Details of the Active Pharmaceutical Ingredient (API)

General Information of API (ID: D00088)
Name
Caffeine
Synonyms    Click to Show/Hide the Synonyms of This API
caffeine; 1,3,7-Trimethylxanthine; Guaranine; Methyltheobromine; Cafeina; Theine; Koffein; Mateina; Alert-pep; Caffein; Cafipel; Coffeine; Refresh'n; Caffedrine; Cafamil; Cafecon; Caffine; Dexitac; Nodaca; Anhydrous caffeine; No-Doz; Eldiatric C; 7-Methyltheophylline; Hycomine; Organex; Vivarin; Nix Nap; Methyltheobromide; 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione; Coffein; Phensal; Caffeine, synthetic; 1,3,7-Trimethylpurine-2,6-dione; Quick-Pep; Coffeinum; Tirend; 1,3,7-Trimethyl-2,6-dioxopurine; Theophylline, 7-methyl; DHCplus; Tri-Aqua; 1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-; Kofein; Miudol; Caffeine, anhydrous; Theobromine, 1-methyl-; Propoxyphene Compound 65; 1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione; Kofein [Czech]; Coffein [German]; Koffein [German]; 1-methyltheobromine; Caffeine (natural); Xanthine, 1,3,7-trimethyl; Caffeina [Italian]; Theophylline Me; Methylxanthine theophylline; Theobromine Me; NCI-C02733; SK-65 Compound; Anacin; Anacin Maximum Strength; P-A-C Analgesic Tablets; C8H10N4O2; HSDB 36; FEMA No. 2224; BRN 0017705; 1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione; NSC 5036; A.S.A. and Codeine Compound; UNII-3G6A5W338E; 1,3,7-trimethyl-1H-purine-2,6(3H,7H)-dione; AI3-20154; MFCD00005758; CHEMBL113; CHEBI:27732; 3G6A5W338E; NSC-5036; caffenium; SK 65 Compound; Caffeina; DSSTox_CID_232; Caffeine [BAN:JAN]; CAFFEINE-D3; DSSTox_RID_75448; DSSTox_GSID_20232; 1,3,7-trimethyl-1,3,7-trihydropurine-2,6-dione; cafeine; peyona; CAS-58-08-2; Caffeine (USP); SMR000326667; CCRIS 1314; SR-01000075187; Anhydrous caffeine (TN); EINECS 200-362-1; Monomethyl derivative of Theophylline; Caffeine [USP:BAN:JAN]; Anhydrous caffeine (JP15); Caffeine, 98.5%, specified according to the req. of USP/BP; Caffeine hydrous; Caffeine, BioXtra; TNP00310; Monohydrate Caffeine; Respia (TN); 1-methyl-Theobromine; 7-methyl Theophylline; PubChem9436; Cafergot (Salt/Mix); 1,7-Trimethylxanthine; Spectrum_001301; 3,7-dihydro-1,3,7-trimethyl-1H-purine; Xanthine,3,7-trimethyl; Theine, methyltheobromine; Spectrum2_001261; Spectrum3_000321; Spectrum4_001782; Spectrum5_000423; Lopac-C-0750; bmse000206; MolMap_000054; Probes1_000150; Probes2_000128; C 0750; EC 200-362-1; SCHEMBL5671; Anhydrous caffeine (JP17); NCIOpen2_008255; BIDD:PXR0172; Lopac0_000228; 1, 3, 7-Trimethylxanthine; BSPBio_001921; GTPL407; KBioGR_002325; KBioSS_001781; 5-26-13-00558 (Beilstein Handbook Reference); MLS001055341; MLS001056714; MLS001066409; ARONIS25359; BIDD:ER0554; BIDD:GT0632; Caffeine, 1mg/ml in methanol; DivK1c_000730; SPECTRUM1500155; CU-01000012617-3; SPBio_001222; Caffeine melting point standard; MEGxp0_001350; ZINC1084; 1,3,7-trimethyl-2,6-dioxo-1,2,3,6-tetrahydropurine; component of Dilone (Salt/Mix); DTXSID0020232; 1,7-Trimethyl-2,6-dioxopurine; ACon1_000085; BDBM10849; HMS502E12; KBio1_000730; KBio2_001781; KBio2_004349; KBio2_006917; KBio3_001141; Caffeine 1.0 mg/ml in Methanol; NSC5036; Caffeine, powder, ReagentPlus(R); component of Percodan (Salt/Mix); NINDS_000730; Bio1_000473; Bio1_000962; Bio1_001451; HMS1920I09; HMS2091O11; HMS2232M13; HMS3260N17; HMS3372J18; HMS3435F10; HMS3715D13; Pharmakon1600-01500155; NoDoz Caplets and Chewable Tablets; Caffeine 10 microg/mL in Methanol; CS-M0795; Tox21_201685; Tox21_300010; Tox21_500228; BBL016491; caffeine (1,3,7-trimethylxanthine); Caffeine 100 microg/mL in Methanol; CCG-38825; NSC755917; PDSP1_001016; PDSP1_001235; PDSP2_001000; PDSP2_001219; SBB006474; STK177283; Propoxyphene Compound 65 (Salt/Mix); AKOS000121334; 5-26-13-00558 (Beilstein); ACN-034787; Bayer Select Headache Pain (Salt/Mix); Caffeine, anhydrous, 99%, FCC, FG; DB00201; LP00228; MCULE-3362813910; NSC-755917; SDCCGMLS-0064595.P001; SDCCGMLS-0064595.P002; SDCCGSBI-0050216.P005; IDI1_000730; 3,3,7-trimethyl-1H-purine-2,6-dione; NCGC00015208-01; NCGC00015208-02; NCGC00015208-03; NCGC00015208-04; NCGC00015208-05; NCGC00015208-06; NCGC00015208-07; NCGC00015208-08; NCGC00015208-10; NCGC00015208-11; NCGC00015208-12; NCGC00015208-13; NCGC00015208-14; NCGC00015208-15; NCGC00015208-16; NCGC00015208-17; NCGC00015208-18; NCGC00015208-20; NCGC00015208-29; NCGC00090699-01; NCGC00090699-02; NCGC00090699-03; NCGC00090699-04; NCGC00090699-05; NCGC00090699-06; NCGC00090699-07; NCGC00090699-08; NCGC00090699-09; NCGC00168808-01; NCGC00168808-02; NCGC00254057-01; NCGC00259234-01; NCGC00260913-01; AC-12774; AS-15340; Caffeine, SAJ special grade, >=98.5%; component of P-A-C Compound (Salt/Mix); ST057528; component of A.S.A. Compound (Salt/Mix); SBI-0050216.P004; DB-023002; WLN: T56 BN DN FNVNVJ B1 F1 H1; EU-0100228; FT-0664195; 3378-EP2269610A2; 3378-EP2275420A1; 3378-EP2277848A1; 3378-EP2277867A2; 3378-EP2280003A2; 3378-EP2284160A1; 3378-EP2289510A1; 3378-EP2295409A1; 3378-EP2295434A2; 3378-EP2301937A1; 3378-EP2305219A1; 3378-EP2305662A1; 3378-EP2305671A1; 3378-EP2305677A1; 3378-EP2305682A1; 3378-EP2305695A2; 3378-EP2305696A2; 3378-EP2305697A2; 3378-EP2305698A2; 3378-EP2308562A2; 3378-EP2308840A1; 3378-EP2308867A2; 3378-EP2308870A2; 3378-EP2308879A1; 3378-EP2311801A1; 3378-EP2311802A1; 3378-EP2311803A1; 3378-EP2311806A2; 3378-EP2311808A1; 3378-EP2311829A1; 3378-EP2311842A2; 3378-EP2314588A1; 3378-EP2314590A1; 3378-EP2314593A1; 3378-EP2316457A1; 3378-EP2316458A1; 3378-EP2316825A1; 3378-EP2316826A1; 3378-EP2316827A1; 3378-EP2316828A1; 3378-EP2371814A1; BIM-0050216.0001; C07481; D00528; Q60235; 1,3,7-trimethyl-3,7-dihydropurine-2,6-dione; 1H-Purine-2, 3,7-dihydro-1,3,7-trimethyl-; AB00051930-09; AB00051930_10; Caffeine, purum, anhydrous, >=99.0% (HPLC); 3,7-dihydro-1,3,7-trimethyl-1H-purine (9CI); Caffeine, anhydrous, tested according to Ph.Eur.; L000155; 3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion; Caffeine, Sigma Reference Standard, vial of 250 mg; SR-01000075187-1; SR-01000075187-4; SR-01000075187-7; SR-01000075187-8; BRD-K02404261-001-02-7; BRD-K02404261-001-03-5; BRD-K02404261-001-07-6; Caffeine, certified reference material, TraceCERT(R); Caffeine, meets USP testing specifications, anhydrous; Melting point standard 235-237C, analytical standard; 1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione #; Caffeine, British Pharmacopoeia (BP) Reference Standard; Caffeine, European Pharmacopoeia (EP) Reference Standard; F3371-0262; Z112207564; Caffeine 2000 microg/mL in Water:Methanol (81:19 g/g); 07E4FB58-FD79-4175-8E3D-05BF96954522; 3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion (coffein); Caffeine solution, analytical standard, 1.0 mg/mL in methanol; Caffeine, United States Pharmacopeia (USP) Reference Standard; Caffeine, Pharmaceutical Secondary Standard; Certified Reference Material; Caffeine for system suitability, European Pharmacopoeia (EP) Reference Standard; 114303-55-8
Clinical Status
Approved
Disease Indication Orthostatic hypotension ICD-11: BA21 [1]
PubChem CID
2519
Formula
C8H10N4O2
Canonical SMILES
CN1C=NC2=C1C(=O)N(C(=O)N2C)C
InChI
1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3
InChIKey
RYYVLZVUVIJVGH-UHFFFAOYSA-N
   Click to Show/Hide the Molecular Data (Structure/Property) of This API
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=2519"></iframe>
3D MOL 2D MOL
Physicochemical Properties Molecular Weight 194.19 Topological Polar Surface Area 58.4
XlogP -0.1 Complexity 293
Heavy Atom Count 14 Rotatable Bond Count 0
Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 3
Full List of Drug Formulations (DFMs) Containing This API
          Caffeine 200 mg tablet Click to Show/Hide the Full List of Formulation(s):        56 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Vanillin; Sodium lauryl sulfate; Calcium carbonate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Calcium sulfate dihydrate; Magnesium silicate; Titanium dioxide; Hypromellose; Polysorbate 80; Mineral oil; Polyethylene glycol; Sodium starch glycolate type a potato; Starch, corn
                   Dosage Form Oral Tablet
                   Company Alva-Amco Pharmacal Companies
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Allura red AC dye DIG Info Solute carrier SLCO2B1 (Ki = 4.7 uM) [2]
FD&C blue no. 1 DIG Info Solute carrier SLCO2B1 (Ki = 13 uM) [3]
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [2]
Calcium carbonate DIG Info Carbonic anhydrase IX (Ki = 8600 nM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Vanillin DIG Info Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) [5]
Allura red AC dye DIG Info Solute carrier SLCO2B1 (Ki = 2.59 uM) [3]
Hypromellose DIG Info Cytochrome P450 3A5 (IC50 = 19.4 uM) [6]
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Vanillin; Sodium lauryl sulfate; Calcium carbonate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Calcium sulfate dihydrate; Magnesium silicate; Titanium dioxide; Hypromellose; Polysorbate 80; Mineral oil; Polyethylene glycol 600; Sodium starch glycolate type a potato; Starch, corn
                   Dosage Form Oral Tablet
                   Company Alva-Amco Pharmacal Companies
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Allura red AC dye DIG Info Solute carrier SLCO2B1 (Ki = 4.7 uM) [2]
FD&C blue no. 1 DIG Info Solute carrier SLCO2B1 (Ki = 13 uM) [3]
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [2]
Calcium carbonate DIG Info Carbonic anhydrase IX (Ki = 8600 nM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Vanillin DIG Info Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) [5]
Allura red AC dye DIG Info Solute carrier SLCO2B1 (Ki = 2.59 uM) [3]
Hypromellose DIG Info Cytochrome P450 3A5 (IC50 = 19.4 uM) [6]
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Calcium carbonate; Fd&c red no. 40; Maltodextrin; Taurine; Fd&c yellow no. 6; Magnesium stearate; Magnesium silicate; Titanium dioxide; Triacetin; Hypromellose; Acacia; Cellulose, microcrystalline; Mineral oil; Starch, corn
                   Dosage Form Oral Tablet
                   Company Alva-Amco Pharmacal Companies
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Allura red AC dye DIG Info Solute carrier SLCO2B1 (Ki = 4.7 uM) [2]
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Taurine DIG Info GABA(A) receptor rho-1 (EC50 = 4600 nM) [9]
Calcium carbonate DIG Info Carbonic anhydrase IX (Ki = 8600 nM) [4]
Allura red AC dye DIG Info Solute carrier SLCO2B1 (Ki = 2.59 uM) [3]
Hypromellose DIG Info Cytochrome P450 3A5 (IC50 = 19.4 uM) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Dextrin DIG Info Colon cancer Caco-2 cells (Inhibition ratio > 55 %) [8]
             Drug Formulation 4 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Propylene glycol; Sucrose; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Povidones; Sodium starch glycolate type a corn; Sodium starch glycolate type a potato
                   Dosage Form Oral Tablet
                   Company Lil Drug Store Products
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
FD&C blue no. 1 DIG Info Solute carrier SLCO2B1 (Ki = 13 uM) [3]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [10]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 5 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; D&c red no. 27; Fd&c blue no. 1; Magnesium stearate; Dibasic calcium phosphate dihydrate; Magnesium silicate; Sucrose; Titanium dioxide; Croscarmellose sodium; Povidone; Silicon dioxide; Cellulose, microcrystalline
                   Dosage Form Oral Tablet
                   Company King Richard Promotions dba DBI
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
FD&C blue no. 1 DIG Info Solute carrier SLCO2B1 (Ki = 13 uM) [3]
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
D&C red no. 27 DIG Info Solute carrier SLCO2B1 (Ki = 1 uM) [3]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 6 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Benzoic acid; Stearic acid; Fd&c blue no. 1; Sorbitan monolaurate; Propylene glycol; Sucrose; Titanium dioxide; Polysorbate 20; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Dimethicone; Hypromelloses; Light mineral oil; Povidones; Starch, corn
                   Dosage Form Oral Tablet
                   Company GlaxoSmithKline
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Benzoic acid DIG Info FHA-HIT-interacting protein (Ki = 1.9 nM) [11]
FD&C blue no. 1 DIG Info Solute carrier SLCO2B1 (Ki = 13 uM) [3]
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [10]
Polysorbate 20 DIG Info Cytochrome P450 2E1 (IC50 = 64.1 uM) [6]
Sorbitan monolaurate DIG Info Multidrug resistance protein 1 (Inhibition ratio > 70 %) [12]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 7 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Propylene glycol; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses
                   Dosage Form Oral Tablet
                   Company Chain Drug Consortium
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [10]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 8 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Benzoic acid; Stearic acid; Fd&c blue no. 1; Sorbitan monolaurate; Sucrose; Titanium dioxide; Polyethylene glycol 6000; Polysorbate 20; Carnauba wax; Cellulose, microcrystalline; Dimethicone; Hypromelloses; Light mineral oil; Povidones; Starch, corn
                   Dosage Form Oral Tablet
                   Company Eagle Distributors
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Benzoic acid DIG Info FHA-HIT-interacting protein (Ki = 1.9 nM) [11]
FD&C blue no. 1 DIG Info Solute carrier SLCO2B1 (Ki = 13 uM) [3]
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Polysorbate 20 DIG Info Cytochrome P450 2E1 (IC50 = 64.1 uM) [6]
Sorbitan monolaurate DIG Info Multidrug resistance protein 1 (Inhibition ratio > 70 %) [12]
Polyethylene glycol 6000 DIG Info Albendazole monooxygenase (Inhibition ratio < 70 %) [10]
             Drug Formulation 9 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Benzoic acid; Stearic acid; Fd&c blue no. 1; Sorbitan monolaurate; Propylene glycol; Sucrose; Titanium dioxide; Polysorbate 20; Carnauba wax; Cellulose, microcrystalline; Dimethicone; Hypromelloses; Light mineral oil; Povidones; Starch, corn
                   Dosage Form Oral Tablet
                   Company SOHM
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Benzoic acid DIG Info FHA-HIT-interacting protein (Ki = 1.9 nM) [11]
FD&C blue no. 1 DIG Info Solute carrier SLCO2B1 (Ki = 13 uM) [3]
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [10]
Polysorbate 20 DIG Info Cytochrome P450 2E1 (IC50 = 64.1 uM) [6]
Sorbitan monolaurate DIG Info Multidrug resistance protein 1 (Inhibition ratio > 70 %) [12]
             Drug Formulation 10 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Silicon dioxide; Carnauba wax; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Starch, corn
                   Dosage Form Oral Tablet
                   Company Navajo Manufacturing
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 11 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Maltodextrin; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polyethylene glycol 1000; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Dextrates; Hypromelloses
                   Dosage Form Oral Tablet
                   Company We Care Distributor
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Polyethylene glycol 1000 DIG Info Cytochrome P450 2E1 (IC50 = 75.3 uM) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Dextrin DIG Info Colon cancer Caco-2 cells (Inhibition ratio > 55 %) [8]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 12 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Silicon dioxide; Hypromelloses; Microcrystalline cellulose
                   Dosage Form Oral Tablet
                   Company Marc Glassman, Inc.
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Polyethylene glycol 400 DIG Info Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) [10]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 13 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polysorbate 80; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Dextrose; Hypromelloses; Polyethylene glycols; Starch, corn
                   Dosage Form Oral Tablet
                   Company Meda Consumer Healthcare
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 14 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Hypromelloses; Microcrystalline cellulose; Polyethylene glycols
                   Dosage Form Oral Tablet
                   Company Allegiant Health
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 15 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Silicon dioxide; Cellulose, microcrystalline; Dextrose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Salado Sales
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Calcium hydrogenphosphate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 16 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Silicon dioxide; Dextrose; Microcrystalline cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Better Living Brands; Major Pharmaceuticals; Wal-Mart Stores
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Calcium hydrogenphosphate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 17 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Silicon dioxide; Microcrystalline cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company SuperValu
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Calcium hydrogenphosphate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 18 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Aluminum oxide; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Powdered cellulose; Sodium starch glycolate type a corn; Starch, corn
                   Dosage Form Oral Tablet
                   Company Fred's
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 19 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Powdered cellulose; Sodium starch glycolate type a corn; Starch, corn
                   Dosage Form Oral Tablet
                   Company Care One; Valu Merchandisers Company; Western Family Foods
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 20 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Maltodextrin; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Dextrose
                   Dosage Form Oral Tablet
                   Company DZA Brands; Hy-Vee
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Dextrin DIG Info Colon cancer Caco-2 cells (Inhibition ratio > 55 %) [8]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 21 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Silicon dioxide; Dextrose; Microcrystalline cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Army & Air Force Exchange Service
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Calcium hydrogenphosphate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 22 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Silicon dioxide; Dextrose, unspecified form; Microcrystalline cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Walgreens Company
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Calcium hydrogenphosphate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 23 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Silicon dioxide; Dextrose; Microcrystalline cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company L.N.K. International
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Calcium hydrogenphosphate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 24 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Maltodextrin; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Dextrose
                   Dosage Form Oral Tablet
                   Company L. Perrigo Company; McKesson
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Dextrin DIG Info Colon cancer Caco-2 cells (Inhibition ratio > 55 %) [8]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 25 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Maltodextrin; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Dextrose, unspecified form
                   Dosage Form Oral Tablet
                   Company Publix Super Markets
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Dextrin DIG Info Colon cancer Caco-2 cells (Inhibition ratio > 55 %) [8]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 26 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company AAA Pharmaceutical; Chain Drug Marketing Association; Kinray; Meijer
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 27 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Maltodextrin; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Dextrose
                   Dosage Form Oral Tablet
                   Company Amerisource Bergen
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Dextrin DIG Info Colon cancer Caco-2 cells (Inhibition ratio > 55 %) [8]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 28 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Maltodextrin; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Dextrose, unspecified form
                   Dosage Form Oral Tablet
                   Company H E B
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Dextrin DIG Info Colon cancer Caco-2 cells (Inhibition ratio > 55 %) [8]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 29 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Silicon dioxide; Cellulose, microcrystalline; Dextrose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Fred's
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Calcium hydrogenphosphate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 30 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Silicon dioxide; Dextrose; Microcrystalline cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Family Dollar
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Calcium hydrogenphosphate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 31 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Silicon dioxide; Dextrose, unspecified form; Microcrystalline cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Amerisource Bergen
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Calcium hydrogenphosphate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 32 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Silicon dioxide; Dextrose, unspecified form; Microcrystalline cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Harmon Stores
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Calcium hydrogenphosphate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 33 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Silicon dioxide; Cellulose, microcrystalline; Dextrose, unspecified form; Starch, corn
                   Dosage Form Oral Tablet
                   Company WinCo Foods
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Calcium hydrogenphosphate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 34 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Maltodextrin; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Dextrose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Kroger Company
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Dextrin DIG Info Colon cancer Caco-2 cells (Inhibition ratio > 55 %) [8]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 35 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Titanium dioxide; Polysorbate 80; Carnauba wax; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromelloses; Polyethylene glycols; Starch, corn
                   Dosage Form Oral Tablet
                   Company Meda Consumer Healthcare
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 36 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Dextrates; Hypromellose 2910 (15 mpa.s); Hypromellose 2910 (6 mpa.s); Polyethylene glycol 8000
                   Dosage Form Oral Tablet
                   Company Time Cap Labs
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 37 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Silicon dioxide; Carnauba wax; Dextrates; Hypromelloses; Microcrystalline cellulose; Polyethylene glycols
                   Dosage Form Oral Tablet
                   Company HealthLife of USA
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 38 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Dextrose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Great Lakes Wholesale Marketing & Sales
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 39 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company Dolgencorp
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 40 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Aluminum oxide; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company Fred's; National Distribution Network; Valu Merchandisers Company; Western Family Foods
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 41 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company Care One
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 42 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Dextrose; Starch, corn
                   Dosage Form Oral Tablet
                   Company L&R Distributors
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 43 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Dextrose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Chain Drug Consortium
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 44 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Dextrose; Microcrystalline cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Cardinal Health; McKesson
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 45 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline
                   Dosage Form Oral Tablet
                   Company CVS Pharmacy; Nash Finch Company; Rite Aid
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 46 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Cellulose, microcrystalline; Dextrose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Chain Drug Marketing Association; McKesson
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 47 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company Greenbrier International
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 48 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose; D&c yellow no. 10; Calcium stearate; Silicon dioxide; Cellulose, microcrystalline
                   Dosage Form Oral Tablet
                   Company Bell Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 49 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Magnesium stearate; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Dextrose; Hypromelloses; Polyethylene glycols; Starch, corn
                   Dosage Form Oral Tablet
                   Company Rite Aid
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 50 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Magnesium stearate; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Hypromelloses; Starch, corn
                   Dosage Form Oral Tablet
                   Company CVS Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 51 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Magnesium stearate; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Dextrose; Hypromelloses; Polyethylene glycols; Starch, corn
                   Dosage Form Oral Tablet
                   Company Walgreens Company
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 52 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Magnesium stearate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Starch, corn
                   Dosage Form Oral Tablet
                   Company SuperValu
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 53 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Magnesium stearate; Cellulose, microcrystalline; Dextrose; Hypromelloses; Polyethylene glycols; Starch, corn
                   Dosage Form Oral Tablet
                   Company Better Living Brands
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 54 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Titanium dioxide; Polyethylene glycol 300; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Dextrates
                   Dosage Form Oral Tablet
                   Company Select Corporation
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Polyethylene glycol 300 DIG Info Multidrug resistance protein 1 (Inhibition ratio = 54 %) [13]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 55 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Maltodextrin; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Dextrose
                   Dosage Form Oral Tablet
                   Company Kmart Corporation; McKesson
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Dextrin DIG Info Colon cancer Caco-2 cells (Inhibition ratio > 55 %) [8]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 56 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Maltodextrin; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Dextrose
                   Dosage Form Oral Tablet
                   Company Topco Associates
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Dextrin DIG Info Colon cancer Caco-2 cells (Inhibition ratio > 55 %) [8]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
          Caffeine 100 mg tablet Click to Show/Hide the Full List of Formulation(s):          2 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Ethyl vanillin; Lactose; Calcium carbonate; D&c yellow no. 10; Maltodextrin; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Magnesium silicate; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Acacia; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol 600
                   Dosage Form Oral Tablet
                   Company Alva-Amco Pharmacal Companies
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
FD&C blue no. 1 DIG Info Solute carrier SLCO2B1 (Ki = 13 uM) [3]
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [2]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [2]
Calcium carbonate DIG Info Carbonic anhydrase IX (Ki = 8600 nM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [2]
Ethyl vanillin DIG Info Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) [5]
Polysorbate 80 DIG Info Prostaglandin G/H synthase 1 (IC50 = 1 uM) [2]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
Dextrin DIG Info Colon cancer Caco-2 cells (Inhibition ratio > 55 %) [8]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [7]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Calcium stearate; Silicon dioxide; Cellulose, microcrystalline
                   Dosage Form Oral Tablet
                   Company Bell Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
References
1 FDA label for approved caffeine from the official website of the U.S. Food and Drug Administration.
2 The activities of drug inactive ingredients on biological targets. Science. 2020 Jul 24;369(6502):403-413.
3 Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16009-16018.
4 Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate. Bioorg Med Chem Lett. 2005 Feb 1; 15(3):567-71.
5 Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives. Bioorg Med Chem Lett. 2006 Feb; 16(3):592-5.
6 Mediation of in vitro cytochrome p450 activity by common pharmaceutical excipients. Mol Pharm. 2013 Jul 1;10(7):2739-48.
7 Effects of commonly used excipients on the expression of CYP3A4 in colon and liver cells. Pharm Res. 2010 Aug;27(8):1703-12.
8 Interactions between human multidrug resistance related protein (MRP2; ABCC2) and excipients commonly used in self-emulsifying drug delivery systems (SEDDS). Int J Pharm. 2013 Apr 15;447(1-2):192-8.
9 GABA-Activated ligand gated ion channels: medicinal chemistry and molecular biology. J Med Chem. 2000 Apr 20; 43(8):1427-47.
10 Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration. Eur J Pharm Biopharm. 2008 Sep;70(1):279-88.
11 WO patent application no. 2017162840A1, SENSITIZATION OF CANCER CELLS TO NAMPT INHIBITORS BY NICOTINIC ACID PHOSPHORIBOSYLTRANSFERASE NEUTRALIZATION.
12 Effect of excipients on breast cancer resistance protein substrate uptake activity. J Control Release. 2007 Dec 4;124(1-2):1-5.
13 The effect of polyoxyethylene polymers on the transport of ranitidine in Caco-2 cell monolayers. Int J Pharm. 2011 May 16;409(1-2):164-8.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.