Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00717) | |||||
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| Name |
Valproic acid
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| Synonyms |
Click to Show/Hide the Synonyms of This API
VALPROIC ACID; 2-Propylpentanoic acid; 99-66-1; 2-Propylvaleric acid; Dipropylacetic acid; Depakine; Depakene; Valproate; Ergenyl; Di-n-propylacetic acid; Mylproin; Pentanoic acid, 2-propyl-; 4-Heptanecarboxylic acid; n-Dipropylacetic acid; Propylvaleric acid; Myproic Acid; Dipropylacetate; Convulex; Depakin; Di-n-propylessigsaure; Avugane; Baceca; Stavzor; Acido valproico; Kyselina 2-propylvalerova; Acide valproique; 2-n-Propyl-n-valeric acid; Acidum valproicum; Acetic acid, dipropyl-; 2,2-di-n-propylacetic acid; Valproinsaeure; Savicol; Depakine chrono; Depakin chrono; Valproic acid (USP); Abbott 44090; Acide valproique [INN-French]; Acido valproico [INN-Spanish]; Acidum valproicum [INN-Latin]; 2-PROPYL-PENTANOIC ACID; Di-n-propylessigsaure [German]; Valeric acid, 2-propyl-; divalproex; Depakene (TN); Epilim; Kyselina 2-propylvalerova [Czech]; Di-n-propylessigsaeure; VPA;2-Propylpentanoic Acid; UNII-614OI1Z5WI; MFCD00002672; NSC 93819; Delepsine; Sprinkle; Valcote; Valparin; Epilex; Vupral; CHEMBL109; (n-C3H7)2CHCOOH; 614OI1Z5WI; CHEBI:39867; NSC-93819; NCGC00091149-01; Deproic; Alti-Valproic; Novo-Valproic; Penta-Valproic; Dom-Valproic; Med Valproic; Nu-Valproic; DSSTox_CID_3733; DSSTox_RID_77171; DSSTox_GSID_23733; Valproic acid USP; PMS-Valproic Acid; 2-Propylpentanoic acid, 99%; CAS-99-66-1; Depakote (TM); SMR000499581; HSDB 3582; 2 PP (base); EINECS 202-777-3; BRN 1750447; Depacane; Novo-divalproex; Sandoz valproic; Dom-valproate; Gen-divalproex; Apo-valproic; A-44090; AI3-10500; APO-divalproex; DOM-divalproex; Epival er; PHL-valproate; PMS-valproate; PMS-Divalproex; Erganyl; Stavzor; Dom-valproic acid; Apo-valproic syrup; PHL-valproic acid; Epiject I.V.; 2-propyl-Pentanoate; Epical (TM); Epilim (Salt/Mix); Valproic acid [USAN:USP:INN:BAN]; Depacon (Salt/Mix); Convulex (Salt/Mix); Eurekene (Salt/Mix); G2M-777; Valparin (Salt/Mix); Valproic acid solution; Novo-Valproic - ECC; Spectrum_000521; Divalproex (Salt/Mix); Dom-valproic acid syrup; Ratio-Valproic - ECC; Valdisoval (Salt/Mix); ACMC-209sdq; 2 -propylpentanoic acid; di-n-propyl acetic acid; S(-)-4-En-valproate; Spectrum2_000946; Spectrum3_001733; Spectrum4_000376; DOM-valproic acid E.C.; Heptane-4-carboxylic acid; PHL-valproic acid E.C.; PMS-valproic acid E.C.; Novo-valproic soft gel cap; EC 202-777-3; SCHEMBL2275; S-2-n-Propyl-4-pentenoate; (S)-2-propyl-4-pentanoate; KBioGR_000871; KBioGR_002277; KBioSS_001001; KBioSS_002278; MLS001076682; MLS001335927; MLS001335928; MLS002415770; BIDD:GT0858; DivK1c_000273; SPBio_000912; GTPL7009; DTXSID6023733; WLN: QVY3 & 3; KBio1_000273; KBio2_001001; KBio2_002277; KBio2_003569; KBio2_004845; KBio2_006137; KBio2_007413; KBio3_002626; KBio3_002757; NIJJYAXOARWZEE-UHFFFAOYSA-; Valproic acid [USAN:BAN:INN]; NINDS_000273; HMS2089J06; HMS2231E06; HMS3259C18; HMS3370C21; HMS3715B15; HMS3885G14; ACT05281; ALBB-032973; BCP33204; NSC93819; ZINC3008621; Tox21_111091; Tox21_201963; Tox21_300603; ANW-41052; BDBM50003616; LMFA01020291; SBB065764; STL445581; AKOS009156895; Tox21_111091_1; Valproic Acid 1.0 mg/ml in Methanol; CCG-221127; CS-1765; DB00313; MCULE-7136317196; NC00584; SDCCGSBI-0050864.P004; NCGC00091149-02; NCGC00091149-03; NCGC00091149-04; NCGC00091149-05; NCGC00091149-06; NCGC00091149-08; NCGC00091149-09; NCGC00162288-07; NCGC00254365-01; NCGC00259512-01; AK128830; AS-11354; HY-10585; SBI-0050864.P003; AB0009719; Depakote, Depacon,Valproic acid Sodium salt; 791-EP2306789A1; FT-0609289; FT-0675769; 6400-EP1441224A2; 6400-EP2272537A2; 6400-EP2272827A1; 6400-EP2275420A1; 6400-EP2280008A2; 6400-EP2298764A1; 6400-EP2298765A1; 6400-EP2308867A2; 6400-EP2308870A2; 6400-EP2311494A1; 6400-EP2311840A1; 6400-EP2314585A1; 6400-EP2374790A1; A19450; C07185; D00399; AB00698315-06; Q240642; Q-200321; Sodium valproate; 2-Propylpentanoic acid sodium salt; SR-01000075242-7; F2191-0115; Z1511532065; Valproic acid, European Pharmacopoeia (EP) Reference Standard; Valproic acid, United States Pharmacopeia (USP) Reference Standard; Valproic acid, Pharmaceutical Secondary Standard; Certified Reference Material
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| Clinical Status |
Approved
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| Disease Indication | Epilepsy | ICD-11: 8A60 | [1] | ||
| PubChem CID | |||||
| Formula |
C8H16O2
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| Canonical SMILES |
CCCC(CCC)C(=O)O
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| InChI |
1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)
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| InChIKey |
NIJJYAXOARWZEE-UHFFFAOYSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=3121"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 144.21 | Topological Polar Surface Area | 37.3 | |
| XlogP | 2.8 | Complexity | 93.4 | ||
| Heavy Atom Count | 10 | Rotatable Bond Count | 5 | ||
| Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 2 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
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| Valproic acid 125 mg tablet | Click to Show/Hide the Full List of Formulation(s): 27 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Vanillin; Fd&c red no. 40; Butyl alcohol; Diethyl phthalate; Fd&c yellow no. 5; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Lecithin, soybean; Polyethylene glycol 3350; Polyvinyl alcohol; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methylene chloride; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Aurobindo Pharma; Avera McKennan Hospital; Citron Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Vanillin; Fd&c red no. 40; Butyl alcohol; Diethyl phthalate; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Lecithin, soybean; Polyethylene glycol 3350; Polyvinyl alcohol; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methylene chloride; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Avera McKennan Hospital; Citron Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Vanillin; Fd&c red no. 40; Butyl alcohol; Diethyl phthalate; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Lecithin, soybean; Polyethylene glycol 3350; Polyvinyl alcohol; Povidone k30; Silicon dioxide; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methylene chloride; Microcrystalline cellulose; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Vanillin; Fd&c red no. 40; Butyl alcohol; Diethyl phthalate; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Lecithin, soybean; Polyethylene glycol 3350; Povidone k30; Silicon dioxide; Hypromellose 2910 (15 mpa.s); Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methylene chloride; Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 5 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; Fd&c red no. 40; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 3350; Polyethylene glycol 4000; Povidone k30; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (15 mpa.s); Hypromellose phthalate (31% phthalate, 40 cst); Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 6 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Fd&c yellow no. 6; Ferrosoferric oxide; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Croscarmellose sodium; Polysorbate 80; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Copovidone k25-31; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polydextrose; Polyethylene glycols
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 7 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Vanillin; Lactose monohydrate; Sodium lauryl sulfate; Butyl alcohol; Fd&c yellow no. 6; Isopropyl alcohol; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol 3000; Povidone k29/32; Shellac; Starch, pregelatinized corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs; RemedyRepack; Unichem Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 8 |
DFM Info
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Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 2; Ammonia; Ferrosoferric oxide; Propylene glycol; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Avera McKennan Hospital; RemedyRepack; Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 9 |
DFM Info
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Vanillin; Butyl alcohol; Isopropyl alcohol; Acetone; Ferrosoferric oxide; Talc; Titanium dioxide; Hypromellose; Lecithin, soybean; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromellose phthalate (31% phthalate, 40 cst); Methylene chloride; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 10 |
DFM Info
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Sodium lauryl sulfate; Glyceryl behenate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Croscarmellose sodium; Polysorbate 80; Polyvinyl alcohol; Povidone; Silicon dioxide; Cellulose, microcrystalline; Dimethicone; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 11 |
DFM Info
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Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 2; Ammonia; Ferrosoferric oxide; Propylene glycol; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Carilion Materials Management | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 12 |
DFM Info
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Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Triethyl citrate; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid; Polyethylene glycols; Shellac; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 13 |
DFM Info
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D&c red no. 30; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Shellac; Starch, pregelatinized corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 14 |
DFM Info
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D&c red no. 30; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 15 |
DFM Info
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D&c red no. 30; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromelloses; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 16 |
DFM Info
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Vanillin; Sodium lauryl sulfate; Fd&c red no. 40; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Povidone; Silicon dioxide; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 17 |
DFM Info
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Sodium lauryl sulfate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Croscarmellose sodium; Polysorbate 80; Povidone; Silicon dioxide; Cellulose, microcrystalline; Dimethicone; Glyceryl behenate/eicosadioate; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Polyvinyl alcohol, unspecified; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 18 |
DFM Info
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Sodium lauryl sulfate; Fd&c red no. 40; Fd&c blue no. 2; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone k30; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 19 |
DFM Info
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Vanillin; Sodium lauryl sulfate; Fd&c red no. 40; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; 2-(3-oxazolidinyl)ethyl methacrylate; Povidone k12; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 20 |
DFM Info
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Vanillin; Sodium lauryl sulfate; Fd&c red no. 40; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Upsher-Smith Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 21 |
DFM Info
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Vanillin; Sodium lauryl sulfate; Fd&c red no. 40; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Upsher-Smith Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 22 |
DFM Info
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Vanillin; Sodium lauryl sulfate; Fd&c red no. 40; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Starch, corn
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| Dosage Form | Delayed Release Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 23 |
DFM Info
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Vanillin; Fd&c red no. 40; Fd&c blue no. 1; Talc; Titanium dioxide; Povidone
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| Dosage Form | Enteric Coated Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Drug Formulation 24 |
DFM Info
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Vanillin; Fd&c red no. 40; Fd&c blue no. 1; Talc; Titanium dioxide; Silicon dioxide; Diacetylated monoglycerides; Povidone, unspecified; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | AbbVie | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 25 |
DFM Info
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Sodium lauryl sulfate; Fd&c red no. 40; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Hypromelloses; Methacrylic acid; Povidones; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Qualitest Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 26 |
DFM Info
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Magnesium stearate; Talc; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid; Polyethylene glycols; Povidones; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 27 |
DFM Info
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Sodium hydroxide; Talc; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone k29/32; Starch, corn
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| Dosage Form | Delayed Release Tablet | |||||
| Company | NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Valproic acid 500 mg tablet | Click to Show/Hide the Full List of Formulation(s): 71 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Vanillin; Fd&c red no. 40; Butyl alcohol; Diethyl phthalate; Fd&c blue no. 2; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Lecithin, soybean; Polyethylene glycol 3350; Polyvinyl alcohol; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methylene chloride; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Citron Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
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Vanillin; Fd&c red no. 40; Butyl alcohol; Diethyl phthalate; Fd&c blue no. 2; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Lecithin, soybean; Polyethylene glycol 3350; Polyvinyl alcohol; Povidone k30; Silicon dioxide; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methylene chloride; Microcrystalline cellulose; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Vanillin; Fd&c red no. 40; Butyl alcohol; Diethyl phthalate; Fd&c blue no. 2; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Lecithin, soybean; Polyethylene glycol 3350; Povidone k30; Silicon dioxide; Hypromellose 2910 (15 mpa.s); Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methylene chloride; Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Shellac
|
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Vanillin; Fd&c red no. 40; Butyl alcohol; Diethyl phthalate; Fd&c blue no. 2; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Lecithin, soybean; Polyethylene glycol 3350; Povidone k30; Silicon dioxide; Hypromellose 2910 (15 mpa.s); Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methylene chloride; Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 5 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Fd&c yellow no. 6; Ferrosoferric oxide; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Croscarmellose sodium; Hypromellose; Polysorbate 80; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Copovidone; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polydextrose; Polyethylene glycol
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 6 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Phenoxyisopropanol; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Isobutyl alcohol; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Crospovidone; Lecithin, soybean; Polyvinyl alcohol; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (100 mpa.s); Peg-12 laurate; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Phenoxyisopropanol | DIG Info | Sodium channel alpha Nav1.4 (EC50 = 234422.88 nM) | [13] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 7 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Fd&c yellow no. 6; Ferrosoferric oxide; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Croscarmellose sodium; Polysorbate 80; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Copovidone k25-31; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polydextrose; Polyethylene glycols
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 8 |
DFM Info
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Vanillin; Lactose monohydrate; Sodium lauryl sulfate; Butyl alcohol; Fd&c yellow no. 6; Isopropyl alcohol; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol 3000; Povidone k29/32; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 9 |
DFM Info
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Sodium lauryl sulfate; D&c red no. 30; Butyl alcohol; Fd&c blue no. 2; Ammonia; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Contract Pharmacal; RemedyRepack; Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 10 |
DFM Info
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Vanillin; Lactose monohydrate; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Isopropyl alcohol; Ferrosoferric oxide; Propylene glycol; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol 3000; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Carilion Materials Management; Clinical Solutions Wholesale; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 11 |
DFM Info
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Vanillin; Lactose monohydrate; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Isopropyl alcohol; Ferrosoferric oxide; Propylene glycol; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol 3000; Shellac; Starch, pregelatinized corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | DirectRX; NCS HealthCare of KY, Inc dba Vangard Labs; RemedyRepack; Unichem Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 12 |
DFM Info
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Vanillin; Lactose monohydrate; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Isopropyl alcohol; Ferrosoferric oxide; Propylene glycol; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol 3000; Shellac; Starch, pregelatinized corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 13 |
DFM Info
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Vanillin; Lactose monohydrate; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Isopropyl alcohol; Ferrosoferric oxide; Propylene glycol; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol 3000; Shellac; Starch, pregelatinized corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Medsource Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 14 |
DFM Info
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Vanillin; Butyl alcohol; Isopropyl alcohol; Acetone; Ferric oxide red; Ferrosoferric oxide; Talc; Titanium dioxide; Hypromellose; Lecithin, soybean; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromellose phthalate (31% phthalate, 40 cst); Methylene chloride; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 15 |
DFM Info
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Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Shellac; Xanthan gum
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 16 |
DFM Info
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Sodium lauryl sulfate; Fd&c red no. 40; D&c red no. 27; Fd&c blue no. 2; Fd&c yellow no. 6; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Hypromelloses; Methacrylic acid; Povidones; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; Qualitest Pharmaceuticals; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [4] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 17 |
DFM Info
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Sodium lauryl sulfate; Glyceryl behenate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Croscarmellose sodium; Polysorbate 80; Polyvinyl alcohol; Povidone; Silicon dioxide; Cellulose, microcrystalline; Dimethicone; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 18 |
DFM Info
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D&c red no. 30; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Hypromellose; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Vanillin; Lactose monohydrate; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Isopropyl alcohol; Ferrosoferric oxide; Propylene glycol; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Alcohol; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol 3000; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 20 |
DFM Info
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Sodium lauryl sulfate; D&c red no. 30; Fd&c blue no. 2; Ferric oxide red; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Hypromellose; Povidone k30; Silicon dioxide; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 21 |
DFM Info
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Lactose monohydrate; Butyl alcohol; Ethyl acrylate; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Polyvinyl alcohol, unspecified; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Amneal Pharmaceuticals; Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Ethyl acrylate | DIG Info | NFE2-related factor 2 (EC50 = 5110 nM) | [14] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 22 |
DFM Info
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Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Lecithin, soybean; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Shellac; Xanthan gum
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 23 |
DFM Info
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Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Triethyl citrate; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid; Polyethylene glycols; Shellac; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cadila Healthcare; Contract Pharmacal; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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D&c red no. 30; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose phthalate (24% phthalate, 55 cst); Hypromellose, unspecified; Low-substituted hydroxypropyl cellulose, unspecified; Microcrystalline cellulose; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 25 |
DFM Info
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D&c red no. 30; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Shellac; Starch, pregelatinized corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 26 |
DFM Info
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Fd&c blue no. 1; Fd&c blue no. 2; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (100 mpa.s); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polydextrose; Polyethylene glycol 8000; Shellac; Starch, corn
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | NorthStar Rx; TYA Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [10] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 27 |
DFM Info
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Fd&c blue no. 1; Fd&c blue no. 2; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose 2208 (100 mpa.s); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Polydextrose; Polyethylene glycol 8000; Shellac; Starch, corn
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Aurobindo Pharma; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [10] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 28 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Aluminum oxide; Candelilla wax; Cellacefate; Cellulose, microcrystalline; Colloidal silicon dioxide; Dextrates; Hydroxypropyl cellulose; Hypromellose 2910 (15 mpa.s)
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Watson Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 29 |
DFM Info
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D&c red no. 30; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromelloses; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 30 |
DFM Info
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D&c red no. 30; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromelloses; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 31 |
DFM Info
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Vanillin; Sodium lauryl sulfate; Fd&c red no. 40; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Povidone; Silicon dioxide; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Contract Pharmacal; McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 32 |
DFM Info
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Sodium lauryl sulfate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Croscarmellose sodium; Polysorbate 80; Povidone; Silicon dioxide; Cellulose, microcrystalline; Dimethicone; Glyceryl behenate/eicosadioate; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Polyvinyl alcohol, unspecified; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 33 |
DFM Info
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Sodium lauryl sulfate; D&c red no. 30; Fd&c blue no. 2; Ferric oxide red; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone k30; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Clinical Solutions Wholesale; DirectRX; TYA Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Vanillin; Sodium lauryl sulfate; Fd&c red no. 40; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health; NCS HealthCare of KY, Inc dba Vangard Labs; Upsher-Smith Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 35 |
DFM Info
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|||||
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Vanillin; Sodium lauryl sulfate; Fd&c red no. 40; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Upsher-Smith Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 36 |
DFM Info
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|||||
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Oleic acid; Dibutyl sebacate; Ammonia; Titanium dioxide; Triacetin; Hypromellose; Silicon dioxide; Silicon dioxide; Cellulose, microcrystalline; Ethylcellulose; Polydextrose; Polyethylene glycol
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [9] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Vanillin; D&c red no. 30; Fd&c blue no. 2; Ferric oxide red; Talc; Titanium dioxide; Silicon dioxide; Diacetylated monoglycerides; Povidone, unspecified; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | AbbVie; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 38 |
DFM Info
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|||||
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Vanillin; D&c red no. 30; Fd&c blue no. 2; Talc; Titanium dioxide; Povidone
|
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| Dosage Form | Enteric Coated Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Drug Formulation 39 |
DFM Info
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|||||
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Sodium lauryl sulfate; Fd&c yellow no. 6; Ferric oxide yellow; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone k30; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 40 |
DFM Info
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|||||
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Lactose, unspecified form; Fd&c blue no. 1; Potassium sorbate; Ferric oxide red; Propylene glycol; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hypromellose, unspecified; Polydextrose; Polyethylene glycols
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AbbVie; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 41 |
DFM Info
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|||||
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Lactose; Fd&c blue no. 1; Potassium sorbate; Ferric oxide red; Propylene glycol; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 42 |
DFM Info
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|||||
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Oleic acid; Dibutyl sebacate; Ammonia; Titanium dioxide; Triacetin; Silicon dioxide; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hypromelloses; Polydextrose; Polyethylene glycol
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 43 |
DFM Info
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|||||
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Oleic acid; Dibutyl sebacate; Ammonia; Titanium dioxide; Triacetin; Silicon dioxide; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hypromelloses; Polydextrose; Polyethylene glycol
|
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| Dosage Form | 24 HR Extended Release Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 44 |
DFM Info
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|||||
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Fd&c blue no. 1; Sodium hydroxide; Talc; Triethyl citrate; Povidone; Silicon dioxide; Cellulose, microcrystalline; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Starch, corn
|
|||||
| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 45 |
DFM Info
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|||||
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Oleic acid; Dibutyl sebacate; Ammonia; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hypromelloses; Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 46 |
DFM Info
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|||||
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Oleic acid; Dibutyl sebacate; Ammonia; Titanium dioxide; Triacetin; Silicon dioxide; Ethylcellulose, unspecified; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Cardinal Health; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 47 |
DFM Info
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|||||
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Oleic acid; Dibutyl sebacate; Ammonia; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hydroxyethyl cellulose (100 mpa.s at 2%); Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 48 |
DFM Info
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|||||
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Oleic acid; Dibutyl sebacate; Ammonia; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 49 |
DFM Info
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|||||
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Stearic acid; Dibasic calcium phosphate dihydrate; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Copovidone; Hydrogenated cottonseed oil; Hypromelloses; Polyethylene glycols; Polyvinyl alcohol, unspecified; Xanthan gum
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|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Impax Generics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 50 |
DFM Info
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|||||
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Fd&c blue no. 1; Sodium hydroxide; Talc; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone k29/32; Starch, corn
|
|||||
| Dosage Form | Delayed Release Tablet | |||||
| Company | NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 51 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Crospovidone; Polyethylene glycol 3350; Polyethylene glycol 4000; Polyvinyl alcohol; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Hypromellose phthalate (31% phthalate, 40 cst); Shellac; Starch, corn
|
|||||
| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 52 |
DFM Info
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|||||
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Lactose monohydrate; Butyl alcohol; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Crospovidone; Lecithin, soybean; Polyvinyl alcohol; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Starch, corn
|
|||||
| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 53 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Polyethylene glycol 3350; Polyethylene glycol 4000; Povidone k30; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (6 mpa.s); Hypromellose phthalate (31% phthalate, 40 cst); Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Shellac; Starch, corn
|
|||||
| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 54 |
DFM Info
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|||||
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Glyceryl behenate; Ferrosoferric oxide; Talc; Titanium dioxide; Hypromellose; Lecithin, soybean; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Polyethylene glycol; Xanthan gum
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|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 55 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Xanthan gum
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | BluePoint Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 56 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Silicon dioxide; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols; Xanthan gum
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 57 |
DFM Info
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|||||
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Glyceryl dibehenate; Ferrosoferric oxide; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Xanthan gum
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 58 |
DFM Info
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|||||
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Glyceryl dibehenate; Ferrosoferric oxide; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Xanthan gum
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Cardinal Health; Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 59 |
DFM Info
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|||||
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Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Povidone; Silicon dioxide; Ethylcelluloses; Hydroxyethyl cellulose (4000 cps at 1%); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 60 |
DFM Info
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|||||
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Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Povidone; Silicon dioxide; Ethylcelluloses; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 61 |
DFM Info
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|||||
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Lactose; Potassium sorbate; Propylene glycol; Titanium dioxide; Silicon dioxide; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care; Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 62 |
DFM Info
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|||||
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Lactose; Potassium sorbate; Propylene glycol; Titanium dioxide; Silicon dioxide; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 63 |
DFM Info
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|||||
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Lactose; Potassium sorbate; Propylene glycol; Titanium dioxide; Silicon dioxide; Ammonium laureth-5 sulfate
|
|||||
| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 64 |
DFM Info
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|||||
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Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Cardinal Health; Contract Pharmacal; PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 65 |
DFM Info
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|||||
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Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Silicon dioxide; Ethylcellulose (10 mpa.s); Hypromellose 2208 (100 mpa.s); Polyethylene glycol 1000000; Povidone k12
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 66 |
DFM Info
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|||||
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Magnesium stearate; Talc; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid; Polyethylene glycols; Povidones; Sodium starch glycolate type a potato; Starch, corn
|
|||||
| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 67 |
DFM Info
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|||||
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Dibutyl sebacate; Ammonia; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hypromelloses; Oleanolic acid; Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 68 |
DFM Info
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|||||
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Lactose monohydrate; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 69 |
DFM Info
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|||||
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Lactose monohydrate; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (120000 mw); Hypromellose, unspecified; Microcrystalline cellulose
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 70 |
DFM Info
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|||||
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Lactose monohydrate; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hydroxyethyl cellulose (2000 cps at 1%); Hydroxypropyl cellulose (type h); Hypromelloses
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Contract Pharmacal; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 71 |
DFM Info
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|||||
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Lactose monohydrate; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hydroxyethyl cellulose (2000 cps at 1%); Hydroxypropyl cellulose (type h); Hypromelloses
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Valproic acid 250 mg tablet | Click to Show/Hide the Full List of Formulation(s): 60 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Vanillin; Butyl alcohol; Diethyl phthalate; Fd&c yellow no. 6; Isopropyl alcohol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Lecithin, soybean; Polyethylene glycol 3350; Polyvinyl alcohol; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methylene chloride; Shellac
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|||||
| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Citron Pharma; Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
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Vanillin; Butyl alcohol; Diethyl phthalate; Fd&c yellow no. 6; Isopropyl alcohol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Lecithin, soybean; Polyethylene glycol 3350; Polyvinyl alcohol; Povidone k30; Silicon dioxide; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methylene chloride; Microcrystalline cellulose; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
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Vanillin; Butyl alcohol; Diethyl phthalate; Fd&c yellow no. 6; Isopropyl alcohol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Lecithin, soybean; Polyethylene glycol 3350; Povidone k30; Silicon dioxide; Hypromellose 2910 (15 mpa.s); Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methylene chloride; Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
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Vanillin; Butyl alcohol; Diethyl phthalate; Fd&c yellow no. 6; Isopropyl alcohol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Lecithin, soybean; Polyethylene glycol 3350; Polyvinyl alcohol; Povidone k30; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydroxypropyl cellulose, low substituted; Hypromellose 2910 (15 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methylene chloride; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Drug Formulation 5 |
DFM Info
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Vanillin; Butyl alcohol; Diethyl phthalate; Fd&c yellow no. 6; Isopropyl alcohol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Lecithin, soybean; Polyethylene glycol 3350; Povidone k30; Silicon dioxide; Hypromellose 2910 (15 mpa.s); Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methylene chloride; Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Shellac
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Diethyl phthalate | DIG Info | Phosphodiesterase 4D (IC50 = 8.5 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 6 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Fd&c yellow no. 6; Ferrosoferric oxide; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Croscarmellose sodium; Hypromellose; Polysorbate 80; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Copovidone; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polydextrose; Polyethylene glycol
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 7 |
DFM Info
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Vanillin; Lactose monohydrate; Sodium lauryl sulfate; D&c red no. 30; Butyl alcohol; Fd&c blue no. 2; Isopropyl alcohol; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol 3000; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Clinical Solutions Wholesale; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 8 |
DFM Info
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Vanillin; Lactose monohydrate; Sodium lauryl sulfate; D&c red no. 30; Butyl alcohol; Fd&c blue no. 2; Isopropyl alcohol; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol 3000; Shellac; Starch, pregelatinized corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Contract Pharmacal; DirectRX; NCS HealthCare of KY, Inc dba Vangard Labs; NuCare Pharmaceuticals; Unichem Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 9 |
DFM Info
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Vanillin; Lactose monohydrate; Sodium lauryl sulfate; D&c red no. 30; Butyl alcohol; Fd&c blue no. 2; Isopropyl alcohol; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol 3000; Shellac; Starch, pregelatinized corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 10 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Indigotindisulfonate sodium; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 3350; Polyethylene glycol 4000; Povidone k30; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (15 mpa.s); Hypromellose phthalate (31% phthalate, 40 cst); Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 11 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Fd&c yellow no. 6; Ferrosoferric oxide; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Croscarmellose sodium; Polysorbate 80; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Copovidone k25-31; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polydextrose; Polyethylene glycols
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 12 |
DFM Info
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Vanillin; Butyl alcohol; Isopropyl alcohol; Acetone; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Hypromellose; Lecithin, soybean; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromellose phthalate (31% phthalate, 40 cst); Methylene chloride; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 13 |
DFM Info
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Sodium lauryl sulfate; Fd&c red no. 40; D&c red no. 27; Fd&c blue no. 2; Fd&c yellow no. 6; Ferric oxide yellow; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone k12; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [4] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 14 |
DFM Info
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Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Shellac; Xanthan gum
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 15 |
DFM Info
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Sodium lauryl sulfate; Glyceryl behenate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Croscarmellose sodium; Polysorbate 80; Polyvinyl alcohol; Povidone; Silicon dioxide; Cellulose, microcrystalline; Dimethicone; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 16 |
DFM Info
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D&c red no. 30; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Hypromellose; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 17 |
DFM Info
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Sodium lauryl sulfate; Butyl alcohol; Fd&c yellow no. 6; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Avera McKennan Hospital; Contract Pharmacal; RemedyRepack; Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 18 |
DFM Info
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Lactose monohydrate; Butyl alcohol; Ethyl acrylate; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols; Polyvinyl alcohol, unspecified; Shellac
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Amneal Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Ethyl acrylate | DIG Info | NFE2-related factor 2 (EC50 = 5110 nM) | [14] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 19 |
DFM Info
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Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Lecithin, soybean; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Shellac; Xanthan gum
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 20 |
DFM Info
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Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Talc; Triethyl citrate; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid; Polyethylene glycols; Shellac; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cadila Healthcare; Contract Pharmacal; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 21 |
DFM Info
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D&c red no. 30; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Shellac; Starch, pregelatinized corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 22 |
DFM Info
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Vanillin; Sodium lauryl sulfate; Fd&c yellow no. 6; Ferric oxide red; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Povidone; Silicon dioxide; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Contract Pharmacal; McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 23 |
DFM Info
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D&c red no. 30; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hydroxypropyl cellulose, low substituted; Hypromelloses; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 24 |
DFM Info
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D&c red no. 30; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hydroxypropyl cellulose, low substituted; Hypromelloses; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 25 |
DFM Info
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Sodium lauryl sulfate; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Croscarmellose sodium; Polysorbate 80; Povidone; Silicon dioxide; Cellulose, microcrystalline; Dimethicone; Glyceryl behenate/eicosadioate; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Polyvinyl alcohol, unspecified; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 26 |
DFM Info
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Fd&c blue no. 1; Fd&c blue no. 2; Mannitol; Propylene glycol; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (100 mpa.s); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol 8000; Shellac; Starch, corn
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [10] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 27 |
DFM Info
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Fd&c blue no. 1; Fd&c blue no. 2; Mannitol; Propylene glycol; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose 2208 (100 mpa.s); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Polyethylene glycol 8000; Shellac; Starch, corn
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Aurobindo Pharma; Bryant Ranch Prepack; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [10] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 28 |
DFM Info
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Vanillin; Lactose monohydrate; Sodium lauryl sulfate; D&c red no. 30; Fd&c blue no. 2; Ferric oxide red; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromellose 2910 (6 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol 3000; Povidone k29/32; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [12] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Drug Formulation 29 |
DFM Info
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Sodium lauryl sulfate; Fd&c yellow no. 6; Ferric oxide yellow; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone; Silicon dioxide; Hypromelloses; Methacrylic acid; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 30 |
DFM Info
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Sodium lauryl sulfate; Fd&c red no. 40; Fd&c blue no. 2; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone k30; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 31 |
DFM Info
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Vanillin; Sodium lauryl sulfate; Fd&c yellow no. 6; Ferric oxide red; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Cardinal Health; NCS HealthCare of KY, Inc dba Vangard Labs; Upsher-Smith Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 32 |
DFM Info
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Vanillin; Sodium lauryl sulfate; Fd&c yellow no. 6; Ferric oxide red; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Upsher-Smith Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 33 |
DFM Info
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Sodium lauryl sulfate; Fd&c yellow no. 6; Ferric oxide yellow; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone k30; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; Clinical Solutions Wholesale; TYA Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 34 |
DFM Info
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Sodium lauryl sulfate; Fd&c yellow no. 6; Ferric oxide yellow; Sodium bicarbonate; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Hypromelloses; Methacrylic acid; Povidones; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Qualitest Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 35 |
DFM Info
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Vanillin; Sodium lauryl sulfate; Fd&c yellow no. 6; Ferric oxide red; Sodium bicarbonate; Talc; Titanium dioxide; Triethyl citrate; Colloidal silicon dioxide; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Starch, corn
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Drug Formulation 36 |
DFM Info
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Lactose; Fd&c blue no. 1; Potassium sorbate; Propylene glycol; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Lactose, unspecified form; Fd&c blue no. 1; Potassium sorbate; Propylene glycol; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hypromellose, unspecified; Polyethylene glycols
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AbbVie; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 38 |
DFM Info
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|||||
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Oleic acid; Dibutyl sebacate; Ammonia; Titanium dioxide; Triacetin; Silicon dioxide; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hypromelloses; Polydextrose; Polyethylene glycol
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 39 |
DFM Info
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|||||
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Oleic acid; Dibutyl sebacate; Ammonia; Titanium dioxide; Triacetin; Silicon dioxide; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hypromelloses; Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 40 |
DFM Info
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|||||
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Vanillin; Fd&c yellow no. 6; Ferric oxide red; Talc; Titanium dioxide; Silicon dioxide; Diacetylated monoglycerides; Povidone, unspecified; Starch, corn
|
|||||
| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | AbbVie; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 41 |
DFM Info
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|||||
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Vanillin; Fd&c yellow no. 6; Talc; Titanium dioxide; Povidone
|
|||||
| Dosage Form | Enteric Coated Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Drug Formulation 42 |
DFM Info
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|||||
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Vanillin; Fd&c yellow no. 6; Talc; Titanium dioxide; Povidone
|
|||||
| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Drug Formulation 43 |
DFM Info
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|||||
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Oleic acid; Dibutyl sebacate; Ammonia; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hypromelloses; Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 44 |
DFM Info
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|||||
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Oleic acid; Dibutyl sebacate; Ammonia; Titanium dioxide; Triacetin; Silicon dioxide; Ethylcellulose, unspecified; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 45 |
DFM Info
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|||||
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Oleic acid; Dibutyl sebacate; Ammonia; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hydroxyethyl cellulose (100 mpa.s at 2%); Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [9] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 46 |
DFM Info
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|||||
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Stearic acid; Dibasic calcium phosphate dihydrate; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Copovidone; Hydrogenated cottonseed oil; Hypromelloses; Polyethylene glycols; Polyvinyl alcohol, unspecified; Xanthan gum
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Impax Generics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 47 |
DFM Info
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|||||
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Glyceryl behenate; Talc; Titanium dioxide; Hypromellose; Lecithin, soybean; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Polyethylene glycol; Xanthan gum
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 48 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Xanthan gum
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | BluePoint Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 49 |
DFM Info
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|||||
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Magnesium stearate; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Silicon dioxide; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols; Xanthan gum
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 50 |
DFM Info
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|||||
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Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Povidone; Silicon dioxide; Ethylcelluloses; Hydroxyethyl cellulose (4000 cps at 1%); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 51 |
DFM Info
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|||||
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Glyceryl dibehenate; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hypromelloses; Polyethylene glycols; Xanthan gum
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [7] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 52 |
DFM Info
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|||||
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Lactose; Potassium sorbate; Propylene glycol; Titanium dioxide; Titanium dioxide; Silicon dioxide; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 53 |
DFM Info
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|||||
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Ferric oxide red; Sodium hydroxide; Talc; Triethyl citrate; Povidone; Silicon dioxide; Cellulose, microcrystalline; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Starch, corn
|
|||||
| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 54 |
DFM Info
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|||||
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Lactose; Potassium sorbate; Propylene glycol; Titanium dioxide; Silicon dioxide; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 55 |
DFM Info
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|||||
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Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Silicon dioxide; Ethylcelluloses; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Avera McKennan Hospital | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 56 |
DFM Info
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|||||
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Magnesium stearate; Talc; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid; Polyethylene glycols; Povidones; Sodium starch glycolate type a potato; Starch, corn
|
|||||
| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 57 |
DFM Info
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|||||
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Lactose monohydrate; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hypromellose, unspecified; Microcrystalline cellulose
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 58 |
DFM Info
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|||||
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Lactose monohydrate; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hydroxyethyl cellulose (2000 cps at 1%); Hypromelloses
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 59 |
DFM Info
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|||||
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Lactose monohydrate; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hydroxyethyl cellulose (2000 cps at 1%); Hypromelloses
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 60 |
DFM Info
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|||||
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Ferric oxide red; Sodium hydroxide; Talc; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone k29/32; Starch, corn
|
|||||
| Dosage Form | Delayed Release Tablet | |||||
| Company | NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Valproic acid 125 mg capsule | Click to Show/Hide the Full List of Formulation(s): 12 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Oleic acid; Lactose monohydrate; Sodium lauryl sulfate; Maltodextrin; Dibutyl sebacate; Fd&c blue no. 2; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Croscarmellose sodium; Polysorbate 80; Silicon dioxide; Copovidone; Ethylcellulose, unspecified; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Polyethylene glycol, unspecified; Shellac
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [9] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [10] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [11] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Oleic acid; Lactose monohydrate; Sodium lauryl sulfate; Maltodextrin; Dibutyl sebacate; Fd&c blue no. 2; Mannitol; Ammonia; Ferric oxide red; Sodium hydroxide; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Croscarmellose sodium; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Copovidone k25-31; Ethylcelluloses; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [9] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [10] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [11] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Sodium lauryl sulfate; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Water; Silicon dioxide; Alcohol; Cellulose, microcrystalline; Gelatin; Hypromelloses; Methacrylic acid; Shellac
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | AvPAK; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Sodium lauryl sulfate; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Water; Silicon dioxide; Alcohol; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid; Microcrystalline cellulose; Shellac
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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D&c red no. 28; Fd&c blue no. 1; Magnesium stearate; Ferric oxide red; Titanium dioxide; Triethyl citrate; Silicon dioxide; Gelatin, unspecified
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | AbbVie | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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D&c red no. 28; Fd&c blue no. 1; Magnesium stearate; Ferric oxide red; Titanium dioxide; Triethyl citrate; Silicon dioxide; Gelatin
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 7 |
DFM Info
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D&c red no. 28; Fd&c blue no. 1; Magnesium stearate; Ferrosoferric oxide; Sucrose; Titanium dioxide; Triethyl citrate; Ethylcelluloses; Gelatin; Hypromelloses; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 8 |
DFM Info
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D&c red no. 28; Fd&c blue no. 1; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Triethyl citrate; Ethylcelluloses; Gelatin; Hypromelloses; Raw sugar
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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D&c red no. 28; Fd&c blue no. 1; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Triethyl citrate; Ethylcelluloses; Gelatin; Hypromelloses; Raw sugar
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 10 |
DFM Info
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Sodium lauryl sulfate; Fd&c blue no. 1; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Hypromelloses; Methacrylic acid
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 11 |
DFM Info
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Sodium lauryl sulfate; Fd&c blue no. 1; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Microcrystalline cellulose
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Fd&c yellow no. 6; Ammonia; Glycerin; Triethyl citrate; Water; Gelatin; Methacrylic acid - methyl methacrylate copolymer (1:1)
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Noven Therapeutics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Valproic acid 250 mg capsule | Click to Show/Hide the Full List of Formulation(s): 10 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Methylparaben; Fd&c yellow no. 6; Propylparaben; Ferric oxide red; Glycerin; Titanium dioxide; Corn oil; Gelatin
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| Dosage Form | Oral Capsule | |||||
| Company | AbbVie; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [15] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [2] | |||
| Drug Formulation 2 |
DFM Info
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Methylparaben; Propylparaben; Glycerin; Titanium dioxide; Corn oil; Gelatin
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| Dosage Form | Oral Capsule | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [15] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [2] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Fd&c yellow no. 6; Ammonia; Glycerin; Triethyl citrate; Water; Gelatin; Methacrylic acid - methyl methacrylate copolymer (1:1)
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|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Noven Therapeutics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Fd&c blue no. 1; Glycerin; Titanium dioxide; Water; Corn oil; Gelatin
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| Dosage Form | Oral Capsule | |||||
| Company | Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Fd&c blue no. 1; Glycerin; Titanium dioxide; Water; Corn oil; Gelatin
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| Dosage Form | Oral Capsule | |||||
| Company | Avera McKennan Hospital; Pliva | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Fd&c blue no. 1; Glycerin; Titanium dioxide; Water; Corn oil; Gelatin
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| Dosage Form | Oral Capsule | |||||
| Company | Contract Pharmacal; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Glycerin; Titanium dioxide; Gelatin; Peanut oil
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| Dosage Form | Oral Capsule | |||||
| Company | Actavis Pharma; Aphena Pharma Solutions-Tennessee; Clinical Solutions Wholesale; Contract Pharmacal; NCS HealthCare of KY, Inc dba Vangard Labs; Physicians Total Care; RemedyRepack | |||||
| Drug Formulation 8 |
DFM Info
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|||||
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Glycerin; Titanium dioxide; Gelatin; Peanut oil
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Aphena Pharma Solutions-Tennessee | |||||
| Drug Formulation 9 |
DFM Info
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|||||
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Glycerin; Titanium dioxide; Gelatin, unspecified; Peanut oil
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | RemedyRepack | |||||
| Drug Formulation 10 |
DFM Info
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|||||
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Glycerin; Titanium dioxide; Gelatin; Peanut oil
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Cardinal Health; McKesson; Mylan Pharamceuticals; NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| Valproic acid 500 mg capsule | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Fd&c yellow no. 6; Ammonia; Glycerin; Triethyl citrate; Water; Gelatin; Methacrylic acid - methyl methacrylate copolymer (1:1)
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|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Noven Therapeutics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
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