Details of the Active Pharmaceutical Ingredient (API)

General Information of API (ID: D00116)
Name	Cetirizine
Synonyms	Click to Show/Hide the Synonyms of This API cetirizine; 83881-51-0; Cetirizina; Cetirizin; Virlix; Cetirizinum; Zirtek; 2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid; CETIRIZINE HYDROCHLORIDE; 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid; Cetryn; Ziptek; CHEMBL1000; CHEBI:3561; AC-170; Cetirizinum [Latin]; (R)-Cetirizine (dihydrochloride); Hitrizin Film Tablet; Cetirizina [Spanish]; (2-(4-((4-Chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)acetic acid; (2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid; Zerviate; Zyrlex; Acetic acid, [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-; Cetirizine [INN:BAN]; Xarlin; 2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetic acid; Acetic acid, (2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-; 2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid; Cetiderm (TN); Levocetirizine (dihydrochloride); Cetirizine (INN); CetirizineHydrochloride; irizine; Benaday; Cetrizine Dihcl; [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid; HSDB 7739; Prestwick0_000503; Prestwick1_000503; Prestwick2_000503; Prestwick3_000503; SCHEMBL4176; TimTec1_002075; BSPBio_000425; BSPBio_002302; SPBio_002346; BPBio1_000469; GTPL1222; DTXSID4022787; BDBM22890; HMS1539O07; HMS3259D06; HMS3370I19; HMS3393N10; BCP08787; BCP28477; BBL009968; CC0153; Cet83881-51-0; STK711108; [(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethyl)oxy]acetic acid; 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid; AKOS003589059; AKOS021729457; AC-5545; CS-0886; DB00341; MCULE-8668839822; NC00696; SDCCGSBI-0206838.P002; NCGC00167781-01; NCGC00167781-02; NCGC00167781-03; NCGC00167781-04; NCGC00167781-07; NCGC00167781-12; NCGC00167781-18; HY-17042; ST024755; SBI-0206838.P001; AB0019096; DB-049948; FT-0603001; FT-0664488; EN300-52521; 81C510; C-5854; C07778; D07662; 24161-EP2272832A1; 24161-EP2281815A1; 24161-EP2295409A1; 24161-EP2301933A1; 24161-EP2305640A2; 24161-EP2311827A1; 24161-EP2314590A1; 110271-EP2284166A1; 110271-EP2298415A1; L000655; Q423075; J-005737; BRD-A42571354-300-05-4; BRD-A42571354-300-07-0; Z1182332250; [2-[4-[(4-Chlorophenyl)-phenyl methyl]-1-piperazinyl] ethoxy] acetic acid; [2-[4-[(4-chlorophenyl)phenylmethyl] 1-piperazinyl]-ethoxy] acetic acid; [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]-ethoxy]acetic acid; 2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazino}ethoxy)acetic acid; 2-(2-{4-[(4-chlorophenyl)phenylmethyl]piperazinyl}ethoxy)acetic acid
Clinical Status	Approved
Disease Indication	Allergy		ICD-11: 4A80	[1]
PubChem CID	2678
Formula	C21H25ClN2O3
Canonical SMILES	C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl
InChI	1S/C21H25ClN2O3/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26/h1-9,21H,10-16H2,(H,25,26)
InChIKey	ZKLPARSLTMPFCP-UHFFFAOYSA-N
	Click to Show/Hide the Molecular Data (Structure/Property) of This API
Structure	<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=2678"></iframe>
Structure	3D MOL		2D MOL
Physicochemical Properties	Molecular Weight	388.9	Topological Polar Surface Area	53
	XlogP	1.7	Complexity	443
	Heavy Atom Count	27	Rotatable Bond Count	8
	Hydrogen Bond Donor Count	1	Hydrogen Bond Acceptor Count	5

Full List of Drug Formulations (DFMs) Containing This API
Cetirizine 10 mg tablet			Click to Show/Hide the Full List of Formulation(s): 82 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Acesulfame potassium; Fumaric acid; Maltodextrin; Alpha.-tocopherol, dl-; Aspartame; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Talc; Croscarmellose sodium; Silicon dioxide; Betadex; Cellulose, microcrystalline; Ethylcelluloses; Hypromelloses
Dosage Form	Chewable Tablet
Company	Jubilant Cadista Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Acesulfame	DIG Info	Carbonic anhydrase IX (Ki = 2400 nM)	[2]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	Mannitol	DIG Info	Glycine receptor alpha-1 (EC50 = 12589.25 nM)	[4]
	Fumaric acid	DIG Info	HIF-prolyl hydroxylase 2 (IC50 = 19000 nM)	[5]
	Aspartame	DIG Info	Pregnane X receptor (Ki = 13 uM)	[6]
	DL-alpha-tocopherol	DIG Info	Presenilin 1 (EC50 > 100000 nM)	[7]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Dextrin	DIG Info	Colon cancer Caco-2 cells (Inhibition ratio > 55 %)	[9]
	Carmellose sodium	DIG Info	Albendazole monooxygenase (Protein expression upregulation)	[8]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Acesulfame potassium; Maltodextrin; Alpha.-tocopherol, dl-; Benzyl alcohol; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Silicon dioxide; Betadex; Microcrystalline cellulose
Dosage Form	Chewable Tablet
Company	CVS Pharmacy
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Benzyl alcohol	DIG Info	Indoleamine 2,3-dioxygenase 1 (IC50 = 1400 nM)	[10]
	Acesulfame	DIG Info	Carbonic anhydrase IX (Ki = 2400 nM)	[2]
	DL-alpha-tocopherol	DIG Info	Presenilin 1 (EC50 > 100000 nM)	[7]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[11]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Dextrin	DIG Info	Colon cancer Caco-2 cells (Inhibition ratio > 55 %)	[9]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Acesulfame potassium; Maltodextrin; Benzyl alcohol; Magnesium stearate; Alpha.-tocopherol acetate, dl-; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Silicon dioxide; Betadex; Cellulose, microcrystalline
Dosage Form	Chewable Tablet
Company	Sandoz
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Benzyl alcohol	DIG Info	Indoleamine 2,3-dioxygenase 1 (IC50 = 1400 nM)	[10]
	Acesulfame	DIG Info	Carbonic anhydrase IX (Ki = 2400 nM)	[2]
	Tocopheryl acetate	DIG Info	Prostate cancer LNCaP cells (EC50 = 38000 nM)	[12]
	Tocopheryl acetate	DIG Info	Breast cancer MCF7 cells (IC50 > 500000 nM)	[13]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[11]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Dextrin	DIG Info	Colon cancer Caco-2 cells (Inhibition ratio > 55 %)	[9]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Acesulfame potassium; Maltodextrin; Alpha.-tocopherol, dl-; Benzyl alcohol; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Silicon dioxide; Betadex; Cellulose, microcrystalline
Dosage Form	Chewable Tablet
Company	Major Pharmaceuticals; Rite Aid
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Benzyl alcohol	DIG Info	Indoleamine 2,3-dioxygenase 1 (IC50 = 1400 nM)	[10]
	Acesulfame	DIG Info	Carbonic anhydrase IX (Ki = 2400 nM)	[2]
	DL-alpha-tocopherol	DIG Info	Presenilin 1 (EC50 > 100000 nM)	[7]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[11]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Dextrin	DIG Info	Colon cancer Caco-2 cells (Inhibition ratio > 55 %)	[9]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Acesulfame potassium; Maltodextrin; Alpha.-tocopherol, dl-; Benzyl alcohol; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Silicon dioxide; Betadex; Microcrystalline cellulose
Dosage Form	Chewable Tablet
Company	Wal-Mart Stores
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Benzyl alcohol	DIG Info	Indoleamine 2,3-dioxygenase 1 (IC50 = 1400 nM)	[10]
	Acesulfame	DIG Info	Carbonic anhydrase IX (Ki = 2400 nM)	[2]
	DL-alpha-tocopherol	DIG Info	Presenilin 1 (EC50 > 100000 nM)	[7]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[11]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Dextrin	DIG Info	Colon cancer Caco-2 cells (Inhibition ratio > 55 %)	[9]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Acesulfame potassium; Maltodextrin; Benzyl alcohol; Magnesium stearate; Tocopheryl nicotinate, d-.alpha.; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Silicon dioxide; Betadex; Cellulose, microcrystalline
Dosage Form	Chewable Tablet
Company	L.N.K. International
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Benzyl alcohol	DIG Info	Indoleamine 2,3-dioxygenase 1 (IC50 = 1400 nM)	[10]
	Acesulfame	DIG Info	Carbonic anhydrase IX (Ki = 2400 nM)	[2]
	Tocopherol nicotinate	DIG Info	Nuclear factor-kappa B (EC50 = 189 nM)	[14]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[11]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Dextrin	DIG Info	Colon cancer Caco-2 cells (Inhibition ratio > 55 %)	[9]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 7	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Acesulfame potassium; Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Mannitol; Magnesium oxide; Sucrose; Talc; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Guar gum; Starch, corn
Dosage Form	Chewable Tablet
Company	Chain Drug Consortium; Sun Pharmaceutical Industries
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[6]
	Acesulfame	DIG Info	Carbonic anhydrase IX (Ki = 2400 nM)	[2]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[6]
	Mannitol	DIG Info	Glycine receptor alpha-1 (EC50 = 12589.25 nM)	[4]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Crospovidone	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 8	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Acesulfame potassium; D&c yellow no. 10; Fd&c red no. 40; Sucralose; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Polacrilin; Sodium starch glycolate type a potato
Dosage Form	Chewable Tablet
Company	Novel Laboratories
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[6]
	Sucralose	DIG Info	Carbonic anhydrase II (Ki = 300 nM)	[2]
	Acesulfame	DIG Info	Carbonic anhydrase IX (Ki = 2400 nM)	[2]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[6]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 9	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous citric acid; Sucralose; Magnesium stearate; Mannitol; Sodium bicarbonate; Hydroxypropyl cellulose (80000 mw); Silicon dioxide; Crospovidone (15 mpa.s at 5%); Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Microcrystalline cellulose; Sodium starch glycolate type a potato
Dosage Form	Disintegrating Oral Tablet
Company	Johnson & Johnson
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sucralose	DIG Info	Carbonic anhydrase II (Ki = 300 nM)	[2]
	Kyselina citronova	DIG Info	Perilipin-1 (IC50 = 3708 nM)	[14]
	Mannitol	DIG Info	Glycine receptor alpha-1 (EC50 = 12589.25 nM)	[4]
	Hydroxypropyl cellulose	DIG Info	Mephenytoin 4-hydroxylase (EC50 = 89.5 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 10	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Acesulfame potassium; Maltodextrin; Benzyl alcohol; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Betadex; Cellulose, microcrystalline
Dosage Form	Chewable Tablet
Company	Walgreens Company
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Benzyl alcohol	DIG Info	Indoleamine 2,3-dioxygenase 1 (IC50 = 1400 nM)	[10]
	Acesulfame	DIG Info	Carbonic anhydrase IX (Ki = 2400 nM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[11]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Dextrin	DIG Info	Colon cancer Caco-2 cells (Inhibition ratio > 55 %)	[9]
Drug Formulation 11	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
Dosage Form	Oral Tablet
Company	Mylan Pharamceuticals; St Marys Medical Park Pharmacy
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 12	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
Dosage Form	Oral Tablet
Company	Cardinal Health; Mylan Pharamceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 13	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol
Dosage Form	Oral Tablet
Company	Lake Eire Medical & Surgical Supply DBA Quality Care Products
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 14	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Triacetin; Povidone; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	Dolgencorp
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 15	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Triacetin; Povidone; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	International Laboratories
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 16	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Triacetin; Hypromelloses; Polydextrose; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Hy-Vee
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 17	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Triacetin; Hypromelloses; Polydextrose; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Aldi; American Sales Company; Army & Air Force Exchange Service; Costco Wholesale; Dolgencorp; H E B; Harmon Stores; Humana Pharmacy; Kroger Company; L. Perrigo Company; Lidl US; Meijer; Safeway; Sam's West; Shopko; Wakefern Food Corporation; Walgreens Company
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 18	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Triacetin; Hypromelloses; Polydextrose; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Avera McKennan Hospital; Big Lots Stores; Perrigo New York
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 19	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s)
Dosage Form	Oral Tablet
Company	Aurohealth; Fred's; McKesson
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Carmellose sodium	DIG Info	Albendazole monooxygenase (Protein expression upregulation)	[8]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[11]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 20	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Titanium dioxide; Hypromellose; Polysorbate 80; Povidone; Cellulose, microcrystalline; Polyethylene glycol; Starch, corn
Dosage Form	Oral Tablet
Company	Caraco Pharmaceutical Laboratories
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Hypromellose	DIG Info	Cytochrome P450 3A5 (IC50 = 19.4 uM)	[15]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[6]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 21	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Povidone; Polyethylene glycol; Starch, corn
Dosage Form	Oral Tablet
Company	Amneal Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Polyvinyl alcohol	DIG Info	Debrisoquine 4-hydroxylase (EC50 = 354.8 uM)	[15]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 22	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Povidones; Sodium starch glycolate type a corn; Starch, corn
Dosage Form	Oral Tablet
Company	Dolgencorp
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Polyvinyl alcohol	DIG Info	Debrisoquine 4-hydroxylase (EC50 = 354.8 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 23	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Hypromellose; Povidone; Polyethylene glycol; Starch, corn
Dosage Form	Oral Tablet
Company	Major Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Hypromellose	DIG Info	Cytochrome P450 3A5 (IC50 = 19.4 uM)	[15]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 24	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Titanium dioxide; Hypromellose; Povidone; Polyethylene glycol; Starch, corn
Dosage Form	Oral Tablet
Company	Unique Pharmaceutical Laboratories
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Hypromellose	DIG Info	Cytochrome P450 3A5 (IC50 = 19.4 uM)	[15]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 25	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Povidone; Hypromelloses; Starch, corn
Dosage Form	Oral Tablet
Company	CVS Pharmacy; Dr Reddy's Laboratories; McKesson
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[11]
Drug Formulation 26	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
Dosage Form	Oral Tablet
Company	Bryant Ranch Prepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Carmellose sodium	DIG Info	Albendazole monooxygenase (Protein expression upregulation)	[8]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 27	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
Dosage Form	Oral Tablet
Company	Johnson & Johnson
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Carmellose sodium	DIG Info	Albendazole monooxygenase (Protein expression upregulation)	[8]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 28	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Povidone k30; Colloidal silicon dioxide; Hypromellose 2910 (6 cps); Starch, corn
Dosage Form	Oral Tablet
Company	Torrent Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[11]
Drug Formulation 29	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Povidone k30; Colloidal silicon dioxide; Hypromellose 2910 (6 mpa.s); Starch, corn
Dosage Form	Oral Tablet
Company	Torrent Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[11]
Drug Formulation 30	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Povidone; Hypromelloses; Polydextrose; Polyethylene glycols
Dosage Form	Oral Tablet
Company	McKesson
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 31	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Povidone; Polyethylene glycol; Starch, corn
Dosage Form	Oral Tablet
Company	McKesson
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 32	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Povidone; Polyethylene glycols; Polyvinyl alcohol, unspecified; Starch, corn
Dosage Form	Oral Tablet
Company	Cardinal Health
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 33	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Povidone; Polyethylene glycols; Polyvinyl alcohol, unspecified; Starch, corn
Dosage Form	Oral Tablet
Company	Dolgencorp; P & L Development
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 34	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Greenbrier International; McKesson; Nash Finch Company; P & L Development
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Polyvinyl alcohol	DIG Info	Debrisoquine 4-hydroxylase (EC50 = 354.8 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 35	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Povidone; Polyethylene glycols; Polyvinyl alcohol, unspecified; Starch, corn
Dosage Form	Oral Tablet
Company	Rugby Laboratories
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 36	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Titanium dioxide; Triacetin; Povidone; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 37	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Povidone; Hypromelloses; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	AvKARE; AvPAK; Efficient Laboratories; Ohm Laboratories
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 38	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Povidone; Hypromelloses; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	Rebel Distributors
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 39	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Titanium dioxide; Triacetin; Povidone; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	Kmart Corporation; Publix Super Markets
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 40	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Povidone; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	H E B; Walgreens Company
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 41	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Povidone; Hypromelloses; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	Army & Air Force Exchange Service; CVS Pharmacy; Chain Drug Marketing Association; Family Dollar; Publix Super Markets; Select Brand; Shopko; Sunmark; Topco Associates; TriMarc Labs; Valu Merchandisers Company
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 42	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Povidone; Hypromelloses; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	Cardinal Health
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 43	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Povidone; Hypromelloses; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	Medline Industries
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 44	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Care One; Fred's; The Great Atlantic & Pacific Tea Company; Walgreens Company
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Polyvinyl alcohol	DIG Info	Debrisoquine 4-hydroxylase (EC50 = 354.8 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 45	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Hypromellose 2910 (5 mpa.s); Povidone k29/32; Starch, corn
Dosage Form	Oral Tablet
Company	Unichem Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[11]
Drug Formulation 46	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Titanium dioxide; Povidone; Hypromelloses; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	Life Line Home Care Services
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 47	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Titanium dioxide; Povidone; Hypromelloses; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 48	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 3350; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Starch, corn
Dosage Form	Oral Tablet
Company	American Health Packaging; Apotex; Cardinal Health; NuCare Pharmaceuticals; Rugby Laboratories
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Polyethylene glycol 3350	DIG Info	Albendazole monooxygenase (Protein expression upregulation)	[8]
Drug Formulation 49	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Povidone; Hypromelloses; Polyethylene glycol; Starch, corn
Dosage Form	Oral Tablet
Company	RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 50	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 3350; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Starch, corn
Dosage Form	Oral Tablet
Company	Major Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Polyethylene glycol 3350	DIG Info	Albendazole monooxygenase (Protein expression upregulation)	[8]
Drug Formulation 51	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Titanium dioxide; Povidone; Hypromelloses; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	DirectRX
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 52	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Titanium dioxide; Povidone; Hypromelloses; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 53	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Povidones; Sodium starch glycolate type a corn
Dosage Form	Oral Tablet
Company	Dolgencorp; Greenbrier International; P & L Development; The Great Atlantic & Pacific Tea Company
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 54	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Hypromellose 2910 (5 mpa.s); Povidone k29/32; Starch, corn
Dosage Form	Oral Tablet
Company	McKesson
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[11]
Drug Formulation 55	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Titanium dioxide; Povidone; Hypromelloses; Polyethylene glycol; Starch, corn
Dosage Form	Oral Tablet
Company	NuCare Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 56	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 1000; Hypromelloses; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Clinical Solutions Wholesale
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Polyethylene glycol 1000	DIG Info	Cytochrome P450 2E1 (IC50 = 75.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 57	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Titanium dioxide; Povidone; Hypromelloses; Polyethylene glycol; Starch, corn
Dosage Form	Oral Tablet
Company	Blenheim Phamacal; RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 58	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 3350; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Starch, corn
Dosage Form	Oral Tablet
Company	Rite Aid
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Polyethylene glycol 3350	DIG Info	Albendazole monooxygenase (Protein expression upregulation)	[8]
Drug Formulation 59	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Povidone; Hypromelloses; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	Rebel Distributors
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 60	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Titanium dioxide; Hypromellose; Cellulose, microcrystalline
Dosage Form	Oral Tablet
Company	Apotheca
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Hypromellose	DIG Info	Cytochrome P450 3A5 (IC50 = 19.4 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 61	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Povidone k30; Hypromelloses; Polyethylene glycol; Starch, corn
Dosage Form	Oral Tablet
Company	Ipca Laboratories
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 62	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Allegiant Health
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 63	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Hypromelloses; Polydextrose; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	SuperValu
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 64	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Hypromelloses; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	WinCo Foods
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 65	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Hypromelloses; Polydextrose; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	DZA Brands
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 66	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Hypromelloses; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Proficient Rx
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 67	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Titanium dioxide; Triacetin; Hypromelloses; Polydextrose; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	L Perrigo Company; Sam's West
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 68	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Hypromelloses; Polydextrose; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	7-Eleven; American Sales Company; Army & Air Force Exchange Service; BJWC; CVS Pharmacy; Cardinal Health; DZA Brands; Harmon Stores; Harris Teeter; Kinray; Kmart Corporation; Rite Aid; Save-A-Lot Food Stores; Target Corporation
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 69	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Hypromelloses; Polydextrose; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Amerisource Bergen; Wal-Mart Stores
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 70	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Hypromelloses; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Kinray
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 71	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Hypromelloses; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Chain Drug Consortium
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 72	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Hypromelloses; Polydextrose; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Target Corporation
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 73	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Hypromelloses; Polydextrose; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Topco Associates
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 74	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Titanium dioxide; Hypromelloses; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Aidarex Pharmaceuticals; Kaiser Foundation Hospitals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 75	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Hypromelloses; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Physicians Total Care; Preferred Pharamaceuticals; RemedyRepack; Sandoz
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 76	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose, unspecified form; Magnesium stearate; Titanium dioxide; Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified; Starch, corn
Dosage Form	Oral Tablet
Company	A-S Medication Solutions
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 77	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose, unspecified form; Magnesium stearate; Titanium dioxide; Hypromellose, unspecified; Povidone, unspecified; Starch, corn
Dosage Form	Oral Tablet
Company	Preferred Pharamaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 78	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	Walgreens Company
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 79	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Hypromelloses; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	NCS HealthCare of KY, Inc dba Vangard Labs
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 80	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Polyethylene glycols
Dosage Form	Oral Tablet
Company	Wal-Mart Stores
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 81	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Hypromelloses; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Taro Pharmaceuticals USA
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 82	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Povidone k29/32; Starch, corn
Dosage Form	Oral Tablet
Company	MedVantx; NorthStar Rx
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Cetirizine 5 mg tablet			Click to Show/Hide the Full List of Formulation(s): 18 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Acesulfame potassium; Fumaric acid; Maltodextrin; Alpha.-tocopherol, dl-; Aspartame; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Talc; Croscarmellose sodium; Silicon dioxide; Betadex; Cellulose, microcrystalline; Ethylcelluloses; Hypromelloses
Dosage Form	Chewable Tablet
Company	Jubilant Cadista Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Acesulfame	DIG Info	Carbonic anhydrase IX (Ki = 2400 nM)	[2]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	Mannitol	DIG Info	Glycine receptor alpha-1 (EC50 = 12589.25 nM)	[4]
	Fumaric acid	DIG Info	HIF-prolyl hydroxylase 2 (IC50 = 19000 nM)	[5]
	Aspartame	DIG Info	Pregnane X receptor (Ki = 13 uM)	[6]
	DL-alpha-tocopherol	DIG Info	Presenilin 1 (EC50 > 100000 nM)	[7]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Dextrin	DIG Info	Colon cancer Caco-2 cells (Inhibition ratio > 55 %)	[9]
	Carmellose sodium	DIG Info	Albendazole monooxygenase (Protein expression upregulation)	[8]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Acesulfame potassium; Maltodextrin; Benzyl alcohol; Magnesium stearate; Alpha.-tocopherol acetate, dl-; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Silicon dioxide; Betadex; Cellulose, microcrystalline
Dosage Form	Chewable Tablet
Company	Sandoz
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Benzyl alcohol	DIG Info	Indoleamine 2,3-dioxygenase 1 (IC50 = 1400 nM)	[10]
	Acesulfame	DIG Info	Carbonic anhydrase IX (Ki = 2400 nM)	[2]
	Tocopheryl acetate	DIG Info	Prostate cancer LNCaP cells (EC50 = 38000 nM)	[12]
	Tocopheryl acetate	DIG Info	Breast cancer MCF7 cells (IC50 > 500000 nM)	[13]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[11]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Dextrin	DIG Info	Colon cancer Caco-2 cells (Inhibition ratio > 55 %)	[9]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Acesulfame potassium; Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Mannitol; Magnesium oxide; Sucrose; Talc; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Guar gum; Starch, corn
Dosage Form	Chewable Tablet
Company	Sun Pharmaceutical Industries
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[6]
	Acesulfame	DIG Info	Carbonic anhydrase IX (Ki = 2400 nM)	[2]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[6]
	Mannitol	DIG Info	Glycine receptor alpha-1 (EC50 = 12589.25 nM)	[4]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Crospovidone	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Acesulfame potassium; D&c yellow no. 10; Fd&c red no. 40; Sucralose; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Polacrilin; Sodium starch glycolate type a potato
Dosage Form	Chewable Tablet
Company	Novel Laboratories
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[6]
	Sucralose	DIG Info	Carbonic anhydrase II (Ki = 300 nM)	[2]
	Acesulfame	DIG Info	Carbonic anhydrase IX (Ki = 2400 nM)	[2]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[6]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
Dosage Form	Oral Tablet
Company	Avera McKennan Hospital; Mylan Pharamceuticals; Physicians Total Care
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s)
Dosage Form	Oral Tablet
Company	Aurohealth
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Carmellose sodium	DIG Info	Albendazole monooxygenase (Protein expression upregulation)	[8]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[11]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 7	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Titanium dioxide; Hypromellose; Polysorbate 80; Povidone; Cellulose, microcrystalline; Polyethylene glycol; Starch, corn
Dosage Form	Oral Tablet
Company	Caraco Pharmaceutical Laboratories
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Hypromellose	DIG Info	Cytochrome P450 3A5 (IC50 = 19.4 uM)	[15]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[6]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 8	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Povidone; Polyethylene glycol; Starch, corn
Dosage Form	Oral Tablet
Company	Amneal Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Polyvinyl alcohol	DIG Info	Debrisoquine 4-hydroxylase (EC50 = 354.8 uM)	[15]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 9	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Titanium dioxide; Hypromellose; Povidone; Polyethylene glycol; Starch, corn
Dosage Form	Oral Tablet
Company	Pack Pharmaceuticals; Unique Pharmaceutical Laboratories
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Hypromellose	DIG Info	Cytochrome P450 3A5 (IC50 = 19.4 uM)	[15]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 10	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Povidone; Hypromelloses; Starch, corn
Dosage Form	Oral Tablet
Company	Wal-Mart Stores
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[11]
Drug Formulation 11	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Povidone k30; Colloidal silicon dioxide; Hypromellose 2910 (6 cps); Starch, corn
Dosage Form	Oral Tablet
Company	Torrent Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[11]
Drug Formulation 12	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Hypromellose 2910 (5 mpa.s); Povidone k29/32; Starch, corn
Dosage Form	Oral Tablet
Company	Unichem Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[11]
Drug Formulation 13	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Titanium dioxide; Povidone; Hypromelloses; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	Drug Ocean
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 14	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Titanium dioxide; Povidone; Hypromelloses; Polyethylene glycols; Starch, corn
Dosage Form	Oral Tablet
Company	RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 15	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 3350; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Starch, corn
Dosage Form	Oral Tablet
Company	Apotex
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
	Polyethylene glycol 3350	DIG Info	Albendazole monooxygenase (Protein expression upregulation)	[8]
Drug Formulation 16	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Povidone; Hypromelloses; Polyethylene glycol; Starch, corn
Dosage Form	Oral Tablet
Company	RemedyRepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[15]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 17	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose; Magnesium stearate; Titanium dioxide; Hypromelloses; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Bryant Ranch Prepack; Kaiser Foundation Hospitals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Drug Formulation 18	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Titanium dioxide; Hypromelloses; Polyethylene glycols; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	RemedyRepack; Sandoz
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[8]
Cetirizine 10 mg capsule			Click to Show/Hide the Full List of Formulation(s): 6 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Butylated hydroxytoluene; Butyl alcohol; Isopropyl alcohol; Mannitol; Sorbitol; Ammonia n-13; Glycerin; Propylene glycol; Sodium hydroxide; Titanium dioxide; Water; Polyethylene glycol 400; 1,4-sorbitan; Dimethicone; Gelatin; Shellac
Dosage Form	Oral Capsule
Company	Apotex
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Butylated hydroxytoluene	DIG Info	Carbonic anhydrase II (Ki = 630 nM)	[16]
	Mannitol	DIG Info	Glycine receptor alpha-1 (EC50 = 12589.25 nM)	[4]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[17]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[11]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[11]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Isopropyl alcohol; Sorbitol; Propylene glycol; Sodium hydroxide; Titanium dioxide; Water; Medium-chain triglycerides; Polyethylene glycol 400; Gelatin; Shellac; Sorbitan
Dosage Form	Oral Capsule
Company	Strides Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[17]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[11]
	Medium-chain triglyceride	DIG Info	Colon cancer Caco-2 cells (Inhibition ratio > 36 %)	[9]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[11]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Butylated hydroxytoluene; Mannitol; Sorbitol; Glycerin; Sodium hydroxide; Water; Polyethylene glycol 400; 1,4-sorbitan; Gelatin
Dosage Form	Oral Capsule
Company	Walgreens Company
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Butylated hydroxytoluene	DIG Info	Carbonic anhydrase II (Ki = 630 nM)	[16]
	Mannitol	DIG Info	Glycine receptor alpha-1 (EC50 = 12589.25 nM)	[4]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[11]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c yellow no. 6; Mannitol; Sorbitol; Glycerin; Sodium hydroxide; Water; Gelatin; Polyethylene glycols; Sorbitan
Dosage Form	Oral Capsule
Company	CVS Pharmacy; Chain Drug Consortium; Chain Drug Marketing Association; Fred's; KMART; Kroger; P & L Development; TopCare; Walgreens Company; Western Family Foods
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	Mannitol	DIG Info	Glycine receptor alpha-1 (EC50 = 12589.25 nM)	[4]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c yellow no. 6; Mannitol; Sorbitol; Glycerin; Sodium hydroxide; Water; Gelatin; Polyethylene glycols; Sorbitan
Dosage Form	Oral Capsule
Company	Cardinal Health; Care One; H E B; Harmon Stores; Hy-Vee; Publix Super Markets; Target Corporation; Walmart Stores
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	Mannitol	DIG Info	Glycine receptor alpha-1 (EC50 = 12589.25 nM)	[4]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Mannitol; Sorbitol; Glycerin; Sodium hydroxide; Water; Polyethylene glycol 400; Gelatin, unspecified; Sorbitan
Dosage Form	Oral Capsule
Company	Johnson & Johnson
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Mannitol	DIG Info	Glycine receptor alpha-1 (EC50 = 12589.25 nM)	[4]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[11]

References
1	FDA label for approved cetirizine from the official website of the U.S. Food and Drug Administration.
2	Sweet Binders: Carbonic Anhydrase IX in Complex with Sucralose. ACS Med Chem Lett. 2018 May 10; 9(7):657-661.
3	Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16009-16018.
4	Pharmacological property optimization for allosteric ligands: A medicinal chemistry perspective. Bioorg Med Chem Lett. 2017 Jun 1; 27(11):2239-2258.
5	Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases. J Med Chem. 2008 Nov 27; 51(22):7053-6.
6	The activities of drug inactive ingredients on biological targets. Science. 2020 Jul 24;369(6502):403-413.
7	Membrane anchoring -secretase modulators with terpene-derived moieties. Bioorg Med Chem Lett. 2013 Jul 1; 23(13):3852-6.
8	Effects of commonly used excipients on the expression of CYP3A4 in colon and liver cells. Pharm Res. 2010 Aug;27(8):1703-12.
9	Interactions between human multidrug resistance related protein (MRP2; ABCC2) and excipients commonly used in self-emulsifying drug delivery systems (SEDDS). Int J Pharm. 2013 Apr 15;447(1-2):192-8.
10	O-alkylhydroxylamines as rationally-designed mechanism-based inhibitors of indoleamine 2,3-dioxygenase-1. Eur J Med Chem. 2016 Jan 27; 108:564-576.
11	Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration. Eur J Pharm Biopharm. 2008 Sep;70(1):279-88.
12	First pharmacophore-based identification of androgen receptor down-regulating agents: discovery of potent anti-prostate cancer agents. Bioorg Med Chem. 2007 May 15; 15(10):3413-21.
13	Design and synthesis of analogs of vitamin E: antiproliferative activity against human breast adenocarcinoma cells. Bioorg Med Chem Lett. 1998 Sep 22; 8(18):2433-8.
14	PubChem BioAssay data set.
15	Mediation of in vitro cytochrome p450 activity by common pharmaceutical excipients. Mol Pharm. 2013 Jul 1;10(7):2739-48.
16	Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols. Bioorg Med Chem. 2009 Apr 15; 17(8):3207-11.
17	Synthesis and evaluation of dihydropyrroloquinolines that selectively antagonize P-glycoprotein. J Med Chem. 2004 Mar 11; 47(6):1413-22.

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