Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00437) | |||||
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| Name |
Minocycline
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| Synonyms |
Click to Show/Hide the Synonyms of This API
minocycline; 10118-90-8; Minocyclin; Minociclina; Minocin; Minomycin; Dynacin; Minocyn; CL 59806; 7-Dimethylamino-6-demethyl-6-deoxytetracycline; UNII-FYY3R43WGO; CHEBI:50694; FYY3R43WGO; Tri-minocycline; Minocyclinum; Minocyclinum [INN-Latin]; NCGC00183044-01; Borymycin; Minociclina [INN-Spanish]; minociclinum; Minocline; HSDB 3130; NSC-141993; Minocin (Hydrochloride); Vectrin (Hydrochloride); Minocycline (USAN/INN); BRN 3077644; Lactoferrin B & Minocycline; Lactoferrin H & Minocycline; Minocycline [USAN:INN:BAN]; SR-05000001675; (minocycline); NSC141993; Spectrum_000967; Prestwick0_000315; Prestwick1_000315; Prestwick2_000315; Spectrum2_001047; Spectrum3_000508; Spectrum4_000062; Spectrum5_001293; SCHEMBL4042; CHEMBL1434; DSSTox_CID_25033; DSSTox_RID_80650; DSSTox_GSID_45033; SCHEMBL24315; BSPBio_002035; KBioGR_000583; KBioSS_001447; cc-666; ls-007; CHEMBL69484; DivK1c_000450; SPBio_000974; SPBio_002529; DTXSID1045033; SCHEMBL16681149; BCBcMAP01_000027; GTPL10831; KBio1_000450; KBio2_001447; KBio2_004015; KBio2_006583; KBio3_001535; NINDS_000450; HMS2090D03; KUC106429N; KSC-12-231B; ZINC4019704; Tox21_113643; BDBM50103599; LMPK07000002; ZINC14879992; AKOS015969674; ZINC100409820; BCP9000928; CL59806; DB01017; IDI1_000450; SMP1_000191; NCGC00178854-01; NCGC00178854-02; NCGC00188954-01; AC-30184; CL-59806; SBI-0051449.P003; CAS-10118-90-8; AM20090714; 1371-EP2269978A2; 1371-EP2269985A2; 1371-EP2269991A2; 1371-EP2272832A1; 1371-EP2284150A2; 1371-EP2284151A2; 1371-EP2284152A2; 1371-EP2284153A2; 1371-EP2284155A2; 1371-EP2284156A2; 1371-EP2284164A2; 1371-EP2287140A2; 1371-EP2287148A2; 1371-EP2287150A2; 1371-EP2289871A1; 1371-EP2292590A2; 1371-EP2292612A2; 1371-EP2295402A2; 1371-EP2295419A2; 1371-EP2295426A1; 1371-EP2295427A1; 1371-EP2298732A1; 1371-EP2301534A1; 1371-EP2301912A2; 1371-EP2301913A1; 1371-EP2301914A1; 1371-EP2301916A2; 1371-EP2305637A2; 1371-EP2308832A1; 1371-EP2308863A1; 1371-EP2311451A1; 1371-EP2311796A1; 1371-EP2311797A1; 1371-EP2311798A1; 1371-EP2311799A1; 1371-EP2316450A1; 18M908; C07225; D05045; AB00053501-03; AB00053501_04; AB00053501_05; Q415336; J-500789; SR-05000001675-3
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| Clinical Status |
Approved
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| Disease Indication | Streptococcus bacterial infection | ICD-11: 1C41 | [1] | ||
| PubChem CID | |||||
| Formula |
C23H27N3O7
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| Canonical SMILES |
CN(C)[C@H]1[C@@H]2C[C@@H]3CC4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)N(C)C
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| InChI |
1S/C23H27N3O7/c1-25(2)12-5-6-13(27)15-10(12)7-9-8-11-17(26(3)4)19(29)16(22(24)32)21(31)23(11,33)20(30)14(9)18(15)28/h5-6,9,11,17,27-28,31,33H,7-8H2,1-4H3,(H2,24,32)/t9-,11-,17-,23-/m0/s1
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| InChIKey |
FFTVPQUHLQBXQZ-KVUCHLLUSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=54675783"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 457.5 | Topological Polar Surface Area | 165 | |
| XlogP | -0.6 | Complexity | 971 | ||
| Heavy Atom Count | 33 | Rotatable Bond Count | 3 | ||
| Hydrogen Bond Donor Count | 5 | Hydrogen Bond Acceptor Count | 9 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
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| Minocycline 50 mg capsule | Click to Show/Hide the Full List of Formulation(s): 18 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; D&c red no. 33; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Povidone; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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D&c yellow no. 10; Fd&c red no. 40; D&c red no. 33; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Indigotindisulfonate sodium; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Aluminum oxide; Gelatin; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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D&c yellow no. 10; Fd&c red no. 40; D&c red no. 33; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Indigotindisulfonate sodium; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Gelatin, unspecified; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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D&c yellow no. 10; Fd&c red no. 40; D&c red no. 33; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Gelatin; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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D&c yellow no. 10; Fd&c red no. 40; D&c red no. 33; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Gelatin; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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Sodium lauryl sulfate; Butyl alcohol; D&c red no. 33; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Alcohol; Gelatin; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [7] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Sodium lauryl sulfate; Butyl alcohol; D&c red no. 33; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Alcohol; Gelatin, unspecified; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [7] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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D&c red no. 28; Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Gelatin; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Global Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Silicon dioxide; Gelatin; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | A-S Medication Solutions; Actavis Pharma; AvPAK; Bryant Ranch Prepack; Department of State Health Services, Pharmacy Branch; Lake Eire Medical & Surgical Supply DBA Quality Care Products; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Silicon dioxide; Gelatin, unspecified; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Gelatin; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Alvogen | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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D&c yellow no. 10; Fd&c blue no. 1; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Gelatin, unspecified
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| Dosage Form | Oral Capsule | |||||
| Company | Onset Dermatologics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Drug Formulation 13 |
DFM Info
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D&c yellow no. 10; Fd&c blue no. 1; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Gelatin
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| Dosage Form | Oral Capsule | |||||
| Company | Triax Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Drug Formulation 14 |
DFM Info
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Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin, unspecified; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Denton Pharma; NuCare Pharmaceuticals; Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Aidarex Pharmaceuticals; Bryant Ranch Prepack; Physicians Total Care; Proficient Rx; Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
|
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| Dosage Form | Oral Capsule | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Gelatin; Starch, corn
|
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| Dosage Form | Oral Capsule | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Minocycline 100 mg capsule | Click to Show/Hide the Full List of Formulation(s): 22 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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D&c red no. 28; Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Povidone; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | NuCare Pharmaceuticals; Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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D&c red no. 28; Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Gelatin, unspecified; Microcrystalline cellulose; Povidone, unspecified; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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D&c red no. 28; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Indigotindisulfonate sodium; Magnesium stearate; Ammonia; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Gelatin, unspecified; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Avera McKennan Hospital; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Alcohol; Gelatin; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Aurobindo Pharma; Clinical Solutions Wholesale; DirectRX; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [7] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Alcohol; Gelatin, unspecified; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Preferred Pharamaceuticals; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [7] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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D&c red no. 28; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ammonia; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Aluminum oxide; Gelatin; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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D&c red no. 28; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ammonia; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Gelatin; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Gelatin; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | A-S Medication Solutions; Actavis Pharma; American Health Packaging; Aphena Pharma Solutions-Tennessee; AvPAK; Carilion Materials Management; Dispensing Solution; Lake Eire Medical & Surgical Supply DBA Quality Care Products; PD-Rx Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Silicon dioxide; Gelatin; Starch, corn
|
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| Dosage Form | Oral Capsule | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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Sodium lauryl sulfate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Gelatin; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Alvogen | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Gelatin; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Global Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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D&c yellow no. 10; Fd&c blue no. 1; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Gelatin, unspecified
|
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| Dosage Form | Oral Capsule | |||||
| Company | Onset Dermatologics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Drug Formulation 14 |
DFM Info
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D&c yellow no. 10; Fd&c blue no. 1; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Gelatin
|
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| Dosage Form | Oral Capsule | |||||
| Company | Aphena Pharma Solutions-Tennessee | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c blue no. 1; Titanium dioxide; Gelatin
|
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| Dosage Form | Oral Capsule | |||||
| Company | Onset Dermatologics; Triax Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Drug Formulation 16 |
DFM Info
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Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin, unspecified; Shellac; Starch, corn
|
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| Dosage Form | Oral Capsule | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | A-S Medication Solutions; Clinical Solutions Wholesale; Denton Pharma; Lake Eire Medical & Surgical Supply DBA Quality Care Products; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; RemedyRepack; Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Aidarex Pharmaceuticals; Bryant Ranch Prepack; Clinical Solutions Wholesale; Kaiser Foundation Hospitals; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Liberty Pharmaceuticals; Physicians Total Care; Proficient Rx; Ranbaxy Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin, unspecified; Shellac; Starch, corn
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Preferred Pharamaceuticals; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | AvKARE | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Minocycline 45 mg capsule | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Colloidal silicon dioxide; Gelatin; Hypromelloses; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Ranbaxy Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Minocycline 75 mg capsule | Click to Show/Hide the Full List of Formulation(s): 11 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Povidone; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Shellac; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Indigotindisulfonate sodium; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Gelatin, unspecified; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Silicon dioxide; Gelatin; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Actavis Pharma; Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Sodium lauryl sulfate; Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Alcohol; Gelatin; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [7] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Gelatin; Starch, corn
|
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| Dosage Form | Oral Capsule | |||||
| Company | Alvogen | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Gelatin; Starch, corn
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|||||
| Dosage Form | Oral Capsule | |||||
| Company | Global Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c blue no. 1; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Gelatin
|
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| Dosage Form | Oral Capsule | |||||
| Company | Onset Dermatologics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Physicians Total Care; Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Minocycline 135 mg capsule | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Colloidal silicon dioxide; Gelatin; Hypromelloses; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Ranbaxy Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Minocycline 90 mg capsule | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Colloidal silicon dioxide; Gelatin; Hypromelloses; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Ranbaxy Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Minocycline 100 mg tablet | Click to Show/Hide the Full List of Formulation(s): 8 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Crospovidone; Polyethylene glycol 6000; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Crospovidone; Polyethylene glycol 6000; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Povidones; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Polysorbate 80; Povidone; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Polysorbate 80; Povidone; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Cellulose, microcrystalline; Colloidal silicon dioxide; Povidone k29/32; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | AvKARE | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Povidones; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Minocycline 50 mg tablet | Click to Show/Hide the Full List of Formulation(s): 7 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Crospovidone; Polyethylene glycol 6000; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Crospovidone; Polyethylene glycol 6000; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Fd&c yellow no. 5; Magnesium stearate; Titanium dioxide; Povidone; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Povidones; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Cellulose, microcrystalline; Colloidal silicon dioxide; Povidone k29/32; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | AvKARE | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Povidones; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Minocycline 75 mg tablet | Click to Show/Hide the Full List of Formulation(s): 6 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Crospovidone; Polyethylene glycol 6000; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Torrent Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Crospovidone; Polyethylene glycol 6000; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromelloses
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Povidones; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Polysorbate 80; Povidone; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Povidones; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Minocycline 80 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Titanium dioxide; Triacetin; Polyethylene glycol 3350; Hypromellose 2910 (50 mpa.s)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Valeant Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Minocycline 65 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 1; Fd&c blue no. 2; Titanium dioxide; Triacetin; Polyethylene glycol 3350; Hypromellose 2910 (50 mpa.s)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Impax Generics; Valeant Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Minocycline 90 mg tablet | Click to Show/Hide the Full List of Formulation(s): 8 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose 2208 (15000 mpa.s); Hypromellose 2910 (15 mpa.s)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triacetin; Silicon dioxide; Hypromelloses; Polyethylene glycols; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Polyethylene glycol 3350; Silicon dioxide; Hypromellose 2208 (4000 mpa.s); Hypromellose 2910 (50 mpa.s)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Ascend Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Polyethylene glycol 3350; Silicon dioxide; Hypromellose 2208 (4000 mpa.s); Hypromellose 2910 (15 mpa.s); Hypromellose 2910 (6 mpa.s)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | PruGen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Polyethylene glycol 3350; Colloidal silicon dioxide; Hypromellose 2208 (4000 mpa.s); Hypromellose 2910 (15 mpa.s); Hypromellose 2910 (6 mpa.s)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Global Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Ferric oxide yellow; Titanium dioxide; Triacetin; Polyethylene glycol 3350; Hypromellose 2910 (50 mpa.s)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Valeant Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Minocycline 105 mg tablet | Click to Show/Hide the Full List of Formulation(s): 2 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sodium stearyl fumarate; Isopropyl alcohol; Talc; Triethyl citrate; Water; Polyethylene glycol 400; Cellulose, microcrystalline; Ethylcellulose (10 mpa.s); Hydroxypropyl cellulose (type h); Hypromellose 2910 (15 mpa.s); Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [7] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; D&c red no. 27; Fd&c blue no. 1; Titanium dioxide; Triacetin; Polyethylene glycol 3350; Hypromellose 2910 (50 mpa.s)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Valeant Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [3] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Minocycline 135 mg tablet | Click to Show/Hide the Full List of Formulation(s): 9 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sodium stearyl fumarate; Isopropyl alcohol; Talc; Triethyl citrate; Water; Polyethylene glycol 400; Cellulose, microcrystalline; Ethylcellulose (10 mpa.s); Hydroxypropyl cellulose (type h); Hypromellose 2910 (15 mpa.s); Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [7] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triacetin; Silicon dioxide; Hypromelloses; Polyethylene glycols; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Triacetin; Polyethylene glycol 3350; Silicon dioxide; Hypromellose 2208 (4000 mpa.s); Hypromellose 2910 (50 mpa.s)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Ascend Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Triacetin; Polyethylene glycol 3350; Silicon dioxide; Hypromellose 2208 (4000 mpa.s); Hypromellose 2910 (15 mpa.s); Hypromellose 2910 (6 mpa.s)
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | PruGen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|
|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Triacetin; Polyethylene glycol 3350; Colloidal silicon dioxide; Hypromellose 2208 (4000 mpa.s); Hypromellose 2910 (15 mpa.s); Hypromellose 2910 (6 mpa.s)
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|
|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose 2208 (15000 mpa.s); Hypromellose 2910 (15 mpa.s)
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|
|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Triacetin; Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Global Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Ferric oxide red; Titanium dioxide; Triacetin; Polyethylene glycol 3350; Hypromellose 2910 (50 mpa.s)
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|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Valeant Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Minocycline 115 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 1; Fd&c blue no. 2; Titanium dioxide; Triacetin; Hypromellose 2910 (50 mpa.s)
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|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Impax Generics; Valeant Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Minocycline 55 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c red no. 40; Titanium dioxide; Triacetin; Polyethylene glycol 3350; Hypromellose 2910 (50 mpa.s)
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|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Valeant Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Minocycline 45 mg tablet | Click to Show/Hide the Full List of Formulation(s): 8 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|
|||||
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Lactose monohydrate; Magnesium stearate; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triacetin; Silicon dioxide; Hypromelloses; Polyethylene glycols; Shellac
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose 2208 (15000 mpa.s); Hypromellose 2910 (15 mpa.s)
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose 2208 (4000 mpa.s); Hypromellose 2910 (50 mpa.s)
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Ascend Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|
|||||
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose 2208 (4000 mpa.s); Hypromellose 2910 (15 mpa.s)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | PruGen Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|
|||||
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Magnesium stearate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|
|||||
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Triacetin; Colloidal silicon dioxide; Hypromellose 2208 (4000 mpa.s); Hypromellose 2910 (15 mpa.s)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|
|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Global Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Ferrosoferric oxide; Titanium dioxide; Triacetin; Hypromellose 2910 (50 mpa.s)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Valeant Pharmaceuticals | |||||
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