Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00349) | |||||
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| Name |
Lansoprazole
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| Synonyms |
Click to Show/Hide the Synonyms of This API
lansoprazole; 103577-45-3; Prevacid; Bamalite; Monolitum; Ogastro; Lansoprazol; Agopton; Limpidex; Lanzor; Opiren; Prevacid SoluTab; Lanzopral; Takepron; Lanproton; Lansopep; Lasoprol; Mesactol; Aprazol; Blason; Ketian; Lancid; Lanston; AG-1749; Lansoprazolum; Prevacid Iv; AG 1749; Lansox; A-65006; Prevacid 24HR; CHEBI:6375; Prezal; Pro Ulco; Compraz; Ilsatec; Prosogan; Suprecid; Zoprol; TAK-390MR; 2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl)methyl)sulfinyl)benzimidazole; MLS000069705; Lanzol-30; MFCD00866873; C16H14F3N3O2S; NCGC00015615-02; SMR000058469; Lansoprazol [INN-Spanish]; Lansoprazolum [INN-Latin]; CAS-103577-45-3; DSSTox_CID_3200; MLS-0003247.0001; Prevacid NapraPAC; DSSTox_RID_76922; DSSTox_GSID_23200; Prevacid I.V.; TAK 390MR; Lansophed; Lanzol; Lanzul; PrevOnco; 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]benzimidazole; Prevacid (TN); HSDB 7204; SR-01000000169; A 65006; BRN 4333393; Lanfast; Lapraz; ABT-006; Lansoprazole,(S); Lansoprazole [USAN:USP:INN:BAN]; CG-4801; PubChem16834; Spectrum_001580; CPD000058469; Prevacid Delayed Release; Opera_ID_1676; Prestwick0_001072; Prestwick1_001072; Prestwick2_001072; Prestwick3_001072; Spectrum2_000444; Spectrum3_000295; Spectrum4_000856; Spectrum5_001521; Lopac-L-8533; CHEMBL480; L 8533; cid_3883; Lopac0_000709; SCHEMBL22365; BSPBio_001084; BSPBio_001830; KBioGR_001491; KBioSS_002060; MLS000759405; MLS001074170; MLS001424235; BIDD:GT0006; DivK1c_000920; SPECTRUM1503926; SPBio_000488; SPBio_002992; BPBio1_001194; GTPL7208; DTXSID4023200; BDBM47032; HMS502N22; KBio1_000920; KBio2_002060; KBio2_004628; KBio2_007196; KBio3_001330; Lansoprazole (JP17/USP/INN); Levolansoprazole;(-)-Lansoprazole; NINDS_000920; HMS1571G06; HMS1922M04; HMS2052F05; HMS2093M07; HMS2098G06; HMS2234B10; HMS3262M19; HMS3264E12; HMS3269D15; HMS3371E21; HMS3394F05; HMS3413J05; HMS3654J17; HMS3677J05; HMS3715G06; Pharmakon1600-01503926; Pharmakon1600-01504282; ACT03358; BCP22331; BCP34129; EBD14854; Tox21_110184; Tox21_301023; Tox21_500709; BBL029072; BDBM50070208; CCG-39952; CL0035; NSC758638; NSC758710; STK621169; AKOS005554811; Tox21_110184_1; AC-1233; CS-1847; DB00448; KS-1075; Lansoprazole, >=98% (TLC), powder; LP00709; MCULE-8446262134; NC00411; NSC-758638; NSC-758710; SB19127; SDCCGSBI-0050687.P004; IDI1_000920; NCGC00015615-01; NCGC00015615-03; NCGC00015615-04; NCGC00015615-05; NCGC00015615-06; NCGC00015615-07; NCGC00015615-08; NCGC00015615-09; NCGC00015615-10; NCGC00015615-11; NCGC00015615-12; NCGC00015615-14; NCGC00015615-15; NCGC00023826-03; NCGC00023826-04; NCGC00023826-05; NCGC00023826-06; NCGC00023826-07; NCGC00254925-01; NCGC00261394-01; NCGC00381720-13; AK308448; HY-13662; SBI-0050687.P003; AB0005100; AB00052388; EU-0100709; FT-0610894; FT-0670721; FT-0670722; ST51015040; SW197226-4; D00355; AB00052388-17; AB00052388_18; AB00052388_19; 577L453; A800764; Q254296; J-007154; SR-01000000169-2; SR-01000000169-6; SR-01000000169-9; BRD-A49172652-001-05-7; BRD-A49172652-001-13-1; F2173-0222; Lansoprazole, British Pharmacopoeia (BP) Reference Standard; Lansoprazole, European Pharmacopoeia (EP) Reference Standard; Lansoprazole, United States Pharmacopeia (USP) Reference Standard; 2-({[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl}sulfinyl)benzimidazol e; 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]-methyl]sulfinyl]benzimidazole; 2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyrid-2-yl]methylsulfinyl]benzimidazole; 2-[3-methyl-4-(2,2,2-trifluoro-ethoxy)pyridin-2-ylmethanesulfinyl]-benzimidazole
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| Clinical Status |
Approved
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| Disease Indication | Duodenal ulcer | ICD-11: DA63 | [1] | ||
| PubChem CID | |||||
| Formula |
C16H14F3N3O2S
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| Canonical SMILES |
CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F
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| InChI |
1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)
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| InChIKey |
MJIHNNLFOKEZEW-UHFFFAOYSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=3883"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 369.4 | Topological Polar Surface Area | 87.1 | |
| XlogP | 2.8 | Complexity | 480 | ||
| Heavy Atom Count | 25 | Rotatable Bond Count | 5 | ||
| Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 8 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
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| Lansoprazole 15 mg tablet | Click to Show/Hide the Full List of Formulation(s): 3 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Maltitol; Sodium stearyl fumarate; Sucralose; Ascorbic acid; Cetyl alcohol; Mannitol; Meglumine; Sorbitol; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Copovidone k25-31; Crospovidone (15 mpa.s at 5%); Hypromelloses
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | CVS Pharmacy; Walgreens Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [4] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [6] | |||
| Maltitol | DIG Info | Carcinoma MDA-MB-231 cells (EC50 = 92350 nM) | [7] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Ascorbic acid | DIG Info | Albendazole monooxygenase (IC50 = 4.1 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 2 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Aspartame; Glyceryl monostearate; Magnesium stearate; Mannitol; Citric acid monohydrate; Ferric oxide red; Magnesium carbonate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Polysorbate 80; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Methacrylic acid; Polyethylene glycol
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [9] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [21] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 3 |
DFM Info
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Lactose monohydrate; Aspartame; Glyceryl monostearate; Magnesium stearate; Mannitol; Citric acid monohydrate; Ferric oxide red; Magnesium carbonate; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid; Microcrystalline cellulose; Polyethylene glycol, unspecified
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Takeda Pharmaceuticals America | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [9] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [21] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Lansoprazole 30 mg tablet | Click to Show/Hide the Full List of Formulation(s): 4 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Ethyl butyrate; Maltodextrin; Methyl cinnamate; Aspartame; Magnesium stearate; 3-hexenyl acetate, cis-; Ethyl isovalerate; Gamma.-decalactone; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Acacia; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Ethyl isovalerate | DIG Info | Wasabi receptor (EC50 = 8511.38 nM) | [11] | |||
| Cinnamaldehyde | DIG Info | Wasabi receptor (EC50 = 8511.38 nM) | [11] | |||
| Ethyl butyrate | DIG Info | Free fatty acid receptor 3 (EC50 = 10100 nM) | [12] | |||
| Cis-3-hexenyl acetate | DIG Info | Wasabi receptor (EC50 = 13300 nM) | [13] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [9] | |||
| Gamma-decalactone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 110000 nM) | [14] | |||
| Ethyl isovalerate | DIG Info | Gamma-aminobutyric acid receptor (IC50 = 2280 nM) | [15] | |||
| Cinnamaldehyde | DIG Info | Gamma-aminobutyric acid receptor (IC50 = 2280 nM) | [15] | |||
| Methyl cinnamate | DIG Info | Umbilical vein endothelial cells (IC50 = 100 ug.mL-1) | [16] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [17] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 2 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Aspartame; Glyceryl monostearate; Magnesium stearate; Mannitol; Citric acid monohydrate; Ferric oxide red; Magnesium carbonate; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Polysorbate 80; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Methacrylic acid; Polyethylene glycol
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [9] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [21] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 3 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Aspartame; Glyceryl monostearate; Magnesium stearate; Mannitol; Citric acid monohydrate; Ferric oxide red; Magnesium carbonate; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Methacrylic acid; Microcrystalline cellulose; Polyethylene glycol, unspecified
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [9] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [21] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 4 |
DFM Info
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|
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Aspartame; Glyceryl monostearate; Magnesium stearate; Mannitol; Citric acid monohydrate; Ferric oxide red; Magnesium carbonate; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid; Microcrystalline cellulose; Polyethylene glycol, unspecified
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Takeda Pharmaceuticals America | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [9] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [21] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Lansoprazole 15 mg capsule | Click to Show/Hide the Full List of Formulation(s): 40 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Polyethylene glycol 6000; Polysorbate 80; Alcohol; Fd&c green no. 3; Gelatin; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [8] | |||
| Drug Formulation 2 |
DFM Info
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Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Magnesium carbonate; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Polysorbate 80; Alcohol; Gelatin; Hydroxide ion; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Sodium starch glycolate type a corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Lannett Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [8] | |||
| Drug Formulation 3 |
DFM Info
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D&c red no. 28; D&c yellow no. 10; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Acetone; Ammonia; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Polyethylene glycol 4000; Polysorbate 80; Alcohol; Gelatin; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Chain Drug Consortium | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [9] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [8] | |||
| Drug Formulation 4 |
DFM Info
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D&c red no. 28; D&c yellow no. 10; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Acetone; Ammonia; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Polyethylene glycol 4000; Polysorbate 80; Alcohol; Gelatin, unspecified; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [9] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [8] | |||
| Drug Formulation 5 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Isopropyl alcohol; Acetone; Ammonia; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Polyethylene glycol 4000; Polysorbate 80; Fd&c green no. 3; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Breckenridge Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [8] | |||
| Drug Formulation 6 |
DFM Info
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Sodium lauryl sulfate; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Mannitol; Aluminum chlorohydrex propylene glycol; Ammonia; Ferrosoferric oxide; Magnesium carbonate; Talc; Titanium dioxide; Fd&c red no. 3; Polyethylene glycol 6000; Polysorbate 80; Alcohol; Gelatin; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Sodium starch glycolate type a corn; Sugarcane
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Lannett Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [9] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [8] | |||
| Drug Formulation 7 |
DFM Info
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D&c yellow no. 10; D&c red no. 33; Fd&c blue no. 1; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Polysorbate 80; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [18] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 8 |
DFM Info
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D&c yellow no. 10; D&c red no. 33; Fd&c blue no. 1; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Polysorbate 80; Silicon dioxide; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [18] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 9 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 1; Mannitol; Meglumine; Talc; Titanium dioxide; Polysorbate 80; Gelatin; Hypromelloses; Polyethylene glycols
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | American Sales Company; Amerisource Bergen; Army & Air Force Exchange Service; BJWC; Big Lots Stores; CVS Pharmacy; Cardinal Health; Costco Wholesale; DZA Brands; Dolgencorp; H E B; Harris Teeter; Hy-Vee; Kmart Corporation; Kroger Company; L. Perrigo Company; McKesson; Meijer; Perrigo New York; Publix Super Markets; Rite Aid; Rugby Laboratories; Safeway; Sam's West; Shopko; SuperValu; Target Corporation; Topco Associates; Wakefern Food Corporation; Wal-Mart Stores; Walgreens Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [9] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 10 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 1; Mannitol; Meglumine; Talc; Titanium dioxide; Polysorbate 80; Gelatin, unspecified; Hypromellose, unspecified; Polyethylene glycol, unspecified
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [9] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 11 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Polysorbate 80; Alcohol; Gelatin; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromelloses; Methacrylic acid; Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | A-S Medication Solutions; AvPAK; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 12 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Polysorbate 80; Alcohol; Gelatin; Hydroxypropyl cellulose (type e); Hydroxypropyl cellulose, low substituted; Hypromelloses; Methacrylic acid; Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 13 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Polysorbate 80; Alcohol; Gelatin; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromelloses; Methacrylic acid; Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 14 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Polysorbate 80; Alcohol; Gelatin; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromelloses; Methacrylic acid; Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 15 |
DFM Info
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Fd&c red no. 40; Fd&c blue no. 1; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Silicon dioxide; Gelatin; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Sam's West | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [9] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 16 |
DFM Info
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Sodium lauryl sulfate; Butyl alcohol; Fd&c blue no. 2; Isopropyl alcohol; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Magnesium carbonate; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polysorbate 20; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Xiromed | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [9] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [20] | |||
| Drug Formulation 17 |
DFM Info
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D&c yellow no. 10; Fd&c red no. 40; D&c red no. 33; Fd&c blue no. 1; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Chain Drug Consortium; Chain Drug Marketing Association; Fred's; Kroger; Major Pharmaceuticals; Nash Finch Company; P & L Development; Sam's West; Valu Merchandisers Company; Western Family Foods; Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [18] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 18 |
DFM Info
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D&c yellow no. 10; Fd&c red no. 40; D&c red no. 33; Fd&c blue no. 1; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Safeway | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [18] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 19 |
DFM Info
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Fd&c blue no. 2; Potassium chloride; Glyceryl 1-oleate; Ferric oxide yellow; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Carnauba wax; Carrageenan; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [9] | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [22] | |||
| Glyceryl monooleate | DIG Info | Diacylglycerol kinase alpha (Ki = 91000 nM) | [23] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 20 |
DFM Info
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Fd&c blue no. 2; Potassium chloride; Glyceryl 1-oleate; Ferric oxide yellow; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Carnauba wax; Carrageenan; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | A-S Medication Solutions; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [9] | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [22] | |||
| Glyceryl monooleate | DIG Info | Diacylglycerol kinase alpha (Ki = 91000 nM) | [23] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 21 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Fd&c green no. 3; Gelatin; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | GlaxoSmithKline; NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 22 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Fd&c green no. 3; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 23 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Fd&c green no. 3; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol; Starch, corn
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 24 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Fd&c green no. 3; Hydroxypropyl cellulose (type e); Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 25 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Fd&c green no. 3; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 26 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Fd&c green no. 3; Hydroxypropyl cellulose (1200000 mw); Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Takeda Pharmaceuticals America | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 27 |
DFM Info
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Sodium lauryl sulfate; Fd&c blue no. 2; Ammonia; Ferric oxide red; Ferric oxide yellow; Magnesium carbonate; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Gelatin; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Raw sugar; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | A-S Medication Solutions; BluePoint Laboratories; DirectRX; Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 28 |
DFM Info
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Sodium lauryl sulfate; Fd&c blue no. 2; Ammonia; Ferric oxide red; Ferric oxide yellow; Magnesium carbonate; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Gelatin, unspecified; Hydroxypropyl cellulose (1200000 mw); Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Raw sugar; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 29 |
DFM Info
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Fd&c red no. 40; Ammonia; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Fd&c green no. 3; Gelatin, unspecified; Hydroxypropyl cellulose (1200000 mw); Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 30 |
DFM Info
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Sodium lauryl sulfate; Fd&c blue no. 2; Ammonia; Ferric oxide red; Ferric oxide yellow; Magnesium carbonate; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Gelatin, unspecified; Hydroxypropyl cellulose (1200000 mw); Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Raw sugar; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 31 |
DFM Info
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Sodium lauryl sulfate; Fd&c blue no. 2; Ammonia; Ferric oxide red; Ferric oxide yellow; Magnesium carbonate; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Gelatin; Hydroxypropyl cellulose (type h); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Raw sugar; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 32 |
DFM Info
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Sodium lauryl sulfate; Fd&c blue no. 2; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Polysorbate 80; Gelatin; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Dr Reddy's Laboratories; Gericare Pharmaceuticals; Wal-Mart Stores; Walgreens Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [9] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [8] | |||
| Drug Formulation 33 |
DFM Info
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Fd&c red no. 40; Magnesium carbonate; Propylene glycol; Sodium hydroxide; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Fd&c green no. 3; Gelatin; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones; Shellac; Starch, corn
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|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 34 |
DFM Info
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Sodium lauryl sulfate; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sodium bicarbonate; Sucrose; Talc; Silicon dioxide; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Ajanta Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 35 |
DFM Info
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Sodium lauryl sulfate; Fd&c blue no. 2; Ammonia; Ferric oxide red; Ferric oxide yellow; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Gelatin; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Raw sugar; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [9] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 36 |
DFM Info
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Isopropyl alcohol; Acetone; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 4000; Polysorbate 80; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Actavis Inc | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [8] | |||
| Drug Formulation 37 |
DFM Info
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Fd&c blue no. 2; Ferric oxide yellow; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Gelatin; Hydroxypropyl cellulose; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Lifestar Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [9] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Drug Formulation 38 |
DFM Info
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Fd&c blue no. 1; Ferric oxide red; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Gelatin; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | AvKARE; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Drug Formulation 39 |
DFM Info
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Fd&c blue no. 1; Ferric oxide red; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Gelatin, unspecified; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Drug Formulation 40 |
DFM Info
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|||||
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Fd&c blue no. 1; Ferric oxide red; Ferrosoferric oxide; Magnesium carbonate; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Gelatin; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Lansoprazole 30 mg capsule | Click to Show/Hide the Full List of Formulation(s): 33 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Polyethylene glycol 6000; Polysorbate 80; Alcohol; Gelatin; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | A-S Medication Solutions; Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [8] | |||
| Drug Formulation 2 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Isopropyl alcohol; Acetone; Ammonia; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Polyethylene glycol 4000; Polysorbate 80; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Breckenridge Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [8] | |||
| Drug Formulation 3 |
DFM Info
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Sodium lauryl sulfate; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Mannitol; Aluminum chlorohydrex propylene glycol; Ammonia; Ferrosoferric oxide; Magnesium carbonate; Talc; Titanium dioxide; Fd&c red no. 3; Polyethylene glycol 6000; Polysorbate 80; Alcohol; Gelatin; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Sodium starch glycolate type a corn; Sugarcane
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Lannett Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [9] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [8] | |||
| Drug Formulation 4 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Polysorbate 80; Alcohol; Gelatin; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromelloses; Methacrylic acid; Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | AvPAK; NuCare Pharmaceuticals; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 5 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Polysorbate 80; Alcohol; Gelatin; Hydroxypropyl cellulose (type e); Hydroxypropyl cellulose, low substituted; Hypromelloses; Methacrylic acid; Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 6 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Water; Polysorbate 80; Alcohol; Gelatin; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromelloses; Methacrylic acid; Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 7 |
DFM Info
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Sodium lauryl sulfate; Butyl alcohol; Fd&c blue no. 2; Isopropyl alcohol; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Magnesium carbonate; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polysorbate 20; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Xiromed | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [9] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [20] | |||
| Drug Formulation 8 |
DFM Info
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D&c red no. 33; Fd&c blue no. 1; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Polysorbate 80; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 9 |
DFM Info
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D&c red no. 33; Fd&c blue no. 1; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 6000; Polysorbate 80; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 10 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Sucrose; Talc; Titanium dioxide; Water; Polysorbate 80; Alcohol; Gelatin, unspecified; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid; Polyethylene glycol, unspecified; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 11 |
DFM Info
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Fd&c blue no. 1; Ammonia; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Silicon dioxide; Gelatin, unspecified; Hydroxypropyl cellulose (1200000 mw); Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [9] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 12 |
DFM Info
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Fd&c blue no. 1; Ammonia; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Silicon dioxide; Gelatin; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [9] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 13 |
DFM Info
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Fd&c blue no. 1; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Silicon dioxide; Gelatin, unspecified; Hydroxypropyl cellulose (1200000 mw); Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [9] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 14 |
DFM Info
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Fd&c blue no. 2; Potassium chloride; Glyceryl 1-oleate; Ferric oxide red; Ferric oxide yellow; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Carnauba wax; Carrageenan; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Preferred Pharamaceuticals; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [9] | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [22] | |||
| Glyceryl monooleate | DIG Info | Diacylglycerol kinase alpha (Ki = 91000 nM) | [23] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 15 |
DFM Info
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Fd&c blue no. 1; Magnesium carbonate; Propylene glycol; Sodium hydroxide; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Polysorbate 80; Silicon dioxide; Gelatin; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [9] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 16 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Bryant Ranch Prepack; Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 17 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Bryant Ranch Prepack; PD-Rx Pharmaceuticals; RemedyRepack; Takeda Pharmaceuticals America | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 21 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [18] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [18] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 22 |
DFM Info
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Sodium lauryl sulfate; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sodium bicarbonate; Sucrose; Talc; Silicon dioxide; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Ajanta Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [10] | |||
| Drug Formulation 23 |
DFM Info
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Sodium lauryl sulfate; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Magnesium carbonate; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Gelatin; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Raw sugar; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | A-S Medication Solutions; Aidarex Pharmaceuticals; Dr Reddy's Laboratories; NuCare Pharmaceuticals; Preferred Pharamaceuticals; Proficient Rx; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 24 |
DFM Info
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Sodium lauryl sulfate; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Magnesium carbonate; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Gelatin, unspecified; Hydroxypropyl cellulose (1200000 mw); Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Raw sugar; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 25 |
DFM Info
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Sodium lauryl sulfate; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Magnesium carbonate; Propylene glycol; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Gelatin; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Raw sugar; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | BluePoint Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 26 |
DFM Info
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Isopropyl alcohol; Acetone; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 4000; Polysorbate 80; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Actavis Inc; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [8] | |||
| Drug Formulation 27 |
DFM Info
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Isopropyl alcohol; Acetone; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 4000; Polysorbate 80; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | A-S Medication Solutions; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Sterling Knight Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [8] | |||
| Drug Formulation 28 |
DFM Info
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Isopropyl alcohol; Acetone; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 4000; Polysorbate 80; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [8] | |||
| Drug Formulation 29 |
DFM Info
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Sodium lauryl sulfate; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polysorbate 80; Gelatin; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Raw sugar; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [18] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Drug Formulation 30 |
DFM Info
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Ferrosoferric oxide; Magnesium carbonate; Sucrose; Talc; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Gelatin; Hydroxypropyl cellulose; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Lifestar Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [9] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Drug Formulation 31 |
DFM Info
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Ferric oxide red; Ferrosoferric oxide; Magnesium carbonate; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Gelatin; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | AvKARE; Physicians Total Care; Proficient Rx; Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Drug Formulation 32 |
DFM Info
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Ferric oxide red; Ferrosoferric oxide; Magnesium carbonate; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Gelatin; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Drug Formulation 33 |
DFM Info
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Ferric oxide red; Ferrosoferric oxide; Magnesium carbonate; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Gelatin, unspecified; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
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