Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00348) | |||||
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| Name |
Lamotrigine
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| Synonyms |
Click to Show/Hide the Synonyms of This API
lamotrigine; 84057-84-1; 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine; Lamictal; Lamictal Cd; Lamictal XR; Lamotriginum [Latin]; Lamotrigina [Spanish]; Lamotriginum; BW 430C; BW-430C; Lamotrigina; Lamictal ODT; 3,5-Diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine; 1,2,4-Triazine-3,5-diamine, 6-(2,3-dichlorophenyl)-; 3,5-Diamino-6-(2,3-dichlorophenyl)-as-triazine; C9H7Cl2N5; LTG;BW430C; UNII-U3H27498KS; MFCD00865333; CHEMBL741; MLS000069685; CHEBI:6367; U3H27498KS; Lamotrigine, 98%; NCGC00015605-06; Labileno; Lamitor; SMR000058464; DSSTox_CID_3195; DSSTox_RID_76918; DSSTox_GSID_23195; Lamictal (TN); CAS-84057-84-1; BW430C; SR-01000000187; EINECS 281-901-8; HSDB 7526; EUR-1048; Lamotrigine [USAN:USP:INN:BAN]; Lamotrigine solution; Lamictal,Lamotrigine; zine-3,5-diamine; GI 267119X; Opera_ID_12; Tocris-1611; hydroxymethyl progesterone; Lopac-L-3791; L 3791; Lopac0_000688; SCHEMBL35439; MLS000759486; MLS001077325; MLS001423991; BIDD:GT0794; Lamotrigine (JAN/USP/INN); Lamotrigine, >=98%, powder; GTPL2622; TRI020; DTXSID2023195; ZINC13156; HMS2051C10; HMS2089M08; HMS2093P21; HMS2230L04; HMS3262I17; HMS3268G17; HMS3371O16; HMS3393C10; HMS3657A17; HMS3715H21; HMS3885M03; Pharmakon1600-01505610; BCP12156; HY-B0495; Lamotrigine 1.0 mg/ml in Methanol; Tox21_110179; Tox21_500688; ANW-44921; BDBM50031299; NSC746307; NSC759171; STK628377; AKOS005561147; Tox21_110179_1; 6-(2,2,4-triazine-3,5-diyldiamine; CCG-100856; DB00555; KS-1074; LP00688; MCULE-7648410888; NC00106; NE61394; NSC-746307; NSC-759171; SDCCGSBI-0050666.P003; SMP2_000303; NCGC00015605-01; NCGC00015605-02; NCGC00015605-03; NCGC00015605-04; NCGC00015605-05; NCGC00015605-07; NCGC00015605-08; NCGC00015605-09; NCGC00015605-10; NCGC00015605-23; NCGC00015605-24; NCGC00022936-02; NCGC00022936-04; NCGC00022936-05; NCGC00261373-01; AC-10298; AC-32483; AK-72807; AT-15488; BR-72807; Lamotrigine 100 microg/mL in Acetonitrile; SBI-0050666.P002; 6-(2,3-Dichloro-phenyl)-[1,2,4]tria; AB0014255; DB-014839; EU-0100688; FT-0602546; FT-0670713; FT-0670714; SW197486-3; 57L841; A11873; D00354; J10032; AB00384359-16; AB00384359_17; AB00384359_18; A840709; Q410346; 3,5-diamino-(2,3-dichlorophenyl)-1,2,4-triazine; Q-201221; SR-01000000187-2; SR-01000000187-4; SR-01000000187-7; BRD-K93460210-071-01-6; SR-01000000187-10; 3,5-diamino-6-(2,3,-dichlorophenyl)-1,2,4-triazine; 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine.; F2173-0540; Z1550648755; 6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamine; 6-[2,3-bis(chloranyl)phenyl]-1,2,4-triazine-3,5-diamine; Lamotrigine, British Pharmacopoeia (BP) Reference Standard; Lamotrigine, European Pharmacopoeia (EP) Reference Standard; 6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamine(lamotrigine); GI 267119X; 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine; Lamotrigine, United States Pharmacopeia (USP) Reference Standard; Lamotrigine, Pharmaceutical Secondary Standard; Certified Reference Material
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| Clinical Status |
Approved
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| Disease Indication | Bipolar disorder | ICD-11: 6A60 | [1] | ||
| PubChem CID | |||||
| Formula |
C9H7Cl2N5
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| Canonical SMILES |
C1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N
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| InChI |
1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16)
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| InChIKey |
PYZRQGJRPPTADH-UHFFFAOYSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=3878"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 256.089 | Topological Polar Surface Area | 90.7 | |
| XlogP | 1.4 | Complexity | 242 | ||
| Heavy Atom Count | 16 | Rotatable Bond Count | 1 | ||
| Hydrogen Bond Donor Count | 2 | Hydrogen Bond Acceptor Count | 5 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
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| Lamotrigine 100 mg tablet | Click to Show/Hide the Full List of Formulation(s): 40 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Sucralose; Aspartame; Magnesium stearate; Mannitol; Crospovidone; Povidone; Silicon dioxide; Dextrose; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Polyvinyl acetate; Starch, corn; Tricalcium phosphate
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; ScieGen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Stearic acid; Aspartame; Magnesium stearate; Mannitol; Sodium chloride; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Starch, corn
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Impax Generics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [4] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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Sodium stearyl fumarate; Sucralose; Magnesium stearate; Mannitol; Ferric oxide red; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Peppermint; Starch, corn
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:2)
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [4] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | TruPharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Aluminum oxide; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Wilshire Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Crospovidone; Povidone; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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Lactose monohydrate; Glyceryl monostearate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Polysorbate 80; Hypromelloses; Methacrylic acid
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Drug Formulation 9 |
DFM Info
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Fd&c yellow no. 6; Magnesium stearate; Mannitol; Croscarmellose sodium; Povidone k30; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Povidone; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Crospovidone; Cellulose, microcrystalline; Povidones
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| Dosage Form | Oral Tablet | |||||
| Company | Clinical Solutions Wholesale; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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Fd&c yellow no. 6; Magnesium stearate; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Povidone k25
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| Dosage Form | Oral Tablet | |||||
| Company | Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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Lactose monohydrate; Diethyl phthalate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Polyethylene glycol 400; Hypromellose 2910 (6 mpa.s); Hypromellose phthalate (31% phthalate, 40 cst)
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Drug Formulation 16 |
DFM Info
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | McKesson; NCS HealthCare of KY, Inc dba Vangard Labs; Physicians Total Care; RemedyRepack; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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Lactose; Fd&c yellow no. 6; Magnesium stearate; Povidone; Cellulose, microcrystalline; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Physicians Total Care; Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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Lactose; Fd&c yellow no. 6; Magnesium stearate; Povidone; Cellulose, microcrystalline; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Hikma Pharmaceutical; West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Povidones; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Diethyl phthalate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Ascend Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Povidone k30; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose; Fd&c yellow no. 6; Magnesium stearate; Cellulose, microcrystalline; Povidones; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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Lactose, unspecified form; Fd&c yellow no. 6; Magnesium stearate; Cellulose, microcrystalline; Povidones; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Sucralose; Mannitol; Crospovidone (15 mpa.s at 5%); Ethylcellulose (100 mpa.s)
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; NorthStar Rx; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Povidone k30; Silicon dioxide; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Proficient Rx; RemedyRepack; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Povidone k30; Silicon dioxide; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | H. J. Harkins Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Povidone; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Alembic Pharmaceuticals; McKesson; NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 31 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Povidone; Cellulose, microcrystalline; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare; NCS HealthCare of KY, Inc dba Vangard Labs; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Povidone k30; Colloidal silicon dioxide; Sodium starch glycolate type a potato
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cipla | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Povidone k30; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydroxypropyl cellulose, low substituted; Sodium starch glycolate type a potato
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Povidone k29/32; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; DirectRX; TYA Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 35 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Povidone k29/32; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack; Unichem Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 36 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Povidones; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Microcrystalline cellulose; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 38 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 39 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Povidones; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 40 |
DFM Info
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|||||
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Ferric oxide red; Ferric oxide yellow; Hypromelloses; Methacrylic acid
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| Lamotrigine 200 mg tablet | Click to Show/Hide the Full List of Formulation(s): 40 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sucralose; Aspartame; Magnesium stearate; Mannitol; Crospovidone; Povidone; Silicon dioxide; Dextrose; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Polyvinyl acetate; Starch, corn; Tricalcium phosphate
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; ScieGen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Stearic acid; Aspartame; Magnesium stearate; Mannitol; Sodium chloride; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Starch, corn
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Impax Generics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [4] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [11] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [11] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Sodium stearyl fumarate; Sucralose; Magnesium stearate; Mannitol; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Peppermint; Starch, corn
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Glyceryl monostearate; Magnesium stearate; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Polysorbate 80; Hypromelloses; Methacrylic acid
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Croscarmellose sodium; Crospovidone; Povidone; Aluminum oxide; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Mannitol; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | TruPharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [11] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Mannitol; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Aluminum oxide; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Wilshire Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [11] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Diethyl phthalate; Indigotindisulfonate sodium; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Hypromellose 2910 (6 mpa.s); Hypromellose phthalate (31% phthalate, 40 cst)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Drug Formulation 10 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Indigotindisulfonate sodium; Magnesium stearate; Povidone k30; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Fd&c blue no. 1; Magnesium stearate; Mannitol; Croscarmellose sodium; Povidone k30; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [11] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Croscarmellose sodium; Crospovidone; Aluminum oxide; Cellulose, microcrystalline; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Taro Pharmaceuticals USA; Upsher-Smith Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Povidone; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Fd&c blue no. 2; Magnesium stearate; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Povidone k25
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Povidone k30; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Povidone k30; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Ascend Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [11] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Povidone; Cellulose, microcrystalline; Colloidal silicon dioxide; Sodium starch glycolate type a potato; Starch, corn
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose; Fd&c blue no. 2; Magnesium stearate; Povidone; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose; Fd&c blue no. 2; Magnesium stearate; Povidone; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Hikma Pharmaceutical; West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose monohydrate; Diethyl phthalate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Povidone k30; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Cellulose, microcrystalline; Povidone k29/32; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack; Unichem Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Fd&c blue no. 2; Magnesium stearate; Povidone k30; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydroxypropyl cellulose, low substituted; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Cellulose, microcrystalline; Povidone k29/32; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Lactose, unspecified form; Fd&c blue no. 2; Magnesium stearate; Cellulose, microcrystalline; Povidones; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Sucralose; Mannitol; Crospovidone (15 mpa.s at 5%); Ethylcellulose (100 mpa.s)
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Silicon dioxide; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:2)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Povidone k30; Silicon dioxide; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Povidone; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Alembic Pharmaceuticals; McKesson; NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Povidone; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 35 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Povidone; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 36 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Povidone k30; Colloidal silicon dioxide; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cipla | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Povidones; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 38 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Microcrystalline cellulose; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 39 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 40 |
DFM Info
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|||||
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Silicon dioxide; Hypromelloses; Methacrylic acid
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Lamotrigine 25 mg tablet | Click to Show/Hide the Full List of Formulation(s): 53 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sucralose; Aspartame; Magnesium stearate; Mannitol; Crospovidone; Povidone; Silicon dioxide; Dextrose; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Polyvinyl acetate; Starch, corn; Tricalcium phosphate
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; ScieGen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Stearic acid; Aspartame; Magnesium stearate; Mannitol; Sodium chloride; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Starch, corn
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Impax Generics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [4] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Sodium stearyl fumarate; Sucralose; Magnesium stearate; Mannitol; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Peppermint; Starch, corn
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Glyceryl monostearate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Hypromelloses; Methacrylic acid
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Aspartame; Magnesium stearate; Mannitol; Talc; Crospovidone; Povidone k30; Silicon dioxide; Blackberry; Cellulose, microcrystalline
|
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| Dosage Form | Chewable Tablet | |||||
| Company | Alembic Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Saccharin sodium dihydrate; Magnesium stearate; Mannitol; Talc; Crospovidone; Silicon dioxide; Black currant; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Chewable Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Saccharin sodium dihydrate | DIG Info | Carbonic anhydrase XII (Ki = 633 nM) | [12] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Acesulfame potassium; Aspartame; Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline
|
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| Dosage Form | Chewable Tablet | |||||
| Company | Jubilant Cadista Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Acesulfame | DIG Info | Carbonic anhydrase IX (Ki = 2400 nM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Aspartame; Magnesium stearate; Mannitol; Croscarmellose sodium; Silicon dioxide; Black currant; Cellulose, microcrystalline; Tribasic calcium phosphate
|
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| Dosage Form | Chewable Tablet | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Talc; Croscarmellose sodium; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Saccharin sodium
|
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| Dosage Form | Chewable Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Talc; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Povidone k29/32; Saccharin sodium
|
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| Dosage Form | Chewable Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Sodium stearyl fumarate; Mannitol; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Saccharin sodium; Sodium starch glycolate type a potato; Starch, corn
|
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| Dosage Form | Chewable Tablet | |||||
| Company | AvKARE; Avera McKennan Hospital; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [10] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Sodium stearyl fumarate; Mannitol; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose; Saccharin sodium; Sodium starch glycolate type a potato; Starch, corn
|
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| Dosage Form | Chewable Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [10] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Mannitol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | TruPharma; Wilshire Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Diethyl phthalate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Polyethylene glycol 400; Hypromellose 2910 (6 mpa.s); Hypromellose phthalate (31% phthalate, 40 cst)
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Croscarmellose sodium; Povidone k30; Cellulose, microcrystalline
|
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| Dosage Form | Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline; Povidones; Saccharin sodium; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Chewable Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline; Saccharin sodium
|
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| Dosage Form | Chewable Tablet | |||||
| Company | Taro Pharmaceuticals USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Aspartame; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Povidone k25; Sodium starch glycolate type b potato
|
|||||
| Dosage Form | Chewable Tablet | |||||
| Company | Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Diethyl phthalate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Sucralose; Magnesium stearate; Magnesium carbonate; Povidone k30; Cellulose, microcrystalline; Polacrilin potassium
|
|||||
| Dosage Form | Chewable Tablet | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Sucralose; Magnesium stearate; Magnesium carbonate; Povidone k30; Microcrystalline cellulose; Polacrilin potassium
|
|||||
| Dosage Form | Chewable Tablet | |||||
| Company | Rising Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Ascend Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Talc; Hydroxypropyl cellulose; Powdered cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Calcium carbonate; Magnesium stearate; Magnesium aluminum silicate; Hydroxypropyl cellulose, low substituted; Povidones; Saccharin sodium; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Chewable Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Calcium carbonate | DIG Info | Carbonic anhydrase IX (Ki = 8600 nM) | [14] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Sucralose; Mannitol; Crospovidone (15 mpa.s at 5%); Ethylcellulose (100 mpa.s)
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Crospovidone; Povidone; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Silicon dioxide; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:2)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Crospovidone; Cellulose, microcrystalline; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Magnesium stearate; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Povidone k25
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Povidone k30; Silicon dioxide; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack; St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Povidone k30; Silicon dioxide; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | H. J. Harkins Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 35 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Povidone; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Alembic Pharmaceuticals; NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 36 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | McKesson; NCS HealthCare of KY, Inc dba Vangard Labs; Physicians Total Care; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Povidone; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 38 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Povidone; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare; NCS HealthCare of KY, Inc dba Vangard Labs; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 39 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Povidone; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Hikma Pharmaceutical; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Physicians Total Care; West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 40 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Povidones; Sodium starch glycolate type a potato; Starch, corn
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 41 |
DFM Info
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|||||
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Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 42 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Povidone k30; Colloidal silicon dioxide; Sodium starch glycolate type a potato
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cipla | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 43 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Povidone k30; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 44 |
DFM Info
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|||||
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Ferric oxide red; Ferric oxide yellow; Silicon dioxide; Hypromelloses; Methacrylic acid
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 45 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Povidone k29/32; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Proficient Rx; State of Florida DOH Central Pharmacy; TYA Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 46 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Povidone k29/32; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack; Unichem Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 47 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Povidones; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging; McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 48 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Microcrystalline cellulose; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 49 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 50 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 51 |
DFM Info
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|||||
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Magnesium stearate; Povidone k30; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydroxypropyl cellulose, low substituted; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 52 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Cellulose, microcrystalline; Povidones; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 53 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Cellulose, microcrystalline; Povidones; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Lamotrigine 50 mg tablet | Click to Show/Hide the Full List of Formulation(s): 12 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sucralose; Aspartame; Magnesium stearate; Mannitol; Crospovidone; Povidone; Silicon dioxide; Dextrose; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Polyvinyl acetate; Starch, corn; Tricalcium phosphate
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; ScieGen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Stearic acid; Aspartame; Magnesium stearate; Mannitol; Sodium chloride; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Starch, corn
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Impax Generics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [4] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Sodium stearyl fumarate; Sucralose; Magnesium stearate; Mannitol; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Peppermint; Starch, corn
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Glyceryl monostearate; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Hypromelloses; Methacrylic acid
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:2)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [4] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Mannitol; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | TruPharma; Wilshire Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Lactose monohydrate; Diethyl phthalate; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Polyethylene glycol 400; Hypromellose 2910 (6 mpa.s); Hypromellose phthalate (31% phthalate, 40 cst)
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Diethyl phthalate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols
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|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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Sucralose; Mannitol; Crospovidone (15 mpa.s at 5%); Ethylcellulose (100 mpa.s)
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|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; NorthStar Rx; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Povidone; Cellulose, microcrystalline; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Silicon dioxide; Hypromelloses; Methacrylic acid
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Par Pharmaceutical; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Lamotrigine 250 mg tablet | Click to Show/Hide the Full List of Formulation(s): 4 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; Cochineal; Fd&c blue no. 2; Glyceryl monostearate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Polysorbate 80; Hypromelloses; Methacrylic acid
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Caprylic acid | DIG Info | GPCR84 receptor (Ki = 19600 nM) | [7] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Drug Formulation 2 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Tricaprin; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Silicon dioxide; Copovidone; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:2); Polydextrose
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Tricaprin | DIG Info | Protein kinase C (IC50 = 10000 nM) | [13] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Povidone; Cellulose, microcrystalline; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Silicon dioxide; Hypromelloses; Methacrylic acid
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Lamotrigine 300 mg tablet | Click to Show/Hide the Full List of Formulation(s): 6 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:2)
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [4] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [11] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; Glyceryl monostearate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Polysorbate 80; Hypromelloses; Methacrylic acid
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Diethyl phthalate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories; NorthStar Rx; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [9] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Ferrosoferric oxide; Silicon dioxide; Hypromellose, unspecified; Methacrylic acid
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Ferrosoferric oxide; Silicon dioxide; Hypromelloses; Methacrylic acid
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Lamotrigine 5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 13 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Aspartame; Magnesium stearate; Mannitol; Talc; Crospovidone; Povidone k30; Silicon dioxide; Blackberry; Cellulose, microcrystalline
|
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| Dosage Form | Chewable Tablet | |||||
| Company | Alembic Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Saccharin sodium dihydrate; Magnesium stearate; Mannitol; Talc; Crospovidone; Silicon dioxide; Black currant; Cellulose, microcrystalline; Starch, corn
|
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| Dosage Form | Chewable Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Saccharin sodium dihydrate | DIG Info | Carbonic anhydrase XII (Ki = 633 nM) | [12] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Acesulfame potassium; Aspartame; Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline
|
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| Dosage Form | Chewable Tablet | |||||
| Company | Jubilant Cadista Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Acesulfame | DIG Info | Carbonic anhydrase IX (Ki = 2400 nM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Aspartame; Magnesium stearate; Mannitol; Croscarmellose sodium; Silicon dioxide; Black currant; Cellulose, microcrystalline; Tribasic calcium phosphate
|
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| Dosage Form | Chewable Tablet | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Talc; Croscarmellose sodium; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Saccharin sodium
|
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| Dosage Form | Chewable Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Sodium stearyl fumarate; Mannitol; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Saccharin sodium; Sodium starch glycolate type a potato; Starch, corn
|
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| Dosage Form | Chewable Tablet | |||||
| Company | AvKARE; Carilion Materials Management | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [10] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Sodium stearyl fumarate; Mannitol; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose; Saccharin sodium; Sodium starch glycolate type a potato; Starch, corn
|
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| Dosage Form | Chewable Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [10] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline; Povidones; Saccharin sodium; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Chewable Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline; Saccharin sodium
|
|||||
| Dosage Form | Chewable Tablet | |||||
| Company | Taro Pharmaceuticals USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Aspartame; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Povidone k25; Sodium starch glycolate type b potato
|
|||||
| Dosage Form | Chewable Tablet | |||||
| Company | Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Sucralose; Magnesium stearate; Magnesium carbonate; Povidone k30; Cellulose, microcrystalline; Polacrilin potassium
|
|||||
| Dosage Form | Chewable Tablet | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Sucralose; Magnesium stearate; Magnesium carbonate; Povidone k30; Microcrystalline cellulose; Polacrilin potassium
|
|||||
| Dosage Form | Chewable Tablet | |||||
| Company | Rising Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Calcium carbonate; Magnesium stearate; Magnesium aluminum silicate; Hydroxypropyl cellulose, low substituted; Povidones; Saccharin sodium; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Chewable Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Calcium carbonate | DIG Info | Carbonic anhydrase IX (Ki = 8600 nM) | [14] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Lamotrigine 150 mg tablet | Click to Show/Hide the Full List of Formulation(s): 21 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Magnesium stearate; Mannitol; Ferric oxide yellow; Croscarmellose sodium; Povidone k30; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Ascend Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Croscarmellose sodium; Crospovidone; Povidone; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Croscarmellose sodium; Crospovidone; Cellulose, microcrystalline; Povidones
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| Dosage Form | Oral Tablet | |||||
| Company | Clinical Solutions Wholesale; Taro Pharmaceuticals USA; Upsher-Smith Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide yellow; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Povidone k25
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| Dosage Form | Oral Tablet | |||||
| Company | Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Povidone k30; Silicon dioxide; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs; Physicians Total Care; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Povidone; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Alembic Pharmaceuticals; NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Ferric oxide yellow; Povidone; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Ferric oxide yellow; Povidone; Cellulose, microcrystalline; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Hikma Pharmaceutical; West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Povidone; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Povidone; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide yellow; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Povidone k30; Colloidal silicon dioxide; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Cipla | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Povidone k30; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide yellow; Povidone k30; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydroxypropyl cellulose, low substituted; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Ferric oxide yellow; Cellulose, microcrystalline; Povidones; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Povidone k29/32; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack; Unichem Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Povidones; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Lamotrigine 2 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Calcium carbonate; Magnesium stearate; Magnesium aluminum silicate; Hydroxypropyl cellulose, low substituted; Povidones; Saccharin sodium; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Chewable Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Calcium carbonate | DIG Info | Carbonic anhydrase IX (Ki = 8600 nM) | [14] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
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