Details of the Active Pharmaceutical Ingredient (API)

General Information of API (ID: D00527)
Name	Phentermine
Synonyms	Click to Show/Hide the Synonyms of This API phentermine; 122-09-8; 2-methyl-1-phenylpropan-2-amine; Duromine; 1,1-Dimethyl-2-phenylethylamine; Ionamin; alpha,alpha-Dimethylphenethylamine; Phenterminum; Fentermina; Mirapront; Lipopill; Fastin; Adipex-P; 2-Phenyl-tert-butylamine; Benzeneethanamine, alpha,alpha-dimethyl-; Phentermine resin; UNII-C045TQL4WP; Normephentermine; Benzeneethanamine, .alpha.,.alpha.-dimethyl-; Lonamin; Omnibex; C045TQL4WP; CHEMBL1574; CHEBI:8080; 122-09-8 (free base); Obermine; Phentrol; Phentrol 2; Phentrol 3; Phentrol 4; DEA No. 1640; 1,1-DIMETHYL-2-PHENYL-ETHYLAMINE; Phenyl-tert-butylamine; alpha-Benzylisopropylamine; Phenyl-tertiary-butylamine; Fentermina [INN-Spanish]; Phenterminum [INN-Latin]; Phentermine [USAN:INN:BAN]; Phentermine resin complex; 2-Amino-2-methyl-1-phenylpropane; RCRA waste number P046; alpha,alpha-Dimethylbenzeneethanamine; alpha,alpha-Dimethyl-beta-phenylethylamine; HSDB 3158; SR-05000001805; (alpha,alpha)-Dimethylphenethylamine; EINECS 204-522-1; Ethanamine, 1,1-dimethyl-2-phenyl-; Phentermine (USAN/INN); RCRA waste no. P046; BRN 0970319; Phenethylamine, alpha,alpha-dimethyl-; .alpha.,.alpha.-Dimethylphenethylamine; alpha,alpha-Dimethylphenethylamine solution; 1-benzyl-iso-propyl amine; EC 204-522-1; SCHEMBL26615; GTPL7269; DTXSID9023461; HMS2093B16; Pharmakon1600-01505660; Phentermine 0.1 mg/ml in Methanol; Phentermine 1.0 mg/ml in Methanol; ZINC8403947; .alpha..alpha.Dimethylphenethylamine; BDBM50246598; NSC759163; AKOS004123261; AB02355; DB00191; NSC-759163; NCGC00263911-02; Phenethylamine, .alpha.,.alpha.-dimethyl-; SBI-0206817.P001; FT-0716831; C07438; D05458; X-2149; Q418157; SR-05000001805-1; SR-05000001805-2; BRD-K96319534-001-01-7; Phentermine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material
Clinical Status	Approved
Disease Indication	Obesity		ICD-11: 5B81	[1]
PubChem CID	4771
Formula	C10H15N
Canonical SMILES	CC(C)(CC1=CC=CC=C1)N
InChI	1S/C10H15N/c1-10(2,11)8-9-6-4-3-5-7-9/h3-7H,8,11H2,1-2H3
InChIKey	DHHVAGZRUROJKS-UHFFFAOYSA-N
	Click to Show/Hide the Molecular Data (Structure/Property) of This API
Structure	<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=4771"></iframe>
Structure	3D MOL		2D MOL
Physicochemical Properties	Molecular Weight	149.23	Topological Polar Surface Area	26
	XlogP	1.9	Complexity	112
	Heavy Atom Count	11	Rotatable Bond Count	2
	Hydrogen Bond Donor Count	1	Hydrogen Bond Acceptor Count	1

Full List of Drug Formulations (DFMs) Containing This API
Phentermine 15 mg capsule			Click to Show/Hide the Full List of Formulation(s): 13 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 5; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac
Dosage Form	Oral Capsule
Company	Aurolife Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	Hydrazine yellow	DIG Info	GABA(A) receptor alpha-1 (IC50 = 13 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Teva Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Alcohol; Aluminum oxide; Gelatin; Methyl alcohol; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Lannett Company
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Alcohol; Aluminum oxide; Gelatin, unspecified; Methyl alcohol; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Preferred Pharamaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Alcohol; Aluminum oxide; Calcium phosphate, dibasic, anhydrous; Gelatin; Methyl alcohol; Shellac
Dosage Form	Extended Release Oral Capsule
Company	Lannett Company
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Fd&c red no. 3; Silicon dioxide; Gelatin; Starch, corn
Dosage Form	Oral Capsule
Company	Eon Labs
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 7	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Butyl alcohol; Fd&c yellow no. 5; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Fd&c red no. 3; Silicon dioxide; Alcohol; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Leading Pharma; Sunrise Pharmaceutical
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Hydrazine yellow	DIG Info	GABA(A) receptor alpha-1 (IC50 = 13 uM)	[2]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 8	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Fd&c red no. 3
Dosage Form	Oral Capsule
Company	Apotheca; Bryant Ranch Prepack; Physicians Total Care; Rebel Distributors
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 9	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Fd&c red no. 3; Gelatin, unspecified; Starch, tapioca
Dosage Form	Oral Capsule
Company	A-S Medication Solutions; TAGI Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 10	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Fd&c red no. 3; Gelatin; Starch, corn
Dosage Form	Oral Capsule
Company	A-S Medication Solutions; Aidarex Pharmaceuticals; Apotheca; Blenheim Phamacal; Bryant Ranch Prepack; DirectRX; KVK Tech; Northwind Pharmaceuticals; PD-Rx Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 11	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Fd&c red no. 3; Gelatin, unspecified; Starch, corn
Dosage Form	Oral Capsule
Company	Preferred Pharamaceuticals; Proficient Rx; Unit Dose Services
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 12	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Fd&c red no. 3; Silicon dioxide; Gelatin, unspecified; Starch, corn
Dosage Form	Oral Capsule
Company	Unit Dose Services
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 13	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Fd&c red no. 3; Gelatin, unspecified
Dosage Form	Oral Capsule
Company	Preferred Pharamaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Phentermine 30 mg capsule			Click to Show/Hide the Full List of Formulation(s): 27 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Ferrosoferric oxide; Propylene glycol; Sucrose; Titanium dioxide; Polysorbate 80; Alcohol; Aluminum oxide; Gelatin; Hypromelloses; Methyl alcohol; Polyethylene glycols; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	DirectRX
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[2]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; D&c yellow no. 10; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Alcohol; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Rebel Distributors
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Ferrosoferric oxide; Propylene glycol; Sucrose; Titanium dioxide; Polysorbate 80; Alcohol; Aluminum oxide; Gelatin; Hypromelloses; Methyl alcohol; Polyethylene glycols; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Bryant Ranch Prepack; Lannett Company
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Polysorbate 80	DIG Info	Prostaglandin G/H synthase 1 (IC50 = 1 uM)	[2]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Teva Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Alcohol; Aluminum oxide; Gelatin; Methyl alcohol; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Blenheim Phamacal; H. J. Harkins Company; Lannett Company; NuCare Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Alcohol; Aluminum oxide; Gelatin, unspecified; Methyl alcohol; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Unit Dose Services
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 7	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Alcohol; Aluminum oxide; Calcium phosphate, dibasic, anhydrous; Gelatin; Methyl alcohol; Shellac
Dosage Form	Extended Release Oral Capsule
Company	Lannett Company
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 8	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; D&c red no. 28; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Alcohol; Aluminum oxide; Gelatin; Methyl alcohol; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Blenheim Phamacal; Lannett Company; Physicians Total Care; Preferred Pharamaceuticals; Stat Rx USA
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 9	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; D&c red no. 28; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Alcohol; Aluminum oxide; Gelatin, unspecified; Methyl alcohol; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	A-S Medication Solutions; Bryant Ranch Prepack; Unit Dose Services
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 10	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Lactose monohydrate; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Water; Silicon dioxide; Alcohol; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Leading Pharma; Sunrise Pharmaceutical
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[2]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 11	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide yellow; Propylene glycol; Alcohol; Dimethicone; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	PD-Rx Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 12	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide yellow; Propylene glycol; Alcohol; Dimethicone; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Lannett Company; Preferred Pharamaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 13	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Ferric oxide yellow; Titanium dioxide; Crospovidone; Aluminum oxide; Gelatin; Povidones
Dosage Form	Oral Capsule
Company	Apotheca; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Crospovidone	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 14	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Fd&c red no. 3; Gelatin; Starch, corn
Dosage Form	Oral Capsule
Company	Apotheca
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 15	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Dibasic calcium phosphate dihydrate; Ferric oxide yellow; Titanium dioxide; Aluminum oxide; Crospovidone (15 mpa.s at 5%); Gelatin, unspecified; Povidone, unspecified
Dosage Form	Oral Capsule
Company	Preferred Pharamaceuticals; Proficient Rx; Unit Dose Services
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 16	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Ferric oxide yellow; Titanium dioxide; Aluminum oxide; Crospovidone (15 mpa.s at 5%); Gelatin; Povidones
Dosage Form	Oral Capsule
Company	Sun Pharmaceutical Industries
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 17	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Fd&c red no. 3; Silicon dioxide; Gelatin; Starch, corn
Dosage Form	Oral Capsule
Company	Eon Labs
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 18	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Sodium lauryl sulfate; Fd&c blue no. 1; Sucrose; Silicon dioxide; Gelatin; Povidones; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Eon Labs
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[2]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 19	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac
Dosage Form	Oral Capsule
Company	Aurolife Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 20	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Fd&c red no. 3; Gelatin
Dosage Form	Oral Capsule
Company	PD-Rx Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 21	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Fd&c red no. 3; Gelatin, unspecified; Starch, tapioca
Dosage Form	Oral Capsule
Company	TAGI Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 22	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Fd&c red no. 3; Gelatin; Starch, corn
Dosage Form	Oral Capsule
Company	A-S Medication Solutions; Dispensing Solution; KVK Tech; Lake Eire Medical & Surgical Supply DBA Quality Care Products; PD-Rx Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 23	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Fd&c red no. 3; Gelatin, unspecified; Starch, corn
Dosage Form	Oral Capsule
Company	Unit Dose Services
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 24	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Fd&c blue no. 1; Sucrose; Talc; Povidone; Gelatin; Hypromelloses; Starch, corn
Dosage Form	Oral Capsule
Company	PD-Rx Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[2]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[9]
Drug Formulation 25	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Fd&c blue no. 1; Sucrose; Talc; Povidone; Gelatin; Hypromelloses; Starch, corn
Dosage Form	Oral Capsule
Company	A-S Medication Solutions; Apotheca; Blenheim Phamacal; KVK Tech; NuCare Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[2]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[9]
Drug Formulation 26	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Fd&c blue no. 1; Sucrose; Talc; Gelatin, unspecified; Hypromellose, unspecified; Povidone, unspecified; Starch, corn
Dosage Form	Oral Capsule
Company	Unit Dose Services
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[2]
Drug Formulation 27	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Fd&c blue no. 1; Sucrose; Talc; Gelatin; Hypromelloses; Povidones; Starch, corn
Dosage Form	Oral Capsule
Company	Aidarex Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[2]
Phentermine 37.5 mg capsule			Click to Show/Hide the Full List of Formulation(s): 6 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Fd&c red no. 3; Silicon dioxide; Alcohol; Gelatin; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Leading Pharma; Sunrise Pharmaceutical
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[4]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; D&c red no. 33; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Alcohol; Gelatin; Methyl alcohol; Shellac
Dosage Form	Oral Capsule
Company	Epic Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	D&C red no. 33	DIG Info	Solute carrier SLCO2B1 (Ki = 58.1 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Alcohol; Aluminum oxide; Gelatin; Hypromelloses; Methyl alcohol; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Lannett Company; Physicians Total Care
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 33; Fd&c blue no. 1; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Gelatin, unspecified; Shellac; Starch, corn
Dosage Form	Oral Capsule
Company	Teva Select Brands
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	D&C red no. 33	DIG Info	Solute carrier SLCO2B1 (Ki = 58.1 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 33; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Gelatin; Starch, corn
Dosage Form	Oral Capsule
Company	A-S Medication Solutions; Aidarex Pharmaceuticals; Apotheca; Blenheim Phamacal; Bryant Ranch Prepack; KVK Tech; PD-Rx Pharmaceuticals; Unit Dose Services
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	D&C red no. 33	DIG Info	Solute carrier SLCO2B1 (Ki = 58.1 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 33; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Gelatin, unspecified; Starch, corn
Dosage Form	Oral Capsule
Company	A-S Medication Solutions
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	D&C red no. 33	DIG Info	Solute carrier SLCO2B1 (Ki = 58.1 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Phentermine 15 mg tablet			Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Sucralose; Fd&c blue no. 1; Fd&c yellow no. 5; Magnesium stearate; Mannitol; Citric acid monohydrate; Talc; Povidone k30; Peppermint; Povidones
Dosage Form	Disintegrating Oral Tablet
Company	Akrimax Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sucralose	DIG Info	Carbonic anhydrase II (Ki = 300 nM)	[7]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Hydrazine yellow	DIG Info	GABA(A) receptor alpha-1 (IC50 = 13 uM)	[2]
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	Mannitol	DIG Info	Glycine receptor alpha-1 (EC50 = 12589.25 nM)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Phentermine 30 mg tablet			Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Sucralose; Fd&c yellow no. 5; Magnesium stearate; Mannitol; Citric acid monohydrate; Talc; Povidone k30; Peppermint; Povidones
Dosage Form	Disintegrating Oral Tablet
Company	Akrimax Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sucralose	DIG Info	Carbonic anhydrase II (Ki = 300 nM)	[7]
	Hydrazine yellow	DIG Info	GABA(A) receptor alpha-1 (IC50 = 13 uM)	[2]
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	Mannitol	DIG Info	Glycine receptor alpha-1 (EC50 = 12589.25 nM)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Phentermine 37.5 mg tablet			Click to Show/Hide the Full List of Formulation(s): 33 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Sucralose; Fd&c blue no. 1; Magnesium stearate; Mannitol; Citric acid monohydrate; Talc; Povidone k30; Peppermint; Povidones
Dosage Form	Disintegrating Oral Tablet
Company	Akrimax Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sucralose	DIG Info	Carbonic anhydrase II (Ki = 300 nM)	[7]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	Mannitol	DIG Info	Glycine receptor alpha-1 (EC50 = 12589.25 nM)	[8]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 1; Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Propylene glycol; Titanium dioxide; Crospovidone; Povidone; Shellac
Dosage Form	Oral Tablet
Company	Stat Rx USA
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[9]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Crospovidone	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 1; Magnesium stearate; Dibasic calcium phosphate dihydrate; Propylene glycol; Titanium dioxide; Crospovidone; Povidone; Shellac
Dosage Form	Oral Tablet
Company	Physicians Total Care
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[9]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Crospovidone	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 1; Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Propylene glycol; Titanium dioxide; Crospovidone; Povidones; Shellac
Dosage Form	Oral Tablet
Company	Apotheca; Bryant Ranch Prepack; Unit Dose Services
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[5]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Crospovidone	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Sucrose; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
Dosage Form	Oral Tablet
Company	Leading Pharma; Sunrise Pharmaceutical
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Stearic acid	DIG Info	Phosphodiesterase 3A (IC50 = 3.1 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Stearic acid; Anhydrous lactose; Fd&c blue no. 1; Magnesium stearate; Sucrose; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
Dosage Form	Oral Tablet
Company	Ingenus Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Stearic acid	DIG Info	Phosphodiesterase 3A (IC50 = 3.1 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 7	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Stearic acid; Anhydrous lactose; Fd&c blue no. 1; Magnesium stearate; Sucrose; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
Dosage Form	Oral Tablet
Company	Rising Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Stearic acid	DIG Info	Phosphodiesterase 3A (IC50 = 3.1 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 8	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Fd&c blue no. 1; Magnesium stearate; Sucrose; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
Dosage Form	Oral Tablet
Company	Aurolife Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Crospovidone	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 9	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 1; Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Crospovidone; Povidone
Dosage Form	Oral Tablet
Company	Aidarex Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[9]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Crospovidone	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 10	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Stearic acid; Anhydrous lactose; Magnesium stearate; Sucrose; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
Dosage Form	Oral Tablet
Company	Mikah Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Stearic acid	DIG Info	Phosphodiesterase 3A (IC50 = 3.1 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 11	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Sucrose; Cellulose, microcrystalline; Shellac; Starch, corn
Dosage Form	Oral Tablet
Company	Life Line Home Care Services
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Stearic acid	DIG Info	Phosphodiesterase 3A (IC50 = 3.1 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 12	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Sucrose; Povidone, unspecified; Starch, corn
Dosage Form	Oral Tablet
Company	Bryant Ranch Prepack
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Stearic acid	DIG Info	Phosphodiesterase 3A (IC50 = 3.1 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 13	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Sucrose; Povidones; Starch, corn
Dosage Form	Oral Tablet
Company	Bryant Ranch Prepack; Qualitest Pharmaceuticals; Solco Healthcare
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Stearic acid	DIG Info	Phosphodiesterase 3A (IC50 = 3.1 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 14	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Stearic acid; Anhydrous lactose; Magnesium stearate; Sucrose; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
Dosage Form	Oral Tablet
Company	Elite Laboratories
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Stearic acid	DIG Info	Phosphodiesterase 3A (IC50 = 3.1 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 15	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Sucrose; Cellulose, microcrystalline; Shellac; Starch, corn
Dosage Form	Oral Tablet
Company	American Health Packaging
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Stearic acid	DIG Info	Phosphodiesterase 3A (IC50 = 3.1 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 16	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Sucrose; Cellulose, microcrystalline; Starch, corn
Dosage Form	Oral Tablet
Company	A-S Medication Solutions; Aidarex Pharmaceuticals; Blenheim Phamacal; Bryant Ranch Prepack; KVK Tech; Lake Eire Medical & Surgical Supply DBA Quality Care Products; PD-Rx Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Stearic acid	DIG Info	Phosphodiesterase 3A (IC50 = 3.1 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 17	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Stearic acid; Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Sucrose; Microcrystalline cellulose; Starch, corn
Dosage Form	Oral Tablet
Company	Unit Dose Services
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Stearic acid	DIG Info	Phosphodiesterase 3A (IC50 = 3.1 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 18	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Fd&c blue no. 1; Magnesium stearate; Sucrose; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Starch, corn
Dosage Form	Oral Tablet
Company	Proficient Rx
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 19	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 1; Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Crospovidone; Povidones
Dosage Form	Oral Tablet
Company	NuCare Pharmaceuticals; PD-Rx Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Crospovidone	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 20	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose, anhydrous; Fd&c blue no. 1; Magnesium stearate; Sucrose; Cellulose, microcrystalline; Starch, corn; Starch, corn
Dosage Form	Oral Tablet
Company	Physicians Total Care
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 21	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Fd&c blue no. 1; Magnesium stearate; Sucrose; Aluminum oxide; Cellulose, microcrystalline; Starch, corn
Dosage Form	Oral Tablet
Company	Aidarex Pharmaceuticals; DirectRX; Lannett Company; PD-Rx Pharmaceuticals; Proficient Rx
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 22	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Fd&c blue no. 1; Magnesium stearate; Sucrose; Cellulose, microcrystalline; Starch, corn
Dosage Form	Oral Tablet
Company	A-S Medication Solutions
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 23	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Fd&c blue no. 1; Magnesium stearate; Sucrose; Aluminum oxide; Microcrystalline cellulose; Starch, corn
Dosage Form	Oral Tablet
Company	Preferred Pharamaceuticals; Unit Dose Services
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 24	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Fd&c blue no. 1; Magnesium stearate; Sucrose; Microcrystalline cellulose; Starch, corn
Dosage Form	Oral Tablet
Company	PD-Rx Pharmaceuticals; Teva Select Brands
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 25	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 1; Magnesium stearate; Dibasic calcium phosphate dihydrate; Crospovidone (15 mpa.s at 5%); Povidone, unspecified
Dosage Form	Oral Tablet
Company	A-S Medication Solutions; Unit Dose Services
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 26	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 1; Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Crospovidone (15 mpa.s at 5%); Povidones
Dosage Form	Oral Tablet
Company	Sun Pharmaceutical Industries
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 27	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 1; Magnesium stearate; Sucrose; Cellulose, microcrystalline; Starch, corn
Dosage Form	Oral Tablet
Company	Polygen Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 28	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Invert sugar; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline
Dosage Form	Oral Tablet
Company	Legacy Pharmaceutical
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Carmellose sodium	DIG Info	Albendazole monooxygenase (Protein expression upregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 29	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Cellulose, microcrystalline
Dosage Form	Oral Tablet
Company	Mas Management Group; PD-Rx Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Carmellose sodium	DIG Info	Albendazole monooxygenase (Protein expression upregulation)	[6]
Drug Formulation 30	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Colloidal silicon dioxide; Maize invert sugar
Dosage Form	Oral Tablet
Company	Camber Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Carmellose sodium	DIG Info	Albendazole monooxygenase (Protein expression upregulation)	[6]
Drug Formulation 31	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
Dosage Form	Oral Tablet
Company	Teva Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 32	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Microcrystalline cellulose
Dosage Form	Oral Tablet
Company	Preferred Pharamaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Carmellose sodium	DIG Info	Albendazole monooxygenase (Protein expression upregulation)	[6]
Drug Formulation 33	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Povidone
Dosage Form	Oral Tablet
Company	Keltman Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Povidone	DIG Info	Cholesterol 25-hydroxylase (IC50 = 78.3 uM)	[9]
Phentermine 8 mg tablet			Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Stearic acid; Fd&c blue no. 1; Magnesium stearate; Sucrose; Cellulose, microcrystalline; Starch, corn
Dosage Form	Oral Tablet
Company	KVK Tech
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Stearic acid	DIG Info	Phosphodiesterase 3A (IC50 = 3.1 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]

References
1	FDA label for approved phentermine from the official website of the U.S. Food and Drug Administration.
2	The activities of drug inactive ingredients on biological targets. Science. 2020 Jul 24;369(6502):403-413.
3	Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16009-16018.
4	Synthesis and evaluation of dihydropyrroloquinolines that selectively antagonize P-glycoprotein. J Med Chem. 2004 Mar 11; 47(6):1413-22.
5	Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration. Eur J Pharm Biopharm. 2008 Sep;70(1):279-88.
6	Effects of commonly used excipients on the expression of CYP3A4 in colon and liver cells. Pharm Res. 2010 Aug;27(8):1703-12.
7	Sweet Binders: Carbonic Anhydrase IX in Complex with Sucralose. ACS Med Chem Lett. 2018 May 10; 9(7):657-661.
8	Pharmacological property optimization for allosteric ligands: A medicinal chemistry perspective. Bioorg Med Chem Lett. 2017 Jun 1; 27(11):2239-2258.
9	Mediation of in vitro cytochrome p450 activity by common pharmaceutical excipients. Mol Pharm. 2013 Jul 1;10(7):2739-48.

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