Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00660) | |||||
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| Name |
Temozolomide
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| Synonyms |
Click to Show/Hide the Synonyms of This API
temozolomide; 85622-93-1; Methazolastone; Temodal; Temodar; Temozolamide; 3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide; Temozolomidum [Latin]; Sch 52365; Temozolodida [Spanish]; Temozolomidum; CCRG 81045; CCRG-81045; NSC 362856; Sch-52365; M&B 39831; M&B-39831; CCRIS 8996; NSC-362856; MB 39831; 8-Carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one; UNII-YF1K15M17Y; M & B 39831; BRN 5547136; 3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-1,2,3,5-tetrazine-8-carboxamide; 3-Methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide; NSC362856; CHEMBL810; M-39831; 3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamide; MLS002701861; YF1K15M17Y; CHEBI:72564; 3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide; MFCD00866492; NCGC00167429-01; Temozolodida; 3-methyl-4-oxo-3H,4H-imidazo[4,3-d][1,2,3,5]tetrazine-8-carboxamide; 3,4-dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide; 4-methyl-5-oxo-2,3,4,6,8-pentazabicyclo[4.3.0]nona-2,7,9-triene-9-carboxamide; DSSTox_CID_23714; DSSTox_RID_80068; DSSTox_GSID_43714; 3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide; 3-Methyl-4-oxo-3,4-dihydroimidazo-[5,1-d][1,2,3,5]tetrazine-8-carboxamide; 3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide.; 8-CARBAMOYL-3-METHYLIMIDAZO[5,1-D]-1,2,3,5-TETRAZIN-4(3H)-ONE; SMR000466338; Temodal (TN); Temodar (TN); CAS-85622-93-1; Temozolomide, VETRANAL(TM), analytical standard; SR-01000759347; temozolomida; Temozolomide (JAN/USAN/INN); Temozolomide [USAN:INN:BAN]; zlchem 2; 3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide; PubChem17413; Temodar (TN) (Schering); SCHEMBL3739; MLS000759447; MLS001424028; BIDD:GT0204; GTPL7301; DTXSID5043714; AOB1657; Temozolomide, >=98% (HPLC); ZLA0002; HMS2051O12; HMS2090B08; HMS2232N13; HMS3264I14; HMS3269P05; HMS3372K13; HMS3393O12; HMS3413D06; HMS3654N05; HMS3677D06; HMS3713H16; Pharmakon1600-01502289; 3-methyl-4-oxo-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide; ALBB-021358; BCP03692; ZINC1482184; Tox21_112433; AC-758; ANW-43023; BDBM50034562; CT0139; DL-190; NSC759883; STK623541; 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetraazine-8-carboxamide; AKOS005557098; Tox21_112433_1; CCG-100870; CS-0943; DB00853; KS-1216; MCULE-9414994158; NC00120; NSC-759883; Imidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo-; NCGC00167429-02; NCGC00167429-04; NCGC00167429-05; AK-72945; BP-25388; BR-72945; HY-17364; NCI60_003316; BCP0726000154; AB0007590; Temozolomide 100 microg/mL in Acetonitrile; AM20110227; FT-0630936; FT-0674845; SW197500-4; D06067; M-2350; AB00639915-06; AB00639915-08; AB00639915-09; AB00639915_10; AB00639915_11; 199366-EP2275425A1; 622T931; A841386; Q425088; Q-201786; SR-01000759347-4; SR-01000759347-5; BRD-K32107296-001-04-5; Z1551429743; 3-methyl-4-oxo-8-imidazo[5,1-d][1,2,3,5]tetrazinecarboxamide; 3-methyl-8-carbamoyl-imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one; Temozolomide, United States Pharmacopeia (USP) Reference Standard; 3-methyl-4-oxidanylidene-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide; 3-METHYL-4-OXO-8-IMIDAZOLO[5,1-D][1,2,3,5]TETRAZINECARBOXAMIDE; 3-Methyl-8-aminocarbonyl-imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one; Imidazo[5,2,3,5-tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo-; {Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide,} 3, 4-dihydro-3-methyl-4-oxo-; Temozolomide, Pharmaceutical Secondary Standard; Certified Reference Material
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| Clinical Status |
Approved
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| Disease Indication | Brain cancer | ICD-11: 2A00 | [1] | ||
| PubChem CID | |||||
| Formula |
C6H6N6O2
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| Canonical SMILES |
CN1C(=O)N2C=NC(=C2N=N1)C(=O)N
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| InChI |
1S/C6H6N6O2/c1-11-6(14)12-2-8-3(4(7)13)5(12)9-10-11/h2H,1H3,(H2,7,13)
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| InChIKey |
BPEGJWRSRHCHSN-UHFFFAOYSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=5394"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 194.15 | Topological Polar Surface Area | 106 | |
| XlogP | -1.1 | Complexity | 315 | ||
| Heavy Atom Count | 14 | Rotatable Bond Count | 1 | ||
| Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 5 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
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| Temozolomide 20 mg capsule | Click to Show/Hide the Full List of Formulation(s): 18 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Anhydrous citric acid; Stearic acid; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Mannitol; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Alcohol; Aluminum oxide; Gelatin; Methyl alcohol; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Lannett Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Kyselina citronova | DIG Info | Perilipin-1 (IC50 = 3708 nM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [5] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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Stearic acid; Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Tartaric acid; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Amneal Pharmaceuticals; AvPAK | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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Stearic acid; Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Fd&c yellow no. 6; Tartaric acid; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Gelatin; Povidone k29/32; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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Methylparaben; Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Fd&c yellow no. 6; Propylparaben; Tartaric acid; Titanium dioxide; Water; Silicon dioxide; Gelatin; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | IDT Australia | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [9] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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Stearic acid; Anhydrous lactose; Methylparaben sodium; Propylparaben sodium; Sodium lauryl sulfate; Fd&c yellow no. 6; Tartaric acid; Titanium dioxide; Water; Silicon dioxide; Gelatin, unspecified; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Mayne Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium methylparaben | DIG Info | Estrogen receptor beta (EC50 = 1860 nM) | [10] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propylparaben sodium | DIG Info | Estrogen receptor alpha (EC50 = 38200 nM) | [10] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Butyl alcohol; Isopropyl alcohol; Tartaric acid; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type b potato
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| Dosage Form | Oral Capsule | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Butyl alcohol; Isopropyl alcohol; Tartaric acid; Ammonia; Ferric oxide red; Ferric oxide yellow; Potassium hydroxide; Propylene glycol; Water; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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Stearic acid; Anhydrous lactose; Butyl alcohol; Isopropyl alcohol; Tartaric acid; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Lannett Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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Stearic acid; Anhydrous lactose; Butyl alcohol; Isopropyl alcohol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato; Tartaric acid, dl-
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| Dosage Form | Oral Capsule | |||||
| Company | Amerigen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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Anhydrous lactose; Fd&c yellow no. 5; Fd&c yellow no. 6; Magnesium stearate; Tartaric acid; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Isobutyl alcohol; Titanium dioxide; Silicon dioxide; Alcohol; Gelatin; Polyethylene glycols; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Roxane Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Tartaric acid; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 12 |
DFM Info
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Butyl alcohol; Tartaric acid; Ammonia; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a corn
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| Dosage Form | Oral Capsule | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Sodium lauryl sulfate; Butyl alcohol; Isopropyl alcohol; Ammonia; Ferric oxide red; Ferric oxide yellow; Potassium hydroxide; Propylene glycol; Water; Alcohol; Gelatin, unspecified; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Merck Sharp & Dohme | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 14 |
DFM Info
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Sodium lauryl sulfate; Butyl alcohol; Isopropyl alcohol; Ammonia; Ferric oxide red; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Alcohol; Gelatin, unspecified; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 15 |
DFM Info
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Stearic acid; Anhydrous lactose; Tartaric acid; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Silicon dioxide; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Accord Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 16 |
DFM Info
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Stearic acid; Anhydrous lactose; Tartaric acid; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Gelatin; Sodium starch glycolate type a corn
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| Dosage Form | Oral Capsule | |||||
| Company | Lotus Pharmaceutical; Rising Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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Stearic acid; Anhydrous lactose; Tartaric acid; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Gelatin; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Ascend Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 18 |
DFM Info
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Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Gelatin; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Chemi Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Temozolomide 5 mg capsule | Click to Show/Hide the Full List of Formulation(s): 18 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Anhydrous citric acid; Stearic acid; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Alcohol; Aluminum oxide; Gelatin; Methyl alcohol; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Lannett Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Kyselina citronova | DIG Info | Perilipin-1 (IC50 = 3708 nM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [5] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Tartaric acid; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Fd&c red no. 3; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type b potato
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| Dosage Form | Oral Capsule | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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Stearic acid; Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Tartaric acid; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Amneal Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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Stearic acid; Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c yellow no. 6; Tartaric acid; Ammonia; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Aluminum oxide; Gelatin; Povidone k29/32; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Butyl alcohol; Fd&c blue no. 2; Isopropyl alcohol; Tartaric acid; Ammonia; Ferric oxide red; Ferric oxide yellow; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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Methylparaben; Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 1; Propylparaben; Tartaric acid; Ferric oxide yellow; Titanium dioxide; Water; Silicon dioxide; Gelatin; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | IDT Australia | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [9] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Methylparaben sodium; Propylparaben sodium; Sodium lauryl sulfate; Fd&c blue no. 1; Tartaric acid; Ferric oxide yellow; Titanium dioxide; Water; Silicon dioxide; Gelatin, unspecified; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Mayne Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium methylparaben | DIG Info | Estrogen receptor beta (EC50 = 1860 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propylparaben sodium | DIG Info | Estrogen receptor alpha (EC50 = 38200 nM) | [10] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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Stearic acid; Anhydrous lactose; Butyl alcohol; Fd&c blue no. 2; Isopropyl alcohol; Tartaric acid; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Lannett Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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Stearic acid; Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato; Tartaric acid, dl-
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| Dosage Form | Oral Capsule | |||||
| Company | Amerigen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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Anhydrous lactose; Fd&c blue no. 1; Fd&c yellow no. 5; Fd&c yellow no. 6; Magnesium stearate; Tartaric acid; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Isobutyl alcohol; Titanium dioxide; Silicon dioxide; Alcohol; Gelatin; Polyethylene glycols; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Roxane Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Tartaric acid; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 12 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Alcohol; Gelatin, unspecified; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Sodium lauryl sulfate; Butyl alcohol; Fd&c blue no. 2; Isopropyl alcohol; Ammonia; Ferric oxide red; Ferric oxide yellow; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Alcohol; Gelatin, unspecified; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Merck Sharp & Dohme | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Butyl alcohol; Fd&c blue no. 1; Tartaric acid; Ammonia; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a corn
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| Dosage Form | Oral Capsule | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Fd&c blue no. 2; Tartaric acid; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Silicon dioxide; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Accord Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 16 |
DFM Info
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Stearic acid; Anhydrous lactose; Fd&c blue no. 2; Tartaric acid; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Gelatin; Sodium starch glycolate type a corn
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|||||
| Dosage Form | Oral Capsule | |||||
| Company | Lotus Pharmaceutical; Rising Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Fd&c blue no. 2; Tartaric acid; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Gelatin; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Ascend Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Fd&c blue no. 2; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Gelatin; Shellac
|
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| Dosage Form | Oral Capsule | |||||
| Company | Chemi Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Temozolomide 100 mg capsule | Click to Show/Hide the Full List of Formulation(s): 18 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Anhydrous citric acid; Stearic acid; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Mannitol; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Alcohol; Aluminum oxide; Gelatin; Methyl alcohol; Shellac
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Lannett Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Kyselina citronova | DIG Info | Perilipin-1 (IC50 = 3708 nM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [5] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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Stearic acid; Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Tartaric acid; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Capsule | |||||
| Company | Amneal Pharmaceuticals; AvPAK | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Butyl alcohol; Isopropyl alcohol; Tartaric acid; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Fd&c red no. 3; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type b potato
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| Dosage Form | Oral Capsule | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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Stearic acid; Anhydrous lactose; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato; Tartaric acid, dl-
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| Dosage Form | Oral Capsule | |||||
| Company | Amerigen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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Stearic acid; Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c yellow no. 6; Tartaric acid; Propylene glycol; Sodium hydroxide; Titanium dioxide; Silicon dioxide; Aluminum oxide; Gelatin; Povidone k29/32; Povidones; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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Methylparaben; Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Fd&c red no. 40; Propylparaben; Tartaric acid; Titanium dioxide; Water; Silicon dioxide; Gelatin; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | IDT Australia | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [9] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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Stearic acid; Anhydrous lactose; Methylparaben sodium; Propylparaben sodium; Sodium lauryl sulfate; Fd&c red no. 40; Tartaric acid; Titanium dioxide; Water; Silicon dioxide; Gelatin, unspecified; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Mayne Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium methylparaben | DIG Info | Estrogen receptor beta (EC50 = 1860 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylparaben sodium | DIG Info | Estrogen receptor alpha (EC50 = 38200 nM) | [10] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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Stearic acid; Anhydrous lactose; Butyl alcohol; Fd&c blue no. 2; Isopropyl alcohol; Tartaric acid; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Lannett Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Butyl alcohol; Isopropyl alcohol; Tartaric acid; Ammonia; Ferric oxide red; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Tartaric acid; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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Anhydrous lactose; Fd&c red no. 40; Fd&c yellow no. 5; Magnesium stearate; Tartaric acid; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Isobutyl alcohol; Titanium dioxide; Silicon dioxide; Alcohol; Gelatin; Polyethylene glycols; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Roxane Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 12 |
DFM Info
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Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Isopropyl alcohol; Propylene glycol; Sodium hydroxide; Titanium dioxide; Alcohol; Gelatin, unspecified; Povidone, unspecified; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Butyl alcohol; Tartaric acid; Ammonia; Ferric oxide red; Ferric oxide yellow; Potassium hydroxide; Propylene glycol; Titanium dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a corn
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| Dosage Form | Oral Capsule | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 14 |
DFM Info
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Sodium lauryl sulfate; Butyl alcohol; Isopropyl alcohol; Ammonia; Ferric oxide red; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Alcohol; Gelatin, unspecified; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Merck Sharp & Dohme | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 15 |
DFM Info
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Stearic acid; Anhydrous lactose; Tartaric acid; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Silicon dioxide; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Accord Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 16 |
DFM Info
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Stearic acid; Anhydrous lactose; Tartaric acid; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Gelatin; Sodium starch glycolate type a corn
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| Dosage Form | Oral Capsule | |||||
| Company | Lotus Pharmaceutical; Rising Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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Stearic acid; Anhydrous lactose; Tartaric acid; Ferric oxide red; Titanium dioxide; Silicon dioxide; Gelatin; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Ascend Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 18 |
DFM Info
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Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Gelatin; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Chemi Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Temozolomide 140 mg capsule | Click to Show/Hide the Full List of Formulation(s): 18 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Anhydrous citric acid; Stearic acid; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Mannitol; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Alcohol; Aluminum oxide; Gelatin; Methyl alcohol; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Lannett Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Kyselina citronova | DIG Info | Perilipin-1 (IC50 = 3708 nM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [5] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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Stearic acid; Anhydrous lactose; D&c red no. 28; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Indigotindisulfonate sodium; Tartaric acid; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Aluminum oxide; Fd&c green no. 3; Gelatin; Povidone k29/32; Shellac; Sodium starch glycolate type a potato
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|||||
| Dosage Form | Oral Capsule | |||||
| Company | Avera McKennan Hospital; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Tartaric acid; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Fd&c red no. 3; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type b potato
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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Stearic acid; Anhydrous lactose; D&c red no. 28; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato; Tartaric acid, dl-
|
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| Dosage Form | Oral Capsule | |||||
| Company | Amerigen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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Stearic acid; Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Tartaric acid; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Amneal Pharmaceuticals; AvPAK | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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Methylparaben; Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Propylparaben; Tartaric acid; Titanium dioxide; Water; Silicon dioxide; Gelatin; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | IDT Australia | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [9] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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Stearic acid; Anhydrous lactose; Methylparaben sodium; Propylparaben sodium; Sodium lauryl sulfate; Fd&c blue no. 1; Tartaric acid; Titanium dioxide; Water; Silicon dioxide; Gelatin, unspecified; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Mayne Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium methylparaben | DIG Info | Estrogen receptor beta (EC50 = 1860 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propylparaben sodium | DIG Info | Estrogen receptor alpha (EC50 = 38200 nM) | [10] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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Stearic acid; Anhydrous lactose; Butyl alcohol; Fd&c blue no. 2; Isopropyl alcohol; Tartaric acid; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Lannett Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 2; Tartaric acid; Ammonia; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Propylene glycol; Titanium dioxide; Alcohol; Gelatin, unspecified; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 11 |
DFM Info
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Anhydrous lactose; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Tartaric acid; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Isobutyl alcohol; Titanium dioxide; Silicon dioxide; Alcohol; Gelatin; Polyethylene glycols; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Roxane Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 12 |
DFM Info
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Butyl alcohol; Fd&c blue no. 1; Tartaric acid; Ammonia; Propylene glycol; Titanium dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a corn
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| Dosage Form | Oral Capsule | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Sodium lauryl sulfate; Butyl alcohol; Fd&c blue no. 2; Isopropyl alcohol; Ammonia; Ferric oxide red; Potassium hydroxide; Propylene glycol; Water; Alcohol; Gelatin, unspecified; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Merck Sharp & Dohme | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 14 |
DFM Info
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Stearic acid; Anhydrous lactose; Fd&c blue no. 2; Tartaric acid; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Silicon dioxide; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Accord Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 15 |
DFM Info
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Stearic acid; Anhydrous lactose; Fd&c blue no. 2; Tartaric acid; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Gelatin; Sodium starch glycolate type a corn
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| Dosage Form | Oral Capsule | |||||
| Company | Rising Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 16 |
DFM Info
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Stearic acid; Anhydrous lactose; Fd&c blue no. 2; Tartaric acid; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Gelatin; Sodium starch glycolate type a corn
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| Dosage Form | Oral Capsule | |||||
| Company | Lotus Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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Stearic acid; Anhydrous lactose; Fd&c blue no. 2; Tartaric acid; Titanium dioxide; Silicon dioxide; Gelatin; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Ascend Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 18 |
DFM Info
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Fd&c blue no. 2; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Gelatin; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Chemi Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Temozolomide 180 mg capsule | Click to Show/Hide the Full List of Formulation(s): 18 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Anhydrous citric acid; Stearic acid; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Mannitol; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Alcohol; Aluminum oxide; Gelatin; Methyl alcohol; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Lannett Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Kyselina citronova | DIG Info | Perilipin-1 (IC50 = 3708 nM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [5] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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Stearic acid; Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Indigotindisulfonate sodium; Tartaric acid; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Aluminum oxide; Gelatin; Povidone k29/32; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato; Tartaric acid, dl-
|
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| Dosage Form | Oral Capsule | |||||
| Company | Amerigen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Tartaric acid; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
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|||||
| Dosage Form | Oral Capsule | |||||
| Company | Amneal Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Methylparaben; Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 1; Fd&c yellow no. 6; Propylparaben; Tartaric acid; Titanium dioxide; Water; Silicon dioxide; Gelatin; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | IDT Australia | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [9] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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Stearic acid; Anhydrous lactose; Methylparaben sodium; Propylparaben sodium; Sodium lauryl sulfate; Fd&c blue no. 1; Fd&c yellow no. 6; Tartaric acid; Titanium dioxide; Water; Silicon dioxide; Gelatin, unspecified; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Capsule | |||||
| Company | Mayne Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium methylparaben | DIG Info | Estrogen receptor beta (EC50 = 1860 nM) | [10] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propylparaben sodium | DIG Info | Estrogen receptor alpha (EC50 = 38200 nM) | [10] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Butyl alcohol; Isopropyl alcohol; Tartaric acid; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type b potato
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| Dosage Form | Oral Capsule | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Butyl alcohol; Isopropyl alcohol; Tartaric acid; Ammonia; Ferric oxide red; Ferric oxide yellow; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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Anhydrous lactose; Fd&c red no. 40; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Tartaric acid; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Isobutyl alcohol; Titanium dioxide; Silicon dioxide; Alcohol; Gelatin; Polyethylene glycols; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Roxane Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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Stearic acid; Anhydrous lactose; Butyl alcohol; Isopropyl alcohol; Tartaric acid; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Lannett Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Tartaric acid; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 12 |
DFM Info
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Sodium lauryl sulfate; Butyl alcohol; D&c red no. 7; Fd&c yellow no. 6; Isopropyl alcohol; Ammonia; Propylene glycol; Titanium dioxide; Alcohol; Gelatin, unspecified; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Sodium lauryl sulfate; Butyl alcohol; Isopropyl alcohol; Ammonia; Ferric oxide red; Ferric oxide yellow; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Alcohol; Gelatin, unspecified; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Merck Sharp & Dohme | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 14 |
DFM Info
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Butyl alcohol; Tartaric acid; Ammonia; Ferric oxide red; Propylene glycol; Titanium dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a corn
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| Dosage Form | Oral Capsule | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 15 |
DFM Info
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Stearic acid; Anhydrous lactose; Tartaric acid; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Silicon dioxide; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Accord Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 16 |
DFM Info
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Stearic acid; Anhydrous lactose; Tartaric acid; Ferric oxide red; Titanium dioxide; Silicon dioxide; Gelatin; Sodium starch glycolate type a corn
|
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| Dosage Form | Oral Capsule | |||||
| Company | Lotus Pharmaceutical; Rising Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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Stearic acid; Anhydrous lactose; Tartaric acid; Ferric oxide red; Titanium dioxide; Silicon dioxide; Gelatin; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Capsule | |||||
| Company | Ascend Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 18 |
DFM Info
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Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Gelatin; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Chemi Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Temozolomide 250 mg capsule | Click to Show/Hide the Full List of Formulation(s): 18 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Anhydrous citric acid; Stearic acid; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Mannitol; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Alcohol; Aluminum oxide; Gelatin; Methyl alcohol; Shellac
|
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| Dosage Form | Oral Capsule | |||||
| Company | Lannett Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Kyselina citronova | DIG Info | Perilipin-1 (IC50 = 3708 nM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [5] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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Stearic acid; Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Indigotindisulfonate sodium; Tartaric acid; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Aluminum oxide; Gelatin; Povidone k29/32; Shellac; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Capsule | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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Stearic acid; Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Tartaric acid; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Amneal Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Butyl alcohol; Isopropyl alcohol; Tartaric acid; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type b potato
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Butyl alcohol; Isopropyl alcohol; Tartaric acid; Ammonia; Ferric oxide red; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Methylparaben; Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Propylparaben; Tartaric acid; Ferrosoferric oxide; Titanium dioxide; Water; Silicon dioxide; Gelatin; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Capsule | |||||
| Company | IDT Australia | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [9] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Methylparaben sodium; Propylparaben sodium; Sodium lauryl sulfate; Tartaric acid; Ferrosoferric oxide; Titanium dioxide; Water; Silicon dioxide; Gelatin, unspecified; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Capsule | |||||
| Company | Mayne Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium methylparaben | DIG Info | Estrogen receptor beta (EC50 = 1860 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propylparaben sodium | DIG Info | Estrogen receptor alpha (EC50 = 38200 nM) | [10] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Butyl alcohol; Isopropyl alcohol; Tartaric acid; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Capsule | |||||
| Company | Lannett Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Butyl alcohol; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a potato; Tartaric acid, dl-
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| Dosage Form | Oral Capsule | |||||
| Company | Amerigen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Tartaric acid; Ammonia; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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Sodium lauryl sulfate; Butyl alcohol; Isopropyl alcohol; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Alcohol; Brown iron oxide; Gelatin, unspecified; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Butyl alcohol; Tartaric acid; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Alcohol; Gelatin; Shellac; Sodium starch glycolate type a corn
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| Dosage Form | Oral Capsule | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Sodium lauryl sulfate; Butyl alcohol; Isopropyl alcohol; Ammonia; Ferric oxide red; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Alcohol; Gelatin, unspecified; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Merck Sharp & Dohme | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Sodium lauryl sulfate; Tartaric acid; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Silicon dioxide; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Accord Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Tartaric acid; Titanium dioxide; Silicon dioxide; Gelatin; Sodium starch glycolate type a corn
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| Dosage Form | Oral Capsule | |||||
| Company | Lotus Pharmaceutical; Rising Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Tartaric acid; Titanium dioxide; Silicon dioxide; Gelatin; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Ascend Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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|
|||||
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Anhydrous lactose; Magnesium stearate; Tartaric acid; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Isobutyl alcohol; Titanium dioxide; Silicon dioxide; Alcohol; Gelatin; Polyethylene glycols; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Roxane Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 18 |
DFM Info
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Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Water; Gelatin; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Chemi Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
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