Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00599) | |||||
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| Name |
Risperidone
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| Synonyms |
Click to Show/Hide the Synonyms of This API
risperidone; 106266-06-2; Risperidal; Risperdal; Rispolept; Risperdal Consta; Risperin; Rispolin; Sequinan; Apexidone; Risperidonum; Risperidona; Risperdal M-Tab; Belivon; Psychodal; Spiron; R 64 766; C23H27FN4O2; UNII-L6UH7ZF8HC; R 64766; R-64766; R 64,766; CHEMBL85; MFCD00274576; L6UH7ZF8HC; Risperidal M-Tab; CHEBI:8871; Risperidonum [Latin]; Risperidona [Spanish]; R-64-766; 106266-06-2 (free base); Risperidone, 99%; NCGC00015883-05; CAS-106266-06-2; DSSTox_CID_25193; DSSTox_RID_80740; DSSTox_GSID_45193; Zophrenal; Risperdal (TN); SMR000466323; SR-01000075399; BRN 4891881; Perseris; Relday; Rispen; Risperidone-ISM; HSDB 7580; Risperidone???; N05AX08; R64766; Risperidone [USAN:USP:INN:BAN]; Risperidone solution; R-64,766; KS-1106; Risperidone impurity K; Risperidone (Risperdal); Lopac-R-118; Prestwick0_001029; Prestwick1_001029; GTPL96; Risperidone(R 64 766); SCHEMBL27911; MLS000759429; MLS001165758; MLS001424081; US8802672, Risperidone; BIDD:GT0262; R 62 766; SPBio_003078; PYR332; Risperidone (JP17/USP/INN); DTXSID8045193; RCN3028; HMS1571M19; HMS2051H07; HMS2089C22; HMS2098M19; HMS2233O11; HMS3373M18; HMS3393H07; HMS3657G13; HMS3715M19; HMS3887G15; Pharmakon1600-01506038; ZINC538312; ACT04270; BCP08161; RCN-3028; Risperidone 1.0 mg/ml in Methanol; Tox21_110253; ANW-42874; BDBM50001885; CP-018; CR0023; NSC759895; NSC786035; NSC801188; STK646402; AKOS005577302; Tox21_110253_1; AC-1306; CCG-100930; CS-1619; DB00734; LY03004; MCULE-4027175053; NC00180; NSC-759895; NSC-786035; NSC-801188; PB26023; Risperidone, >=98% (HPLC), powder; NCGC00015883-01; NCGC00015883-02; NCGC00015883-03; NCGC00015883-04; NCGC00015883-06; NCGC00015883-07; NCGC00015883-08; NCGC00015883-11; NCGC00094352-01; NCGC00094352-02; NCGC00094352-03; NCGC00179257-01; AK172045; HY-11018; LY-03004; AB0004623; AB00514010; EU-0101074; FT-0631037; FT-0674432; SW197348-4; 4767-EP2269990A1; 4767-EP2272537A2; 4767-EP2272841A1; 4767-EP2275420A1; 4767-EP2275423A1; 4767-EP2280008A2; 4767-EP2280010A2; 4767-EP2298731A1; 4767-EP2298776A1; 4767-EP2301936A1; 4767-EP2308867A2; 4767-EP2308870A2; 4767-EP2308875A1; 4767-EP2316836A1; 66R062; D00426; J10290; Q-4040; AB00514010-09; AB00514010-11; AB00514010-12; AB00514010_13; AB00514010_14; A801409; L000510; Q412443; J-001555; SR-01000075399-2; SR-01000075399-8; BRD-K53857191-001-04-5; BRD-K53857191-001-10-2; Z1522566617; Risperidone, British Pharmacopoeia (BP) Reference Standard; Risperidone, European Pharmacopoeia (EP) Reference Standard; Risperidone, United States Pharmacopeia (USP) Reference Standard; Risperidone, Pharmaceutical Secondary Standard; Certified Reference Material
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| Clinical Status |
Approved
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| Disease Indication | Schizophrenia | ICD-11: 6A20 | [1] | ||
| PubChem CID | |||||
| Formula |
C23H27FN4O2
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| Canonical SMILES |
CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F
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| InChI |
1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3
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| InChIKey |
RAPZEAPATHNIPO-UHFFFAOYSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=5073"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 410.5 | Topological Polar Surface Area | 61.9 | |
| XlogP | 2.7 | Complexity | 731 | ||
| Heavy Atom Count | 30 | Rotatable Bond Count | 4 | ||
| Hydrogen Bond Donor Count | 0 | Hydrogen Bond Acceptor Count | 6 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
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| Risperidone 3 mg tablet | Click to Show/Hide the Full List of Formulation(s): 39 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Aspartame; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Sorbitol; Crospovidone; Silicon dioxide; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Stearic acid; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Aspartame; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Sorbitol; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Acesulfame potassium; Sodium stearyl fumarate; Aspartame; Fd&c yellow no. 6; Mannitol; Sodium chloride; Talc; Silicon dioxide; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Hydroxypropyl cellulose, low substituted; Magnesium aluminometasilicate type i-a; Peppermint
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Jubilant Cadista Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Acesulfame | DIG Info | Carbonic anhydrase IX (Ki = 2400 nM) | [10] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Lactose; Pigment yellow 3; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Fluorescein sodium; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Caraco Pharmaceutical Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Pigment yellow 3 | DIG Info | Colon cancer SW620 cells (IC50 = 450 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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Menthol; Aspartame; Magnesium stearate; Mannitol; Ferric oxide red; Magnesium carbonate; Talc; Croscarmellose sodium; Silicon dioxide; Hydroxypropyl cellulose, low substituted; Saccharin sodium
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Menthol | DIG Info | Transient receptor potential p8 (EC50 = 3000 nM) | [13] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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Aspartame; Magnesium stearate; Mannitol; Sorbitol; Tartaric acid; Talc; Croscarmellose sodium; Crospovidone; Silicon dioxide
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Ammonium glycyrrhizate; Acesulfame; Maltodextrin; Aspartame; Calcium stearate; Mannitol; Ferric oxide red; Sucrose; Croscarmellose sodium; Modified corn starch (1-octenyl succinic anhydride)
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Monoammonium glycyrrhizate | DIG Info | Dehydrogenase/reductase 9C 3 (IC50 = 0.4 nM) | [14] | |||
| Acesulfame | DIG Info | Carbonic anhydrase IX (Ki = 2400 nM) | [10] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [15] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; McKesson; Mylan Pharamceuticals; NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s); Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Ajanta Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Breckenridge Pharmaceutical; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Propylene glycol; Titanium dioxide; Hypromellose; Cellulose, microcrystalline; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Polyethylene glycol; Starch, corn
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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Sodium lauryl sulfate; Aspartame; Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline; Guar gum; Peppermint; Polacrilin potassium
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|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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Sodium lauryl sulfate; Aspartame; Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline; Guar gum; Polacrilin; Polacrilin potassium
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 23 |
DFM Info
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Lactose; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Clinical Solutions Wholesale; Qualitest Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Polyethylene glycol; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Cobalt Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Lactose; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Colloidal silicon dioxide; Polyethylene glycol; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Hikma Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | AvPAK; Cadila Healthcare; Clinical Solutions Wholesale; RemedyRepack; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Propylene glycol; Titanium dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; Aurolife Pharma; Citron Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 31 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Lactose; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Polyvinyl alcohol; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromellose 2910 (5 mpa.s); Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Drug Formulation 35 |
DFM Info
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|||||
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Glycine; Aspartame; Mannitol; Ferric oxide red; Sodium hydroxide; Carbomer homopolymer type c (allyl pentaerythritol crosslinked); Gelatin, unspecified; Peppermint oil; Xanthan gum
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Janssen Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Aminoethanoic acid | DIG Info | Glycine type-1 transporter (IC50 = 31600 nM) | [17] | |||
| Drug Formulation 36 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Flucloxacillin sodium monohydrate; Hypromellose 2208 (100 mpa.s); Peg-8 dioleate; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Tartaric acid; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 38 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (100 mpa.s); Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 39 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycol 8000; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Risperidone 2 mg tablet | Click to Show/Hide the Full List of Formulation(s): 42 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Aspartame; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Sorbitol; Crospovidone; Silicon dioxide; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; McKesson; Mylan Pharamceuticals; NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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Stearic acid; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Aspartame; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Sorbitol; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Sodium lauryl sulfate; Acesulfame potassium; Sodium stearyl fumarate; Aspartame; Fd&c blue no. 1; Mannitol; Sodium chloride; Talc; Silicon dioxide; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Hydroxypropyl cellulose, low substituted; Magnesium aluminometasilicate type i-a; Peppermint
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Jubilant Cadista Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Acesulfame | DIG Info | Carbonic anhydrase IX (Ki = 2400 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Polyethylene glycol; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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Lactose; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Pigment orange 2; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Orange; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Caraco Pharmaceutical Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Pigment orange 2 | DIG Info | Estrogen receptor alpha (IC50 = 709 nM) | [11] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Menthol; Aspartame; Magnesium stearate; Mannitol; Ferric oxide red; Magnesium carbonate; Talc; Croscarmellose sodium; Silicon dioxide; Hydroxypropyl cellulose, low substituted; Saccharin sodium
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Menthol | DIG Info | Transient receptor potential p8 (EC50 = 3000 nM) | [13] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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Aspartame; Magnesium stearate; Mannitol; Sorbitol; Tartaric acid; Talc; Croscarmellose sodium; Crospovidone; Silicon dioxide
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Ammonium glycyrrhizate; Acesulfame; Maltodextrin; Aspartame; Calcium stearate; Mannitol; Ferric oxide red; Sucrose; Croscarmellose sodium; Modified corn starch (1-octenyl succinic anhydride)
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Monoammonium glycyrrhizate | DIG Info | Dehydrogenase/reductase 9C 3 (IC50 = 0.4 nM) | [14] | |||
| Acesulfame | DIG Info | Carbonic anhydrase IX (Ki = 2400 nM) | [10] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [15] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Lactose; Sodium lauryl sulfate; Fd&c red no. 40; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Clinical Solutions Wholesale; Proficient Rx; Qualitest Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s); Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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Lactose monohydrate; Calcium carbonate; Magnesium stearate; Tartaric acid; Calcium sulfate; Ferric oxide red; Talc; Polyethylene glycol 3350; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Calcium carbonate | DIG Info | Carbonic anhydrase IX (Ki = 8600 nM) | [16] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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Lactose, anhydrous; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Aluminum oxide; Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; Janssen Pharmaceutical; PD-Rx Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose; Sodium lauryl sulfate; Fd&c red no. 40; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Propylene glycol; Titanium dioxide; Hypromellose; Cellulose, microcrystalline; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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Sodium lauryl sulfate; Aspartame; Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline; Guar gum; Peppermint; Polacrilin potassium
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 23 |
DFM Info
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Sodium lauryl sulfate; Aspartame; Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline; Guar gum; Polacrilin; Polacrilin potassium
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Ajanta Pharmaceutical; MSM Repackaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Breckenridge Pharmaceutical; NuCare Pharmaceuticals; Proficient Rx; RemedyRepack; TYA Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Lactose; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Polyvinyl alcohol; Colloidal silicon dioxide; Polyethylene glycol; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Hikma Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 28 |
DFM Info
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Stearic acid; Lactose; Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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Anhydrous lactose; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care; Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 30 |
DFM Info
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Lactose; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (100 mpa.s); Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | AvPAK; Cadila Healthcare; Clinical Solutions Wholesale; Lake Eire Medical & Surgical Supply DBA Quality Care Products; NuCare Pharmaceuticals; RemedyRepack; State of Florida DOH Central Pharmacy; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Propylene glycol; Titanium dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Hypromellose; Cellulose, microcrystalline; Colloidal silicon dioxide; Polyethylene glycol; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 35 |
DFM Info
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Sodium lauryl sulfate; Aspartame; Calcium stearate; Mannitol; Crospovidone; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Peppermint
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 36 |
DFM Info
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Sodium lauryl sulfate; Aspartame; Calcium stearate; Mannitol; Crospovidone; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Peppermint
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 38 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromellose 2910 (5 mpa.s); Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Drug Formulation 39 |
DFM Info
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Glycine; Aspartame; Mannitol; Ferric oxide red; Sodium hydroxide; Carbomer homopolymer type c (allyl pentaerythritol crosslinked); Gelatin, unspecified; Peppermint oil; Xanthan gum
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Janssen Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Aminoethanoic acid | DIG Info | Glycine type-1 transporter (IC50 = 31600 nM) | [17] | |||
| Drug Formulation 40 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycol 8000; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 41 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; Aurolife Pharma; Citron Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 42 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Polyethylene glycol; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Cobalt Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Risperidone 4 mg tablet | Click to Show/Hide the Full List of Formulation(s): 36 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Aspartame; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Mannitol; Sorbitol; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer
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|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
|
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
|
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; McKesson; Mylan Pharamceuticals; NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s); Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Hypromellose; Polyvinyl alcohol; Silicon dioxide; Polydextrose; Polyethylene glycol; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [9] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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Lactose; Sodium lauryl sulfate; D&c green no. 5; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Caraco Pharmaceutical Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| D&C green no. 5 | DIG Info | Solute carrier SLCO2B1 (Ki = 1.54 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Lactose; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Clinical Solutions Wholesale; Qualitest Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Aluminum oxide; Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Janssen Pharmaceutical; PD-Rx Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Menthol; Aspartame; Magnesium stearate; Mannitol; Ferric oxide red; Magnesium carbonate; Talc; Croscarmellose sodium; Silicon dioxide; Hydroxypropyl cellulose, low substituted; Saccharin sodium
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Menthol | DIG Info | Transient receptor potential p8 (EC50 = 3000 nM) | [13] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Aspartame; Magnesium stearate; Mannitol; Sorbitol; Tartaric acid; Talc; Croscarmellose sodium; Crospovidone; Silicon dioxide
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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Ammonium glycyrrhizate; Acesulfame; Maltodextrin; Aspartame; Calcium stearate; Mannitol; Ferric oxide red; Sucrose; Croscarmellose sodium; Modified corn starch (1-octenyl succinic anhydride)
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Monoammonium glycyrrhizate | DIG Info | Dehydrogenase/reductase 9C 3 (IC50 = 0.4 nM) | [14] | |||
| Acesulfame | DIG Info | Carbonic anhydrase IX (Ki = 2400 nM) | [10] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [15] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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Sodium lauryl sulfate; Acesulfame potassium; Sodium stearyl fumarate; Aspartame; Mannitol; Ferric oxide red; Sodium chloride; Talc; Silicon dioxide; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Hydroxypropyl cellulose, low substituted; Magnesium aluminometasilicate type i-a; Peppermint
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Jubilant Cadista Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Acesulfame | DIG Info | Carbonic anhydrase IX (Ki = 2400 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 1; Fd&c yellow no. 5; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Polyethylene glycol; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Cobalt Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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Lactose, unspecified form; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Propylene glycol; Titanium dioxide; Hypromellose; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | AvPAK; Cadila Healthcare; Clinical Solutions Wholesale; State of Florida DOH Central Pharmacy; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 23 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Propylene glycol; Titanium dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; Aurolife Pharma; Citron Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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Sodium lauryl sulfate; Aspartame; Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline; Guar gum; Peppermint; Polacrilin potassium
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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Sodium lauryl sulfate; Aspartame; Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline; Guar gum; Polacrilin; Polacrilin potassium
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Ajanta Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 28 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Breckenridge Pharmaceutical; RemedyRepack; TYA Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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Lactose; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (100 mpa.s); Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 30 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 31 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromellose 2910 (5 mpa.s); Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Drug Formulation 33 |
DFM Info
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Lactose; Sodium lauryl sulfate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Triacetin; Colloidal silicon dioxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (50 mpa.s); Hypromellose 2910 (6 mpa.s); Polydextrose; Polyethylene glycol; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Hikma Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 34 |
DFM Info
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Glycine; Aspartame; Mannitol; Ferric oxide red; Sodium hydroxide; Carbomer homopolymer type c (allyl pentaerythritol crosslinked); Gelatin, unspecified; Peppermint oil; Xanthan gum
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Janssen Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Aminoethanoic acid | DIG Info | Glycine type-1 transporter (IC50 = 31600 nM) | [17] | |||
| Drug Formulation 35 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycol 8000; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 36 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Tartaric acid; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Risperidone 0.5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 41 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | McKesson; Mylan Pharamceuticals; NCS HealthCare of KY, Inc dba Vangard Labs; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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Stearic acid; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Aspartame; Magnesium stearate; Mannitol; Sorbitol; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Menthol; Aspartame; Magnesium stearate; Mannitol; Ferric oxide red; Magnesium carbonate; Talc; Croscarmellose sodium; Silicon dioxide; Hydroxypropyl cellulose, low substituted; Saccharin sodium
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Menthol | DIG Info | Transient receptor potential p8 (EC50 = 3000 nM) | [13] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Aspartame; Magnesium stearate; Mannitol; Sorbitol; Tartaric acid; Talc; Croscarmellose sodium; Crospovidone; Silicon dioxide
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Ammonium glycyrrhizate; Acesulfame; Maltodextrin; Aspartame; Calcium stearate; Mannitol; Ferric oxide red; Sucrose; Croscarmellose sodium; Modified corn starch (1-octenyl succinic anhydride)
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Monoammonium glycyrrhizate | DIG Info | Dehydrogenase/reductase 9C 3 (IC50 = 0.4 nM) | [14] | |||
| Acesulfame | DIG Info | Carbonic anhydrase IX (Ki = 2400 nM) | [10] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [15] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Sodium lauryl sulfate; Acesulfame potassium; Sodium stearyl fumarate; Aspartame; Mannitol; Ferric oxide yellow; Sodium chloride; Talc; Silicon dioxide; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Hydroxypropyl cellulose, low substituted; Magnesium aluminometasilicate type i-a; Peppermint
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|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Jubilant Cadista Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Acesulfame | DIG Info | Carbonic anhydrase IX (Ki = 2400 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Lactose; Sodium lauryl sulfate; Magnesium stearate; D&c brown no. 1; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; 3,4,9,10-perylenetetracarboxylic diimide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Caraco Pharmaceutical Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| D&C brown no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 2.8 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s); Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Breckenridge Pharmaceutical; Proficient Rx; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Ajanta Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; Aurolife Pharma; Citron Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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Sodium lauryl sulfate; Aspartame; Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline; Guar gum; Peppermint; Polacrilin potassium
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Sodium lauryl sulfate; Aspartame; Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline; Guar gum; Polacrilin; Polacrilin potassium
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Polyethylene glycol; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose, anhydrous; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Lactose; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Clinical Solutions Wholesale; Proficient Rx; Qualitest Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Propylene glycol; Titanium dioxide; Hypromellose; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Sodium lauryl sulfate; Aspartame; Calcium stearate; Mannitol; Crospovidone; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Peppermint
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Sodium lauryl sulfate; Aspartame; Calcium stearate; Mannitol; Crospovidone; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Peppermint
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Polyvinyl alcohol; Colloidal silicon dioxide; Polyethylene glycol; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Hikma Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Propylene glycol; Talc; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromellose 2910 (5 mpa.s); Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Sodium starch glycolate type a potato; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 34 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | AvPAK; Cadila Healthcare; Cardinal Health; TYA Pharmaceuticals; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 35 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Propylene glycol; Titanium dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 36 |
DFM Info
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Glycine; Aspartame; Mannitol; Ferric oxide red; Sodium hydroxide; Carbomer homopolymer type c (allyl pentaerythritol crosslinked); Gelatin, unspecified; Peppermint oil
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Janssen Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Aminoethanoic acid | DIG Info | Glycine type-1 transporter (IC50 = 31600 nM) | [17] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Tartaric acid; Ferric oxide red; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 38 |
DFM Info
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Anhydrous lactose; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 39 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (100 mpa.s); Sodium starch glycolate type a potato; Starch, corn
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 40 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Polyethylene glycol; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cobalt Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 41 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycol 8000; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Risperidone 1 mg tablet | Click to Show/Hide the Full List of Formulation(s): 44 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Stearic acid; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Aspartame; Magnesium stearate; Mannitol; Sorbitol; Crospovidone; Silicon dioxide; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Stearic acid; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Aspartame; Magnesium stearate; Mannitol; Sorbitol; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Menthol; Aspartame; Magnesium stearate; Mannitol; Ferric oxide red; Magnesium carbonate; Talc; Croscarmellose sodium; Silicon dioxide; Hydroxypropyl cellulose, low substituted; Saccharin sodium
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Menthol | DIG Info | Transient receptor potential p8 (EC50 = 3000 nM) | [13] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Aspartame; Magnesium stearate; Mannitol; Sorbitol; Tartaric acid; Talc; Croscarmellose sodium; Crospovidone; Silicon dioxide
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Ammonium glycyrrhizate; Acesulfame; Maltodextrin; Aspartame; Calcium stearate; Mannitol; Ferric oxide red; Sucrose; Croscarmellose sodium; Modified corn starch (1-octenyl succinic anhydride)
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Monoammonium glycyrrhizate | DIG Info | Dehydrogenase/reductase 9C 3 (IC50 = 0.4 nM) | [14] | |||
| Acesulfame | DIG Info | Carbonic anhydrase IX (Ki = 2400 nM) | [10] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [15] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Cardinal Health; McKesson; Mylan Pharamceuticals; NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Sodium lauryl sulfate; Acesulfame potassium; Sodium stearyl fumarate; Aspartame; Mannitol; Sodium chloride; Talc; Silicon dioxide; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Hydroxypropyl cellulose, low substituted; Magnesium aluminometasilicate type i-a; Peppermint
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|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Jubilant Cadista Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Acesulfame | DIG Info | Carbonic anhydrase IX (Ki = 2400 nM) | [10] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s); Sodium starch glycolate type a potato; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Sodium lauryl sulfate; Aspartame; Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline; Guar gum; Peppermint; Polacrilin potassium
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Sodium lauryl sulfate; Aspartame; Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline; Guar gum; Polacrilin; Polacrilin potassium
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Stearic acid; Lactose; Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Clinical Solutions Wholesale; McKesson; Qualitest Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Polyethylene glycol; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Propylene glycol; Titanium dioxide; Hypromellose; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose, anhydrous; Sodium lauryl sulfate; Magnesium stearate; Propylene glycol; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Propylene glycol; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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Lactose; Sodium lauryl sulfate; Magnesium stearate; Propylene glycol; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Department Of Health Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Propylene glycol; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose; Sodium lauryl sulfate; Magnesium stearate; Propylene glycol; Silicon dioxide; Cellulose, microcrystalline; Gray conger; Hypromelloses; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Caraco Pharmaceutical Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Propylene glycol; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 23 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Propylene glycol; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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Sodium lauryl sulfate; Aspartame; Calcium stearate; Mannitol; Crospovidone; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Peppermint
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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Sodium lauryl sulfate; Aspartame; Calcium stearate; Mannitol; Crospovidone; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Peppermint
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Cadila Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromellose 2910 (5 mpa.s); Starch, corn
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose; Sodium lauryl sulfate; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Colloidal silicon dioxide; Polyethylene glycol; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Hikma Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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Glycine; Aspartame; Mannitol; Ferric oxide red; Sodium hydroxide; Carbomer homopolymer type c (allyl pentaerythritol crosslinked); Gelatin, unspecified; Peppermint oil
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Janssen Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Aminoethanoic acid | DIG Info | Glycine type-1 transporter (IC50 = 31600 nM) | [17] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | AvPAK; Cadila Healthcare; Cardinal Health; Clinical Solutions Wholesale; DirectRX; State of Florida DOH Central Pharmacy; TYA Pharmaceuticals; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Propylene glycol; Titanium dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Sodium starch glycolate type a potato; Starch, corn
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 35 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Ajanta Pharmaceutical; Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 36 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Breckenridge Pharmaceutical; Proficient Rx; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Tartaric acid; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 38 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 39 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (100 mpa.s); Sodium starch glycolate type a potato; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 40 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Hypromellose 2208 (100 mpa.s); Microcrystalline cellulose; Sodium starch glycolate type a potato; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 41 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Polyethylene glycol; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cobalt Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 42 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; Citron Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 43 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s)
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aurolife Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 44 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycol 8000; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Risperidone 0.25 mg tablet | Click to Show/Hide the Full List of Formulation(s): 31 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Stearic acid; Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Aspartame; Magnesium stearate; Mannitol; Sorbitol; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Aspartame; Magnesium stearate; Mannitol; Sorbitol; Tartaric acid; Talc; Croscarmellose sodium; Crospovidone; Silicon dioxide
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [4] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol
|
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | McKesson; Mylan Pharamceuticals; NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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Lactose; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Clinical Solutions Wholesale; Proficient Rx; Qualitest Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Lactose; Pigment yellow 3; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Fluorescein sodium; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Caraco Pharmaceutical Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Pigment yellow 3 | DIG Info | Colon cancer SW620 cells (IC50 = 450 nM) | [12] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Polyethylene glycol 400; Polyethylene glycol 6000; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s); Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Breckenridge Pharmaceutical; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Ajanta Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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Lactose, unspecified form; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Wockhardt | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Ferric oxide yellow; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Polyethylene glycol; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | West-Ward Pharmaceticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; Janssen Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; Aurolife Pharma; Citron Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare; Cardinal Health; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Proficient Rx; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Propylene glycol; Titanium dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromellose 2910 (5 mpa.s); Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Drug Formulation 23 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Hypromellose; Cellulose, microcrystalline; Polyethylene glycol; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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Lactose; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Polyvinyl alcohol; Colloidal silicon dioxide; Polyethylene glycol; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Hikma Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Tartaric acid; Ferric oxide yellow; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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Anhydrous lactose; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 28 |
DFM Info
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Lactose; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2208 (100 mpa.s); Sodium starch glycolate type a potato; Starch, potato
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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Lactose, unspecified form; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Polyethylene glycol 400; Silicon dioxide; Hypromellose 2208 (100 mpa.s); Microcrystalline cellulose; Sodium starch glycolate type a potato; Starch, potato
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [8] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Polyethylene glycol; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Cobalt Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 31 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycol 8000; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
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