Tablet
                   Company State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 18 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Aspartame; Magnesium stearate; Mannitol; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Microcrystalline cellulose
                   Dosage Form Disintegrating Oral Tablet
                   Company Bryant Ranch Prepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 19 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Aspartame; Magnesium stearate; Mannitol; Citric acid monohydrate; Sodium bicarbonate; Sucrose; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Povidones
                   Dosage Form Disintegrating Oral Tablet
                   Company Organon Pharmaceuticals USA
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 20 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Hypromellose; Polyethylene glycol 400; Polyethylene glycol 6000; Povidone; Silicon dioxide; Starch, corn
                   Dosage Form Oral Tablet
                   Company McKesson
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Hypromellose DIG Info Cytochrome P450 3A5 (IC50 = 19.4 uM) [13]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [13]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
Polyethylene glycol 6000 DIG Info Albendazole monooxygenase (Inhibition ratio < 70 %) [14]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 21 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Povidone; Silicon dioxide; Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company Lake Eire Medical & Surgical Supply DBA Quality Care Products
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [13]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
Polyethylene glycol 6000 DIG Info Albendazole monooxygenase (Inhibition ratio < 70 %) [14]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 22 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Povidone k30; Silicon dioxide; Hypromellose 2910 (5 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Proficient Rx; Teva Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
Polyethylene glycol 6000 DIG Info Albendazole monooxygenase (Inhibition ratio < 70 %) [14]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 23 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Povidone k30; Silicon dioxide; Hypromellose 2910 (5 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Cardinal Health
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
Polyethylene glycol 6000 DIG Info Albendazole monooxygenase (Inhibition ratio < 70 %) [14]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 24 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Povidone; Colloidal silicon dioxide; Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company Kaiser Foundation Hospitals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [13]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
Polyethylene glycol 6000 DIG Info Albendazole monooxygenase (Inhibition ratio < 70 %) [14]
             Drug Formulation 25 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s)
                   Dosage Form Oral Tablet
                   Company A-S Medication Solutions; Actavis Pharma; Aidarex Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 26 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Polyethylene glycol
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 27 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Polyethylene glycols
                   Dosage Form Oral Tablet
                   Company Rebel Distributors
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 28 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Hypromellose; Silicon dioxide; Hydroxypropyl cellulose; Starch, corn; Starch, corn
                   Dosage Form Oral Tablet
                   Company State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Hypromellose DIG Info Cytochrome P450 3A5 (IC50 = 19.4 uM) [13]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 29 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company NuCare Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 30 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Starch, corn
                   Dosage Form Oral Tablet
                   Company American Health Packaging
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 31 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose 2910 (6 mpa.s); Low-substituted hydroxypropyl cellulose, unspecified; Starch, corn
                   Dosage Form Oral Tablet
                   Company A-S Medication Solutions; Bryant Ranch Prepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 32 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company A-S Medication Solutions; Cardinal Health; Proficient Rx; TYA Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 33 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company Cardinal Health
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 34 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 35 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Aphena Pharma Solutions-Tennessee; Aurolife Pharma; Contract Pharmacal; H. J. Harkins Company; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 36 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Aurobindo Pharma
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 37 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Citron Pharma; Greenstone; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Rebel Distributors; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 38 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycol 8000
                   Dosage Form Oral Tablet
                   Company Clinical Solutions Wholesale; DirectRX; NuCare Pharmaceuticals; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
             Drug Formulation 39 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company NorthStar Rx
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 40 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Polysorbate 80; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Polyethylene glycols
                   Dosage Form Oral Tablet
                   Company Stat Rx USA
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 41 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose, unspecified form; Magnesium stearate; Silicon dioxide; Hydroxypropyl cellulose (type h); Starch, corn
                   Dosage Form Oral Tablet
                   Company Organon Pharmaceuticals USA
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 42 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company Sun Pharmaceutical Industries
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
          Mirtazapine 45 mg tablet Click to Show/Hide the Full List of Formulation(s):        33 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous citric acid; Maltodextrin; Sodium stearyl fumarate; Alpha-tocopherol; Aspartame; Magnesium stearate; Mannitol; Crospovidone; Povidone k30; Silicon dioxide; Cellulose, microcrystalline
                   Dosage Form Disintegrating Oral Tablet
                   Company Cadila Healthcare; Zydus Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Alpha-tocopherol DIG Info Glutathione S-transferase P (IC50 = 500 nM) [3]
Kyselina citronova DIG Info Perilipin-1 (IC50 = 3708 nM) [11]
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Sodium stearyl fumarate DIG Info Leukemia K562 cells (IC50 = 20.2 ug.mL-1) [8]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Dextrin DIG Info Colon cancer Caco-2 cells (Inhibition ratio > 55 %) [10]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Hypromellose; Silicon dioxide; Cellulose, microcrystalline; Polydextrose; Polyethylene glycol; Starch, corn
                   Dosage Form Oral Tablet
                   Company Contract Pharmacal
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [7]
Hypromellose DIG Info Cytochrome P450 3A5 (IC50 = 19.4 uM) [13]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
                   Dosage Form Oral Tablet
                   Company Mylan Pharamceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 4 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol; Starch, corn
                   Dosage Form Oral Tablet
                   Company Physicians Total Care
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 5 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
                   Dosage Form Oral Tablet
                   Company Mylan Pharamceuticals; NCS HealthCare of KY, Inc dba Vangard Labs
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 6 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Aspartame; Magnesium stearate; Mannitol; Xylitol; Crospovidone; Silicon dioxide; Cellulose, microcrystalline
                   Dosage Form Disintegrating Oral Tablet
                   Company Impax Generics
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Sodium stearyl fumarate DIG Info Leukemia K562 cells (IC50 = 20.2 ug.mL-1) [8]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 7 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Aspartame; Magnesium stearate; Mannitol; Xylitol; Silicon dioxide; Crospovidone, unspecified; Microcrystalline cellulose
                   Dosage Form Disintegrating Oral Tablet
                   Company Actavis Pharma
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Sodium stearyl fumarate DIG Info Leukemia K562 cells (IC50 = 20.2 ug.mL-1) [8]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 8 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Aspartame; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Xylitol; Silicon dioxide; Cassava; Crospovidone, unspecified; Dextrin palmitate (corn 20000 mw); Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Orange juice; Orange oil; Starch, corn
                   Dosage Form Disintegrating Oral Tablet
                   Company Teva Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [12]
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 9 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Aspartame; Magnesium stearate; Mannitol; Crospovidone; Silicon dioxide; Cellulose, microcrystalline
                   Dosage Form Disintegrating Oral Tablet
                   Company Aurobindo Pharma; Bryant Ranch Prepack; Citron Pharma; Greenstone
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 10 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Aspartame; Magnesium stearate; Mannitol; Citric acid monohydrate; Sodium bicarbonate; Sucrose; Crospovidone; Cellulose, microcrystalline; Hypromelloses; Povidones
                   Dosage Form Disintegrating Oral Tablet
                   Company Physicians Total Care; Prasco
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 11 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Hypromellose 2910 (6 cps); Polydextrose; Polyethylene glycol; Starch, corn
                   Dosage Form Oral Tablet
                   Company State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [12]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 12 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Aspartame; Magnesium stearate; Mannitol; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Microcrystalline cellulose
                   Dosage Form Disintegrating Oral Tablet
                   Company Bryant Ranch Prepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 13 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Aspartame; Magnesium stearate; Mannitol; Citric acid monohydrate; Sodium bicarbonate; Sucrose; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Povidones
                   Dosage Form Disintegrating Oral Tablet
                   Company Organon Pharmaceuticals USA
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [5]
Aspartame DIG Info Pregnane X receptor (Ki = 13 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 14 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Povidone k30; Silicon dioxide; Hypromellose 2910 (5 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Teva Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
Polyethylene glycol 6000 DIG Info Albendazole monooxygenase (Inhibition ratio < 70 %) [14]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 15 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s)
                   Dosage Form Oral Tablet
                   Company Actavis Pharma; Rebel Distributors
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 16 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Povidone k30; Colloidal silicon dioxide; Hydroxypropyl methylcellulose e5 [ii]; Starch, corn
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
Polyethylene glycol 6000 DIG Info Albendazole monooxygenase (Inhibition ratio < 70 %) [14]
             Drug Formulation 17 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Povidone; Colloidal silicon dioxide; Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company Lake Eire Medical & Surgical Supply DBA Quality Care Products
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [13]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [14]
             Drug Formulation 18 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Hypromellose; Silicon dioxide; Hydroxypropyl cellulose; Starch, corn; Starch, corn
                   Dosage Form Oral Tablet
                   Company State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Hypromellose DIG Info Cytochrome P450 3A5 (IC50 = 19.4 uM) [13]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 19 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polysorbate 80; Silicon dioxide; Hypromelloses; Polyethylene glycols; Starch, corn
                   Dosage Form Oral Tablet
                   Company Eon Labs
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 20 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycol 8000
                   Dosage Form Oral Tablet
                   Company Clinical Solutions Wholesale; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
             Drug Formulation 21 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol 8000
                   Dosage Form Oral Tablet
                   Company Proficient Rx
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
             Drug Formulation 22 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycol 8000
                   Dosage Form Oral Tablet
                   Company DirectRX
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [9]
             Drug Formulation 23 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polysorbate 80; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Polyethylene glycols
                   Dosage Form Oral Tablet
                   Company Stat Rx USA
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 24 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Cardinal Health
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 25 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Aphena Pharma Solutions-Tennessee; Aurolife Pharma; Contract Pharmacal; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 26 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Citron Pharma; Greenstone; Rebel Distributors
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 27 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Aurobindo Pharma
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 28 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company NorthStar Rx
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 29 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Starch, corn
                   Dosage Form Oral Tablet
                   Company American Health Packaging
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 30 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose 2910 (6 mpa.s); Low-substituted hydroxypropyl cellulose, unspecified; Starch, corn
                   Dosage Form Oral Tablet
                   Company Bryant Ranch Prepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 31 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose, unspecified form; Magnesium stearate; Silicon dioxide; Hydroxypropyl cellulose (type h); Starch, corn
                   Dosage Form Oral Tablet
                   Company Organon Pharmaceuticals USA
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 32 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company Sun Pharmaceutical Industries
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 33 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Hydrated silica; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Modified corn starch (1-octenyl succinic anhydride)
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
          Mirtazapine 7.5 mg tablet Click to Show/Hide the Full List of Formulation(s):          8 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company NorthStar Rx
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company NCS HealthCare of KY, Inc dba Vangard Labs
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Cardinal Health
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 4 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Aurolife Pharma
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 5 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Citron Pharma; Greenstone
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 6 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (6 mpa.s); Starch, corn
                   Dosage Form Oral Tablet
                   Company Aurobindo Pharma
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 7 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (type l); Hydroxypropyl cellulose, low substituted; Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company NCS HealthCare of KY, Inc dba Vangard Labs
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
             Drug Formulation 8 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company Sun Pharmaceutical Industries
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [9]
References
1 FDA label for approved mirtazapine from the official website of the U.S. Food and Drug Administration.
2 Medicinal properties of terpenes found in Cannabis sativa and Humulus lupulus. Eur J Med Chem. 2018 Sep 5; 157:198-228.
3 Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example. J Med Chem. 2018 Sep 13; 61(17):7448-7470.
4 Design and Synthesis of 2-Alkylpyrimidine-4,6-diol and 6-Alkylpyridine-2,4-diol as Potent GPR84 Agonists. ACS Med Chem Lett. 2016 Mar 30; 7(6):579-83.
5 Pharmacological property optimization for allosteric ligands: A medicinal chemistry perspective. Bioorg Med Chem Lett. 2017 Jun 1; 27(11):2239-2258.
6 A stereo-controlled synthesis of 2,4-dimethyl-4-hydroxy-16-phenylhexadecanoic acid 1,4-lactone and its PPAR activities. Bioorg Med Chem Lett. 2010 Oct 15; 20(20):6017-9.
7 The activities of drug inactive ingredients on biological targets. Science. 2020 Jul 24;369(6502):403-413.
8 Synthesis and evaluation of (-)-Massoialactone and analogues as potential anticancer and anti-inflammatory agents. Eur J Med Chem. 2014 Apr 9; 76:291-300.
9 Effects of commonly used excipients on the expression of CYP3A4 in colon and liver cells. Pharm Res. 2010 Aug;27(8):1703-12.
10 Interactions between human multidrug resistance related protein (MRP2; ABCC2) and excipients commonly used in self-emulsifying drug delivery systems (SEDDS). Int J Pharm. 2013 Apr 15;447(1-2):192-8.
11 PubChem BioAssay data set.
12 Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16009-16018.
13 Mediation of in vitro cytochrome p450 activity by common pharmaceutical excipients. Mol Pharm. 2013 Jul 1;10(7):2739-48.
14 Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration. Eur J Pharm Biopharm. 2008 Sep;70(1):279-88.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.