Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00419) | |||||
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| Name |
Methylphenidate
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| Synonyms |
Click to Show/Hide the Synonyms of This API
methylphenidate; Methylphenidan; Phenidylate; Concerta; Calocain; Plimasine; Meridil; Methyl phenidate; 113-45-1; Methyl phenidylacetate; Metilfenidato [Italian]; Methylphenidatum; Metilfenidato [INN-Spanish]; Methylphenidatum [INN-Latin]; Methylin; 4311/B Ciba; Methyl phenidyl acetate; methyl phenyl(piperidin-2-yl)acetate; Ritalin; Methyl alpha-phenyl-alpha-(2-piperidyl)acetate; alpha-Phenyl-2-piperidineacetic acid methyl ester; 2-Piperidineacetic acid, alpha-phenyl-, methyl ester; NCI-C56280; Methyl alpha-phenyl-alpha-2-piperidinylacetate; CHEMBL796; 2-Piperidineacetic acid, .alpha.-phenyl-, methyl ester; Methyl 2-phenyl-2-(piperidin-2-yl)acetate; Methylfenidan; CHEBI:84276; Metilfenidato; Methylphenidylacetate hydrochloride; .alpha.-Phenyl-2-piperidineacetic acid methyl ester; d-methylphenidate HCl; Daytrana (TN); HSDB 3126; Methyl (2-phenyl-2-(2-piperidyl)acetate); EINECS 204-028-6; C 4311; Methylphenidate (USAN/INN); Rubifen; alpha-Phenyl-alpha-(2-piperidyl)acetic acid methyl ester; Adhd patch; DEA No. 1724; Methylphenidate [USAN:INN:BAN]; Cotempla XR-ODT; Ritalin (Salt/Mix); Methylin (Salt/Mix); Ritaline (Salt/Mix); Centedein (Salt/Mix); Centedrin (Salt/Mix); Centedrine (Salt/Mix); SCHEMBL37178; GTPL7236; DTXSID5023299; Jornay PM (a.k.a. HLD200); BCP18286; HY-B1091; BDBM50062912; methyl alpha-piperid-2-ylphenylacetate; Methyl phenyl(2-piperidinyl)acetate #; CS-4657; DB00422; NCGC00248587-01; NCGC00248587-03; Methyl .alpha.-phenyl-2-piperidineacetate; SBI-0206868.P001; Methyl .alpha.-phenyl-2-piperidine-acetate; C07196; D04999; phenyl-piperidin-2-yl-acetic acid methyl ester; AB01563134_01; L001307; Q422112; Methyl .alpha.-phenyl-.alpha.-(2-piperidyl)acetate; Methyl .alpha.-phenyl-.alpha.-2-piperidinylacetate; BRD-A19585813-003-01-7
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| Clinical Status |
Approved
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| Disease Indication | Attention deficit hyperactivity disorder | ICD-11: 6A05 | [1] | ||
| PubChem CID | |||||
| Formula |
C14H19NO2
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| Canonical SMILES |
COC(=O)C(C1CCCCN1)C2=CC=CC=C2
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| InChI |
1S/C14H19NO2/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3
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| InChIKey |
DUGOZIWVEXMGBE-UHFFFAOYSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=4158"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 233.31 | Topological Polar Surface Area | 38.3 | |
| XlogP | 0.2 | Complexity | 249 | ||
| Heavy Atom Count | 17 | Rotatable Bond Count | 4 | ||
| Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 3 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
|---|---|---|---|---|---|---|
| Methylphenidate 27 mg tablet | Click to Show/Hide the Full List of Formulation(s): 10 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Butylated hydroxytoluene; Fd&c red no. 40; Sodium stearyl fumarate; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Silicon dioxide; Cellulose acetate; Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Sodium chloride; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose acetate; Hypromelloses; Polyethylene glycols; Polyethylene oxide 200000; Polyethylene oxide 5000000
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Trigen Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Povidone; Carnauba wax; Cellulose acetate; Hypromelloses; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [10] | |||
| Drug Formulation 4 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Povidone; Carnauba wax; Cellulose acetate; Hypromelloses; Polyethylene glycol
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [10] | |||
| Drug Formulation 5 |
DFM Info
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|
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Oleic acid; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Medium-chain triglycerides; Silicon dioxide; Ethylcellulose, unspecified; Hydroxypropyl cellulose (1200000 mw); Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Shellac
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mallinckrodt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [11] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Medium-chain triglyceride | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 36 %) | [12] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose, unspecified form; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Carnauba wax; Cellulose acetate; Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose, unspecified form; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Carnauba wax; Cellulose acetate; Hypromelloses; Poloxamer 124; Polyethylene glycols; Povidones
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose, unspecified form; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Carnauba wax; Cellulose acetate; Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Janssen Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 9 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Carboxymethylcellulose sodium; Polyethylene glycol 3350; Silicon dioxide; Cellulose, microcrystalline; Ethylcellulose (10 mpa.s); Hydroxypropyl cellulose (type h); Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromelloses; Starch, corn
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AvKARE | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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|
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 3350; Silicon dioxide; Carboxymethylcellulose sodium (0.7 carboxymethyl substitution per saccharide 400 mpa.s at 1%); Cellulose, microcrystalline; Ethylcellulose (10 mpa.s); Hydroxypropyl cellulose (type h); Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromelloses; Starch, corn
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Kremers Urban Pharmaceuticals Inc. | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Methylphenidate 54 mg tablet | Click to Show/Hide the Full List of Formulation(s): 9 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Sodium chloride; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose acetate; Hypromelloses; Polyethylene glycols; Polyethylene oxide 200000; Polyethylene oxide 5000000
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Trigen Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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|
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Povidone; Carnauba wax; Cellulose acetate; Hypromelloses; Polyethylene glycol
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [10] | |||
| Drug Formulation 3 |
DFM Info
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|
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Butylated hydroxytoluene; Sodium stearyl fumarate; Fd&c blue no. 1; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Silicon dioxide; Cellulose acetate; Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose, unspecified form; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Carnauba wax; Cellulose acetate; Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose, unspecified form; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Carnauba wax; Cellulose acetate; Hypromelloses; Poloxamer 124; Polyethylene glycols; Povidones
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|
|||||
| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose, unspecified form; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Carnauba wax; Cellulose acetate; Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Janssen Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Oleic acid; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Medium-chain triglycerides; Silicon dioxide; Ethylcellulose, unspecified; Hydroxypropyl cellulose (1200000 mw); Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Shellac
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mallinckrodt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [11] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Medium-chain triglyceride | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 36 %) | [12] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Carboxymethylcellulose sodium; Polyethylene glycol 3350; Silicon dioxide; Cellulose, microcrystalline; Ethylcellulose (10 mpa.s); Hydroxypropyl cellulose (type h); Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromelloses; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AvKARE | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 3350; Silicon dioxide; Carboxymethylcellulose sodium (0.7 carboxymethyl substitution per saccharide 400 mpa.s at 1%); Cellulose, microcrystalline; Ethylcellulose (10 mpa.s); Hydroxypropyl cellulose (type h); Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromelloses; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Kremers Urban Pharmaceuticals Inc. | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Methylphenidate 18 mg tablet | Click to Show/Hide the Full List of Formulation(s): 10 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|
|||||
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Stearic acid; Lactose; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Povidone; Carnauba wax; Cellulose acetate; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [10] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Stearic acid; Lactose; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Povidone; Carnauba wax; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [10] | |||
| Drug Formulation 3 |
DFM Info
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|
|||||
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Butylated hydroxytoluene; Sodium stearyl fumarate; Fd&c blue no. 1; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Lecithin, soybean; Silicon dioxide; Cellulose acetate; Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Stearic acid; Lactose, unspecified form; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Carnauba wax; Cellulose acetate; Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Stearic acid; Lactose, unspecified form; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Carnauba wax; Cellulose acetate; Hypromelloses; Poloxamer 124; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Stearic acid; Lactose; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Carnauba wax; Cellulose acetate; Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Avera McKennan Hospital | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Stearic acid; Lactose, unspecified form; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Carnauba wax; Cellulose acetate; Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Janssen Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Sodium chloride; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose acetate; Hypromelloses; Polyethylene glycols; Polyethylene oxide 200000; Polyethylene oxide 5000000
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Trigen Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Carboxymethylcellulose sodium; Polyethylene glycol 3350; Silicon dioxide; Cellulose, microcrystalline; Ethylcellulose (10 mpa.s); Hydroxypropyl cellulose (type h); Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromelloses; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AvKARE | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 3350; Silicon dioxide; Carboxymethylcellulose sodium (0.7 carboxymethyl substitution per saccharide 400 mpa.s at 1%); Cellulose, microcrystalline; Ethylcellulose (10 mpa.s); Hydroxypropyl cellulose (type h); Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromelloses; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Avera McKennan Hospital; Kremers Urban Pharmaceuticals Inc. | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Methylphenidate 36 mg tablet | Click to Show/Hide the Full List of Formulation(s): 9 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Stearic acid; Lactose; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Povidone; Carnauba wax; Cellulose acetate; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [10] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Stearic acid; Lactose, unspecified form; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Carnauba wax; Cellulose acetate; Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Stearic acid; Lactose, unspecified form; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Carnauba wax; Cellulose acetate; Hypromelloses; Poloxamer 124; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Stearic acid; Lactose, unspecified form; Butylated hydroxytoluene; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Carnauba wax; Cellulose acetate; Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Janssen Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Butylated hydroxytoluene; Sodium stearyl fumarate; Fd&c blue no. 1; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Silicon dioxide; Cellulose acetate; Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Butylated hydroxytoluene | DIG Info | Carbonic anhydrase II (Ki = 630 nM) | [4] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Oleic acid; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Medium-chain triglycerides; Silicon dioxide; Ethylcellulose, unspecified; Hydroxypropyl cellulose (1200000 mw); Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mallinckrodt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [11] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Medium-chain triglyceride | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 36 %) | [12] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Phosphoric acid; Succinic acid; Ferrosoferric oxide; Sodium chloride; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose acetate; Hypromelloses; Polyethylene glycols; Polyethylene oxide 200000; Polyethylene oxide 5000000
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Trigen Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Succinic acid | DIG Info | HIF-prolyl hydroxylase 2 (IC50 = 3000 nM) | [8] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Carboxymethylcellulose sodium; Polyethylene glycol 3350; Silicon dioxide; Cellulose, microcrystalline; Ethylcellulose (10 mpa.s); Hydroxypropyl cellulose (type h); Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromelloses; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AvKARE | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 3350; Silicon dioxide; Carboxymethylcellulose sodium (0.7 carboxymethyl substitution per saccharide 400 mpa.s at 1%); Cellulose, microcrystalline; Ethylcellulose (10 mpa.s); Hydroxypropyl cellulose (type h); Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromelloses; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Kremers Urban Pharmaceuticals Inc. | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Methylphenidate 17.3 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sucralose; Fructose; Magnesium stearate; Mannitol; Citric acid monohydrate; Triethyl citrate; Silicon dioxide; Crospovidone, unspecified; Ethylcellulose, unspecified; Methacrylic acid; Microcrystalline cellulose; Polyethylene glycol, unspecified; Polystyrene sulfonic acid
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Neos Therapeutics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [13] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [14] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Methylphenidate 25.9 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sucralose; Fructose; Magnesium stearate; Mannitol; Citric acid monohydrate; Triethyl citrate; Silicon dioxide; Crospovidone, unspecified; Ethylcellulose, unspecified; Methacrylic acid; Microcrystalline cellulose; Polyethylene glycol, unspecified; Polystyrene sulfonic acid
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Neos Therapeutics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [13] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [14] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Methylphenidate 8.6 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sucralose; Fructose; Magnesium stearate; Mannitol; Citric acid monohydrate; Triethyl citrate; Silicon dioxide; Crospovidone, unspecified; Ethylcellulose, unspecified; Methacrylic acid; Microcrystalline cellulose; Polyethylene glycol, unspecified; Polystyrene sulfonic acid
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Neos Therapeutics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [13] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [14] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Methylphenidate 10 mg tablet | Click to Show/Hide the Full List of Formulation(s): 22 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Sucrose; Silicon dioxide; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Sucrose; Silicon dioxide
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Talc; Polyethylene glycol 8000
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Talc; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | KVK Tech | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Anhydrous citric acid; Lactose monohydrate; Magnesium stearate; Silicon dioxide
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Nostrum Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Kyselina citronova | DIG Info | Perilipin-1 (IC50 = 3708 nM) | [15] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Stearic acid; Maltose; Aspartame; Phosphoric acid; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Chewable Tablet | |||||
| Company | GAVIS Pharmaceuticals; Novel Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [2] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Stearic acid; Maltose; Aspartame; Cellulose, microcrystalline; Guar gum; Starch, corn
|
|||||
| Dosage Form | Chewable Tablet | |||||
| Company | Shionogi | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [2] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Fd&c yellow no. 6; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | CorePharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Sucrose; Talc; Fd&c green no. 3; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Novartis Pharmaceuticals Corporation; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging; Bryant Ranch Prepack; Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Mallinckrodt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Alvogen | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lupin Pharmaceuticals; Novel Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Sucrose; Cellulose, microcrystalline; Colloidal silicon dioxide; Fd&c green no. 3
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Camber Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Magnesium stearate; Talc; Cellulose, microcrystalline; Hypromellose 2208 (15000 mpa.s)
|
|||||
| Dosage Form | 8 HR Extended Release Oral Tablet | |||||
| Company | Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Magnesium stearate; Talc; Hypromellose 2208 (15000 mpa.s); Microcrystalline cellulose
|
|||||
| Dosage Form | 8 HR Extended Release Oral Tablet | |||||
| Company | Mallinckrodt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Magnesium stearate; Talc; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | 8 HR Extended Release Oral Tablet | |||||
| Company | KVK Tech | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Magnesium stearate; Talc; Hypromellose 2910 (15000 mpa.s); Microcrystalline cellulose
|
|||||
| Dosage Form | 8 HR Extended Release Oral Tablet | |||||
| Company | Alvogen | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Magnesium stearate; Talc; Hypromellose 2208 (15000 mpa.s); Microcrystalline cellulose
|
|||||
| Dosage Form | 8 HR Extended Release Oral Tablet | |||||
| Company | County Line Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Cellulose, microcrystalline; Fd&c green no. 3
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Unither Manufacturing | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Fd&c green no. 3; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Upstate Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Methylphenidate 5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 17 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Sucrose; Silicon dioxide
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Sucrose; Silicon dioxide; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Talc; Polyethylene glycol 8000
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Anhydrous citric acid; Lactose monohydrate; Magnesium stearate; Silicon dioxide
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Nostrum Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Kyselina citronova | DIG Info | Perilipin-1 (IC50 = 3708 nM) | [15] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Stearic acid; Maltose; Aspartame; Phosphoric acid; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Chewable Tablet | |||||
| Company | GAVIS Pharmaceuticals; Novel Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [2] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose; D&c yellow no. 10; Magnesium stearate; Sucrose; Talc; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Novartis Pharmaceuticals Corporation; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Talc; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lupin Pharmaceuticals; Novel Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Talc; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | KVK Tech | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Sucrose; Cellulose, microcrystalline; Colloidal silicon dioxide
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Camber Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Stearic acid; Maltose; Aspartame; Cellulose, microcrystalline; Guar gum; Starch, corn
|
|||||
| Dosage Form | Chewable Tablet | |||||
| Company | Shionogi | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [2] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Fd&c yellow no. 6; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | CorePharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose; D&c yellow no. 10; Magnesium stearate; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Unither Manufacturing | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose, unspecified form; D&c yellow no. 10; Magnesium stearate; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Upstate Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging; Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Mallinckrodt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Alvogen | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Methylphenidate 20 mg tablet | Click to Show/Hide the Full List of Formulation(s): 26 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Sucrose; Silicon dioxide; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Sucrose; Silicon dioxide
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Actavis Pharma; Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Anhydrous citric acid; Lactose monohydrate; Magnesium stearate; Silicon dioxide
|
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| Dosage Form | Oral Tablet | |||||
| Company | Nostrum Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Kyselina citronova | DIG Info | Perilipin-1 (IC50 = 3708 nM) | [15] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose; D&c yellow no. 10; Magnesium stearate; Sucrose; Talc; Polyethylene glycols; Tragacanth
|
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| Dosage Form | Oral Tablet | |||||
| Company | Novartis Pharmaceuticals Corporation; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Sucrose; Talc; Polyethylene glycol; Tragacanth
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose, unspecified form; D&c yellow no. 10; Magnesium stearate; Sucrose; Talc; Polyethylene glycol, unspecified; Tragacanth
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Talc; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lupin Pharmaceuticals; Novel Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Talc; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | KVK Tech | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Sucrose; Cellulose, microcrystalline; Colloidal silicon dioxide
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Camber Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Talc; Polyethylene glycol 8000
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Anhydrous lactose; Cetyl alcohol; Magnesium stearate; Ethylcellulose
|
|||||
| Dosage Form | 8 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [16] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Anhydrous lactose; Cetyl alcohol; Magnesium stearate; Ethylcellulose, unspecified
|
|||||
| Dosage Form | 8 HR Extended Release Oral Tablet | |||||
| Company | Upstate Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [16] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Anhydrous lactose; Cetyl alcohol; Magnesium stearate; Ethylcelluloses
|
|||||
| Dosage Form | 8 HR Extended Release Oral Tablet | |||||
| Company | Unither Manufacturing | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [16] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Fd&c yellow no. 6; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | CorePharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose; Fd&c yellow no. 6; Magnesium stearate; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Unither Manufacturing | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose, unspecified form; Fd&c yellow no. 6; Magnesium stearate; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Upstate Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose; Cetostearyl alcohol; Magnesium stearate; Titanium dioxide; Methyl alcohol; Mineral oil; Povidones; Zein
|
|||||
| Dosage Form | 8 HR Extended Release Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging; Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Mallinckrodt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Alvogen | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Magnesium stearate; Talc; Cellulose, microcrystalline; Hypromellose 2208 (15000 mpa.s)
|
|||||
| Dosage Form | 8 HR Extended Release Oral Tablet | |||||
| Company | Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Magnesium stearate; Talc; Hypromellose 2208 (15000 mpa.s); Microcrystalline cellulose
|
|||||
| Dosage Form | 8 HR Extended Release Oral Tablet | |||||
| Company | Mallinckrodt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Magnesium stearate; Talc; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | 8 HR Extended Release Oral Tablet | |||||
| Company | KVK Tech | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Magnesium stearate; Talc; Hypromellose 2208 (15000 mpa.s); Microcrystalline cellulose
|
|||||
| Dosage Form | 8 HR Extended Release Oral Tablet | |||||
| Company | County Line Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Magnesium stearate; Talc; Hypromellose 2208 (15000 mpa.s); Microcrystalline cellulose
|
|||||
| Dosage Form | 8 HR Extended Release Oral Tablet | |||||
| Company | Alvogen | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [7] | |||
| Methylphenidate 2.5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 2 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Stearic acid; Maltose; Aspartame; Phosphoric acid; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Chewable Tablet | |||||
| Company | GAVIS Pharmaceuticals; Novel Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Phosphoric acid | DIG Info | Carbonic anhydrase IV (Ki = 9800 nM) | [9] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [2] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Stearic acid; Maltose; Aspartame; Cellulose, microcrystalline; Guar gum; Starch, corn
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| Dosage Form | Chewable Tablet | |||||
| Company | Shionogi | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [2] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [2] | |||
| Methylphenidate 30 mg capsule | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
click to show the detail info of this DFM
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 28; Fd&c blue no. 1; Acetone; Acetyltributyl citrate; Ferrosoferric oxide; Potassium hydroxide; Sucrose; Talc; Titanium dioxide; Water; Cellulose acetate; Gelatin; Hypromellose acetate succinate 12070923 (3 mm2/s); Hypromelloses; Shellac; Starch, corn
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Actavis Pharma; Actavis South Atlantic | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Methylphenidate 40 mg capsule | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
click to show the detail info of this DFM
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 28; Fd&c blue no. 1; Acetone; Acetyltributyl citrate; Ferrosoferric oxide; Potassium hydroxide; Sucrose; Talc; Titanium dioxide; Water; Cellulose acetate; Gelatin; Hypromellose acetate succinate 12070923 (3 mm2/s); Hypromelloses; Shellac; Starch, corn
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Actavis Pharma; Actavis South Atlantic | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Methylphenidate 20 mg capsule | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
click to show the detail info of this DFM
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Acetone; Acetyltributyl citrate; Ferrosoferric oxide; Potassium hydroxide; Sucrose; Talc; Titanium dioxide; Water; Cellulose acetate; Gelatin; Hypromellose acetate succinate 12070923 (3 mm2/s); Hypromelloses; Shellac; Starch, corn
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| Dosage Form | 24 HR Extended Release Oral Capsule | |||||
| Company | Actavis Pharma; Actavis South Atlantic; American Health Packaging | |||||
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