Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00726) | |||||
|---|---|---|---|---|---|
| Name |
Verapamil
|
||||
| Synonyms |
Click to Show/Hide the Synonyms of This API
VERAPAMIL; 52-53-9; Iproveratril; Vasolan; Dilacoran; Isoptin; Falicard; Finoptin; Isoptine; Lekoptin; Verapamilo; Verapamilum; Isotopin; Securon; Verelan; Calcan; Cardibeltin; Izoptin; CP-16533-1; Covera-HS; Verpamil; Verelan PM; Cardiagutt; Berkatens; Dignover; Geangin; Veramex; Quasar; Univer; Novo-Veramil; Apo-Verap; Isoptin SR; Nu-Verap; Calan SR; Isoptimo; (+/-)-Verapamil hydrochlorid; CHEBI:77733; Cardiabeltin; Cardioprotect; Durasoptin; Hexasoptin; Veratensin; Veroptinstada; Calaptin; Caveril; Civicor; Coraver; Corpamil; Harteze; Hormitol; Ikapress; Inselon; Isoptino; Jenapamil; Lodixal; Magotiron; Praecicor; Robatelan; Vasomil; Vasopten; Verabeta; Veracor; Verahexal; Veraloc; Veramil; Verapin; Verasal; Verasifar; Verdilac; Vetrimil; Akilen; Elthon; Flamon; Ikacor; Univex; Vortac; Civicor Retard; Isoptin Retard; Manidon Retard; Vera-Sanorania; Verapamil Acis; Verapamil Atid; Verapamil Ebewe; Verapamil Riker; Verapamil Verla; (+/-)-Verapamil;CP-16533-1; Verapamil Basics; Verapamil Nordic; Verapamil-AbZ; Novapamyl LP; Verapamil AL; Verapamil NM; Verapamil PB; Verapamil SR; Cordilox SR; Dilacoran HTA; Veracaps SR; Verapamil MSD; Verapamilum [INN-Latin]; Arpamyl LP; Hexasoptin Retard; Verapamil Henning; Verelan SR; NCGC00016083-09; Verapamilo [INN-Spanish]; Verapamil Injection; CP-16,533-1; Verapamil NM Pharma; Calaptin 240 SR; Verapress 240 SR; DSSTox_CID_21152; DSSTox_RID_79636; DSSTox_GSID_41152; (+/-)-VERAPAMIL; Verapamil [USAN:INN:BAN]; dl-Verapamil; r,s-verapamil; CAS-52-53-9; CCRIS 6749; NSC272366; Verapamil (USAN/INN); EINECS 200-145-1; NSC 272306NA; EINECS 260-462-6; Calan (Salt/Mix); Akilen (Salt/Mix); Isoptin (Salt/Mix); Cordilox (Salt/Mix); delta-365; Covera-HS (Salt/Mix); Prestwick0_000141; Prestwick1_000141; Prestwick2_000141; Prestwick3_000141; Spectrum2_001740; Spectrum4_000906; Spectrum5_001786; CP 16533-1; CHEMBL6966; Lopac0_001237; SCHEMBL16742; BSPBio_000242; BSPBio_001513; BSPBio_002358; KBioGR_000233; KBioGR_001372; KBioGR_002343; KBioSS_000233; KBioSS_002346; 56949-77-0; MLS006011414; DivK1c_000399; SPBio_001820; SPBio_002181; BPBio1_000268; GTPL2406; CP 16533-1 (Verapamil); DTXSID9041152; SCHEMBL13287282; (A+/-)-Verapamil hydrochloride; BDBM81939; HSDB 3928; KBio1_000399; KBio2_000233; KBio2_002343; KBio2_002801; KBio2_004911; KBio2_005369; KBio2_007479; KBio3_000465; KBio3_000466; KBio3_002823; cMAP_000023; NINDS_000399; NSC-272306NA; Bio1_000425; Bio1_000914; Bio1_001403; Bio2_000233; Bio2_000713; HMS1791L15; HMS1989L15; HMS2089H17; HMS3402L15; Tox21_110300; NSC_62969; STK538085; AKOS005468962; Tox21_110300_1; CCG-205311; DB00661; MCULE-3016077278; SDCCGSBI-0051204.P005; CAS_52-53-9; IDI1_000399; IDI1_033983; NCGC00016083-04; NCGC00016083-05; NCGC00016083-06; NCGC00016083-07; NCGC00016083-08; NCGC00016083-10; NCGC00016083-11; NCGC00016083-13; NCGC00016083-14; NCGC00016083-15; NCGC00016083-16; NCGC00016083-17; NCGC00016083-18; NCGC00016083-20; NCGC00016083-25; NCGC00016083-34; NCGC00024710-04; NCGC00024710-05; NCGC00024710-06; NCGC00024710-07; NCGC00024710-08; NCGC00024710-09; NCGC00344584-01; AC-16016; BP-21223; HY-14275; NCI60_020143; SMR001550201; SBI-0051204.P003; CP-165331; AB00053495; CS-0002967; FT-0603225; FT-0675801; ST50826367; 1394-EP2270011A1; 1394-EP2272841A1; 1394-EP2272972A1; 1394-EP2272973A1; 1394-EP2275420A1; 1394-EP2277865A1; 1394-EP2277872A1; 1394-EP2280008A2; 1394-EP2298742A1; 1394-EP2298764A1; 1394-EP2298765A1; 1394-EP2298776A1; 1394-EP2298779A1; 1394-EP2301923A1; 1394-EP2301931A1; 1394-EP2301936A1; 1394-EP2305648A1; 1394-EP2314585A1; 1394-EP2316832A1; 1394-EP2316833A1; 52V114; C07188; D02356; AB00053495-20; AB00053495_21; L001330; Q410291; BRD-A09533288-001-02-7; BRD-A09533288-003-05-6; CP-165331 / CP-16533-1; F2173-0851; VERAPAMIL, Dexverapamil, Verapamyl hydrochloride, VERAPAMIL HYDROCHLORIDE
|
||||
| Clinical Status |
Approved
|
||||
| Disease Indication | Essential hypertension | ICD-11: BA00 | [1] | ||
| PubChem CID | |||||
| Formula |
C27H38N2O4
|
||||
| Canonical SMILES |
CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC
|
||||
| InChI |
1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3
|
||||
| InChIKey |
SGTNSNPWRIOYBX-UHFFFAOYSA-N
|
||||
| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=2520"></iframe>
|
 |
|||
| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 454.6 | Topological Polar Surface Area | 64 | |
| XlogP | 3.8 | Complexity | 606 | ||
| Heavy Atom Count | 33 | Rotatable Bond Count | 13 | ||
| Hydrogen Bond Donor Count | 0 | Hydrogen Bond Acceptor Count | 6 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
|---|---|---|---|---|---|---|
| Verapamil 200 mg capsule | Click to Show/Hide the Full List of Formulation(s): 4 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
 click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Oleic acid; D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Maltodextrin; D&c red no. 33; Dibutyl sebacate; Diethyl phthalate; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Povidone; Silicon dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Methacrylic acid - methyl methacrylate copolymer (1:2); Polyethylene glycols; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [4] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Oleic acid; D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Maltodextrin; D&c red no. 33; Dibutyl sebacate; Diethyl phthalate; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Ethylcellulose, unspecified; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Methacrylic acid - methyl methacrylate copolymer (1:2); Polyethylene glycol, unspecified; Povidone, unspecified; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [4] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Povidone; Silicon dioxide; Gelatin; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | UCB | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Gelatin, unspecified; Povidone, unspecified; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Kremers Urban Pharmaceuticals Inc. | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Verapamil 100 mg capsule | Click to Show/Hide the Full List of Formulation(s): 5 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Oleic acid; D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Maltodextrin; D&c red no. 33; Dibutyl sebacate; Diethyl phthalate; Fd&c blue no. 1; Fd&c blue no. 2; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Povidone; Silicon dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Methacrylic acid - methyl methacrylate copolymer (1:2); Polyethylene glycols; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Oleic acid; D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Maltodextrin; D&c red no. 33; Dibutyl sebacate; Diethyl phthalate; Fd&c blue no. 1; Fd&c blue no. 2; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Ethylcellulose, unspecified; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Methacrylic acid - methyl methacrylate copolymer (1:2); Polyethylene glycol, unspecified; Povidone, unspecified; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Oleic acid; D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Maltodextrin; D&c red no. 33; Dibutyl sebacate; Diethyl phthalate; Fd&c blue no. 1; Fd&c blue no. 2; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Methacrylic acid - methyl methacrylate copolymer (1:2); Polyethylene glycols; Povidones; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Avera McKennan Hospital | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Povidone; Silicon dioxide; Gelatin; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | UCB | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 5 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Gelatin, unspecified; Povidone, unspecified; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Kremers Urban Pharmaceuticals Inc. | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Verapamil 300 mg capsule | Click to Show/Hide the Full List of Formulation(s): 5 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Oleic acid; D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Maltodextrin; D&c red no. 33; Dibutyl sebacate; Diethyl phthalate; Fd&c blue no. 1; Fd&c blue no. 2; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Povidone; Silicon dioxide; Silicon dioxide; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Methacrylic acid - methyl methacrylate copolymer (1:2); Polyethylene glycols; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Oleic acid; D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Maltodextrin; D&c red no. 33; Dibutyl sebacate; Diethyl phthalate; Fd&c blue no. 1; Fd&c blue no. 2; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Ethylcellulose, unspecified; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Methacrylic acid - methyl methacrylate copolymer (1:2); Polyethylene glycol, unspecified; Povidone, unspecified; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| D&C red no. 33 | DIG Info | Solute carrier SLCO2B1 (Ki = 58.1 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Povidone; Silicon dioxide; Gelatin; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | UCB | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Gelatin, unspecified; Povidone, unspecified; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Bryant Ranch Prepack; Kremers Urban Pharmaceuticals Inc. | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 5 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Fd&c blue no. 1; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Gelatin; Povidones; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Verapamil 240 mg capsule | Click to Show/Hide the Full List of Formulation(s): 3 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Oleic acid; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Maltodextrin; Sucralose; Dibutyl sebacate; Diethyl phthalate; Fd&c blue no. 1; Fd&c blue no. 2; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Fd&c green no. 3; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [9] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Fd&c blue no. 1; Propylparaben; Ferric oxide yellow; Sucrose; Talc; Titanium dioxide; Povidone; Silicon dioxide; Gelatin; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Physicians Total Care; UCB | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Fd&c blue no. 1; Propylparaben; Ferric oxide yellow; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Gelatin, unspecified; Povidone, unspecified; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Actavis Pharma; Kremers Urban Pharmaceuticals Inc. | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [3] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Verapamil 120 mg capsule | Click to Show/Hide the Full List of Formulation(s): 6 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Oleic acid; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Maltodextrin; Dibutyl sebacate; Diethyl phthalate; Fd&c blue no. 1; Fd&c blue no. 2; Ammonia; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcellulose, unspecified; Fd&c green no. 3; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol, unspecified; Povidone, unspecified; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Oleic acid; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Maltodextrin; Dibutyl sebacate; Diethyl phthalate; Fd&c blue no. 1; Fd&c blue no. 2; Ammonia; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Fd&c green no. 3; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Propylparaben; Ferric oxide yellow; Sucrose; Talc; Titanium dioxide; Povidone; Silicon dioxide; Gelatin; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Capsule | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Propylparaben; Ferric oxide yellow; Sucrose; Talc; Titanium dioxide; Povidone; Silicon dioxide; Gelatin; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | UCB | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 5 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Propylparaben; Ferric oxide yellow; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Gelatin, unspecified; Povidone, unspecified; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Actavis Pharma; Kremers Urban Pharmaceuticals Inc. | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [3] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 6 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polacrilin potassium; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Verapamil 180 mg capsule | Click to Show/Hide the Full List of Formulation(s): 4 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Oleic acid; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Maltodextrin; Dibutyl sebacate; Diethyl phthalate; Fd&c blue no. 1; Fd&c blue no. 2; Ammonia; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Fd&c green no. 3; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Propylparaben; Ferric oxide yellow; Ferrosoferric oxide; Sucrose; Talc; Titanium dioxide; Povidone; Silicon dioxide; Gelatin; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | UCB | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Propylparaben; Ferric oxide yellow; Ferrosoferric oxide; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Gelatin, unspecified; Povidone, unspecified; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Actavis Pharma; Kremers Urban Pharmaceuticals Inc. | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [3] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Propylparaben; Ferric oxide yellow; Ferrosoferric oxide; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Gelatin; Povidones; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Carilion Materials Management | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [3] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Verapamil 360 mg capsule | Click to Show/Hide the Full List of Formulation(s): 4 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Fd&c blue no. 1; Propylparaben; Ferric oxide yellow; Sucrose; Talc; Titanium dioxide; Povidone; Silicon dioxide; Gelatin; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Physicians Total Care; UCB | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Fd&c blue no. 1; Propylparaben; Ferric oxide yellow; Sucrose; Talc; Titanium dioxide; Povidone; Silicon dioxide; Gelatin; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Fd&c blue no. 1; Propylparaben; Ferric oxide yellow; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Gelatin, unspecified; Povidone, unspecified; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Actavis Pharma; Kremers Urban Pharmaceuticals Inc. | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [3] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Fumaric acid; Fd&c blue no. 1; Propylparaben; Ferric oxide yellow; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Gelatin; Povidones; Shellac; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Fumaric acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 19000 nM) | [11] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [3] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Verapamil 180 mg tablet | Click to Show/Hide the Full List of Formulation(s): 19 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Butylated hydroxytoluene; D&c red no. 30; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Sodium chloride; Titanium dioxide; Polysorbate 80; Povidone; Aluminum oxide; Cellulose acetate; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | G.D. Searle LLC Division of Pfizer Inc | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [12] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [13] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Povidone; Sodium alginate; Cellulose, microcrystalline; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 3 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Povidone; Sodium alginate; Cellulose, microcrystalline; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 4 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Hypromellose; Polysorbate 80; Povidone; Sodium alginate; Cellulose, microcrystalline; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 5 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Fd&c blue no. 1; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Povidone; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Cadila Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 6 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Sodium alginate; Cellulose, microcrystalline; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Mylan Pharamceuticals; NuCare Pharmaceuticals; RemedyRepack; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 7 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polysorbate 80; Povidone; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 8 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polysorbate 80; Povidone; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 9 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Povidone; Sodium alginate; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol 8000
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; PD-Rx Pharmaceuticals; Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 10 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Sodium alginate; Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Golden State Medical Supply; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 11 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polysorbate 80; Sodium alginate; Aluminum oxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | IVAX Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 12 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polysorbate 80; Sodium alginate; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 13 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Sodium alginate; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol 8000; Povidones
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 14 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Sodium alginate; Hypromellose, unspecified; Microcrystalline cellulose; Povidone, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 15 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Povidones
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Clinical Solutions Wholesale; Glenmark Pharmaceutials; Lake Eire Medical & Surgical Supply DBA Quality Care Products; NuCare Pharmaceuticals; Preferred Pharamaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 16 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Titanium dioxide; Povidone; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 17 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Sodium alginate; Hydroxypropyl cellulose (type h); Hypromellose 2910 (5 mpa.s); Polyethylene glycol 8000
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | American Health Packaging; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 18 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Sodium alginate; Hydroxypropyl cellulose; Hypromellose 2910 (5 mpa.s); Polyethylene glycol 8000
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Apotex; St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 19 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Talc; Titanium dioxide; Carnauba wax; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | G.D. Searle LLC Division of Pfizer Inc | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Verapamil 240 mg tablet | Click to Show/Hide the Full List of Formulation(s): 22 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Butylated hydroxytoluene; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Sodium chloride; Titanium dioxide; Polysorbate 80; Povidone; Aluminum oxide; Cellulose acetate; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | G.D. Searle LLC Division of Pfizer Inc | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [12] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Povidone; Sodium alginate; Cellulose, microcrystalline; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 3 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Fd&c blue no. 1; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Povidone; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Cadila Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 4 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Sodium alginate; Cellulose, microcrystalline; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Cardinal Health; Mylan Pharamceuticals; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 5 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Hypromellose; Povidone; Sodium alginate; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Blenheim Phamacal; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 6 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Silicon dioxide; Sodium alginate; Hydroxypropyl cellulose (type h); Hypromellose 2910 (5 mpa.s); Polyethylene glycol 8000
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 7 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Silicon dioxide; Sodium alginate; Hydroxypropyl cellulose; Hypromellose 2910 (5 mpa.s); Polyethylene glycol 8000
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 8 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Povidone; Sodium alginate; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol 8000
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals; Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 9 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Sodium alginate; Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Golden State Medical Supply; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 10 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Povidone; Sodium alginate; Aluminum oxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 11 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Povidone; Sodium alginate; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Rebel Distributors; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 12 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Povidone; Sodium alginate; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 13 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Sodium alginate; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol 8000; Povidones
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 14 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Aluminum oxide; Carnauba wax; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | G.D. Searle LLC Division of Pfizer Inc | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 15 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Sodium alginate; Aluminum oxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type e); Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 16 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Sodium alginate; Aluminum oxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | IVAX Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 17 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Polyethylene glycol 400; Povidone; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 18 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Polyethylene glycol 400; Povidone; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 19 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Sodium alginate; Hypromellose, unspecified; Microcrystalline cellulose; Povidone, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 20 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Povidones
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Blenheim Phamacal; Cardinal Health; Clinical Solutions Wholesale; Glenmark Pharmaceutials; NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 21 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Povidone; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 22 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Verapamil 120 mg tablet | Click to Show/Hide the Full List of Formulation(s): 22 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Povidone; Sodium alginate; Cellulose, microcrystalline; Polyethylene glycols
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 2 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Sodium alginate; Cellulose, microcrystalline; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 3 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c yellow no. 10; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Povidone; Sodium alginate; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol 8000
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 4 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Magnesium stearate; Calcium sulfate, unspecified form; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 5 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Magnesium stearate; Calcium sulfate, unspecified form; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 6 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Sodium alginate; Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Golden State Medical Supply; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 7 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Mineral oil; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | DirectRX; Heritage Pharmaceuticals; NuCare Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 8 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Silicon dioxide; Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Mineral oil; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 9 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Polyethylene glycol 400; Povidone; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 10 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Sodium alginate; Hypromellose, unspecified; Microcrystalline cellulose; Povidone, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Proficient Rx; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 11 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Povidones
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Glenmark Pharmaceutials; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 12 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Hypromellose; Povidone; Sodium alginate; Cellulose, microcrystalline; Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 13 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Polyethylene glycol 400; Sodium alginate; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromelloses; Povidones
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 14 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Sodium alginate; Hydroxypropyl cellulose (type h); Hypromellose 2910 (5 mpa.s); Polyethylene glycol 8000
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 15 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Sodium alginate; Hydroxypropyl cellulose; Hypromellose 2910 (5 mpa.s); Polyethylene glycol 8000
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Apotex; St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 16 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack; IVAX Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 17 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose 2910 (6 mpa.s); Polacrilin potassium; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Actavis Pharma; Avera McKennan Hospital; Blenheim Phamacal; Clinical Solutions Wholesale; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Drug Formulation 18 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polacrilin potassium; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; NCS HealthCare of KY, Inc dba Vangard Labs; Physicians Total Care; Rebel Distributors; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Drug Formulation 19 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Hydroxypropyl cellulose (1200000 mw); Microcrystalline cellulose; Polacrilin potassium; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Drug Formulation 20 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose 2910 (6 mpa.s); Polacrilin potassium; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Drug Formulation 21 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose, unspecified form; Magnesium stearate; Talc; Titanium dioxide; Gelatin, unspecified; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | G.D. Searle LLC Division of Pfizer Inc | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 22 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Talc; Titanium dioxide; Carnauba wax; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Extended Release Oral Tablet | |||||
| Company | G.D. Searle LLC Division of Pfizer Inc | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Verapamil 80 mg tablet | Click to Show/Hide the Full List of Formulation(s): 7 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Magnesium stearate; Calcium sulfate, unspecified form; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Mineral oil; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Heritage Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose 2910 (6 mpa.s); Polacrilin potassium; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Actavis Pharma; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Drug Formulation 4 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polacrilin potassium; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs; Physicians Total Care; Rebel Distributors; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Drug Formulation 5 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Hydroxypropyl cellulose (1200000 mw); Microcrystalline cellulose; Polacrilin potassium; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Drug Formulation 6 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polacrilin potassium; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Drug Formulation 7 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose, unspecified form; Magnesium stearate; Talc; Titanium dioxide; Gelatin, unspecified; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | G.D. Searle LLC Division of Pfizer Inc | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Verapamil 40 mg tablet | Click to Show/Hide the Full List of Formulation(s): 3 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Aluminum oxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose 2910 (6 mpa.s); Polacrilin potassium; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Actavis Pharma; Avera McKennan Hospital | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Drug Formulation 2 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Aluminum oxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Polacrilin potassium; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Carilion Materials Management | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Drug Formulation 3 |
DFM Info
click to show the detail info of this DFM
|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Mineral oil; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Avera McKennan Hospital; Heritage Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.