Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00103) | |||||
|---|---|---|---|---|---|
| Name |
Carvedilol
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| Synonyms |
Click to Show/Hide the Synonyms of This API
carvedilol; 72956-09-3; Dilatrend; Eucardic; Carvedilolum [Latin]; BM 14190; Carvedilolum; 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol; BM-14190; SKF 105517; 1-((9H-Carbazol-4-yl)oxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)propan-2-ol; DQ 2466; 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol; C24H26N2O4; (+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol; CHEMBL723; DQ-2466; CHEBI:3441; 1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol; MFCD00864692; (R)-BM 14190; (S)-BM 14190; Kredex; Querto; BM 14.190; Coropress; Artist; Dibloc; [3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-methoxyphenoxy)ethyl]amine; 1-(9H-carbazol-4-yloxy)-3-[(2-{[2-(methyloxy)phenyl]oxy}ethyl)amino]propan-2-ol; SMR000449280; Artist (TN); Coreg (TN); HSDB 7044; SR-01000759289; MFCD00869663; C07AG02; EG-P042; Carvedilol [USAN:USP:INN:BAN:JAN]; SK&F-105517; PubChem18218; Spectrum_001665; BM-14-190; BM-14.190; Spectrum2_001673; Spectrum3_001182; Spectrum4_000636; Spectrum5_001436; SCHEMBL22293; GTPL551; KBioGR_001252; KBioSS_002145; MLS000758299; MLS000759508; MLS001424092; MLS006011886; SPBio_001885; Carvedilol (JP17/USP/INN); DTXSID8022747; SCHEMBL10082334; SCHEMBL13287211; BDBM25759; KBio2_002145; KBio2_004713; KBio2_007281; KBio3_002323; HMS2051N03; HMS2089B09; HMS2093E12; HMS3261E15; HMS3269N11; HMS3393N03; HMS3413B14; HMS3655O14; HMS3677B14; HMS3715D15; HMS3750I15; HMS3884E12; Pharmakon1600-01504257; Carvedilol 1.0 mg/ml in Methanol; BCP23386; HY-B0006; Tox21_500347; BBL029064; NSC758694; STK621453; AKOS005554967; Carvedilol, >=98% (HPLC), solid; AC-1641; BCP9000493; CCG-100917; CCG-207952; CS-1194; DB01136; KS-1037; LP00347; MCULE-7944987271; NC00167; NSC-758694; SB17441; SDCCGSBI-0206771.P002; SKF-105517; 2-Propanol, 1-(9H-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)-, (+-)-; NCGC00167832-01; NCGC00167832-02; NCGC00167832-03; NCGC00167832-04; NCGC00167832-19; NCGC00261032-01; SY129821; BCP0726000253; SBI-0206771.P001; AB0008431; DB-055704; DB-057556; DB-057557; FT-0603055; FT-0603057; FT-0652640; FT-0664397; SW197547-3; C06875; D00255; J10039; W-5131; AB00639903-07; AB00639903-09; AB00639903_10; AB00639903_11; AB00639903_12; 102641-EP2270011A1; 102641-EP2272841A1; 102641-EP2275420A1; 102641-EP2298764A1; 102641-EP2298765A1; 102641-EP2301936A1; 956C093; L001243; Q412534; Q-200801; SR-01000759289-5; SR-01000759289-6; SR-01000759289-9; BRD-A10977446-001-04-8; BRD-A10977446-001-05-5; BRD-A10977446-045-01-1; Z2786051695; Carvedilol, European Pharmacopoeia (EP) Reference Standard; Ethyl 2-(9-(pyridin-4-ylmethyl)-9H-fluoren-9-yl)acetate; Carvedilol, United States Pharmacopeia (USP) Reference Standard; 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxy-phenoxy)-ethylamino]-propan-2-ol; Carvedilol, Pharmaceutical Secondary Standard; Certified Reference Material; (R)-1-[(4-Carbazolyl)oxy]-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol; 107741-96-8
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| Clinical Status |
Approved
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| Disease Indication | Congestive heart failure | ICD-11: BD10 | [1] | ||
| PubChem CID | |||||
| Formula |
C24H26N2O4
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| Canonical SMILES |
COC1=CC=CC=C1OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O
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| InChI |
1S/C24H26N2O4/c1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20/h2-12,17,25-27H,13-16H2,1H3
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| InChIKey |
OGHNVEJMJSYVRP-UHFFFAOYSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=2585"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 406.5 | Topological Polar Surface Area | 75.7 | |
| XlogP | 4.2 | Complexity | 508 | ||
| Heavy Atom Count | 30 | Rotatable Bond Count | 10 | ||
| Hydrogen Bond Donor Count | 3 | Hydrogen Bond Acceptor Count | 5 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
|---|---|---|---|---|---|---|
| Carvedilol 40 mg capsule | Click to Show/Hide the Full List of Formulation(s): 6 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Crospovidone; Povidone; Cellulose, microcrystalline; Hydrogenated castor oil
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 3 |
DFM Info
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Magnesium stearate; Crospovidone; Cellulose, microcrystalline; Hydrogenated castor oil; Povidones
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Carilion Materials Management | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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|
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Magnesium stearate; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hydrogenated castor oil; Povidones
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 5 |
DFM Info
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|
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Magnesium stearate; Crospovidone (15 mpa.s at 5%); Hydrogenated castor oil; Microcrystalline cellulose; Povidone, unspecified
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 6 |
DFM Info
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|
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Magnesium stearate; Crospovidone, unspecified; Hydrogenated castor oil; Microcrystalline cellulose; Povidone, unspecified
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carvedilol 10 mg capsule | Click to Show/Hide the Full List of Formulation(s): 6 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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|
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Crospovidone; Povidone; Cellulose, microcrystalline; Hydrogenated castor oil
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 3 |
DFM Info
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|
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Magnesium stearate; Crospovidone; Cellulose, microcrystalline; Hydrogenated castor oil; Povidones
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Carilion Materials Management | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hydrogenated castor oil; Povidones
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 5 |
DFM Info
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|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Crospovidone (15 mpa.s at 5%); Hydrogenated castor oil; Microcrystalline cellulose; Povidone, unspecified
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 6 |
DFM Info
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|
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Crospovidone, unspecified; Hydrogenated castor oil; Microcrystalline cellulose; Povidone, unspecified
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carvedilol 80 mg capsule | Click to Show/Hide the Full List of Formulation(s): 6 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|
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Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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|
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Crospovidone; Povidone; Cellulose, microcrystalline; Hydrogenated castor oil
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 3 |
DFM Info
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|
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Magnesium stearate; Crospovidone; Cellulose, microcrystalline; Hydrogenated castor oil; Povidones
|
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Carilion Materials Management | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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|
|||||
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Magnesium stearate; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hydrogenated castor oil; Povidones
|
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Magnesium stearate; Crospovidone (15 mpa.s at 5%); Hydrogenated castor oil; Microcrystalline cellulose; Povidone, unspecified
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 6 |
DFM Info
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|
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Magnesium stearate; Crospovidone, unspecified; Hydrogenated castor oil; Microcrystalline cellulose; Povidone, unspecified
|
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carvedilol 12.5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 40 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Magnesium stearate; Mannitol; Sucrose; Talc; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone; Silicon dioxide; Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | AvKARE; Caraco Pharmaceutical Laboratories; Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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Lactose monohydrate; Sodium citrate; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium citrate anhydrous | DIG Info | Carbonic anhydrase IV (Ki = 99 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Sodium citrate; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Bayshore Pharmaceuticals; Cardinal Health; RemedyRepack; Solco Healthcare; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium citrate anhydrous | DIG Info | Carbonic anhydrase IV (Ki = 99 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose monohydrate; Sodium citrate; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium citrate anhydrous | DIG Info | Carbonic anhydrase IV (Ki = 99 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Lactose monohydrate; Sodium citrate, unspecified form; Magnesium stearate; Sucrose; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Clinical Solutions Wholesale | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium citrate anhydrous | DIG Info | Carbonic anhydrase IV (Ki = 99 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Titanium dioxide; Crospovidone; Hypromellose; Polysorbate 80; Povidone; Silicon dioxide; Polyethylene glycol
|
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromellose 2910 (5 mpa.s)
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromellose 2910 (5 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Aidarex Pharmaceuticals; Aphena Pharma Solutions-Tennessee; Aurobindo Pharma; Aurolife Pharma; Blenheim Phamacal; Bryant Ranch Prepack; Lucid Pharma; NCS HealthCare of KY, Inc dba Vangard Labs; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; Physicians Total Care; Proficient Rx; RemedyRepack; St Marys Medical Park Pharmacy; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 12 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hydroxypropyl methylcellulose e5 [ii]
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 13 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (5 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Avera McKennan Hospital; MedVantx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 14 |
DFM Info
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Lactose; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Polysorbate 80; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 16 |
DFM Info
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Lactose; Magnesium stearate; Titanium dioxide; Crospovidone; Polysorbate 80; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Titanium dioxide; Crospovidone; Polysorbate 80; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Titanium dioxide; Crospovidone; Polysorbate 80; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | H. J. Harkins Company; RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Sucrose; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Bryant Ranch Prepack; Preferred Pharamaceuticals; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Polysorbate 80; Povidone; Colloidal silicon dioxide; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Hikma Pharmaceutical; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Colloidal silicon dioxide; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Legacy Pharmaceutical; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromelloses; Povidone k12
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Colloidal silicon dioxide; Hydroxypropyl methylcellulose e5 [ii]; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Colloidal silicon dioxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Hypromellose; Povidone; Colloidal silicon dioxide; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Titanium dioxide; Crospovidone; Polysorbate 80; Silicon dioxide; Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; Glenmark Pharmaceutials; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Povidone; Colloidal silicon dioxide; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging; Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Sucrose; Titanium dioxide; Polysorbate 80; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols; Povidones
|
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| Dosage Form | Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 35 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Titanium dioxide; Polysorbate 80; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Clinical Solutions Wholesale | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 36 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Crospovidone, unspecified; Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
|
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| Dosage Form | Oral Tablet | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | BluePoint Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 38 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
|
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 39 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 6000; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Cipla | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Drug Formulation 40 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxyethyl cellulose (140 mpa.s at 5%); Polyethylene glycol 800
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Carvedilol 25 mg tablet | Click to Show/Hide the Full List of Formulation(s): 35 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Sucrose; Talc; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone; Silicon dioxide; Hypromellose 2910 (6 mpa.s)
|
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| Dosage Form | Oral Tablet | |||||
| Company | AvKARE; Caraco Pharmaceutical Laboratories; Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; Sodium citrate; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium citrate anhydrous | DIG Info | Carbonic anhydrase IV (Ki = 99 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Sodium citrate; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bayshore Pharmaceuticals; Cardinal Health; DirectRX; RemedyRepack; Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium citrate anhydrous | DIG Info | Carbonic anhydrase IV (Ki = 99 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose monohydrate; Sodium citrate, unspecified form; Magnesium stearate; Sucrose; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Clinical Solutions Wholesale | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium citrate anhydrous | DIG Info | Carbonic anhydrase IV (Ki = 99 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Titanium dioxide; Crospovidone; Hypromellose; Polysorbate 80; Povidone; Silicon dioxide; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Aurobindo Pharma; Aurolife Pharma; Blenheim Phamacal; Bryant Ranch Prepack; Legacy Pharmaceutical; Lucid Pharma; NCS HealthCare of KY, Inc dba Vangard Labs; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; Physicians Total Care; Proficient Rx; RemedyRepack; St Marys Medical Park Pharmacy; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Legacy Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Polysorbate 80; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Titanium dioxide; Crospovidone; Polysorbate 80; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 15 |
DFM Info
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Sucrose 1,6-distearate; Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromellose 2910 (5 mpa.s); Polyethylene glycol 4000000
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Sucrose; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Preferred Pharamaceuticals; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Polysorbate 80; Povidone; Colloidal silicon dioxide; Hypromelloses; Polyethylene glycol
|
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| Dosage Form | Oral Tablet | |||||
| Company | Hikma Pharmaceutical; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Colloidal silicon dioxide; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Legacy Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (5 mpa.s)
|
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromelloses; Povidone k12
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Colloidal silicon dioxide; Hydroxypropyl methylcellulose e5 [ii]; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Titanium dioxide; Crospovidone; Polysorbate 80; Silicon dioxide; Hypromelloses; Polyethylene glycols; Povidones
|
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Aidarex Pharmaceuticals; Cardinal Health; Glenmark Pharmaceutials; Proficient Rx; RemedyRepack; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Polysorbate 80; Silicon dioxide; Hypromelloses; Polyethylene glycols; Povidone k12
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Povidone; Colloidal silicon dioxide; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging; Legacy Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Sucrose; Titanium dioxide; Polysorbate 80; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Titanium dioxide; Polysorbate 80; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Clinical Solutions Wholesale | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Crospovidone, unspecified; Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
|
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | BluePoint Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 6000; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cipla | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Drug Formulation 35 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxyethyl cellulose (140 mpa.s at 5%); Polyethylene glycol 800
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Carvedilol 3.125 mg tablet | Click to Show/Hide the Full List of Formulation(s): 39 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Sucrose; Talc; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone; Silicon dioxide; Hypromellose 2910 (6 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | AvKARE; Caraco Pharmaceutical Laboratories; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Sucrose; Talc; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Hypromellose 2910 (6 mpa.s); Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 6 |
DFM Info
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Lactose monohydrate; Sodium citrate; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Avera McKennan Hospital; Bayshore Pharmaceuticals; Cardinal Health; Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium citrate anhydrous | DIG Info | Carbonic anhydrase IV (Ki = 99 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose monohydrate; Sodium citrate, unspecified form; Magnesium stearate; Sucrose; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Clinical Solutions Wholesale | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium citrate anhydrous | DIG Info | Carbonic anhydrase IV (Ki = 99 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Titanium dioxide; Crospovidone; Hypromellose; Polysorbate 80; Povidone; Silicon dioxide; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Aidarex Pharmaceuticals; Aphena Pharma Solutions-Tennessee; Aurobindo Pharma; Aurolife Pharma; Blenheim Phamacal; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Lucid Pharma; NCS HealthCare of KY, Inc dba Vangard Labs; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; Physicians Total Care; Rebel Distributors; RemedyRepack; St Marys Medical Park Pharmacy; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | MedVantx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Polysorbate 80; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Titanium dioxide; Crospovidone; Polysorbate 80; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 15 |
DFM Info
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Sucrose 1,6-distearate; Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromellose 2910 (5 mpa.s); Polyethylene glycol 4000000
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Sucrose; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Polysorbate 80; Povidone; Colloidal silicon dioxide; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Hikma Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Colloidal silicon dioxide; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromelloses; Povidone k12
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Polysorbate 80; Povidone; Colloidal silicon dioxide; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Titanium dioxide; Crospovidone; Polysorbate 80; Silicon dioxide; Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Cardinal Health; Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Titanium dioxide; Crospovidone; Polysorbate 80; Silicon dioxide; Hypromelloses; Polyethylene glycol, unspecified; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Povidone; Colloidal silicon dioxide; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; American Health Packaging; Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Sucrose; Titanium dioxide; Polysorbate 80; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Aminolevulinic acid hydrochloride; Aminometradine; Aminopentamide sulfate; Aminophylline; Aminopromazine; Aminopropazine fumarate; Aminopterin sodium; Ammi visnaga fruit; Amoproxan; Hypromelloses; Polyethylene glycols; Povidones
|
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| Dosage Form | Oral Tablet | |||||
| Company | Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Titanium dioxide; Polysorbate 80; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Clinical Solutions Wholesale | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Titanium dioxide; Polysorbate 80; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Beta.-d-galactose; Magnesium stearate; Crospovidone; Polysorbate 80; Ammonium laureth-5 sulfate; Copovidone; Hydrated silica; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 35 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Crospovidone, unspecified; Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 36 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | BluePoint Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 38 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 6000; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Cipla | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Drug Formulation 39 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxyethyl cellulose (140 mpa.s at 5%); Polyethylene glycol 800
|
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Carvedilol 6.25 mg tablet | Click to Show/Hide the Full List of Formulation(s): 37 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Sucrose; Talc; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone; Silicon dioxide; Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | AvKARE; Caraco Pharmaceutical Laboratories; Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; Sodium citrate; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Avera McKennan Hospital; Bayshore Pharmaceuticals; Cardinal Health; Solco Healthcare; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium citrate anhydrous | DIG Info | Carbonic anhydrase IV (Ki = 99 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Sodium citrate, unspecified form; Magnesium stearate; Sucrose; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Clinical Solutions Wholesale | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium citrate anhydrous | DIG Info | Carbonic anhydrase IV (Ki = 99 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Titanium dioxide; Crospovidone; Hypromellose; Polysorbate 80; Povidone; Silicon dioxide; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromellose 2910 (5 mpa.s)
|
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Aurobindo Pharma; Aurolife Pharma; Blenheim Phamacal; Bryant Ranch Prepack; Lucid Pharma; NCS HealthCare of KY, Inc dba Vangard Labs; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; Physicians Total Care; RemedyRepack; St Marys Medical Park Pharmacy; State of Florida DOH Central Pharmacy; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone; Colloidal silicon dioxide; Hypromellose 2910 (5 mpa.s)
|
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| Dosage Form | Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Titanium dioxide; Crospovidone; Polysorbate 80; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Sucrose; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; DirectRX; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Polysorbate 80; Povidone; Colloidal silicon dioxide; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Hikma Pharmaceutical; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 17 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Colloidal silicon dioxide; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Legacy Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (5 mpa.s)
|
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 21 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromelloses; Povidone k12
|
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Colloidal silicon dioxide; Hydroxypropyl methylcellulose e5 [ii]; Povidones
|
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Povidone; Silicon dioxide; Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Titanium dioxide; Crospovidone; Polysorbate 80; Silicon dioxide; Hypromelloses; Polyethylene glycols; Povidones
|
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Aidarex Pharmaceuticals; Avera McKennan Hospital; Cardinal Health; Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Povidone; Colloidal silicon dioxide; Hypromelloses; Polyethylene glycol
|
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| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Hypromelloses; Polyethylene glycols; Povidones
|
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Sucrose; Titanium dioxide; Polysorbate 80; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols; Povidones
|
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| Dosage Form | Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Aminolevulinic acid hydrochloride; Aminometradine; Aminopentamide sulfate; Aminophylline; Aminopromazine; Aminopropazine fumarate; Aminopterin sodium; Ammi visnaga fruit; Amoproxan; Hypromelloses; Polyethylene glycols; Povidones
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| Dosage Form | Oral Tablet | |||||
| Company | Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Crospovidone; Polysorbate 80; Colloidal silicon dioxide; Hypromellose 2910 (5 mpa.s); Polyethylene glycol 4000000; Povidone k12
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Crospovidone; Povidone; Colloidal silicon dioxide; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | H. J. Harkins Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Titanium dioxide; Polysorbate 80; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols; Povidones
|
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| Dosage Form | Oral Tablet | |||||
| Company | Clinical Solutions Wholesale | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | BluePoint Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
|
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 35 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 36 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 6000; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cipla | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxyethyl cellulose (140 mpa.s at 5%); Polyethylene glycol 800
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Carvedilol 20 mg capsule | Click to Show/Hide the Full List of Formulation(s): 6 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 1; Fd&c yellow no. 5; Fd&c yellow no. 6; Magnesium stearate; Ammonia; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Dimethicone 410; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Magnesium stearate; Crospovidone; Povidone; Cellulose, microcrystalline; Hydrogenated castor oil
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Magnesium stearate; Crospovidone; Cellulose, microcrystalline; Hydrogenated castor oil; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Carilion Materials Management | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Magnesium stearate; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hydrogenated castor oil; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Magnesium stearate; Crospovidone (15 mpa.s at 5%); Hydrogenated castor oil; Microcrystalline cellulose; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Magnesium stearate; Crospovidone, unspecified; Hydrogenated castor oil; Microcrystalline cellulose; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
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