Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00489) | |||||
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| Name |
Omeprazole
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| Synonyms |
Click to Show/Hide the Synonyms of This API
omeprazole; 73590-58-6; Prilosec; Esomeprazole; Omeprazon; Audazol; Omapren; Omepral; Parizac; Zegerid; Mopral; Belmazol; Ceprandal; Dizprazol; Dudencer; Emeproton; Epirazole; Gastrimut; Gastroloc; Gibancer; Indurgan; Inhibitron; Inhipump; Logastric; Pepticum; Peptilcer; Prazidec; Sanamidol; Secrepina; Ulcometion; Mepral; Miracid; Omeprol; Omezol; Omisec; Omizac; Ompanyt; Ozoken; Prysma; Ramezol; Ulceral; Ulcesep; Ulcozol; Zefxon; Zoltum; Demeprazol; Nopramin; Omeprazol; Omezolan; Paprazol; Pepticus; Prazentol; Prazolit; Procelac; Regulacid; Danlox; Erbolin; Lensor; Morecon; Nilsec; Olexin; Omegast; Omesek; Ortanol; Osiren; Proclor; Result; Ulcsep; Victrix; Zepral; Omebeta 20; Tedec Ulceral; AULCER; Antra MUPS; Omerprazole; Omepradex; Omeprazolum; Prilosec OTC; Nexium IV; H 168/68; Gastrogard; Nuclosina; 119141-88-7; Esomperazole; MFCD00083192; Prestwick_808; C17H19N3O3S; CHEBI:77260; Esomeprazole sodium salt; 5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole; Aisi'aomeilazuona Esomeprazole Sodium; H-168/68; CHEMBL1503; Nexiam; MLS000069373; (S)-Esomeprazole; 73590-58-6 (free form); Omeprazole, 98+%; Omeprazol [INN-Spanish]; Omeprazolum [INN-Latin]; NCGC00016925-06; SMR000058847; Emilok; CAS-73590-58-6; DSSTox_CID_1080; (s)-omeprazole sodium; DSSTox_RID_75929; DSSTox_GSID_21080; ( -)-Omeprazole; Omeprazone; Omeprazen; Omesec; Omeprazole delayed-release; Omeprazole Pellets; 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]-1H-benzimidazole; 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]benzimidazole; Prilosec (TN); (+-)-Omeprazole; CCRIS 7099; HSDB 3575; SR-01000003003; Omperazole; 161796-78-7; Omeprazole, solid; AGI-010; Omeprazole,(S); Omeprazole solution; DM-3458; Omeprazole [USAN:USP:INN:BAN:JAN]; Omeprazole (Prilosec); ACMC-20p1du; Maybridge4_002645; Opera_ID_1863; Prestwick0_000493; Prestwick1_000493; Prestwick2_000493; Prestwick3_000493; (.+/-.)-Omeprazole; UPCMLD-DP075; 5-Methoxy-2[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]-1H-benzimidazole; cid_4594; SCHEMBL1191; BSPBio_000385; MLS001076112; MLS001424148; MLS006010400; MLS006011759; BIDD:GT0189; SPBio_002306; BPBio1_000425; GTPL4279; Omeprazole (JP17/USP/INN); Esomeprazole sodium salt hydrate; DTXSID6021080; SCHEMBL11995456; UPCMLD-DP075:001; CHEBI:91766; HMS1528I05; HMS1569D07; HMS2052G17; HMS2090E16; HMS2090F11; HMS2096D07; HMS2232B21; HMS3269D17; HMS3394G17; HMS3413J07; HMS3651A11; HMS3677J07; HMS3713D07; Pharmakon1600-01505693; (S)-Omeprazole sodium salt hydrate; BCP05852; BCP13592; BCP21299; HY-B0113; 2,3,5-Trimethylpyridine/Omeprazole; Tox21_110686; Tox21_200509; AC-401; BBL028172; BDBM50103597; BDBM50241343; CO0037; DL-462; NSC751450; NSC759192; STK623746; 119141-88-7 (base); AKOS005066653; AKOS015895343; Tox21_110686_1; AC-4676; CCG-101130; CCG-213517; CS-1868; DB00338; HS-0055; MCULE-3224208952; NC00380; NE55490; NSC-751450; NSC-759192; IDI1_032523; NCGC00016925-01; NCGC00016925-02; NCGC00016925-03; NCGC00016925-04; NCGC00016925-05; NCGC00016925-07; NCGC00016925-08; NCGC00016925-10; NCGC00016925-11; NCGC00021522-03; NCGC00021522-04; NCGC00021522-05; NCGC00258063-01; Omeprazole, analytical reference material; AK162396; SY077145; SBI-0206896.P001; AB0014122; FT-0601585; FT-0652860; FT-0653294; FT-0673283; FT-0689771; SW196942-4; A19447; C07324; D00455; J10125; 668985-31-7 (Mg); 141O887; A837865; Q422210; SR-01000003003-4; SR-01000003003-7; SR-01000003003-8; 5-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2-yl); BRD-A55962179-001-04-9; BRD-A55962179-001-08-0; BRD-A55962179-001-20-5; BRD-A88691025-001-07-4; F0001-2386; Z1672902589; Omeprazole, British Pharmacopoeia (BP) Reference Standard; Omeprazole, European Pharmacopoeia (EP) Reference Standard; Omeprazole, United States Pharmacopeia (USP) Reference Standard; 2-(3-methoxy-2,4-dimethylbenzylsulfinyl)-6-methoxy-1H-benzo[d]imidazole; 5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2- pyridinyl)methyl)sulfinyl)-; Omeprazole, Pharmaceutical Secondary Standard; Certified Reference Material; (RS)-5-Methoxy-2-(4-methoxy-3,5-dimethyl-2-pyridylmethylsulphinyl)benzimidazole; 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl- 1H-benzimidazole; 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-benzimidazole
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| Clinical Status |
Approved
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| Disease Indication | Gastro-oesophageal reflux disease | ICD-11: DA22 | [1] | ||
| PubChem CID | |||||
| Formula |
C17H19N3O3S
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| Canonical SMILES |
CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC
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| InChI |
1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)
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| InChIKey |
SUBDBMMJDZJVOS-UHFFFAOYSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=4594"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 345.4 | Topological Polar Surface Area | 96.3 | |
| XlogP | 2.2 | Complexity | 453 | ||
| Heavy Atom Count | 24 | Rotatable Bond Count | 5 | ||
| Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 6 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
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| Omeprazole 10 mg capsule | Click to Show/Hide the Full List of Formulation(s): 24 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Povidone; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Poloxamer 124
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Povidone; Silicon dioxide; Alcohol; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Poloxamer 124; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Poloxamer 407; Povidone; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Poloxamer 407; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Aidarex Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 5 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Triethyl citrate; Poloxamer 407; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 6 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Triethyl citrate; Poloxamer 407; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 7 |
DFM Info
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Sodium stearate; Sucrose 1,6-distearate; Anhydrous lactose; Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Monoethanolamine lauryl sulfate; Sodium stearyl fumarate; Cetyl alcohol; Fd&c blue no. 2; Propylene glycol 1,2-distearate; Ammonia n-13; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Triethyl citrate; Gelatin hydrolysate (porcine skin, mw 3000); Carnauba wax; Fd&c green no. 3; Hypromellose phthalate (31% phthalate, 40 cst); Hypromelloses; Povidone k90; Shellac; Sodium phosphate, dibasic, anhydrous
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearate | DIG Info | Free fatty acid receptor 4 (EC50 = 1698.24 nM) | [12] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Monoethanolamine lauryl sulfate | DIG Info | Noradrenaline N-methyltransferase (IC50 = 109000 nM) | [17] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| Gelatin | DIG Info | Mephenytoin 4-hydroxylase (EC50 = 20.5 uM) | [7] | |||
| Drug Formulation 8 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Cetyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Mannitol; Sodium phosphate, dibasic, dihydrate; Titanium dioxide; Fd&c red no. 3; Gelatin; Hypromellose phthalate (31% phthalate, 40 cst); Hypromelloses
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Drug Formulation 9 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Cetyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Mannitol; Titanium dioxide; Fd&c red no. 3; Gelatin; Hypromellose phthalate (31% phthalate, 40 cst); Hypromelloses; Sodium phosphate, dibasic dihydrate
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Drug Formulation 10 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Glyceryl monostearate; Meglumine; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Poloxamer 407; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Raw sugar; Shellac
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Drug Formulation 11 |
DFM Info
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Anhydrous lactose; D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; D&c red no. 7; Fd&c blue no. 1; Fd&c blue no. 2; Mannitol; Ferrosoferric oxide; Titanium dioxide; Gelatin; Hydroxypropyl cellulose (type h); Hypromelloses
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | AstraZeneca | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Drug Formulation 12 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Cetyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Mannitol; Sodium phosphate, dibasic, dihydrate; Titanium dioxide; Gelatin, unspecified; Hypromellose phthalate (31% phthalate, 40 cst); Hypromellose, unspecified
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| Drug Formulation 13 |
DFM Info
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Oleic acid; Sodium lauryl sulfate; Butyl alcohol; Dibutyl sebacate; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Silicon dioxide; Alcohol; Ethylcellulose (20 mpa.s); Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Breckenridge Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [20] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 14 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Glyceryl monostearate; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sodium phosphate, dibasic, dihydrate; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Gelatin, unspecified; Hydroxypropyl cellulose (type h); Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 15 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Glyceryl monostearate; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Cellulose, microcrystalline; Gelatin; Hydroxypropyl cellulose (type h); Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Sodium phosphate, dibasic dihydrate
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Aurobindo Pharma; Citron Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 16 |
DFM Info
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Oleic acid; Sodium lauryl sulfate; D&c yellow no. 10; Dibutyl sebacate; Ammonia; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Ethylcellulose, unspecified; Fd&c green no. 3; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [20] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 17 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Butyl alcohol; Glyceryl behenate; Isopropyl alcohol; Aluminum chlorohydrex propylene glycol; Ammonia; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Silicon dioxide; Alcohol; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Kaiser Foundation Hospitals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 18 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Butyl alcohol; Glyceryl dibehenate; Isopropyl alcohol; Aluminum chlorohydrex propylene glycol; Ammonia; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Silicon dioxide; Alcohol; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | American Health Packaging; Kremers Urban Pharmaceuticals Inc.; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 19 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Glyceryl behenate; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Hypromellose; Silicon dioxide; Gelatin; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 20 |
DFM Info
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Butyl alcohol; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Magnesium hydroxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Povidone k30; Alcohol; Gelatin; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Apotex; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 21 |
DFM Info
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Anhydrous lactose; Dibutyl sebacate; Potassium chloride; Acetone; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Alcohol; Carrageenan; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Hypromellose 2208 (100 mpa.s); Hypromellose phthalate (24% phthalate, 55 cst); Povidones
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [21] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Drug Formulation 22 |
DFM Info
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Sodium lauryl sulfate; Fd&c blue no. 1; Acetone; Sodium phosphate, dibasic, dihydrate; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Fd&c red no. 3; Fd&c green no. 3; Gelatin; Hydroxypropyl cellulose (type h); Hypromellose phthalate (31% phthalate, 170 cst); Hypromelloses; Polyethylene glycols
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Drug Formulation 23 |
DFM Info
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Sodium lauryl sulfate; Fd&c blue no. 1; Acetone; Sodium phosphate, dibasic, dihydrate; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Fd&c red no. 3; Fd&c green no. 3; Gelatin; Hydroxypropyl cellulose; Hypromellose phthalate (31% phthalate, 170 cst); Hypromelloses; Polyethylene glycols
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Drug Formulation 24 |
DFM Info
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Anhydrous lactose; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Magnesium oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Gelatin, unspecified; Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Povidone k25; Shellac
|
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Omeprazole 20 mg capsule | Click to Show/Hide the Full List of Formulation(s): 62 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Povidone; Silicon dioxide; Alcohol; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Peg/ppg-30/160 copolymer; Shellac
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|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Legacy Pharmaceutical; Life Line Home Care Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Povidone; Silicon dioxide; Alcohol; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Poloxamer 181; Shellac
|
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Medsource Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
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|
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Povidone; Silicon dioxide; Alcohol; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Poloxamer 124; Shellac
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Silicon dioxide; Alcohol; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Poloxamer 182; Povidones; Shellac
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 5 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Povidone; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Poloxamer 124
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 6 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Poloxamer 407; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 7 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Poloxamer 407; Povidone; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Dr Reddy's Laboratories; Midwest Drug Distribution; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 8 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Poloxamer 407; Povidone; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 9 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Poloxamer 407; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Shellac
|
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | A-S Medication Solutions; Aidarex Pharmaceuticals; RemedyRepack; TYA Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 10 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Poloxamer 407; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Legacy Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 11 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Triethyl citrate; Poloxamer 407; Povidone; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 12 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Triethyl citrate; Poloxamer 407; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Shellac
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Clinical Solutions Wholesale; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 13 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Triethyl citrate; Poloxamer 407; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified; Shellac
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 14 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Poloxamer 407; Colloidal silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 15 |
DFM Info
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Sodium stearate; Lactose monohydrate; Sodium lauryl sulfate; Carminic acid; Menthol, unspecified form; Sodium stearyl fumarate; Sucralose; Benzyl alcohol; Fd&c blue no. 2; Monoethanolamine; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Polyethylene glycol 3350; Carnauba wax; Hypromelloses
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | CVS Pharmacy; Kroger Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [9] | |||
| Hydroxyethylamine | DIG Info | Lipid transfer protein I (IC50 = 600 nM) | [10] | |||
| Benzyl alcohol | DIG Info | Indoleamine 2,3-dioxygenase 1 (IC50 = 1400 nM) | [11] | |||
| Sodium stearate | DIG Info | Free fatty acid receptor 4 (EC50 = 1698.24 nM) | [12] | |||
| Menthol | DIG Info | Transient receptor potential p8 (EC50 = 3000 nM) | [13] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Carminic acid | DIG Info | Protein-tyrosine phosphatase 1B (IC50 = 15000 nM) | [14] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Drug Formulation 16 |
DFM Info
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Sodium stearate; Lactose monohydrate; Sodium lauryl sulfate; Menthol; Sodium stearyl fumarate; Sucralose; Benzyl alcohol; Monoethanolamine; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Polyethylene glycol 3350; Carnauba wax; Hypromelloses
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | H E B; Meijer; Shopko | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [9] | |||
| Hydroxyethylamine | DIG Info | Lipid transfer protein I (IC50 = 600 nM) | [10] | |||
| Benzyl alcohol | DIG Info | Indoleamine 2,3-dioxygenase 1 (IC50 = 1400 nM) | [11] | |||
| Sodium stearate | DIG Info | Free fatty acid receptor 4 (EC50 = 1698.24 nM) | [12] | |||
| Menthol | DIG Info | Transient receptor potential p8 (EC50 = 3000 nM) | [13] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Drug Formulation 17 |
DFM Info
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Sodium stearate; Lactose monohydrate; Sodium lauryl sulfate; Menthol, unspecified form; Sodium stearyl fumarate; Sucralose; Benzyl alcohol; Monoethanolamine; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Polyethylene glycol 3350; Carnauba wax; Hypromelloses
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Rite Aid; Topco Associates | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [9] | |||
| Hydroxyethylamine | DIG Info | Lipid transfer protein I (IC50 = 600 nM) | [10] | |||
| Benzyl alcohol | DIG Info | Indoleamine 2,3-dioxygenase 1 (IC50 = 1400 nM) | [11] | |||
| Sodium stearate | DIG Info | Free fatty acid receptor 4 (EC50 = 1698.24 nM) | [12] | |||
| Menthol | DIG Info | Transient receptor potential p8 (EC50 = 3000 nM) | [13] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Drug Formulation 18 |
DFM Info
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Sodium lauryl sulfate; Glyceryl monostearate; Magnesium stearate; Anhydrous dibasic calcium phosphate; Ferric oxide red; Ferrosoferric oxide; Magnesium oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Hypromellose 2208 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methacrylic acid - methyl methacrylate copolymer (1:2); Raw sugar; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Albertsons Companies; CVS Pharmacy; Cardinal Health; Chain Drug Consortium; Chain Drug Marketing Association; Family Dollar; Fred's; H-E-B; Kaiser Permanente; Kroger; Meijer; Target Corporation; Wal-Mart Stores; Walgreens Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 19 |
DFM Info
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Sodium lauryl sulfate; Glyceryl monostearate; Magnesium stearate; Anhydrous dibasic calcium phosphate; Ferric oxide red; Magnesium oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Silicon dioxide; Carrageenan; Hypromellose 2208 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methacrylic acid - methyl methacrylate copolymer (1:2); Microcrystalline cellulose; Raw sugar; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Reliable 1 Laboratires | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 20 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Glyceryl monostearate; Meglumine; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Poloxamer 407; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Raw sugar; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Drug Formulation 21 |
DFM Info
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Anhydrous lactose; D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; D&c red no. 7; Fd&c blue no. 1; Fd&c blue no. 2; Mannitol; Ferrosoferric oxide; Titanium dioxide; Gelatin; Hydroxypropyl cellulose (type h); Hypromelloses
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | AstraZeneca | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Drug Formulation 22 |
DFM Info
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Oleic acid; Sodium lauryl sulfate; Butyl alcohol; Dibutyl sebacate; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Silicon dioxide; Alcohol; Ethylcellulose (20 mpa.s); Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Breckenridge Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [20] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 23 |
DFM Info
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Glyceryl monostearate; Magnesium stearate; Potassium chloride; Anhydrous dibasic calcium phosphate; Ferric oxide red; Ferrosoferric oxide; Magnesium oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Carrageenan; Cellulose, microcrystalline; Hypromellose 2208 (3 mpa.s); Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methacrylic acid - methyl methacrylate copolymer (1:2); Raw sugar; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [21] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 24 |
DFM Info
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Sodium lauryl sulfate; Glyceryl monostearate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Magnesium oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Silicon dioxide; Calcium phosphate, dibasic, anhydrous; Cellulose, microcrystalline; Gelatin; Hypromellose 2208 (3 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methacrylic acid - methyl methacrylate copolymer (1:2); Raw sugar; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Gericare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 25 |
DFM Info
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Oleic acid; Sodium lauryl sulfate; D&c yellow no. 10; Dibutyl sebacate; Ammonia; Talc; Titanium dioxide; Triethyl citrate; Hypromellose; Silicon dioxide; Silicon dioxide; Ethylcellulose; Fd&c green no. 3; Gelatin; Methacrylic acid
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [20] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 26 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Glyceryl monostearate; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sodium phosphate, dibasic, dihydrate; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Gelatin, unspecified; Hydroxypropyl cellulose (type h); Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 27 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Glyceryl monostearate; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sodium phosphate, dibasic, dihydrate; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Cellulose, microcrystalline; Gelatin; Hydroxypropyl cellulose (type h); Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 28 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Glyceryl monostearate; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Cellulose, microcrystalline; Gelatin; Hydroxypropyl cellulose (type h); Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Sodium phosphate, dibasic
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 29 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Glyceryl monostearate; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Cellulose, microcrystalline; Gelatin; Hydroxypropyl cellulose (type h); Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Sodium phosphate, dibasic dihydrate
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Aurobindo Pharma; Citron Pharma; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Sodium stearate; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Monoethanolamine; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Carnauba wax; Hypromelloses
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Gericare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydroxyethylamine | DIG Info | Lipid transfer protein I (IC50 = 600 nM) | [10] | |||
| Sodium stearate | DIG Info | Free fatty acid receptor 4 (EC50 = 1698.24 nM) | [12] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Oleic acid; Sodium lauryl sulfate; D&c yellow no. 10; Dibutyl sebacate; Ammonia; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Ethylcellulose, unspecified; Fd&c green no. 3; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid; Shellac; Starch, corn
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Bryant Ranch Prepack; Golden State Medical Supply; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [20] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Oleic acid; Sodium lauryl sulfate; D&c yellow no. 10; Dibutyl sebacate; Ammonia; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Ethylcelluloses; Fd&c green no. 3; Gelatin; Hypromelloses; Methacrylic acid; Shellac; Starch, corn
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Blenheim Phamacal; Dispensing Solution | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [20] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Oleic acid; Sodium lauryl sulfate; D&c yellow no. 10; Dibutyl sebacate; Ammonia; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Silicon dioxide; Ethylcelluloses; Fd&c green no. 3; Gelatin; Hypromelloses; Methacrylic acid; Starch, corn
|
|||||
| Dosage Form | Delayed Release Capsule | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [20] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Cetyl alcohol; Fd&c blue no. 2; Ammonia; Propylene glycol; Sucrose; Talc; Titanium dioxide; Fd&c green no. 3; Gelatin; Hypromellose phthalate (31% phthalate, 40 cst); Povidone k90; Shellac; Sodium phosphate, dibasic, anhydrous
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Raritan Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 35 |
DFM Info
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|||||
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Oleic acid; Sodium lauryl sulfate; D&c yellow no. 10; Dibutyl sebacate; Ammonia; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Silicon dioxide; Ethylcelluloses; Fd&c green no. 3; Gelatin; Hypromelloses; Methacrylic acid
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | H. J. Harkins Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [20] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 36 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Cetyl alcohol; Fd&c blue no. 1; Mannitol; Sodium phosphate, dibasic, dihydrate; Titanium dioxide; Fd&c red no. 3; Gelatin, unspecified; Hypromellose phthalate (31% phthalate, 40 cst); Hypromellose, unspecified
|
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Cetyl alcohol; Fd&c blue no. 1; Mannitol; Sodium phosphate, dibasic, dihydrate; Titanium dioxide; Fd&c red no. 3; Gelatin; Hypromellose phthalate (31% phthalate, 40 cst); Hypromelloses
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | A-S Medication Solutions; Blenheim Phamacal; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Drug Formulation 38 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Cetyl alcohol; Fd&c blue no. 1; Mannitol; Titanium dioxide; Fd&c red no. 3; Gelatin, unspecified; Hypromellose phthalate (31% phthalate, 40 cst); Hypromellose, unspecified; Sodium phosphate, dibasic dihydrate
|
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Drug Formulation 39 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Cetyl alcohol; Fd&c blue no. 1; Mannitol; Titanium dioxide; Fd&c red no. 3; Gelatin; Hypromellose phthalate (31% phthalate, 40 cst); Hypromelloses; Sodium phosphate, dibasic dihydrate
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Glenmark Pharmaceutials; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Drug Formulation 40 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Butyl alcohol; Glyceryl dibehenate; Isopropyl alcohol; Aluminum chlorohydrex propylene glycol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Silicon dioxide; Alcohol; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
|
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Aphena Pharma Solutions-Tennessee; AvPAK; Kremers Urban Pharmaceuticals Inc.; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 41 |
DFM Info
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|||||
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Butyl alcohol; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Magnesium hydroxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Povidone; Alcohol; Gelatin; Shellac
|
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Department Of Health Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Drug Formulation 42 |
DFM Info
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|||||
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Butyl alcohol; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Magnesium hydroxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Povidone; Alcohol; Gelatin; Shellac
|
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Drug Formulation 43 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Glyceryl behenate; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Hypromellose; Silicon dioxide; Gelatin; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
|
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Altura Pharmaceuticals; Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 44 |
DFM Info
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|||||
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Oleic acid; Sodium lauryl sulfate; D&c yellow no. 10; Dibutyl sebacate; Ammonia; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Ethylcellulose, unspecified; Fd&c green no. 3; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [20] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 45 |
DFM Info
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|||||
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Oleic acid; Sodium lauryl sulfate; D&c yellow no. 10; Dibutyl sebacate; Ammonia; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Ethylcelluloses; Fd&c green no. 3; Gelatin; Hypromelloses; Methacrylic acid
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [20] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 46 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Cetyl alcohol; Fd&c blue no. 1; Mannitol; Sodium phosphate, dibasic, dihydrate; Titanium dioxide; Gelatin, unspecified; Hypromellose phthalate (31% phthalate, 40 cst); Hypromellose, unspecified
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Glenmark Pharmaceutials; NuCare Pharmaceuticals; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| Drug Formulation 47 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Cetyl alcohol; Fd&c blue no. 1; Mannitol; Sodium phosphate, dibasic, dihydrate; Titanium dioxide; Gelatin, unspecified; Hypromellose phthalate (31% phthalate, 40 cst); Hypromellose, unspecified
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Mas Management Group | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| Drug Formulation 48 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Cetyl alcohol; Fd&c blue no. 1; Mannitol; Titanium dioxide; Gelatin; Hypromellose phthalate (31% phthalate, 40 cst); Hypromelloses; Sodium phosphate, dibasic dihydrate
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Preferred Pharamaceuticals; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| Drug Formulation 49 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Butyl alcohol; Glyceryl dibehenate; Isopropyl alcohol; Aluminum chlorohydrex propylene glycol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Alcohol; Crospovidone (15 mpa.s at 5%); Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 50 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Butyl alcohol; Glyceryl dibehenate; Isopropyl alcohol; Aluminum chlorohydrex propylene glycol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Alcohol; Crospovidone, unspecified; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 51 |
DFM Info
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|||||
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Butyl alcohol; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Magnesium hydroxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Povidone k30; Alcohol; Gelatin; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 52 |
DFM Info
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|||||
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Butyl alcohol; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Magnesium hydroxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Povidone k30; Alcohol; Gelatin; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Apotex; Blenheim Phamacal; Cardinal Health; Carilion Materials Management; Contract Pharmacal; DirectRX; Major Pharmaceuticals; New Horizon Rx Group; Northwind Pharmaceuticals; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; Preferred Pharamaceuticals; Proficient Rx; RemedyRepack; RxChange; Safecor Health; St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 53 |
DFM Info
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Butyl alcohol; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Magnesium hydroxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Povidone k30; Alcohol; Gelatin, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 54 |
DFM Info
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Butyl alcohol; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Magnesium hydroxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Alcohol; Gelatin, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 55 |
DFM Info
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Anhydrous lactose; Dibutyl sebacate; Potassium chloride; Acetone; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Alcohol; Carrageenan; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose 2208 (100 mpa.s); Hypromellose phthalate (24% phthalate, 55 cst); Povidones
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [21] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Drug Formulation 56 |
DFM Info
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Anhydrous lactose; Dibutyl sebacate; Potassium chloride; Acetone; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Alcohol; Carrageenan; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Hypromellose 2208 (100 mpa.s); Hypromellose phthalate (24% phthalate, 55 cst); Povidones
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | McKesson; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [21] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Drug Formulation 57 |
DFM Info
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Sodium lauryl sulfate; Fd&c blue no. 1; Acetone; Ferric oxide red; Ferric oxide yellow; Sodium phosphate, dibasic, dihydrate; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Gelatin; Hydroxypropyl cellulose (type h); Hypromellose phthalate (31% phthalate, 170 cst); Hypromelloses; Polyethylene glycols
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Drug Formulation 58 |
DFM Info
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Sodium lauryl sulfate; Fd&c blue no. 1; Acetone; Ferric oxide red; Ferric oxide yellow; Sodium phosphate, dibasic, dihydrate; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Gelatin; Hydroxypropyl cellulose; Hypromellose phthalate (31% phthalate, 170 cst); Hypromelloses; Polyethylene glycols
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Drug Formulation 59 |
DFM Info
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Fd&c blue no. 2
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 60 |
DFM Info
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Anhydrous lactose; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Magnesium oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Povidone; Cellulose, microcrystalline; Gelatin; Hydroxypropyl cellulose, low substituted; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 61 |
DFM Info
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Anhydrous lactose; Magnesium stearate; Ferrosoferric oxide; Magnesium oxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Gelatin, unspecified; Low-substituted hydroxypropyl cellulose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Povidone k25; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | RemedyRepack; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 62 |
DFM Info
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Anhydrous lactose; Dibutyl sebacate; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Povidone; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Hypromellose phthalate (31% phthalate, 40 cst); Hypromelloses
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Omeprazole 40 mg capsule | Click to Show/Hide the Full List of Formulation(s): 40 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Povidone; Silicon dioxide; Alcohol; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Peg/ppg-30/160 copolymer; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Silicon dioxide; Alcohol; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Poloxamer 182; Povidones; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Povidone; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Poloxamer 124
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 4 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Poloxamer 407; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 5 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Poloxamer 407; Povidone; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Dr Reddy's Laboratories; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 6 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Poloxamer 407; Povidone; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 7 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Poloxamer 407; Povidone; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 8 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Triethyl citrate; Crospovidone; Poloxamer 407; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidones; Shellac
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Aidarex Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 9 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Meglumine; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Triethyl citrate; Poloxamer 407; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Povidone, unspecified; Shellac
|
|||||
| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Bryant Ranch Prepack; Cardinal Health; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 10 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Cetyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Mannitol; Sodium phosphate, dibasic, dihydrate; Titanium dioxide; Fd&c red no. 3; Gelatin, unspecified; Hypromellose phthalate (31% phthalate, 40 cst); Hypromellose, unspecified
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Drug Formulation 11 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Cetyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Mannitol; Sodium phosphate, dibasic, dihydrate; Titanium dioxide; Fd&c red no. 3; Gelatin; Hypromellose phthalate (31% phthalate, 40 cst); Hypromelloses
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | A-S Medication Solutions; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Drug Formulation 12 |
DFM Info
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D&c red no. 28; Lactose; Sodium lauryl sulfate; D&c yellow no. 10; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Isopropyl alcohol; Mannitol; Titanium dioxide; Hypromellose; Cellulose, microcrystalline; Ferric oxide; Gelatin; Hydroxypropyl cellulose
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Ranbaxy Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Drug Formulation 13 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Cetyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Mannitol; Titanium dioxide; Fd&c red no. 3; Gelatin; Hypromellose phthalate (31% phthalate, 40 cst); Hypromelloses; Sodium phosphate, dibasic dihydrate
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Drug Formulation 14 |
DFM Info
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D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Glyceryl monostearate; Meglumine; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Poloxamer 407; Gelatin; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Raw sugar; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Dr Reddy's Laboratories; Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [7] | |||
| Drug Formulation 15 |
DFM Info
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Anhydrous lactose; D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; D&c red no. 7; Fd&c blue no. 1; Fd&c blue no. 2; Mannitol; Ferrosoferric oxide; Titanium dioxide; Gelatin; Hydroxypropyl cellulose (type h); Hypromelloses
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | AstraZeneca | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Cetyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Mannitol; Sodium phosphate, dibasic, dihydrate; Titanium dioxide; Gelatin, unspecified; Hypromellose phthalate (31% phthalate, 40 cst); Hypromellose, unspecified
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Glenmark Pharmaceutials; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| Drug Formulation 17 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Cetyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Mannitol; Sodium phosphate, dibasic, dihydrate; Titanium dioxide; Gelatin; Hypromellose phthalate (31% phthalate, 40 cst); Hypromelloses
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| Drug Formulation 18 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Cetyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Mannitol; Titanium dioxide; Gelatin, unspecified; Hypromellose phthalate (31% phthalate, 40 cst); Hypromellose, unspecified; Sodium phosphate, dibasic dihydrate
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| Drug Formulation 19 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Cetyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Mannitol; Titanium dioxide; Gelatin; Hypromellose phthalate (31% phthalate, 40 cst); Hypromelloses; Sodium phosphate, dibasic dihydrate
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | NuCare Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Oleic acid; Sodium lauryl sulfate; Butyl alcohol; Dibutyl sebacate; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Silicon dioxide; Alcohol; Ethylcellulose (20 mpa.s); Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Breckenridge Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [20] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 21 |
DFM Info
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Oleic acid; Sodium lauryl sulfate; D&c yellow no. 10; Dibutyl sebacate; Fd&c blue no. 1; Ammonia; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Ethylcellulose, unspecified; Fd&c green no. 3; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid; Shellac; Starch, corn
|
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Golden State Medical Supply; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [20] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 22 |
DFM Info
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Oleic acid; Sodium lauryl sulfate; D&c yellow no. 10; Dibutyl sebacate; Fd&c blue no. 1; Ammonia; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Ethylcelluloses; Fd&c green no. 3; Gelatin; Hypromelloses; Methacrylic acid; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Blenheim Phamacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [20] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 23 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Cetyl alcohol; Fd&c blue no. 2; Ammonia; Propylene glycol; Sodium phosphate, dibasic, dihydrate; Sucrose; Talc; Titanium dioxide; Povidone; Fd&c green no. 3; Gelatin; Hypromellose 2208 (15000 cps); Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Kaiser Foundation Hospitals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
| Drug Formulation 24 |
DFM Info
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Oleic acid; Sodium lauryl sulfate; D&c yellow no. 10; Dibutyl sebacate; Fd&c blue no. 1; Ammonia; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Silicon dioxide; Ethylcelluloses; Fd&c green no. 3; Gelatin; Hypromelloses; Methacrylic acid; Starch, corn
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| Dosage Form | Delayed Release Capsule | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Oleic acid | DIG Info | Liver lipid-binding protein (Ki = 180 nM) | [20] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 25 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Glyceryl monostearate; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sodium phosphate, dibasic, dihydrate; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Gelatin, unspecified; Hydroxypropyl cellulose (type h); Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 26 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Glyceryl monostearate; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Cellulose, microcrystalline; Gelatin; Hydroxypropyl cellulose (type h); Hypromellose 2910 (5 mpa.s); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Sodium phosphate, dibasic dihydrate
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Aurobindo Pharma; Citron Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Drug Formulation 27 |
DFM Info
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Sodium lauryl sulfate; Fd&c red no. 40; Fd&c blue no. 1; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Titanium dioxide; Triethyl citrate; Sodium phosphate, tribasic, dodecahydrate; Polyethylene glycol 6000; Povidone k30; Hypromellose 2910 (6 mpa.s); Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac; Starch, corn
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Golden State Medical Supply; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 28 |
DFM Info
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Sucrose 1,6-distearate; Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Cetyl alcohol; Fd&c blue no. 2; Propylene glycol 1,2-distearate; Ammonia n-13; Talc; Titanium dioxide; Gelatin hydrolysate (porcine skin, mw 3000); Fd&c green no. 3; Hypromellose phthalate (31% phthalate, 40 cst); Povidone k90; Shellac; Sodium phosphate, dibasic, anhydrous
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| Gelatin | DIG Info | Mephenytoin 4-hydroxylase (EC50 = 20.5 uM) | [7] | |||
| Drug Formulation 29 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Cetyl alcohol; Fd&c blue no. 2; Ammonia; Propylene glycol; Sucrose; Talc; Titanium dioxide; Fd&c green no. 3; Gelatin; Hypromellose phthalate (31% phthalate, 40 cst); Povidone k90; Shellac; Sodium phosphate, dibasic, anhydrous
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Actavis Pharma; Raritan Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 30 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Cetyl alcohol; Fd&c blue no. 2; Ammonia; Propylene glycol; Sucrose; Talc; Titanium dioxide; Fd&c green no. 3; Gelatin, unspecified; Hypromellose phthalate (31% phthalate, 40 cst); Povidone k90; Shellac; Sodium phosphate, dibasic, anhydrous
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
| Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [18] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 31 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Butyl alcohol; Glyceryl dibehenate; Isopropyl alcohol; Aluminum chlorohydrex propylene glycol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Silicon dioxide; Alcohol; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Aphena Pharma Solutions-Tennessee; AvPAK; Kremers Urban Pharmaceuticals Inc.; NuCare Pharmaceuticals; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 32 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Butyl alcohol; Glyceryl behenate; Isopropyl alcohol; Aluminum chlorohydrex propylene glycol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Crospovidone; Silicon dioxide; Alcohol; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 33 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Butyl alcohol; Glyceryl dibehenate; Isopropyl alcohol; Aluminum chlorohydrex propylene glycol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Alcohol; Crospovidone (15 mpa.s at 5%); Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 34 |
DFM Info
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Butyl alcohol; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Magnesium hydroxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Povidone k30; Alcohol; Gelatin; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Apotex; Avera McKennan Hospital; Blenheim Phamacal; DirectRX; Golden State Medical Supply; Lake Eire Medical & Surgical Supply DBA Quality Care Products; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; Preferred Pharamaceuticals; Proficient Rx; St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 35 |
DFM Info
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Butyl alcohol; Isopropyl alcohol; Mannitol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Magnesium hydroxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Triethyl citrate; Povidone k30; Alcohol; Gelatin, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Shellac
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [19] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 36 |
DFM Info
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Anhydrous lactose; Dibutyl sebacate; Potassium chloride; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Carrageenan; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Povidones
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [21] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Drug Formulation 37 |
DFM Info
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Anhydrous lactose; Dibutyl sebacate; Potassium chloride; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Carrageenan; Cellulose, microcrystalline; Hydroxypropyl cellulose, low substituted; Hypromellose 2208 (100 mpa.s); Hypromellose phthalate (24% phthalate, 55 cst); Povidones
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [21] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Drug Formulation 38 |
DFM Info
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Sodium lauryl sulfate; Fd&c blue no. 1; Acetone; Sodium phosphate, dibasic, dihydrate; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Fd&c red no. 3; Fd&c green no. 3; Gelatin; Hydroxypropyl cellulose (type h); Hypromellose phthalate (31% phthalate, 170 cst); Hypromelloses; Polyethylene glycols
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Drug Formulation 39 |
DFM Info
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Sodium lauryl sulfate; Fd&c blue no. 1; Acetone; Sodium phosphate, dibasic, dihydrate; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Fd&c red no. 3; Fd&c green no. 3; Gelatin; Hydroxypropyl cellulose; Hypromellose phthalate (31% phthalate, 170 cst); Hypromelloses; Polyethylene glycols
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Drug Formulation 40 |
DFM Info
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Sodium lauryl sulfate; Fd&c blue no. 1; Acetone; Sodium phosphate, dibasic, dihydrate; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Fd&c red no. 3; Fd&c green no. 3; Gelatin; Hydroxypropyl cellulose (type h); Hypromellose phthalate (31% phthalate, 170 cst); Hypromelloses; Polyethylene glycols
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| Dosage Form | Delayed Release Oral Capsule | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [2] | |||
| Omeprazole 20 mg tablet | Click to Show/Hide the Full List of Formulation(s): 13 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Sodium lauryl sulfate; Fd&c red no. 40; Sodium stearyl fumarate; Fd&c blue no. 1; Fd&c yellow no. 6; Glyceryl monostearate; Magnesium stearate; Meglumine; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | L. Perrigo Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Meglumine | DIG Info | Alglucerase (IC50 = 447000 nM) | [5] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Drug Formulation 2 |
DFM Info
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Sodium stearate; Lactose monohydrate; Sodium lauryl sulfate; Menthol; Sodium stearyl fumarate; Sucralose; Benzyl alcohol; Monoethanolamine; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Polyethylene glycol 3350; Carnauba wax; Hypromelloses
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Amerisource Bergen; Walgreens Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [9] | |||
| Hydroxyethylamine | DIG Info | Lipid transfer protein I (IC50 = 600 nM) | [10] | |||
| Benzyl alcohol | DIG Info | Indoleamine 2,3-dioxygenase 1 (IC50 = 1400 nM) | [11] | |||
| Sodium stearate | DIG Info | Free fatty acid receptor 4 (EC50 = 1698.24 nM) | [12] | |||
| Menthol | DIG Info | Transient receptor potential p8 (EC50 = 3000 nM) | [13] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [8] | |||
| Drug Formulation 3 |
DFM Info
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Fd&c red no. 40; Sodium stearyl fumarate; Fd&c blue no. 2; Glyceryl monostearate; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 6000; Polysorbate 80; Aluminum oxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Mica; Saccharin sodium
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Procter & Gamble Manufacturing Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Sodium stearate; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Monoethanolamine; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Carnauba wax; Hypromellose acetate succinate 12070923 (3 mm2/s); Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Chain Drug Marketing Association; Dexcel Pharma Technologies; Weeks & Leo | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydroxyethylamine | DIG Info | Lipid transfer protein I (IC50 = 600 nM) | [10] | |||
| Sodium stearate | DIG Info | Free fatty acid receptor 4 (EC50 = 1698.24 nM) | [12] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 5 |
DFM Info
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Sodium stearate; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Monoethanolamine; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Carnauba wax; Hypromelloses
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | SuperValu | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydroxyethylamine | DIG Info | Lipid transfer protein I (IC50 = 600 nM) | [10] | |||
| Sodium stearate | DIG Info | Free fatty acid receptor 4 (EC50 = 1698.24 nM) | [12] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 6 |
DFM Info
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Sodium stearate; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Monoethanolamine; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Carnauba wax; Hypromelloses
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | American Sales Company; Amerisource Bergen; Army & Air Force Exchange Service; BJWC; Big Lots Stores; CVS Pharmacy; Cardinal Health; DZA Brands; Dolgencorp; Family Dollar; Genomma Lab USA; H E B; Harmon Stores; Harris Teeter; Hy-Vee; Kinray; Kmart Corporation; Kroger Company; L. Perrigo Company; Lidl US; Major Pharmaceuticals; McKesson; Meijer; Perrigo New York; Publix Super Markets; RemedyRepack; Rite Aid; Safeway; Sam's West; Save-A-Lot Food Stores; Shopko; Target Corporation; Topco Associates; Wakefern Food Corporation; Wal-Mart Stores; Walgreens Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydroxyethylamine | DIG Info | Lipid transfer protein I (IC50 = 600 nM) | [10] | |||
| Sodium stearate | DIG Info | Free fatty acid receptor 4 (EC50 = 1698.24 nM) | [12] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Sodium stearate; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Monoethanolamine; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Carnauba wax; Hypromelloses
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | L. Perrigo Company; McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydroxyethylamine | DIG Info | Lipid transfer protein I (IC50 = 600 nM) | [10] | |||
| Sodium stearate | DIG Info | Free fatty acid receptor 4 (EC50 = 1698.24 nM) | [12] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Sodium stearate; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Monoethanolamine; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Carnauba wax; Hypromelloses
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Costco Wholesale | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydroxyethylamine | DIG Info | Lipid transfer protein I (IC50 = 600 nM) | [10] | |||
| Sodium stearate | DIG Info | Free fatty acid receptor 4 (EC50 = 1698.24 nM) | [12] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Sodium stearate; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Monoethanolamine; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Carnauba wax; Hypromelloses
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydroxyethylamine | DIG Info | Lipid transfer protein I (IC50 = 600 nM) | [10] | |||
| Sodium stearate | DIG Info | Free fatty acid receptor 4 (EC50 = 1698.24 nM) | [12] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Sodium stearate; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Monoethanolamine; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Carnauba wax; Hypromelloses
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydroxyethylamine | DIG Info | Lipid transfer protein I (IC50 = 600 nM) | [10] | |||
| Sodium stearate | DIG Info | Free fatty acid receptor 4 (EC50 = 1698.24 nM) | [12] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Sodium stearate; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Hypromellose; Carnauba wax; Ethanolamine; Hypromellose acetate succinate 12070923 (3 mm2/s); Sodium starch glycolate type a potato
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Dexcel Pharma Technologies; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearate | DIG Info | Free fatty acid receptor 4 (EC50 = 1698.24 nM) | [12] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
| Drug Formulation 12 |
DFM Info
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Sodium stearyl fumarate; Glyceryl monostearate; Magnesium stearate; Ferric oxide red; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 6000; Polysorbate 80; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Paraffin
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Physicians Total Care; Procter & Gamble Manufacturing Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [16] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [8] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Sodium stearate; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Triethyl citrate; Carnauba wax; Ethanolamine; Hypromellose acetate succinate 12070923 (3 mm2/s); Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Delayed Release Oral Tablet | |||||
| Company | Dexcel Pharma Technologies | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearate | DIG Info | Free fatty acid receptor 4 (EC50 = 1698.24 nM) | [12] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [15] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
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