Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00606) | |||||
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| Name |
Ropinirole
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| Synonyms |
Click to Show/Hide the Synonyms of This API
ropinirole; 91374-21-9; ropinirol; ReQuip; Ropinirolum; Ropinirolum [INN-Latin]; Ropinirol [INN-Spanish]; SKF 101468; 4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one; SK&F 101468; 4-(2-(dipropylamino)ethyl)indolin-2-one; UNII-030PYR8953; 4-[2-(dipropylamino)ethyl]-1,3-dihydroindol-2-one; CHEMBL589; CHEBI:8888; 030PYR8953; NCGC00015893-02; DSSTox_CID_25195; DSSTox_RID_80742; DSSTox_GSID_45195; Ropitor (TN); CAS-91374-21-9; SK&F-101468A; SK&F-101468-A; 4-(2-(Dipropylamino)ethyl)-1,3-dihydro-2H-indol-2-one; Ropinirole [USAN:INN:BAN]; Ropinirole (USAN/INN); Lopac-R-4152; Lopac0_001101; SCHEMBL35212; BIDD:GT0826; SPECTRUM1505178; GTPL7295; ZINC2041; DTXSID8045195; HSDB 8252; 2H-Indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro-; HMS2093K04; Pharmakon1600-01505178; BCP09383; Tox21_110256; BDBM50020680; NSC758917; STL454344; AKOS015843123; Tox21_110256_1; CCG-205177; DB00268; MCULE-1333778454; NSC-758917; SDCCGSBI-0051070.P002; SKF-101468; VA11691; 4-[2-(Dipropylamino)ethyl]2-indolinone; NCGC00015893-01; NCGC00015893-03; NCGC00015893-04; NCGC00015893-06; NCGC00094373-12; NCGC00096064-01; NCGC00096064-02; 4-[2-(dipropylamino)ethyl]-3H-indol-2-ol; FT-0652500; C07564; D08489; AB01563044_01; AB01563044_02; 374R219; 4-(2-dipropylaminoethyl)-1,3-dihydroindol-2-one; L000520; Q420590; SR-01000076215-3; BRD-K15933101-003-01-2; 4-[2-(dipropylamino)ethyl]-2,3-dihydro-1h-indol-2-one; 4-[2-(dipropylamino)ethyl]-1.3-dihydro-2H-indol-2-one
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| Clinical Status |
Approved
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| Disease Indication | Parkinsonism | ICD-11: 8A00 | [1] | ||
| PubChem CID | |||||
| Formula |
C16H24N2O
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| Canonical SMILES |
CCCN(CCC)CCC1=C2CC(=O)NC2=CC=C1
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| InChI |
1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19)
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| InChIKey |
UHSKFQJFRQCDBE-UHFFFAOYSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=5095"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 260.37 | Topological Polar Surface Area | 32.299 | |
| XlogP | 2.7 | Complexity | 287 | ||
| Heavy Atom Count | 19 | Rotatable Bond Count | 7 | ||
| Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 2 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
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| Ropinirole 8 mg tablet | Click to Show/Hide the Full List of Formulation(s): 10 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Glyceryl dibehenate; Magnesium stearate; Mannitol; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone; Silicon dioxide; Aluminum oxide; Hydrogenated castor oil; Hypromelloses; Polydextrose; Polyethylene glycol 8000; Vinyl acetate
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AvKARE; Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Maltodextrin; Fd&c blue no. 2; Magnesium stearate; Ferric oxide red; Titanium dioxide; Triethyl citrate; Carboxymethylcellulose sodium; Polyethylene glycol 400; Povidone k30; Silicon dioxide; Ethylcelluloses; Hydrogenated castor oil; Hypromelloses; Starch, corn
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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Anhydrous lactose; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hypromelloses
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Avera McKennan Hospital; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Lactose monohydrate; Maltodextrin; Glyceryl dibehenate; Magnesium stearate; Mannitol; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Carboxymethylcellulose sodium, unspecified form; Hydrogenated castor oil; Hypromellose 2910 (6 mpa.s); Hypromelloses; Povidones
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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Anhydrous lactose; Maltodextrin; Diethyl phthalate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Silicon dioxide; Carboxymethylcellulose sodium, unspecified form; Ethylcelluloses; Hydrogenated castor oil; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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Lactose monohydrate; Maltodextrin; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Croscarmellose sodium; Polyvinyl alcohol; Silicon dioxide; Castor oil; Hypromelloses; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AvKARE | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Anhydrous lactose; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Triethyl citrate; Carboxymethylcellulose sodium; Povidone; Silicon dioxide; Ethylcelluloses; Hypromelloses; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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Lactose monohydrate; Maltodextrin; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Castor oil; Hypromelloses; Polyethylene glycols; Polyvinyl alcohol, unspecified
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|
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Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Titanium dioxide; Carboxymethylcellulose sodium; Povidone; Silicon dioxide; Ethylcellulose (7 mpa.s); Hydrogenated castor oil; Hypromelloses; Polyethylene glycol 8000; Starch, corn
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Trigen Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Titanium dioxide; Carboxymethylcellulose sodium; Povidone; Colloidal silicon dioxide; Ethylcellulose (7 mpa.s); Hydrogenated castor oil; Hypromelloses; Polyethylene glycol 8000; Starch, corn
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Alembic Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Ropinirole 0.25 mg tablet | Click to Show/Hide the Full List of Formulation(s): 20 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; D&c red no. 27; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Zhejiang Huahai Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [7] | |||
| Drug Formulation 2 |
DFM Info
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Lactose; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Carilion Materials Management | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Indigotindisulfonate sodium; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [7] | |||
| Drug Formulation 5 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Polysorbate 80; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 6 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Hypromellose; Cellulose, microcrystalline; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromelloses
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| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 8 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Alembic Pharmaceuticals; American Health Packaging; Bryant Ranch Prepack; Heritage Pharmaceuticals; Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | CorePharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Golden State Medical Supply; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Oral Tablet | |||||
| Company | Dispensing Solution | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Citric acid monohydrate; Talc; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Ropinirole 0.5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 20 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; D&c red no. 27; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Zhejiang Huahai Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [7] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; D&c red no. 27; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polyethylene glycols
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [7] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
|
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| Dosage Form | Oral Tablet | |||||
| Company | Carilion Materials Management | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Indigotindisulfonate sodium; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Aluminum oxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s)
|
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| Dosage Form | Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Anhydrous lactose; D&c yellow no. 10; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Anhydrous lactose; D&c yellow no. 10; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Golden State Medical Supply; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Anhydrous lactose; D&c yellow no. 10; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Anhydrous lactose; Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Citric acid monohydrate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Oral Tablet | |||||
| Company | Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Anhydrous lactose; Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Citric acid monohydrate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Aluminum oxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
|
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| Dosage Form | Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Aluminum oxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Alembic Pharmaceuticals; American Health Packaging; Heritage Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Hypromellose; Cellulose, microcrystalline; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Avera McKennan Hospital; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | CorePharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Ropinirole 1 mg tablet | Click to Show/Hide the Full List of Formulation(s): 22 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; D&c red no. 27; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Zhejiang Huahai Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [7] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Carilion Materials Management | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Indigotindisulfonate sodium; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s)
|
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Indigotindisulfonate sodium; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Anhydrous lactose; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; NCS HealthCare of KY, Inc dba Vangard Labs; Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Anhydrous lactose; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
|
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| Dosage Form | Oral Tablet | |||||
| Company | Golden State Medical Supply; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Anhydrous lactose; Fd&c blue no. 1; Fd&c yellow no. 5; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
|
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| Dosage Form | Oral Tablet | |||||
| Company | West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Hypromellose; Cellulose, microcrystalline; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Polyethylene glycols
|
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Avera McKennan Hospital; Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Aluminum oxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s)
|
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| Dosage Form | Oral Tablet | |||||
| Company | GlaxoSmithKline; PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | CorePharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Anhydrous lactose; Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Citric acid monohydrate; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Glenmark Pharmaceutials; Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Hydroxypropyl cellulose (1200000 mw); Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Aluminum oxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Alembic Pharmaceuticals; Heritage Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Aluminum oxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Alembic Pharmaceuticals; American Health Packaging; Cardinal Health; Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Aluminum oxide; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
|
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Ropinirole 2 mg tablet | Click to Show/Hide the Full List of Formulation(s): 30 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; D&c red no. 27; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Zhejiang Huahai Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [7] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
|
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose, unspecified form; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
|
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Maltodextrin; Glyceryl behenate; Magnesium stearate; Mannitol; Carboxymethylcellulose sodium; Povidone; Silicon dioxide; Hydrogenated castor oil; Hypromelloses
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Anhydrous lactose; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; NCS HealthCare of KY, Inc dba Vangard Labs; Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Anhydrous lactose; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
|
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| Dosage Form | Oral Tablet | |||||
| Company | Golden State Medical Supply; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Glyceryl dibehenate; Magnesium stearate; Mannitol; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone; Silicon dioxide; Hydrogenated castor oil; Hypromelloses; Polydextrose; Polyethylene glycol 8000; Vinyl acetate
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AvKARE; Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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Lactose monohydrate; Maltodextrin; Glyceryl dibehenate; Magnesium stearate; Mannitol; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Carboxymethylcellulose sodium, unspecified form; Hydrogenated castor oil; Hypromellose 2910 (6 mpa.s); Hypromelloses; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Anhydrous lactose; Fd&c red no. 40; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hypromelloses
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Anhydrous lactose; Maltodextrin; Diethyl phthalate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Talc; Titanium dioxide; Silicon dioxide; Carboxymethylcellulose sodium, unspecified form; Ethylcelluloses; Hydrogenated castor oil; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Anhydrous lactose; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
|
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| Dosage Form | Oral Tablet | |||||
| Company | West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Lactose monohydrate; Maltodextrin; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Polyvinyl alcohol; Silicon dioxide; Castor oil; Hypromelloses; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AvKARE | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Maltodextrin; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Triethyl citrate; Carboxymethylcellulose sodium; Polyethylene glycol 400; Povidone k30; Silicon dioxide; Ethylcelluloses; Hydrogenated castor oil; Hypromelloses; Starch, corn
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Carboxymethylcellulose sodium; Polyethylene glycol 6000; Povidone; Silicon dioxide; Ethylcellulose (7 mpa.s); Hydrogenated castor oil; Hypromelloses; Starch, corn
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Trigen Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Maltodextrin; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Castor oil; Hypromelloses; Polyethylene glycols; Polyvinyl alcohol, unspecified
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Ferric oxide red; Titanium dioxide; Triethyl citrate; Carboxymethylcellulose sodium; Povidone; Silicon dioxide; Ethylcelluloses; Hypromelloses; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [7] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Carboxymethylcellulose sodium; Polyethylene glycol 6000; Povidone; Colloidal silicon dioxide; Ethylcellulose (7 mpa.s); Hydrogenated castor oil; Hypromelloses; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Alembic Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [7] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Polyethylene glycols
|
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Hypromellose; Cellulose, microcrystalline; Polyethylene glycol
|
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | CorePharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Citric acid monohydrate; Ferric oxide red; Talc; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Dispensing Solution; Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Alembic Pharmaceuticals; American Health Packaging; Bryant Ranch Prepack; Heritage Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Ropinirole 3 mg tablet | Click to Show/Hide the Full List of Formulation(s): 17 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; D&c red no. 27; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Zhejiang Huahai Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [7] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; Cochineal; Fd&c blue no. 2; Fd&c yellow no. 6; Indigotindisulfonate sodium; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Aluminum oxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s)
|
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| Dosage Form | Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Caprylic acid | DIG Info | GPCR84 receptor (Ki = 19600 nM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose, unspecified form; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Golden State Medical Supply; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
|
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| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Lactose monohydrate; D&c red no. 30; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyvinyl alcohol; Aluminum oxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [10] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose monohydrate; D&c red no. 30; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Hypromellose; Cellulose, microcrystalline; Polyethylene glycol
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [10] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Cochineal; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Polyethylene glycols
|
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| Dosage Form | Oral Tablet | |||||
| Company | Avera McKennan Hospital; Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Caprylic acid | DIG Info | GPCR84 receptor (Ki = 19600 nM) | [9] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Cochineal; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Caprylic acid | DIG Info | GPCR84 receptor (Ki = 19600 nM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose monohydrate; Cochineal; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Caprylic acid | DIG Info | GPCR84 receptor (Ki = 19600 nM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Carminic acid; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Carminic acid | DIG Info | Protein-tyrosine phosphatase 1B (IC50 = 15000 nM) | [11] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Anhydrous lactose; Lactose monohydrate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Citric acid monohydrate; Talc; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Aluminum oxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Alembic Pharmaceuticals; Heritage Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | CorePharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Aluminum oxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Alembic Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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Anhydrous lactose; Fd&c red no. 40; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
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| Dosage Form | Oral Tablet | |||||
| Company | West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Ropinirole 4 mg tablet | Click to Show/Hide the Full List of Formulation(s): 27 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; D&c red no. 27; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Zhejiang Huahai Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [7] | |||
| Drug Formulation 2 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Glyceryl dibehenate; Magnesium stearate; Mannitol; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone; Silicon dioxide; Aluminum oxide; Hydrogenated castor oil; Hypromelloses; Polydextrose; Polyethylene glycol 8000; Vinyl acetate
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AvKARE; Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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Lactose monohydrate; Maltodextrin; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Triacetin; Croscarmellose sodium; Polyvinyl alcohol; Silicon dioxide; Castor oil; Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AvKARE | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Lactose monohydrate; Maltodextrin; Fd&c blue no. 2; Fd&c yellow no. 6; Glyceryl dibehenate; Magnesium stearate; Mannitol; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Carboxymethylcellulose sodium, unspecified form; Hydrogenated castor oil; Hypromellose 2910 (6 mpa.s); Hypromelloses; Povidones
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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Lactose, unspecified form; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
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| Dosage Form | Oral Tablet | |||||
| Company | Golden State Medical Supply; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Lactose monohydrate; Maltodextrin; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Castor oil; Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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Anhydrous lactose; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triethyl citrate; Carboxymethylcellulose sodium; Povidone; Silicon dioxide; Ethylcelluloses; Hypromelloses; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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Anhydrous lactose; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hypromelloses
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Fd&c yellow no. 6; Indigotindisulfonate sodium; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Aluminum oxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 11 |
DFM Info
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Anhydrous lactose; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
|
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| Dosage Form | Oral Tablet | |||||
| Company | West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Anhydrous lactose; Maltodextrin; Diethyl phthalate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Silicon dioxide; Carboxymethylcellulose sodium, unspecified form; Ethylcelluloses; Hydrogenated castor oil; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Maltodextrin; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Triethyl citrate; Carboxymethylcellulose sodium; Polyethylene glycol 400; Povidone k30; Silicon dioxide; Ethylcelluloses; Hydrogenated castor oil; Hypromelloses; Starch, corn
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Carboxymethylcellulose sodium; Povidone; Silicon dioxide; Ethylcellulose (7 mpa.s); Hydrogenated castor oil; Hypromelloses; Polyethylene glycol 8000; Starch, corn
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Trigen Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Polyethylene glycols
|
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Hypromellose; Cellulose, microcrystalline; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromelloses
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| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Ferric oxide black; Hypromelloses; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | CorePharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Carboxymethylcellulose sodium; Povidone; Colloidal silicon dioxide; Ethylcellulose (7 mpa.s); Hydrogenated castor oil; Hypromelloses; Polyethylene glycol 8000; Starch, corn
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Alembic Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Citric acid monohydrate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 23 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Alembic Pharmaceuticals; Heritage Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Hydroxypropyl cellulose (1200000 mw); Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Ropinirole 5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 17 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; D&c red no. 27; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Zhejiang Huahai Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [7] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
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| Dosage Form | Oral Tablet | |||||
| Company | Golden State Medical Supply; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Indigotindisulfonate sodium; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
|
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| Dosage Form | Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Polyethylene glycols
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [7] | |||
| Drug Formulation 5 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Indigotindisulfonate sodium; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Aluminum oxide; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Anhydrous lactose; Lactose monohydrate; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Citric acid monohydrate; Talc; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyvinyl alcohol; Aluminum oxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Hypromellose; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polyethylene glycol
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Hydroxypropyl cellulose (1200000 mw); Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [7] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromelloses
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| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Aluminum oxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Alembic Pharmaceuticals; Heritage Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Cellulose, microcrystalline; Ferric oxide black; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | CorePharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Anhydrous lactose; Fd&c blue no. 2; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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|
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Ropinirole 12 mg tablet | Click to Show/Hide the Full List of Formulation(s): 10 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|
|||||
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Anhydrous lactose; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hypromelloses
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|
|||||
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 2; Glyceryl dibehenate; Magnesium stearate; Mannitol; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone; Silicon dioxide; Aluminum oxide; Hydrogenated castor oil; Hypromelloses; Polydextrose; Polyethylene glycol 8000; Vinyl acetate
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AvKARE; Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|
|||||
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Lactose monohydrate; Maltodextrin; Fd&c blue no. 2; Glyceryl dibehenate; Magnesium stearate; Mannitol; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Carboxymethylcellulose sodium, unspecified form; Hydrogenated castor oil; Hypromellose 2910 (6 mpa.s); Hypromelloses; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|
|||||
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Maltodextrin; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triethyl citrate; Carboxymethylcellulose sodium; Polyethylene glycol 400; Povidone k30; Silicon dioxide; Ethylcelluloses; Hydrogenated castor oil; Hypromelloses; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Carboxymethylcellulose sodium; Polyethylene glycol 6000; Povidone; Silicon dioxide; Ethylcellulose (7 mpa.s); Hydrogenated castor oil; Hypromelloses; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Trigen Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|
|||||
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Anhydrous lactose; Maltodextrin; Diethyl phthalate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Silicon dioxide; Carboxymethylcellulose sodium, unspecified form; Ethylcelluloses; Hydrogenated castor oil; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Anhydrous lactose; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triethyl citrate; Carboxymethylcellulose sodium; Povidone; Silicon dioxide; Ethylcelluloses; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|
|||||
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Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Carboxymethylcellulose sodium; Polyethylene glycol 6000; Povidone; Colloidal silicon dioxide; Ethylcellulose (7 mpa.s); Hydrogenated castor oil; Hypromelloses; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Alembic Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [7] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Maltodextrin; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Polyvinyl alcohol; Silicon dioxide; Castor oil; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AvKARE | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|
|||||
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Lactose monohydrate; Maltodextrin; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Castor oil; Hypromelloses; Polyethylene glycols; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Ropinirole 6 mg tablet | Click to Show/Hide the Full List of Formulation(s): 10 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|
|||||
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Anhydrous lactose; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hypromelloses
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Glyceryl dibehenate; Magnesium stearate; Mannitol; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone; Silicon dioxide; Hydrogenated castor oil; Hypromelloses; Polydextrose; Polyethylene glycol 8000; Vinyl acetate
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AvKARE; Watson Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Anhydrous lactose; Maltodextrin; Diethyl phthalate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Carboxymethylcellulose sodium, unspecified form; Ethylcelluloses; Hydrogenated castor oil; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Maltodextrin; Glyceryl dibehenate; Magnesium stearate; Mannitol; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Carboxymethylcellulose sodium, unspecified form; Hydrogenated castor oil; Hypromellose 2910 (6 mpa.s); Hypromelloses; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | GlaxoSmithKline | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|
|||||
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Maltodextrin; Magnesium stearate; Titanium dioxide; Triethyl citrate; Carboxymethylcellulose sodium; Polyethylene glycol 400; Povidone k30; Silicon dioxide; Ethylcelluloses; Hydrogenated castor oil; Hypromelloses; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Lactose monohydrate; Maltodextrin; Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Polyvinyl alcohol; Silicon dioxide; Castor oil; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AvKARE | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|
|||||
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Lactose monohydrate; Maltodextrin; Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Castor oil; Hypromelloses; Polyethylene glycols; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Titanium dioxide; Triethyl citrate; Carboxymethylcellulose sodium; Povidone; Silicon dioxide; Ethylcelluloses; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|
|||||
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Magnesium stearate; Titanium dioxide; Carboxymethylcellulose sodium; Povidone; Silicon dioxide; Ethylcellulose (7 mpa.s); Hydrogenated castor oil; Hypromelloses; Polyethylene glycol 8000; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Trigen Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|
|||||
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Magnesium stearate; Titanium dioxide; Carboxymethylcellulose sodium; Povidone; Colloidal silicon dioxide; Ethylcellulose (7 mpa.s); Hydrogenated castor oil; Hypromelloses; Polyethylene glycol 8000; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Alembic Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
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