Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00744) | |||||
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| Name |
Zolpidem
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| Synonyms |
Click to Show/Hide the Synonyms of This API
zolpidem; 82626-48-0; Ambien; Zolpidemum; N,N-Dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide; UNII-7K383OQI23; CHEMBL911; N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamide; CHEBI:10125; 7K383OQI23; Zolpidemum [Latin]; NCGC00095179-01; N,N,6-Trimethyl-2-p-tolylimidazo[1,2-a]pyridine-3-acetamide; SL-800750; N,N,6-Trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide; DSSTox_CID_25946; DSSTox_RID_81244; DSSTox_GSID_45946; 103188-50-7; Zolpidem [INN:BAN]; [3H]zolpidem; CAS-82626-48-0; SL-80.0750-23N; zolpidem Ambien; Zolpidem civ; Zolpidem (INN); Sanval (TN); SL800750; SL 800750; SL 80-0750; Imidazo(1,2-a)pyridine-3-acetamide, N,N,6-trimethyl-2-(4-methylphenyl)-; SCHEMBL80516; BSPBio_002278; BIDD:GT0785; SPECTRUM1505369; GTPL4348; GTPL4362; ZINC3876; DTXSID7045946; BDBM26266; AOB5703; HMS1922F22; BCP10205; Tox21_111471; MFCD00153885; STK627113; Zolpidem, >=98% (HPLC), solid; AKOS005560130; Tox21_111471_1; CCG-213403; CS-1468; DB00425; NCGC00095179-02; NCGC00095179-03; NCGC00095179-04; NCGC00095179-05; AS-35386; HY-17441; A-1776; C07219; D08690; AB00698471-07; AB00698471_09; 294Z936; Q218842; SR-01000763006; SR-01000763006-3; BRD-K44876623-001-01-1; SL 800750; SL-800750; SL800750; N,N,6-Trimethyl-2-(4-methylphenyl)-imidazo[1,2-a]pyridine-3-acetamide; 6-methyl-N,N-dimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide; N,N,6-Trimethyl-2-(4-Methyl Phenyl) Imidazo [1,2-alpha] Pyridine-3-Acetamide; N,N-Dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide #; N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide.; N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[3,2-a]pyridin-3-yl]acetamide; Zolpidem solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material
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| Clinical Status |
Approved
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| Disease Indication | Insomnia | ICD-11: 7A00 | [1] | ||
| PubChem CID | |||||
| Formula |
C19H21N3O
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| Canonical SMILES |
CC1=CC=C(C=C1)C2=C(N3C=C(C=CC3=N2)C)CC(=O)N(C)C
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| InChI |
1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3
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| InChIKey |
ZAFYATHCZYHLPB-UHFFFAOYSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=5732"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 307.4 | Topological Polar Surface Area | 37.6 | |
| XlogP | 2.5 | Complexity | 417 | ||
| Heavy Atom Count | 23 | Rotatable Bond Count | 3 | ||
| Hydrogen Bond Donor Count | 0 | Hydrogen Bond Acceptor Count | 2 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
|---|---|---|---|---|---|---|
| Zolpidem 10 mg tablet | Click to Show/Hide the Full List of Formulation(s): 29 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c red no. 30; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Titanium dioxide; Triacetin; Crospovidone; Povidone; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c red no. 30; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Titanium dioxide; Triacetin; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Povidone, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Cardinal Health; Mylan Pharamceuticals; PD-Rx Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c red no. 30; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Crospovidone; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Povidones
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Saccharin sodium anhydrous; Magnesium stearate; Mannitol; Crospovidone; Silicon dioxide; Starch, corn
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| Dosage Form | Sublingual Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Saccharin sodium anhydrous | DIG Info | Carbonic anhydrase I (Ki = 18540 nM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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Stearic acid; Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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Stearic acid; Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Aphena Pharma Solutions-Tennessee; Apotheca; Blenheim Phamacal; Bryant Ranch Prepack; DirectRX; Dispensing Solution; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Life Line Home Care Services; PD-Rx Pharmaceuticals; Proficient Rx; Qualitest Pharmaceuticals; RedPharm; Stat Rx USA; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Stearic acid; Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Blenheim Phamacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Polyethylene glycol 400; Povidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromellose 2910 (15 mpa.s); Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Kaiser Foundation Hospitals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose 2910 (15 mpa.s); Povidones; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Proficient Rx; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Carnauba wax; Hydroxypropyl cellulose (1200000 mw); Hypromellose 2910 (15 mpa.s); Microcrystalline cellulose; Povidone, unspecified; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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Lactose; Magnesium stearate; Talc; Titanium dioxide; Hypromellose; Silicon dioxide; Cellulose, microcrystalline; Polyethylene glycol; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Anhydrous lactose; Magnesium stearate; Titanium dioxide; Triacetin; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Lactose; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Cellulose, microcrystalline; Hydroxypropyl cellulose (type l); Hypromelloses
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| Dosage Form | Oral Tablet | |||||
| Company | Carlsbad Technology | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 14 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (5 mpa.s); Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Avera McKennan Hospital; Lake Eire Medical & Surgical Supply DBA Quality Care Products; NCS HealthCare of KY, Inc dba Vangard Labs; NuCare Pharmaceuticals; Proficient Rx; RemedyRepack; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 15 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (5 mpa.s); Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 16 |
DFM Info
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Anhydrous lactose; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Blenheim Phamacal; Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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Lactose; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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Anhydrous lactose; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Roxane Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s); Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; McKesson; NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 21 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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Lactose; Magnesium stearate; Titanium dioxide; Polysorbate 80; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Hypromelloses; Polyethylene glycol; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Titanium dioxide; Hypromellose; Cellulose, microcrystalline; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 1000; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyethylene glycol 1000 | DIG Info | Cytochrome P450 2E1 (IC50 = 75.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Titanium dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Sanofi-Aventis | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Magnesium stearate; Titanium dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromellose 2910 (5 mpa.s); Polyethylene glycol 8000; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Ferric oxide red
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Aphena Pharma Solutions-Tennessee; DirectRX; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Major Pharmaceuticals; Medsource Pharmaceuticals; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; Preferred Pharamaceuticals; Proficient Rx; RxChange; St Marys Medical Park Pharmacy; TYA Pharmaceuticals; Torrent Pharmaceuticals; Unit Dose Services | |||||
| Zolpidem 6.25 mg tablet | Click to Show/Hide the Full List of Formulation(s): 15 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Hydroxypropyl cellulose (type h); Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols
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|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [7] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Tartaric acid; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Polyvinyl alcohol; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycol
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Tartaric acid; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Polyvinyl alcohol; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Hypromelloses; Polyethylene glycols
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Tartaric acid; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Povidones
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Hypromelloses; Polyethylene glycols; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Avera McKennan Hospital; Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Tartaric acid; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Hypromellose 2208 (4000 mpa.s); Hypromellose 2910 (5 mpa.s); Methacrylic acid - methyl methacrylate copolymer (1:1); Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Povidone, unspecified
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Butyl alcohol; Magnesium stearate; Tartaric acid; Ammonia; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Talc; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Shellac; Sodium starch glycolate type a potato
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [7] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Potassium bitartrate; Ferric oxide red; Titanium dioxide; Hypromellose; Silicon dioxide; Cellulose, microcrystalline; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Potassium bitartrate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Sodium starch glycolate type a corn
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Winthrop | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Potassium bitartrate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Sanofi-Aventis | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Potassium bitartrate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Potassium bitartrate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Zolpidem 1.75 mg tablet | Click to Show/Hide the Full List of Formulation(s): 3 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sodium stearyl fumarate; Sucralose; Mannitol; Sorbitol; Ferric oxide yellow; Sodium bicarbonate; Sodium carbonate; Croscarmellose sodium; Crospovidone; Silicon dioxide
|
|||||
| Dosage Form | Sublingual Tablet | |||||
| Company | Purdue Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [8] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [10] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Aspartame; Magnesium stearate; Mannitol; Sodium bicarbonate; Sodium carbonate; Crospovidone; Povidone; Silicon dioxide; Polyvinyl acetate phthalate
|
|||||
| Dosage Form | Sublingual Tablet | |||||
| Company | Lupin Pharmaceuticals; Novel Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Crospovidone; Silicon dioxide; Peppermint; Saccharin sodium; Starch, corn
|
|||||
| Dosage Form | Sublingual Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Zolpidem 3.5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 3 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sodium stearyl fumarate; Sucralose; Mannitol; Sorbitol; Sodium bicarbonate; Sodium carbonate; Croscarmellose sodium; Crospovidone; Silicon dioxide
|
|||||
| Dosage Form | Sublingual Tablet | |||||
| Company | Purdue Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [8] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [10] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Aspartame; Magnesium stearate; Mannitol; Sodium bicarbonate; Sodium carbonate; Crospovidone; Povidone; Silicon dioxide; Polyvinyl acetate phthalate
|
|||||
| Dosage Form | Sublingual Tablet | |||||
| Company | Lupin Pharmaceuticals; Novel Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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Magnesium stearate; Mannitol; Crospovidone; Silicon dioxide; Peppermint; Saccharin sodium; Starch, corn
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| Dosage Form | Sublingual Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Zolpidem 5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 30 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c red no. 30; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Titanium dioxide; Triacetin; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Povidone, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c red no. 30; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Titanium dioxide; Triacetin; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polydextrose; Polyethylene glycols; Povidones
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| Dosage Form | Oral Tablet | |||||
| Company | Avera McKennan Hospital; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c red no. 30; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Crospovidone; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Povidones
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Cardinal Health; Kaiser Foundation Hospitals; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Anhydrous lactose; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferric oxide red; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Roxane Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 6 |
DFM Info
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Saccharin sodium anhydrous; Magnesium stearate; Mannitol; Crospovidone; Silicon dioxide; Starch, corn
|
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| Dosage Form | Sublingual Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Saccharin sodium anhydrous | DIG Info | Carbonic anhydrase I (Ki = 18540 nM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Aphena Pharma Solutions-Tennessee; Apotheca; Blenheim Phamacal; Bryant Ranch Prepack; DirectRX; Dispensing Solution; PD-Rx Pharmaceuticals; Proficient Rx; Qualitest Pharmaceuticals; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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Lactose; Fd&c red no. 40; Magnesium stearate; Titanium dioxide; Hypromellose; Polysorbate 80; Cellulose, microcrystalline; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Lactose, unspecified form; Fd&c red no. 40; Magnesium stearate; Titanium dioxide; Polysorbate 80; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | Sanofi-Aventis | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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Lactose; Fd&c red no. 40; Magnesium stearate; Titanium dioxide; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Povidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromellose 2910 (15 mpa.s); Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Kaiser Foundation Hospitals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Lactose; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Hypromellose; Silicon dioxide; Cellulose, microcrystalline; Polyethylene glycol; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose 2910 (15 mpa.s); Povidones; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Proficient Rx; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (5 mpa.s); Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Avera McKennan Hospital; NCS HealthCare of KY, Inc dba Vangard Labs; Preferred Pharamaceuticals; Proficient Rx; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 16 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Carnauba wax; Hydroxypropyl cellulose (1200000 mw); Hypromellose 2910 (15 mpa.s); Microcrystalline cellulose; Povidone, unspecified; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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Lactose; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Cellulose, microcrystalline; Hydroxypropyl cellulose (type l); Hypromelloses
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| Dosage Form | Oral Tablet | |||||
| Company | Carlsbad Technology | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Titanium dioxide; Polysorbate 80; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Hypromelloses; Polyethylene glycol; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromellose 2910 (15000 mpa.s); Hypromelloses; Sodium starch glycolate type b potato
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| Dosage Form | Oral Tablet | |||||
| Company | Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s); Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; NorthStar Rx; Preferred Pharamaceuticals; RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium tartrate; Ferric oxide red; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Cellulose, microcrystalline; Polyethylene glycols; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Sodium starch glycolate type a potato
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Titanium dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromellose 2910 (5 mpa.s); Polyethylene glycol 8000; Sodium starch glycolate type a potato
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Ferric oxide red
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Aphena Pharma Solutions-Tennessee; DirectRX; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Major Pharmaceuticals; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; Preferred Pharamaceuticals; Proficient Rx; RxChange; Torrent Pharmaceuticals; Unit Dose Services | |||||
| Zolpidem 12.5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 19 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Hydroxypropyl cellulose (type h); Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [7] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Tartaric acid; Ferric oxide yellow; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Potassium bitartrate; Ferric oxide yellow; Titanium dioxide; Hypromellose; Silicon dioxide; Cellulose, microcrystalline; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Tartaric acid; Ferric oxide yellow; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Hypromellose 2208 (4000 mpa.s); Hypromellose 2910 (5 mpa.s); Methacrylic acid - methyl methacrylate copolymer (1:1); Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Povidone, unspecified
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|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|
|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Tartaric acid; Ferric oxide yellow; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polydextrose; Polyethylene glycols; Povidones
|
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| Dosage Form | Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Tartaric acid; Ferric oxide yellow; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polydextrose; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Potassium bitartrate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Sodium starch glycolate type a corn
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | St Marys Medical Park Pharmacy; Winthrop | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Potassium bitartrate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; Proficient Rx; Sanofi-Aventis | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Potassium bitartrate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromellose, unspecified; Polyethylene glycol, unspecified; Sodium starch glycolate type a corn
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Potassium bitartrate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Aphena Pharma Solutions-Tennessee; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Potassium bitartrate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Potassium bitartrate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Butyl alcohol; Magnesium stearate; Tartaric acid; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Shellac; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [7] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Magnesium stearate; Sucrose; Titanium dioxide; Triacetin; Polyethylene glycol 1000; Silicon dioxide; Hypromelloses; Polydextrose
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyethylene glycol 1000 | DIG Info | Cytochrome P450 2E1 (IC50 = 75.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | DirectRX; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Proficient Rx; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Magnesium stearate; Sucrose; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose, unspecified; Polydextrose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Magnesium stearate; Sucrose; Titanium dioxide; Triacetin; Silicon dioxide; Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Avera McKennan Hospital; Golden State Medical Supply; Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
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